YAMANISHI Kiyofumi Last updated: Dec 3, 2018 at 16:46
Research Interests
Pustular psoriasis(1) ,
interleukin 33(4) ,
transglutaminase(4) ,
skin disease models(1) ,
keratinization disorders(1) ,
Genetic diagnosis(18) ,
Next generation sequencing(15) ,
Atopic dermatitis(50) ,
Psoriasis(16) ,
Palmoplantar pustulosis(3) ,
Bullous disorders(1) ,
Dermatology(178) ,
Molecular Biology(974) ,
Medical chemistry(7) Academic & Professional Experience
Dec 2003
-
Today
Professor and Chair, Department of Dermatology, Hyogo College of Medicine
Sep 2002
-
Nov 2003
Associate Professor, Department of Dermatology, Mie University School of Medicine
Apr 1991
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Aug 2002
Lecturer, Department of Dermatology, Kyoto Prefectural University of Medicine
Jul 1987
-
Mar 1991
Research Associate, Department of Dermatology, Kyoto Prefectural University of Medicine
Apr 1987
-
Jun 1987
Department of Dermatology, Kyoto Prefectural University of Medicine Hospital
Education
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1985
Kyoto Prefectural University of Medicine
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1981
Faculty of Medicine, Kyoto Prefectural University of Medicine
Committee Memberships
American Academy of Dermatology Member
Published Papers
Fujita H, Terui T, Hayama K, Akiyama M, Ikeda S, Mabuchi T, Ozawa A, Kanekura T, Kurosawa M, Komine M, Nakajima K, Sano S, Nemoto O, Muto M, Imai Y, Yamanishi K, Aoyama Y, Iwatsuki K, Japanese Dermatological Association Guidelines Development Committee for the Guidelines for the Management and Treatment of Generalized Pustular Psoriasis.
The Journal of dermatology 45(11) 1235-1270 Nov 2018 [Refereed]
Furukawa T, Matsui K, Kitano M, Yokoyama Y, Sekiguchi M, Azuma N, Imai Y, Hirota S, Yamanishi K, Sano H
Modern rheumatology 1-8 Sep 2018 [Refereed]
Wada Y, Kusakabe M, Nagai M, Imai Y, Yamanishi K
The Journal of dermatology Aug 2018 [Refereed]
Ryu WI, Lee H, Bae HC, Jeon J, Ryu HJ, Kim J, Kim JH, Son JW, Kim J, Imai Y, Yamanishi K, Jeong SH, Son SW
Journal of dermatological science 90(3) 313-322 Jun 2018 [Refereed]
Nagai M, Imai Y, Yamanishi K
The Journal of dermatology Jun 2018 [Refereed]
Kusakabe M, Imai Y, Natsuaki M, Yamanishi K
Acta dermato-venereologica 98(2) 278-279 Feb 2018 [Refereed]
Yamanishi K
International journal of dermatology 57(2) e1 Feb 2018 [Refereed]
Kanekura T, Seishima M, Honma M, Etou T, Eto H, Okuma K, Okubo Y, Yamaguchi Y, Kambara T, Mabuchi T, Suga Y, Morita A, Yamanishi K, Tsuruta D, Itoh K, Yamaji K, Ikeda S
The Journal of dermatology 44(12) 1353-1359 Dec 2017 [Refereed]
Wada Y, Kusakabe M, Nagai M, Yamamoto M, Imai Y, Ide YH, Hirota S, Yamanishi K
The Journal of dermatology 44(11) e282-e283 Nov 2017 [Refereed]
Imai Y, Hosotani Y, Ishikawa H, Yasuda K, Nagai M, Jitsukawa O, Gomi F, Nakanishi K, Yoshimoto T, Nakamura T, Yamanishi K
Scientific reports 7(1) 10053 Aug 2017 [Refereed]
Natsuaki M, Takada N, Kawabata H, Ando S, Yamanishi K
The Journal of dermatology 41 834-836 Sep 2014 [Refereed]
Kawasaki K, Yamanishi K, Yamada H
International journal of dermatology 54 295-301 Mar 2015 [Refereed]
Nagai M, Nagai H, Tominaga C, Sakaguchi Y, Jitsukawa O, Ohgo N, Nishigori C, Yamanishi K
Acta dermato-venereologica Nov 2014 [Refereed]
Inoue Y, Yamamoto M, Sakaguchi Y, Jitsukawa O, Hayano K, Yamane M, Sakamoto M, Yamanishi K
Acta dermato-venereologica Feb 2015 [Refereed]
Ide YH, Tsukamoto Y, Ito T, Watanabe T, Nakagawa N, Haneda T, Nagai M, Yamanishi K, Hirota S
Pathology, research and practice 211 415-420 May 2015 [Refereed]
Suga Y, Tsuda T, Nagai M, Sakaguchi Y, Jitsukawa O, Yamamoto M, Hitomi K, Yamanishi K
The Journal of dermatology Mar 2015 [Refereed]
Imai Y, Yasuda K, Sakaguchi Y, Futatsugi-Yumikura S, Yoshimoto T, Nakanishi K, Yamanishi K
Journal of dermatological science 74 159-161 May 2014 [Refereed]
Konishi T, Tsuda T, Sakaguchi Y, Imai Y, Ito T, Hirota S, Yamanishi K
The Journal of dermatology 41 258-261 Mar 2014 [Refereed]
Itoh M, Tatsukawa H, Eun-Seo L, Yamanishi K, Kojima S, Hitomi K
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 61 793-801 Nov 2013 [Refereed]
Washio K, Fukunaga A, Terai M, Hitomi K, Yamanishi K, Nishigori C
Acta dermato-venereologica Oct 2013 [Refereed]
