J-GLOBAL         Last updated: Feb 23, 2017 at 19:23
Teikyo University of Science & Technology
Faculty of Medical Sciences
Job title
Ph.D.(*Yamanashi Medical University*)

Research Areas


Academic & Professional Experience

Yamanashi Medical University, Research
Ruhr-Universität-Bochum, Research
Max-Planck-Institut für Physiologishe


Graduate School, Division of Natural Science, Hokkaido University
Faculty of Science, Hokkaido University
Oita National College of Technology

Committee Memberships

Physiological Society of Japan  Council
Japanese Society of Biometeorology  Director
Japanese Society of Adaptation Medicine  Council

Published Papers

Does Jin-Oh-Sui (mineral water) improve serum triglyceride levels? A pilot study.
Fujita, Y., Inoue, K., Amano, H., Uchida, T., Moriyama, S., Hashimoto, M.
Shimane J. Med. Sci.   30 87-93   2014   [Refereed]
The seasonality and the fasting effect in raccoon dog (Nyctereutes procyonoides) serum leptin levels determined by canine-leptin-specific ELISA.
Kitao, N., Fukui, D., Shibata, H., Saito, M., Osborne, P.G., Hashimoto, M.
J Exp Zool   315 84-89   2011   [Refereed]
Kitao, N,. Fukui, D., Hashimoto, M., Osborne, P.G.
Int J Biometeorol   53 159-165   2009   [Refereed]
Osborne, P.G., Hashimoto, M.
J Neurochem   106 1888-1899   2008   [Refereed]
Yamamoto, N., Hashimoto, M.
Int J Biometeorol   52 109-116   2007   [Refereed]
Osborne, P.G., Hashimoto, M.
Behav Brain Res   178 115-122   2007   [Refereed]
Yamamoto N, Hashimoto M.
Int J Biometeorol   51 201-208   2007   [Refereed]
Osborne PG, Hashimoto M.
Behav Brain Res   168 208-214   2006   [Refereed]
Osborne PG, Sato J, Shuke N, Hashimoto M.
Am J Physiol   289 R554-R562   2005   [Refereed]
Osborne PG, Gao B, Hashimoto M.
Jpn J Physiol   54 295-305   2004   [Refereed]
Gao B, Kikuchi-Utumi K, Ohinata H, Hashimoto M, Kuroshima A.
Jpn J Physiol   53 205-213   2003   [Refereed]
Enhanced gene expression of endothelial nitric oxide synthase in brown adipose tissue during cold exposure.
Kikuchi-Utsumi K, Gao B, Ohinata H, Hashimoto M, Yamamoto N, Kuroshima A.
Am J Physiol   282 R623-R626   2002   [Refereed]
Hashimoto M, Gao B, Kikuchi-Utsumi K, Ohinata H, Osborne PG.
J Thermal Biol   27 55-67   2002   [Refereed]
Hashimoto M, Kuroshima A, Arita J, Shibata M.
J Thermal Biol   24 347-350   1999   [Refereed]
Shibata M, Uno T, Hashimoto M.
Brain Res   833 242-250   1999   [Refereed]
Izaki M, Hashimoto M, Arita J.
Neurosci Lett   260 146-148   1999   [Refereed]
Spontaneous activity of preoptic neurons in slice preparationsof the hypothalamus of European hamsters (Cricetus cricetus) and Wistar rats under different states of hypothermia.
Hashimoto M, Schmid HA, Ohwatari N, Pleschka K.
Cryobiology   34 254-262   1998   [Refereed]
Heterogeneous action of vasopressin on angiotensin II sensitive neurons in the subfornical organs of rats.
Anthes N, Schmid HA, Hashimoto M, Riediger T, Simon E.
Am J Physiol   273 R2105-R2111   1997   [Refereed]
Does interleukin-1 mediate tumour necrosis factor alpha-induced fever in rabbits?
Hashimoto M, Sakakibara Y, Iriki M, Goto F, Shimada Y.
Pflugers Arch   427 365-372   1994   [Refereed]
What roles dose the organum vasculosum laminae terminalis play in fever in rabbits?
Hashimoto M, Ueno T, Iriki M.
