筒井ひろ子 (Hiroko Tsutsui) - マイポータル

基本情報

所属: 兵庫医科大学医学部教授 (名誉教授)

学位: 博士(医学)(大阪市立大学)

連絡先: hi-tsutsuihyo-med.ac.jp
通称等の別名: ツツイ
J-GLOBAL ID: 200901074792652672
researchmap会員ID: 1000055954

研究キーワード

研究分野

経歴

2016年4月 - 現在

兵庫医科大学, 名誉教授
2006年1月 - 2015年3月

兵庫医科大学, 教授
2000年1月 - 2005年12月

兵庫医科大学, 助教授・准教授
1996年 - 2000年

兵庫医科大学講師
2000年

- 兵庫医科大学助教授
1991年 - 1996年

大阪市立大学医学部助手
1986年 - 1988年

Postdoctral Research Associate
at Yale University

学歴

- 1985年

大阪市立大学, 医学研究科
- 1981年

大阪市立大学, 医学部, 医学

委員歴

2008年 - 現在

日本細菌学会, 評議員
日本免疫学会評議員

論文

234

Carbon‐ion irradiation together with autophagy inhibition and immune checkpoint inhibitors protect against pancreatic cancer development in mouse model

Makoto Sudo, Yaoyao Wang, Jingren Wang, Koubun Yasuda, Keiko Mitani, Shuhei Hayashi, Masaki Ohmuraya, Hiroko Tsutsui, Jiro Fujimoto

Journal of Hepato-Biliary-Pancreatic Sciences 2025年4月14日
Autophagy Inhibition Increased Sensitivity of Pancreatic Cancer Cells to Carbon Ion Radiotherapy.

Makoto Sudo, Hiroko Tsutsui, Shuhei Hayashi, Koubun Yasuda, Keiko Mitani, Nana Iwami, Makoto Anzai, Toshiro Tsubouchi, Mitsuaki Ishida, Sohei Satoi …

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 57(4) 212-225 2023年7月19日
Antithrombin together with NETs inhibitor protected against Postoperative adhesion formation in mice

Makoto Sudo, Jinyang Xu, Keiko Mitani, Mayo Jimbo, Hiroko Tsutsui, Etsuro Hatano, Jiro Fujimoto

Cellular Physiology and Biochemistry 55(4) 400-412 2021年
Blockade of tumor necrosis factor by etanercept prevents postoperative adhesion formation in mice

Makoto Sudo, Kenjiro Iida, Hiroko Tsutsui, Keiko Mitani, Mayo Jimbo, Etsuro Hatano, Jiro Fujimoto

Cellular Physiology and Biochemistry 54(5) 1041-1053 2020年
Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation.

Naoki Uyama, Hiroko Tsutsui, Songtao Wu, Koubun Yasuda, Etsuro Hatano, Xian-Yang Qin, Soichi Kojima, Jiro Fujimoto

Scientific reports 9(1) 17558-17558 2019年11月26日
ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism

Rendong Fang, Ryosuke Uchiyama, Shunsuke Sakai, Hideki Hara, Hiroko Tsutsui, Takashi Suda, Masao Mitsuyama, Ikuo Kawamura, Kohsuke Tsuchiya

Mucosal Immunology 12(5) 1092-1103 2019年9月
The effect of Daikenchuto, Japanese herbal medicine, on adhesion formation induced by cecum cauterization and cecum abrasion in mice

Songtao Wu, Naoki Uyama, Rei Atono Itou, Etsuro Hatano, Hiroko Tsutsui, Jiro Fujimoto

Biological and Pharmaceutical Bulletin 42(2) 179-186 2019年
Immunohistochemical characterization of cancer-associated fibroblasts at the primary sites and in the metastatic lymph nodes of human intrahepatic cholangiocarcinoma.

Rei Atono Itou, Naoki Uyama, Seiichi Hirota, Norifumi Kawada, Songtao Wu, Seikan Miyashita, Ikuo Nakamura, Kazuhiro Suzumura, Hideaki Sueoka, Tosihiro Okada …

Human pathology 83 77-89 2019年1月
Caffeine-stimulated muscle IL-6 mediates alleviation of non-alcoholic fatty liver disease.