Imai Y, Yasuda K, Sakaguchi Y, Haneda T, Mizutani H, Yoshimoto T, Nakanishi K, Yamanishi K
Proceedings of the National Academy of Sciences of the United States of America 110 13921-13926 Aug 2013 [Refereed]
Yoshimi N, Imai Y, Kakuno A, Tsubura A, Yamanishi K, Kurokawa I
International journal of dermatology Jun 2013 [Refereed]
Imai Y, Aochi S, Iwatsuki K, Sano H, Yamanishi K
The Journal of dermatology 40(4) 294-296 Feb 2013 [Refereed]
Haneda T, Imai Y, Koga H, Hashimoto T, Yamanishi K
The Journal of dermatology 40(4) 283-285 Jan 2013 [Refereed]
Yamamoto M, Imai Y, Sakaguchi Y, Haneda T, Yamanishi K
Disease markers 34 153-161 Jan 2013 [Refereed]
Oshimo T, Fukai K, Abe Y, Hozumi Y, Yokoi T, Tanaka A, Yamanishi K, Ishii M, Suzuki T
The Journal of dermatology 39(12) 1022-1025 Dec 2012 [Refereed]
Yoshimi N, Kurokawa I, Kakuno A, Tsubura A, Yamanishi K
The Journal of dermatology 39(8) 744-745 Aug 2012 [Refereed]
Yamamoto M, Tsuda T, Otaki Y, Nakanishi T, Yamanishi K
The Journal of dermatology 39(8) 716-718 Aug 2012 [Refereed]
Takei-Taniguchi R, Imai Y, Ishikawa C, Sakaguchi Y, Nakagawa N, Tsuda T, Hollenberg MD, Yamanishi K
The Journal of dermatology 39(7) 625-631 Jul 2012 [Refereed]
Nakagawa N, Yamamoto M, Imai Y, Sakaguchi Y, Takizawa T, Ohta N, Yagi N, Hatta I, Hitomi K, Takizawa T, Takeda J, Tsuda T, Matsuki M, Yamanishi K
Journal of dermatological science 65 196-206 Mar 2012 [Refereed]
Otani N, Yamanishi K, Sakaguchi Y, Imai Y, Shima M, Okuno T
Journal of immunological methods 377 53-55 Mar 2012 [Refereed]
Imai Y, Tsuda T, Aochi S, Futatsugi-Yumikura S, Sakaguchi Y, Nakagawa N, Iwatsuki K, Yamanishi K
Journal of dermatological science 64 75-77 Oct 2011 [Refereed]
Aochi S, Tsuji K, Sakaguchi M, Huh N, Tsuda T, Yamanishi K, Komine M, Iwatsuki K
Journal of the American Academy of Dermatology 64(5) 879-887 May 2011 [Refereed]
Itoh M, Kawamoto T, Tatsukawa H, Kojima S, Yamanishi K, Hitomi K
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 59(2) 180-187 Feb 2011 [Refereed]
Yamamoto M, Imai Y, Nakagawa N, Yamanishi K
The Journal of dermatology 38(2) 190-191 Feb 2011 [Refereed]
Omoto Y, Yamanaka K, Tokime K, Kitano S, Kakeda M, Akeda T, Kurokawa I, Gabazza EC, Tsutsui H, Katayama N, Yamanishi K, Nakanishi K, Mizutani H
Journal of dermatological science 59(2) 129-135 Aug 2010 [Refereed]
Erratum to "Neutrophil-dominant psoriasis-like skin inflammation induced by epidermal-specific expression of Raf in mice" [J. Dermatol. Sci. 58 (2010) 28-35].
Tartutani M, Imai Y, Yasuda K, Tsutsui H, Nakanishi K, Yamanishi K
Journal of dermatological science 59 64-71 Jul 2010 [Refereed]
Tarutani M, Imai Y, Yasuda K, Tsutsui H, Nakanishi K, Yamanishi K
Journal of dermatological science 58(1) 28-35 Apr 2010 [Refereed]
Azuma N, Natsuaki M, Yamanishi K, Kondo N, Iwasaki T, Morimoto M, Nishioka A, Sekiguchi M, Kitano M, Hashimoto N, Matsui K, Sano H
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 33(3) 149-153 2010 [Refereed]
Ishikawa C, Tsuda T, Konishi H, Nakagawa N, Yamanishi K
Antimicrobial agents and chemotherapy 53 1760-1765 May 2009 [Refereed]
Fujimoto T, Tsuda T, Yamamoto M, Tarutani M, Natsuaki M, Minami S, Ito T, Kozuka T, Yamanishi K
Journal of the European Academy of Dermatology and Venereology : JEADV 23 202-203 Feb 2009 [Refereed]
Sugimura Y, Hosono M, Kitamura M, Tsuda T, Yamanishi K, Maki M, Hitomi K
The FEBS journal 275(22) 5667-5677 Nov 2008 [Refereed]
Miyata A, Natsuaki M, Yamanishi K
Experimental dermatology 17 843-848 Oct 2008 [Refereed]
Tsuda T, Ishikawa C, Nakagawa N, Konishi H, Tarutani M, Matsuki M, Yamanishi K
The British journal of dermatology 159 730-732 Sep 2008 [Refereed]
Nakagawa N, Tsuda T, Yamamoto M, Ito T, Futani H, Yamanishi K
The Journal of dermatology 35(7) 462-467 Jul 2008 [Refereed]
Tsuda T, Ishikawa C, Konishi H, Hayashi Y, Nakagawa N, Matsuki M, Mizutani H, Yamanishi K
Antimicrobial agents and chemotherapy 52 1538-1541 Apr 2008 [Refereed]
Tsujimura A, Matsuki M, Takao K, Yamanishi K, Miyakawa T, Hashimoto-Gotoh T
Frontiers in behavioral neuroscience 2 4 2008 [Refereed]
Minami S, Nakagawa N, Ito T, Sadanobu N, Lin Y, Natsuaki M, Yamanishi K
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 33 1280-1282 Oct 2007 [Refereed]
Human mast cell chymase cleaves pro-IL-18 and generates a novel and biologically active IL-18 fragment.