Pflugers Arch   429 50-57   1994   [Refereed]
Intraperitoneal injection of 1-oleoyl-2-docosahexaenoyl phosphatidylcholine stimulates discriminatory shock avoidance learning in rats.
Izaki M, Hashimoto M, Iriki M, Hibino H.
Neurosci Lett   167 171-174   1994   [Refereed]
Effects of halothane and enflurane on the peritoneal vasoconstriction and shivering induced by internal body cooling in rabbits.
Matsukawa T, Kashimoto S, Kumazawa T, Miyaji T, Hashimoto M, Iriki M.
J Anesthesia   8 311-315   1994   [Refereed]
Hashimoto M, Gong X-W, Izaki M, Iriki M, Hibino H.
Neurosci Lett   158 29-32   1993   [Refereed]
Action site of circulating interleukin-1 on the rabbit brain.
Hashimoto M, Ishikawa Y, Yokota S, Goto F, Bando T, Sakakibara Y, Iriki M.
Brain Res   540 217-223   1991   [Refereed]
Characterization and mechanism of fever induction by interleukin-1 beta.
Hashimoto M
Pflugers Arch   419 616-621   1991   [Refereed]
Effect of indomethacin on febrile response to recombinant human interleukin 1-a in rabbits.
Hashimoto M, Bando T, Iriki M, Hashimoto K
Am J Physiol   255 R527-R533   1988   [Refereed]
Sympathetic controlof blood flow to AVAs and facial tissues supplied by the internal maxillary artery in dogs.
Hashimoto M, Sommerlad U, Pleschka K.
Pflugers Arch   410 589-595   1987   [Refereed]
Distribution of facial and nasal blood flow in the cold loaded dog.
Pleschka K, Hashimoto M, Sommerlad U, Lurkens I
J Therm Biol   12 113-117   1987   [Refereed]
Threshold dissociation of thermoregulatory effector responses in febrile rabbits.
Iriki M, Hashimoto M, Saigusa T
Can J Physiol Pharmacol   65 1304-1311   1987   [Refereed]
Vascular and metabolic responses to body core cooling in the rabbit pretreated with 5,7-dihydroxytryptamine.
Nagai M, Hashimoto M, Iriki M
Autonom Nerv Sys   23 219-222   1986   [Refereed]
Comparison of the action of prostaglandin with endotoxin on thermoregulatory response thresholds.
Hashimoto M, Nagai M, Iriki M.
Pflugers Arch   405 1-4   1985   [Refereed]


Japanese journal of biometeorology   43(1) 23-33   May 2006
Effect of regular exercise on cold-induced vasodilation.
Annalen der Meteorologie   41 vol.1(: 447-450)    2005

Books etc

Physiology of CO2-hot-spring bathing: analysis using artificially made CO2-hot-spring water and experimental animals.
Annalen der Meteorologie   2005   
Brown adipose tissue and nonshivering thermogenesis in stressful states. In: Thermotherapy for Neoplasia, Inflammation, and Pain.
Springer   2001   
Autonomic and endocrine adjustments in fever.
Thermotherapy for Neoplasia, Inflammation, and Pain.   2001   
Sympathetic responses during fever
Body temperature and metabolism   1995   
Comparison of the pyrogenicety between IL-1 and TNF
Thermal Physiology   1989   


Studies on the preferred ambient temperature for the aged-an experimental approach to the effect of ambient temperature on sleep in the aged
1989 - 1991
Developmental study of the measuring system of metabolic rate for small animals

Research Grants & Projects

Analysis of the neuronal and molecular mechanisms controlling hibernation for application to human medicine.
Grant-in-Aid for Scientific Research
Evaluation of the physiological background of carbon dioxide balneotherapy.
Grant-in-Aid for Promotion of Private Scientific Research