Fang C, Cai X, Hayashi S, Hao S, Sakiyama H, Wang X, Yang Q, Akira S, Nishiguchi S, Fujiwara N …

Biochim Biophys Acta Mol Cell Biol Lipids. 1864(3) 271-280 2018年12月査読有り
Pu'erh tea extract-mediated protection against hepatosteatosis and insulin resistance in mice with diet-induced obesity is associated with the induction of de novo lipogenesis in visceral adipose tissue

Xianbin Cai, Shuhei Hayashi, Chongye Fang, Shumei Hao, Xuanjun Wang, Shuhei Nishiguchi, Hiroko Tsutsui, Jun Sheng

JOURNAL OF GASTROENTEROLOGY 52(12) 1240-1251 2017年12月査読有り
Inflammasome and Fas-Mediated IL-1β Contributes to Th17/Th1 Cell Induction in Pathogenic Bacterial Infection In Vivo.

Uchiyama R, Yonehara S, Taniguchi S, Ishido S, Ishii KJ, Tsutsui H

Journal of immunology (Baltimore, Md. : 1950) 199(3) 1122-1130 2017年8月査読有り
Effect of Helicobacter pylori infection on the link between GLP-1 expression and motility of the gastrointestinal tract

Hirotsugu Eda, Hirokazu Fukui, Ryosuke Uchiyama, Yoshitaka Kitayama, Ken Hara, Mo Yang, Mio Kodani, Toshihiko Tomita, Tadayuki Oshima, Jiro Watari …

PLoS ONE 12(5) 2017年5月1日査読有り
Caspase-1 deficiency promotes high-fat diet-induced adipose tissue inflammation and the development of obesity

Hiroaki Kimura, Tadayoshi Karasawa, Fumitake Usui, Akira Kawashima, Yuka Endo, Motoi Kobayashi, Ai Sadatomo, Jun Nakamura, Yusaku Iwasaki, Toshihiko Yada …

American Journal of Physiology - Endocrinology and Metabolism 311(5) E881-E890 2016年11月1日査読有り
Pu-erh tea extract ameliorates high-fat diet-induced nonalcoholic steatohepatitis and insulin resistance by modulating hepatic IL-6/STAT3 signaling in mice

Xianbin Cai, Chongye Fang, Shuhei Hayashi, Shumei Hao, Mingming Zhao, Hiroko Tsutsui, Shuhei Nishiguchi, Jun Sheng

JOURNAL OF GASTROENTEROLOGY 51(8) 819-829 2016年8月査読有り
PAMPs受容体研究の最前線細菌感染におけるインフラマソーム構成蛋白の新たな防御的役割(PAMPs receptor update Inflammasome proteins and host protection against bacterial infections)

土屋晃介, 内山良介, 酒井俊祐, 原英樹, 筒井ひろ子, 河村伊久雄, 光山正雄

日本細菌学雑誌 70(1) 127-127 2015年2月
Inflammasome Activation by Mitochondrial Oxidative Stress in Macrophages Leads to the Development of Angiotensin II-Induced Aortic Aneurysm

Fumitake Usui, Koumei Shirasuna, Hiroaki Kimura, Kazuki Tatsumi, Akira Kawashima, Tadayoshi Karasawa, Koichi Yoshimura, Hiroki Aoki, Hiroko Tsutsui, Tetsuo Noda …

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 35(1) 127-136 2015年1月査読有り
Perivascular leukocyte clusters are essential for efficient activation of effector T cells in the skin

Natsuaki Yohei, Egawa Gyohei, Nakamizo Satoshi, Ono Sachiko, Hanakawa Sho, Okada Takaharu, Kusuba Nobuhiro, Otsuka Atsushi, Kitoh Akihiko, Honda Tetsuya …

NATURE IMMUNOLOGY 15(11) 1064-1069 2014年11月査読有り
Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages

Shiho Suzuki, Hitomi Mimuro, Minsoo Kim, Michinaga Ogawa, Hiroshi Ashida, Takahito Toyotome, Luigi Franchi, Masato Suzuki, Takahito Sanada, Toshihiko Suzuki …

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111(40) E4254-E4263 2014年10月査読有り
NLRP3 Regulates Neutrophil Functions and Contributes to Hepatic Ischemia-Reperfusion Injury Independently of Inflammasomes

Yoshiyuki Inoue, Koumei Shirasuna, Hiroaki Kimura, Fumitake Usui, Akira Kawashima, Tadayoshi Karasawa, Kenji Tago, Katsuya Dezaki, Satoshi Nishimura, Junji Sagara …

JOURNAL OF IMMUNOLOGY 192(9) 4342-4351 2014年5月査読有り
Pu-erh tea extract induces the degradation of FET family proteins involved in the pathogenesis of amyotrophic lateral sclerosis

Yang Yu, Shuhei Hayashi, Xianbin Cai, Chongye Fang, Wei Shi, Hiroko Tsutsui, Jun Sheng

BioMed Research International 2014 2014年査読有り