Omoto Y, Tokime K, Yamanaka K, Habe K, Morioka T, Kurokawa I, Tsutsui H, Yamanishi K, Nakanishi K, Mizutani H
Journal of immunology (Baltimore, Md. : 1950) 177 8315-8319 Dec 2006 [Refereed]
Terada M, Tsutsui H, Imai Y, Yasuda K, Mizutani H, Yamanishi K, Kubo M, Matsui K, Sano H, Nakanishi K
Proceedings of the National Academy of Sciences of the United States of America 103(23) 8816-8821 Jun 2006 [Refereed]
Minami S, Sadanobu N, Ito T, Natsuaki M, Yamanishi K
The Journal of dermatology 33(4) 256-259 Apr 2006 [Refereed]
Matsuno K, Yamada H, Iwata K, Jin D, Katsuyama M, Matsuki M, Takai S, Yamanishi K, Miyazaki M, Matsubara H, Yabe-Nishimura C
Circulation 112 2677-2685 Oct 2005 [Refereed]
The expression of p63 during epidermal remodeling in psoriasis.
Shen CS, Tsuda T, Fushiki S, Mizutani H, Yamanishi K
The Journal of dermatology 32 236-242 Apr 2005 [Refereed]
Apoptosis in the epidermis.
Yamanishi K, Shen CS, Mizutani H
Methods in molecular biology (Clifton, N.J.) 289 171-174 2005 [Refereed]
Drug eruption caused by azathioprine: value of using the drug-induced lymphocytes stimulation test for diagnosis.
Mori H, Yamanaka K, Kaketa M, Tamada K, Hakamada A, Isoda K, Yamanishi K, Mizutani H
The Journal of dermatology 31 731-736 Sep 2004 [Refereed]
A case of a large dermatofibrosarcoma protuberans successfully treated with radiofrequency ablation and transcatheter arterial embolization.
Imai Y, Habe K, Imada M, Hakamada A, Isoda KI, Yamanishi K, Uchida A, Mizutani H
The Journal of dermatology 31 42-46 Jan 2004 [Refereed]
Imai Y, Isoda K, Ito E, Hakamada A, Yamanishi K, Mizutani H
The Journal of dermatology 30 683-688 Sep 2003 [Refereed]
Daimon Y, Yamanishi K, Murakami Y, Kirishima T, Ito Y, Minami M, Okanoue T
Hepatology research : the official journal of the Japan Society of Hepatology 25(3) 281-286 Mar 2003 [Refereed]
Kuramoto N, Takizawa T, Takizawa T, Matsuki M, Morioka H, Robinson JM, Yamanishi K
The Journal of clinical investigation 109 243-250 Jan 2002 [Refereed]
Elevated expression of transglutaminase 1 and keratinization-related proteins in conjunctiva in severe ocular surface disease.
Nakamura T, Nishida K, Dota A, Matsuki M, Yamanishi K, Kinoshita S
Investigative ophthalmology & visual science 42 549-556 Mar 2001 [Refereed]
Inada R, Matsuki M, Yamada K, Morishima Y, Shen SC, Kuramoto N, Yasuno H, Takahashi K, Miyachi Y, Yamanishi K
The American journal of pathology 157 1875-1882 Dec 2000 [Refereed]
Hiiragi T, Sasaki H, Nagafuchi A, Sabe H, Shen SC, Matsuki M, Yamanishi K, Tsukita S
The Journal of biological chemistry 274(48) 34148-34154 Nov 1999 [Refereed]
Nishida K, Yamanishi K, Yamada K, Dota A, Kawasaki S, Quantock AJ, Kinoshita S
The American journal of pathology 154 331-336 Feb 1999 [Refereed]
Matsuki M, Yamashita F, Ishida-Yamamoto A, Yamada K, Kinoshita C, Fushiki S, Ueda E, Morishima Y, Tabata K, Yasuno H, Hashida M, Iizuka H, Ikawa M, Okabe M, Kondoh G, Kinoshita T, Takeda J, Yamanishi K
Proceedings of the National Academy of Sciences of the United States of America 95(3) 1044-1049 Feb 1998 [Refereed]
Activation of the human transglutaminase 1 promoter in transgenic mice: terminal differentiation-specific expression of the TGM1-lacZ transgene in keratinized stratified squamous epithelia.
Yamada K, Matsuki M, Morishima Y, Ueda E, Tabata K, Yasuno H, Suzuki M, Yamanishi K
Human molecular genetics 6 2223-2231 Dec 1997 [Refereed]
Ueda E, Ohno S, Kuroki T, Livneh E, Yamada K, Yamanishi K, Yasuno H
The Journal of biological chemistry 271(16) 9790-9794 Apr 1996 [Refereed]
Epidermolysis bullosa simplex (Weber-Cockayne) associated with a novel missense mutation of Asp328 to Val in Linker 12 domain of keratin 5.
