小塚諭 (Satoshi Kozuka) - マイポータル - researchmap

基本情報

所属: 至学館大学健康科学部栄養科学科助教授

学位: 医学博士(名古屋市立大学)

J-GLOBAL ID: 200901080216062622
researchmap会員ID: 1000054908

研究キーワード

4

研究分野

3

経歴

4

1991年 - 2000年

名古屋市立大学学内講師
1991年 - 2000年

名古屋市立大学
1977年 - 1991年

名古屋市立大学助手
1977年 - 1991年

名古屋市立大学

学歴

1

- 1975年

名古屋保健衛生大学, 衛生学部, 衛生技術学

MISC

28

Mucosal immunization against hepatitis B virus by intranasal co-administration of recombinant hepatitis B surface antigen and recombinant cholera toxin B subunit as an adjuvant

M Isaka, Y Yasuda, M Mizokami, S Kozuka, T Taniguchi, K Matano, J Maeyama, K Mizuno, K Morokuma, K Ohkuma …

VACCINE 19(11-12) 1460-1466 2001年1月
Cytokine responses to recombinant cholera toxin B subunit produced by Bacillus brevis as a mucosal adjuvant

J Maeyama, M Isaka, Y Yasuda, K Matano, S Kozuka, T Taniguchi, K Ohkuma, K Tochikubo, N Goto

MICROBIOLOGY AND IMMUNOLOGY 45(2) 111-117 2001年
Efficient extracellular production of recombinant ┣DBEscherichia coli(/)-┫DB heat-labile enterotoxin B subunit by using expression/secretion system of ┣DBBacillus brevis(/)-┫DB and its mucosal immunoadjuvant activity.

Vaccine 18(17) 1730-1733 2000年
Efficient extracellular production of recombinant ┣DBEscherichia coli(/)-┫DB heat-labile enterotoxin B subunit by using expression/secretion system of ┣DBBacillus brevis(/)-┫DB and its mucosal immunoadjuvant activity.

Vaccine 18(17) 1730-1733 2000年
Safety evaluation of recombinant cholera toxinB subunit produced by ┣DBBacillus brevis(/)-┫DB as a mucosal adjuvant.

Vaccine 18(18) 2168-2171 2000年
Induction of systemic and mucosal antibody responses in mice immunized intranasally with aluminium-non-adsorbed diphtheria toxoid together with recombinant cholera toxin B subunit as an adjuvant

Masanori Isaka, Yoko Yasuda, Satoshi Kozuka, Tooru Taniguchi, Keiko Matano, Jun-Ichi Maeyama, Takako Komiya, Kunio Ohkuma, Norihisa Goto, Kunio Tochikubo

Vaccine 18(7-8) 743-751 1999年11月12日
Expression of a germination-specific amidase, SleB, of bacilli in the forespore compartment of sporulating cells and its localization on the exterior side of the cortex in dormant spores

R Moriyama, H Fukuoka, S Miyata, S Kudoh, A Hattori, S Kozuka, Y Yasuda, K Tochikubo, S Makino

JOURNAL OF BACTERIOLOGY 181(8) 2373-2378 1999年4月
Intranasal or subcutaneous co-administration of recombinant cholera toxin B subunit stimulates only a slight or no level or the specific IgE response in mice to tetanus toxoid

M Isaka, Y Yasuda, S Kozuka, T Taniguchi, Y Miura, K Matano, N Goto, K Tochikubo

VACCINE 17(7-8) 944-948 1999年2月
Systemic and mucosal immune responses of mice to aluminium-adsorbed or aluminium-non-adsorbed tetanus toxoid administered intranasally with recombinant cholera toxin B subunit

Masanori Isaka, Yoko Yasuda, Satoshi Kozuka, Yutaka Miura, Tooru Taniguchi, Keiko Matano, Norihisa Goto, Kunio Tochikubo

Vaccine 16(17) 1620-1626 1998年10月
A spore coat protein, CotS, of Bacillus subtilis is synthesized under the regulation of sigma(K) and GerE during development and is located in the inner coat layer of spores

H Takamatsu, Y Chikahiro, T Kodama, H Koide, S Kozuka, K Tochikubo, K Watabe

JOURNAL OF BACTERIOLOGY 180(11) 2968-2974 1998年6月
Cloning of a novel gene yrb B, encoding a protein located in the spore integument of ┣DBBacillus(/)-┫DB ┣DBsubtilis(/)-┫DB.

FEMS Microbiology Letters 166(2) 361-367 1998年
Recombinant cholera toxin B subunit acts as an adjuvant for the mucosal and systemic responses of mice to mucosally co-administered bovine serum albumin

K Tochikubo, M Isaka, Y Yasuda, S Kozuka, K Matano, Y Miura, T Taniguchi

VACCINE 16(2-3) 150-155 1998年1月
Localization of germination-specific spore-lytic enzymes in Clostridium perfringens S40 spores detected by immunoelectron microscopy

S Miyata, S Kozuka, Y Yasuda, YH Chen, R Moriyama, K Tochikubo, S Makino

FEMS MICROBIOLOGY LETTERS 152(2) 243-247 1997年7月
Expression and secretion of the S2 subunit of pertussis toxin in ┣DBBacillus(/)-┫DB ┣DBbrevis(/)-┫DB

Vaccine 14(17-18) 1707 1996年
セレウス菌芽胞のフィラメント状アペンデジの断片化と可溶化

小塚諭

日本細菌学雑誌 48(3) 541-550 1993年
Fragmentation and solubilization of filamentous appendages of ┣DBBacillus(/)-┫DB ┣DBcereus(/)-┫DB.

Satoshi KOZUKA

Japanese Journal of Bacteriology 48(3) 541-550 1993年
Permeability of Dormant Spores of ┣DBBacillus(/)-┫DB ┣DBsubtilis(/)-┫DB to Malachite Green and Crystal Violet.

Journal of General Microbiology 137(3) 1991年
Presence of Proteins Derived from the Vegetative Cell Membrane in the Dormant Spore Coat of ┣DBBacillus(/)-┫DB ┣DBsubtilis(/)-┫DB.

Microbiology and Immunology 33(5) 1989年
芽胞(細菌胞子)の微細構造

栃久保邦夫, 安田陽子, 小塚諭, 藤田祐子

電子顕微鏡 23(1) 9-17 1988年
A spore coat protein, CotS, of Bacillus subtilis is synthesized under the regulation of σ^-K and GerE during development and is located in the unner coat layer of spores.

Journal of Bacteriology 180(11) 2968-2974 1988年

もっとみる

書籍等出版物

2

食品環境実験50

医歯薬出版 1999年
イラスト食品衛生学

東京教学社 1999年

所属学協会

5

Works(作品等)

2

共同研究・競争的資金等の研究課題

8

機能性食品の抗菌・殺菌活性の研究

共同研究 2000年
A research of anti-bacterial and bacteriocidal activity of functional foods.

Cooperative Research 2000年
Bacillus brevisを用いた経口または経鼻投与可能な遺伝子組換えワクチンの作製

共同研究 1995年
Production of recombinant vaccine for a potencially intranasal or oral administration by Bacillus brevis.

Cooperative Research 1995年
免疫電子顕微鏡法による細菌内部における特異抗原の検索

共同研究 1990年
A research of specific antigen in the bacterial cell by immuno-electron microscopic method.

Cooperative Research 1990年
黄色ブドウ球菌食中毒の発生メカニズム
機能性食品の抗菌・殺菌活性