Matsuki M, Hashimoto K, Yoshikawa K, Yasuno H, Yamanishi K
Human molecular genetics 4 1999-2000 Oct 1995 [Refereed]
Morishima Y, Ariyama T, Yamanishi K, Abe T, Ueda E, Yasuno H, Inazawa J
Genomics 28(2) 273-279 Jul 1995 [Refereed]
Transcriptional regulation of human transglutaminase1 gene by signaling systems of protein kinase C, RAR/RXR and Jun/Fos in keratinocytes.
Yamada K, Yamanishi K, Kakizuka A, Kibe Y, Doi H, Yasuno H
Biochemistry and molecular biology international 34 827-836 Oct 1994 [Refereed]
Konishi K, Morishima Y, Ueda E, Kibe Y, Nonomura K, Yamanishi K, Yasuno H
Biochemical and biophysical research communications 202(2) 976-983 Jul 1994 [Refereed]
Up-regulation of elafin/SKALP gene expression in psoriatic epidermis.
Nonomura K, Yamanishi K, Yasuno H, Nara K, Hirose S
The Journal of investigative dermatology 103 88-91 Jul 1994 [Refereed]
A novel mutation of Leu122 to Phe at a highly conserved hydrophobic residue in the helix initiation motif of keratin 14 in epidermolysis bullosa simplex.
Yamanishi K, Matsuki M, Konishi K, Yasuno H
Human molecular genetics 3 1171-1172 Jul 1994 [Refereed]
Analysis of p53 gene mutations and loss of heterozygosity for loci on chromosome 9q in basal cell carcinoma.
Konishi K, Yamanishi K, Ishizaki K, Yamada K, Kishimoto S, Yasuno H
Cancer letters 79 67-72 Apr 1994 [Refereed]
Localization of transglutaminase 1 mRNA in normal and psoriatic epidermis by non-radioactive in situ hybridization.
Nonomura K, Yamanishi K, Hosokawa Y, Doi H, Hirano J, Fukushima S, Yasuno H
The British journal of dermatology 128 23-28 Jan 1993 [Refereed]
Structure of the gene for human transglutaminase 1.
Yamanishi K, Inazawa J, Liew FM, Nonomura K, Ariyama T, Yasuno H, Abe T, Doi H, Hirano J, Fukushima S
The Journal of biological chemistry 267 17858-17863 Sep 1992 [Refereed]
Nosaka K, Yamanishi K, Nishimura H, Iwashima A
FEBS letters 305(3) 244-248 Jul 1992 [Refereed]
Low incidence of Ha-ras oncogene mutations in human epidermal tumors.
Lieu FM, Yamanishi K, Konishi K, Kishimoto S, Yasuno H
Cancer letters 59 231-235 Sep 1991 [Refereed]
Yamanishi K, Liew FM, Konishi K, Yasuno H, Doi H, Hirano J, Fukushima S
Biochemical and biophysical research communications 175(3) 906-913 Mar 1991 [Refereed]
Differential detection of human papillomavirus DNA type 6 and 11 amplified by polymerase chain reaction.
Liew FM, Yamanishi K, Kishimoto S, Yasuno H
Journal of dermatological science 1 369-372 Sep 1990 [Refereed]
Fujita T, Shibuya H, Hotta H, Yamanishi K, Taniguchi T
Cell 49(3) 357-367 May 1987 [Refereed]
Fujita T, Shibuya H, Ohashi T, Yamanishi K, Taniguchi T
Cell 46(3) 401-407 Aug 1986 [Refereed]
Yamanishi K, Iwashima A
Journal of cellular physiology 123(2) 235-240 May 1985 [Refereed]
Role of polyamine synthesis in the stimulation of hexose transport by epidermal growth factor and 12-O-tetradecanoylphorbol-13-acetate in cultured mouse fibroblasts.
Yamanishi K, Oku T, Iwashima A
Cell biology international reports 8 636 Aug 1984 [Refereed]
Yamanishi K, Hasegawa T, Iwashima A
FEBS letters 174(1) 71-75 Aug 1984 [Refereed]
Yamanishi K, Nishino H, Iwashima A
Biochemical and biophysical research communications 117(2) 637-642 Dec 1983 [Refereed]
Yamanishi K, Nishino H, Iwashima A
Experientia 39(9) 1036-1037 Sep 1983 [Refereed]
Misc
下腿潰瘍に対する圧迫療法のすすめ
伊藤 孝明, 中川 登, 永井 諒, 草壁 みのり, 和田 吉弘, 林 秀樹, 藤本 真由, 夏秋 優, 山西 清文
日本皮膚外科学会誌 22(2別冊) 208-208 Aug 2018
足底の潰瘍で初発した原発性皮膚未分化大細胞リンパ腫の1例
尼木 麻実, 今井 康友, 永井 諒, 山西 清文
日本皮膚悪性腫瘍学会学術大会プログラム・抄録集 34回 134-134 Jun 2018
新生児にみられる紅皮症
山西 清文
日本皮膚科学会雑誌 128(5) 1019-1019 May 2018
乾癬様皮疹を伴ったNFKB2遺伝子変異による分類不能型免疫不全症の1例
永井 諒, 今井 康友, 山西 清文
日本皮膚科学会雑誌 128(5) 1182-1182 May 2018
光パッチテストが診断に有用であったピルフェニドンによる光線過敏型薬疹の1例
草壁 みのり, 今井 康友, 夏秋 優, 山西 清文
アレルギー 67(4-5) 687-687 May 2018
タクロリムスは2型自然リンパ球が産生するTh2サイトカインの産生を抑制する
細谷 友雅, 今井 康友, 石川 裕人, 安田 好文, 永井 諒, 實川 織江, 中西 憲司, 善本 知広, 山西 清文, 五味 文
日本眼科学会雑誌 122(臨増) 254-254 Mar 2018
魚鱗癬皮膚における自然免疫系分子の活性化
山西 清文, 今井 康友, 羽田 孝司, 内山 良介
角化症研究会記録集 32 8-12 Mar 2018
リパスジル塩酸塩水和物による接触皮膚炎の1例
草壁 みのり, 今井 康友, 夏秋 優, 山西 清文
日本皮膚科学会雑誌 128(2) 243-243 Feb 2018
抗VII型コラーゲン抗体の測定が診断と病勢評価に有用であった後天性表皮水疱症の1例
和田 吉弘, 今井 康友, 山本 雅章, 山西 清文
西日本皮膚科 79(5) 511-511 Oct 2017
マムシ咬傷後に生じた片側性Beau's linesの1例
草壁 みのり, 今井 康友, 永井 諒, 山西 清文
皮膚の科学 16(4) 274-275 Aug 2017
鷲尾健, 福永淳, 寺井美奈子, 錦織千佳子, 人見清隆, 山西清文
角化症研究会記録集 28th 23-26 Mar 2014
小宮根真弓, 馬渕智生, 小澤明, 青山裕美, 岩月啓氏, 秋山真志, 池田志斈, 黒沢美智子, 金蔵拓郎, 佐野栄紀, 武藤正彦, 山西清文, 照井正
日本皮膚科学会雑誌 124(2) 201 Feb 2014
小西朋子, 小西朋子, 黒川一郎, 桑水流健二, 芝岡美枝, 覚野綾子, 螺良愛郎, 山西清文
皮膚科の臨床 56(1) 106-109 Jan 2014
山西清文
週刊日本医事新報 (4676) 56-57 Dec 2013
安水真規子, 深井和吉, 鶴田大輔, 磯野員倫, 皆川京子, 羽田孝司, 山西清文, 阿部優子, 穂積豊, 鈴木民夫
皮膚の科学 12(5) 353 Oct 2013
山西清文
日本皮膚科学会雑誌 123(10) 1929-1934 Sep 2013
HANEDA TAKASHI, ITO TAKAAKI, YAMANISHI KIYOFUMI, FUKUMOTO TAKAYA
Skin Cancer 28(1) 24-28 Jun 2013
古川紗綾佳, 今井康友, 山西清文
皮膚の科学 12(3) 229 Jun 2013
真鍋蘭, 夏秋優, 山西清文, 指宿千恵子, 足立厚子
日本皮膚科学会雑誌 123(5) 991 Apr 2013
真鍋蘭, 山本雅章, 中川登, 伊藤孝明, 山西清文
日本皮膚科学会雑誌 123(4) 493-494 Apr 2013
山西清文
日本皮膚科学会雑誌 122(13) 3186-3188 Dec 2012
夏秋優, 吉見宣子, 山西清文
皮膚科の臨床 54(11) 1497-1501 Oct 2012
今井康友, 善本隆之, 中西憲司, 山西清文, 善本知広
アレルギー 61(9/10) 1527 Oct 2012
古川紗綾佳, 今井康友, 上田英一郎, 山西清文
皮膚科の臨床 54(10) 1337-1340 Oct 2012
FURUKAWA SAYAKA, NATSUAKI MASARU, YAMANISHI KIYOFUMI
皮膚の科学 11(5) 409-412 Oct 2012
TOMINAGA CHIHARU, NATSUAKI MASARU, YAMANISHI KIYOFUMI
皮膚の科学 11(4) 290-293 Aug 2012
富永春, 夏秋優, 山西清文
日本皮膚科学会雑誌 122(7) 1799 Jun 2012
吉見宣子, 山西清文, 黒川一郎, 覚野綾子, 螺良愛郎
日本皮膚科学会雑誌 122(7) 1802 Jun 2012
吉見宣子, 山西清文, 黒川一郎, 覚野綾子, 覚野綾子
日本皮膚科学会雑誌 122(7) 1807-1808 Jun 2012
山西清文
新薬と臨床 61(6) 1330-1336 Jun 2012
羽田孝司, 今井康友, 真鍋蘭, 伊藤孝明, 山西清文, 飯室正樹
皮膚の科学 11(3) 226-227 Jun 2012
覚道真理子, 岡本陽子, 岡本陽子, 山西清文, 西村実果, 谷澤隆邦, 細貝昇, 管原由恵, 三村博子, 仲田洋美, 久保秀司, 久保秀司, 玉置知子, 玉置知子
日本遺伝カウンセリング学会誌 33(2) 63 May 2012
石村直也, 今井康友, 真鍋蘭, 羽田孝司, 山西清文
日本皮膚科学会雑誌 122(4) 1203 Apr 2012
山西清文
日本皮膚科学会雑誌 122(4) 1023 Apr 2012
真鍋蘭, 夏秋優, 山西清文
皮膚の科学 11(2) 180 Apr 2012
山西清文, 山本雅章, 坂口祥子, 福永淳
角化症研究会記録集 26th 30-33 Mar 2012
羽田孝司, 石村直也, 今井康友, 伊藤孝明, 山西清文, 黒川一郎, 螺良愛郎
皮膚の科学 11(1) 105 Feb 2012
福田佳奈子, 足立厚子, 佐々木祥人, 一角直行, 西岡美南, 小猿恒志, 廣畑成也, 山西清文, 小川豊, 福本毅
皮膚脈管膠原病研究会抄録集 35th 22 2012
武藤正彦, 天谷雅行, 池田志斈, 石河晃, 岩月啓氏, 大塚藤男, 金田眞理, 亀岡洋祐, 清水宏, 下村裕, 新関寛徳, 錦織千佳子, 橋本隆, 日野田裕治, 山西清文
稀少難治性皮膚疾患に関する調査研究 平成23年度 総括・分担研究報告書 213-281 2012
照井正, 黒沢美智子, 岩月啓氏, 小澤明, 武藤正彦, 池田志斈, 小宮根真弓, 山西清文, 佐野栄紀, 金蔵拓郎, 馬淵智生
稀少難治性皮膚疾患に関する調査研究 平成23年度 総括・分担研究報告書 39-44 2012
伊藤孝明, 中川登, 石村直也, 山本雅章, 谷口怜子, 羽田孝司, 山西清文, 古川紗綾佳
日本フットケア学会雑誌 9(3) 71 2012
山西清文, 今井康友, 津田達也, 青地聖子, 岩月啓氏
稀少難治性皮膚疾患に関する調査研究 平成23年度 総括・分担研究報告書 115-117 2012
中川登, 伊藤孝明, 石村直也, 山本雅章, 谷口怜子, 羽田孝司, 山西清文, 古川紗綾佳
日本フットケア学会雑誌 9(3) 71 2012
富永千春, 今井康友, 山西清文, 黒川一郎
皮膚の科学 10(6) 530 Dec 2011
大桑久弥, 田村邦宣, 福岡和也, 柴田英輔, 金村晋吾, 神谷瞳, 本田実紀, 政近江利子, 大搗泰一郎, 前田理沙, 平山倫子, 寺田貴普, 岡田あすか, 村上亜紀, 山田秀哉, 田端千春, 中野孝司, 鳥井郁子, 西上隆之, 辻村亨, 夏秋優, 山西清文
肺癌 51(4) 297-298 Aug 2011
吉見宣子, 夏秋優, 山西清文
J Environ Dermatol Cutan Allergol 5(3) 288 Jul 2011
今井康友, 善本知広, 善本隆之, 中西憲司, 山西清文
J Environ Dermatol Cutan Allergol 5(3) 289 Jul 2011
上田英一郎, 中川登, 山西清文, 山下由紀子, 福井義一
西日本皮膚科 73(3) 318 Jun 2011
HANEDA TAKASHI, NATSUAKI MASARU, YAMANISHI KIYOFUMI
皮膚の科学 10(3) 199-202 Jun 2011
黄昌弘, 今井康友, 中川登, 上田英一郎, 伊藤孝明, 夏秋優, 山西清文
皮膚の科学 10(3) 238-239 Jun 2011
名波正義, 櫨木聡, 小瀧慶長, 蓮池由紀子, 倉賀野隆裕, 野々口博史, 中西健, 今井康友, 山西清文
日本アフェレシス学会雑誌 30(2) 173 May 2011
山西清文
日本皮膚科学会雑誌 121(5) 886 Apr 2011
山本雅章, 中川登, 羽田孝司, 古川紗綾佳, 武井怜子, 伊藤孝明, 山西清文, 宇野歩美
日本皮膚科学会雑誌 121(5) 921 Apr 2011
羽田孝司, 夏秋優, 山西清文
日本皮膚科学会雑誌 121(5) 916 Apr 2011
古川紗綾佳, 中川登, 羽田孝司, 伊藤孝明, 夏秋優, 山西清文
皮膚の科学 10(2) 190 Apr 2011
黄昌弘, 河野容子, 山本雅章, 上田英一郎, 山西清文
日本皮膚科学会雑誌 121(3) 568 Mar 2011
長岡悠美, 夏秋優, 中川登, 宮本園子, 山西清文
皮膚科の臨床 53(3) 536-537 Mar 2011
武井怜子, 今井康友, 東田千春, 中川登, 山西清文
Skin Cancer 25(3) 388-389 Feb 2011
長岡悠美, 今井康友, 津田達也, 夏秋優, 山西清文, 津田健吉
皮膚科の臨床 53(2) 273-276 Feb 2011
武藤正彦, 岩月啓氏, 石河晃, 清水宏, 池田志斈, 大塚藤男, 錦織千佳子, 金田眞理, 新関寛徳, 橋本隆, 天谷雅行, 亀岡洋祐, 山西清文
稀少難治性皮膚疾患に関する調査研究 平成22年度 総括・分担研究報告書 181-184 2011
真鍋蘭, 今井康友, 山西清文, 青地聖子, 岩月啓氏
日本乾癬学会学術大会 26th 157 2011
黒沢美智子, 池田志斈, 上原里程, 中村好一, 岩月啓氏, 大野貴司, 清水宏, 山本明美, 山西清文, 小宮根真弓, 青山裕美, 永井正規, 太田晶子, 稲葉裕
稀少難治性皮膚疾患に関する調査研究 平成22年度 総括・分担研究報告書 33-37 2011
黒沢美智子, 池田志斈, 上原里程, 中村好一, 岩月啓氏, 大野貴司, 清水宏, 山本明美, 山西清文, 小宮根真弓, 青山裕美, 川村孝, 永井正規, 太田晶子, 稲葉裕
特定疾患の疫学に関する研究 平成22年度 総括・分担研究報告書 186-197 2011
山西清文, 今井康友, 津田達也, 青地聖子, 岩月啓氏
稀少難治性皮膚疾患に関する調査研究 平成22年度 総括・分担研究報告書 105-107 2011
古川紗綾佳, 古川紗綾佳, 今井康友, 真鍋蘭, 山西清文
日本乾癬学会学術大会 26th 158 2011
今井康友, 今井康友, 山西清文, 中西憲司
Top Atopy 9(4) 36-42 Dec 2010
上田英一郎, 夏秋優, 山西清文, 岡崎剛, 山下由紀子, 福井義一
皮膚の科学 9(6) 580 Dec 2010
吉見宣子, 吉見宣子, 夏秋優, 山西清文
J Environ Dermatol Cutan Allergol 4(5) 394 Nov 2010
深井和吉, 大霜智子, 阿部優子, 穂積豊, 田中あけみ, 石井正光, 山西清文, 鈴木民夫
日本人類遺伝学会大会プログラム・抄録集 55th 215 Oct 2010
NISHIMURA AKIKO, NATSUAKI MASARU, YAMANISHI KIYOFUMI
皮膚の科学 9(5) 452-457 Oct 2010
NAGAOKA YUMI, NATSUAKI MASARU, YAMANISHI KIYOFUMI
皮膚の科学 9(5) 462-464 Oct 2010
TAKEI RYOKO, NATSUAKI MASARU, YAMANISHI KIYOFUMI
皮膚の科学 9(5) 458-461 Oct 2010
夏秋優, 吉見宣子, 山西清文
J Tradit Med 27(Supplement) 108 Aug 2010
河野容子, 夏秋優, 山西清文
皮膚の科学 9(4) 397 Aug 2010
今井康友, 水谷仁, 中西憲司, 山西清文
Vis Dermatol 9(8) 858-859 Jul 2010
宮本園子, 津田達也, 夏秋優, 山西清文
臨床皮膚科 64(8) 577-580 Jul 2010
山本麻未, 津田健吉, 末永浩一, 和田沙代子, 渡邊将平, 笠間周平, 高岡俊雄, 木村卓, 梶山幸司, 武田正中, 芳川浩男, 長岡悠美, 山西清文
臨床神経学 50(7) 498 Jul 2010
MIYAMOTO SONOKO, ITO TAKAAKI, NAKAGAWA NOBORU, YAMANISHI KIYOFUMI, KIMURA TETSUNORI
臨床皮膚科 64(7) 493-496 Jun 2010
羽田孝司, 津田達也, 今井康友, 中川登, 伊藤孝明, 夏秋優, 山西清文, 澤田暁宏
皮膚の科学 9(3) 298 Jun 2010
吉見宣子, 栗木安弘, 夏秋優, 山西清文
皮膚の科学 9(3) 304 Jun 2010
IKOMA AKIHIKO, FUKUOKA MIYUKI, MIYACHI YOSHIKI, SHIRAFUJI YOSHINORI, YAMASAKI OSAMU, IWATSUKI KEIJI, KARASHIMA TADASHI, MAEYAMA YASUHIKO, HASHIMOTO TAKASHI, TSUDA TATSUYA, YAMANISHI KIYOFUMI, KITABA SHUN, INUI SHIGEKI, KATAYAMA ICHIRO, TOKURA YOSHIKI
皮膚の科学 9(Suppl.14) 25-30 Jun 2010
TAMAKI KUNIHIKO, TAKIGAWA MASAHIRO, HASHIMOTO TAKASHI, YAMANISHI KIYOFUMI, KATAYAMA ICHIRO, IWATSUKI KEIJI
皮膚の科学 9(Suppl.14) 31-35 Jun 2010
TAKEI RYOKO, NAKAGAWA NOBORU, ITO TAKAAKI, YAMANISHI KIYOFUMI
Skin Cancer 25(1) 25-28 May 2010
東直人, 夏秋優, 山西清文, 岩崎剛, 岩崎剛, 森本麻衣, 西岡亜紀, 関口昌弘, 北野将康, 橋本尚明, 松井聖, 佐野統
アレルギー 59(3/4) 434 Apr 2010
宇野歩美, 中川登, 古川紗綾佳, 羽田孝司, 山本雅章, 上田英一郎, 伊藤孝明, 夏秋優, 山西清文, 福本隆也
皮膚の科学 9(2) 185 Apr 2010
YOSHIMI NOBUKO, NATSUAKI MASARU, TARUTANI MASAHITO, YAMANISHI KIYOFUMI
皮膚の科学 9(2) 132-136 Apr 2010
青地聖子, 辻和英, 阪口政清, 許南浩, 津田達也, 山西清文, 小宮根真弓, 岩月啓氏
日本皮膚科学会雑誌 120(3) 691 Mar 2010
山本雅章, 今井康友, 東田千春, 中川登, 山西清文
日本皮膚科学会雑誌 120(3) 744 Mar 2010
羽田孝司, 中川登, 武井怜子, 山本雅章, 伊藤孝明, 夏秋優, 山西清文
日本皮膚科学会雑誌 120(2) 266 Feb 2010
長岡悠美, 夏秋優, 山西清文
日本皮膚科学会雑誌 120(2) 259-260 Feb 2010
大霜智子, 深井和吉, 石井正光, 鈴木民夫, 阿部優子, 穂積豊, 横井俊明, 山西清文
日本皮膚科学会雑誌 120(2) 268 Feb 2010
武井怜子, 津田達也, 山西清文
臨床皮膚科 64(2) 117-120 Feb 2010
MURAKAMI MASAFUMI, RIN YOSHIAKI, TSUDA TATSUYA, YAMANISHI KIYOFUMI
皮膚の科学 9(Suppl.13) 24-29 Feb 2010
山西清文, 津田達也, 石川千香
稀少難治性皮膚疾患に関する調査研究 平成21年度 総括・分担研究報告書 80-82 2010
AZUMA NAOTO, NATSUAKI MASARU, YAMANISHI KIYOFUMI, KONDO NOBUYUKI, KONDO NOBUYUKI, IWASAKI TSUYOSHI, IWASAKI TSUYOSHI, MORIMOTO MAI, NISHIOKA AKI, SEKIGUCHI MASAHIRO, KITANO MASAYASU, HASHIMOTO NAOAKI, MATSUI KIYOSHI, SANO HAJIME
日本臨床免疫学会会誌 33(3) 149-153 2010
山西清文
稀少難治性皮膚疾患克服のための生体試料の収集に関する研究 平成21年度 総括・分担研究報告書 33-37 2010
古川紗綾佳, 今井康友, 上田英一郎, 山西清文
日本乾癬学会学術大会 25th 179 2010
池田志斈, 高木敦, 黒沢美智子, 山本明美, 小宮根真弓, 橋本隆, 清水宏, 山西清文, 武藤正彦
稀少難治性皮膚疾患克服のための生体試料の収集に関する研究 平成21年度 総括・分担研究報告書 23-27 2010
今井康友, 古川紗綾佳, 津田達也, 上田英一郎, 山西清文
皮膚の科学 8(6) 816 Dec 2009
武井怜子, 夏秋優, 山西清文
皮膚の科学 8(6) 810 Dec 2009
Works
Skin phenotype in FGF10 deficiency
1999 - 2000
Pathogenesis of ichthyosiform phenotype in transglutaminase 1 deficiency
1998 - 2001
Research Grants & Projects
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(若手研究(B))
Project Year: 2008 - 2010 Investigator(s): Noboru NAKAGAWA
An agonist peptide for protease-activated receptor 2 (PAR2) enhanced the IL-1ss- or TNF-α-induced production of CXCL8, which was markedly suppressed by tetracyclines in normal human epidermal keratinocytes (NHEK). The PAR2 agonist and IL-17 induce...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2008 - 2010 Investigator(s): Kiyofumi YAMANISHI
The protein cross-links in the stratum corneum include Gln-Lys and SS bonds. In the present study, in combination of the high resolution fluorescent imaging for in situ transglutaminase activity and SS bonds with immunofluorescence, we showed that...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2007 - 2008 Investigator(s): Hitomi KIYOTAKA
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2006 - 2007 Investigator(s): Kiyofumi YAMANISHI
MicroRNAs (miRNA) are functional RNAs that regulate gene expression in groups. Recently, miRNAs have been supposed to be involved in pathophysiology of a variety of diseases. In the present study, we have focused on the role of miRNAs in keratinoc...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2001 - 2003 Investigator(s): Kazuto NOSAKA
Thiamin-responsive megaloblastic anemia (TRMA ; OMIM 249270) is an autosomal recessive disorder defined by the occurrence of megaloblastic anemia, diabetes mellitus, sensorineural deafness, and responding to thiamin treatment. It has been speculat...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2001 - 2003 Investigator(s): Hitoshi MIZUTANI
We have established two transgenic mice (skin specifically caspase-1 and IL-18 overexpressed mice), and these mice developed persistent dermatitis similar to the human atopic dermatitis (AD). The skin and systemic immune systems of these mice were...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2001 - 2003 Investigator(s): Kiyofumi YAMANISHI
Netherton syndrome is characterized by ichthyosis, atopy, and trichorrhexis invasinata. The disease gene for the syndrome has been identified to be SPINK5 for a serine protease inhibitor. However, the molecular pathogenesis of the ichthyosis is st...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 1999 - 2001 Investigator(s): Kiyofumi YAMANISHI
Transglutaminase 1 knockout mice (TGase1^<-/->) showed immature stratum corneum which lacks the cornified envelopes (CE) with defective assembly of loricrin, a major precursor protein of CE. Severely damaged barrier function of TGase1^<-/-> skin w...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 1999 - 2000 Investigator(s): Kiyofumi YAMANISHI
Transglutaminase 1 (TGase 1) is a keratinization specific enzyme which catalyzes epsilon-(gamma-glutamyl) lysine cross-linking of substrate proteins to generate the cornified envelope at the cell periphery of the stratum corneum. We examined conju...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 1997 - 1998 Investigator(s): Kiyofumi YAMANISHI
We generated transgenic mice expressing the Escherichia coli beta-galactosidase gene (lalphaZ) directed by the 5' upstream region of human transglutaminase 1 (TGase 1) gene. beta-Galactosidase histochemistry revealed that the TGMI-lalphaZ transgen...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(一般研究(C))
Project Year: 1994 - 1995 Investigator(s): Kiyofumi YAMANISHI
Great progress is being made in the elucidation of disease genes, especially in hereditary skin diseases, by genome analysis, including functional and positional cloning. In more than 50 skin disorders, not only the chromosomal localizations, but ...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(一般研究(C))
Project Year: 1991 - 1992 Investigator(s): Hirokazu YASUNO
The deletion and mutation of tumor suppressor gene have been implicated to be an important step of carcinogenesis. In this study, we investigated these changes in tumor suppressor genes in skin cancer.The incidence of basal cell carcinoma (BCC) is...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(一般研究(C))
Project Year: 1989 - 1990 Investigator(s): Hirokazu YASUNO
The oncogenes and tumor suppressor genes have been suggested to be involved in tumorigenesis of human cell. In this project, on the basis of mechanisms of epidermal keratinocytes growth and its deregulation, we tried to detect the mutations of the...
Transglutaminase disorders
Cooperative Research
Molecular biology of keratinization disorders
Cooperative Research
Molecular pathophysiology of skin diseases
Cooperative Research
