舩江良彦 (Yoshihiko Funae) - マイポータル - researchmap

基本情報

所属: 大阪市立大学大学院医学研究科基礎医科学専攻（老年医科学大講座）医学研究科教授

学位: 医学博士

J-GLOBAL ID: 200901077510140975
researchmap会員ID: 1000055994

研究キーワード

1

Drug Metabolism

研究分野

1

ライフサイエンス / 医化学 /

学歴

2

- 1965年

関西学院大学, 理学部, 化学科
- 1965年

関西学院大学

受賞

1

2002年

薬物動態学会学会賞

MISC

66

Inhibition of liver glutathione S-transferase placental form-positive foci development in the rat hepatocarcinogenesis by Porphyra tenera (Asakusa-nori)

T Ichihara, H Wanibuchi, T Taniyama, Y Okai, Y Yano, S Otani, S Imaoka, Y Funae, S Fukushima

CANCER LETTERS 141(1-2) 211-218 1999年7月
Cytochrome P450 isoforms responsible for the N-deethylation and cyclohexane-hydroxylation of NS-21

A Nakamura, T Hirota, A Morino, S Imaoka, Y Funae, Y Yamamoto, T Tasaki, M Masuda, A Kazusaka, S Fujita

XENOBIOTICA 29(3) 243-252 1999年3月
Hepatic cytochrome P450 is directly inactivated by nitric oxide, not by inflummatory cytokines, in the early phase of endotoxemia

J. Hepatolo 30(6) 1035-1044 1999年
Isoforms of cytochrome P450 on organic nitrate-derived nitric oxide releuse in human heart vessels.

FEBS Lett. 452(3) 165-169 1999年
Developmental changes in the catalytic activity and expression of CYP2D isoforms in the rats.

Drug Metab. Dispos. 27 188-192 1999年
Presence of a threshold for promoting effects of phenobarbital on diethylnitrosamine-induced hepatic foci in the rat

M Kitano, T Ichihara, T Matsuda, H Wanibuchi, S Tamano, A Hagiwara, S Imaoka, Y Funae, T Shirai, S Fukushima

CARCINOGENESIS 19(8) 1475-1480 1998年8月
A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502)

K Nunoya, T Yokoi, K Kimura, K Inoue, T Kodama, M Funayama, K Nagashima, Y Funae, C Green, M Kinoshita …

PHARMACOGENETICS 8(3) 239-249 1998年6月
Cloning and characterization of the CYP2D1-binding protein, retinol dehydrogenase

S Imaoka, J Wan, T Chow, T Hiroi, R Eyanagi, H Shigematsu, Y Funae

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 353(2) 331-336 1998年5月
Tissue distributions of CYP2D1, 2D2, 2D3 and 2D4 mRNA in rats detected by RT-PCR

T Hiroi, S Imaoka, T Chow, Y Funae

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1380(3) 305-312 1998年5月
Dopamine formation from tyramine by CYP2D6.

Bicochem. Biophys. Res. Commun. 249(3) 838-843 1998年
Strani Differences in CYP3A-mediated C-8 hydroxylation(1,3,7-trimethyluric acid formation)of caffeine in Wistar and Dark Agouti rats : Rapid metabolism of caffine in dibrisoquine poor metabolizer model rats.

Biochem. Pharmacol 55(9) 1405-1411 1998年
P450 isoforms in a murine a murine macrophage cell line, RAW2264.7, and changes in the levels of P450 isoforms by activation with LPS and INF-a

Biochem. Biophys. Acta 1385 101-106 1998年
Strain differences in CYP3A-mediated C-8 hydroxylation(1,3,7-trimethyluric acid formation)of caffeine in Wistar and Dark Agouti rats.

Biochem. Pharmacol. 55(9) 1405-1411 1998年
Evidence that immature rat liver is capable of participating in steroidogenesis by expressing 17 alpha-hydroxylase/17,20-lyase P450c17

M Katagiri, K Tatsuta, S Imaoka, Y Funae, K Honma, N Matsuo, H Yokoi, K Ishimura, F Ishibashi, N Kagawa

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 64(1-2) 121-128 1998年1月
Cis-diamminedichloroplatinum induces peroxisomes as well as CYP4A1 in rat kidney

M Nakamura, S Imaoka, E Tanaka, S Misawa, Y Funae

RESEARCH COMMUNICATIONS IN MOLECULAR PATHOLOGY AND PHARMACOLOGY 99(1) 23-32 1998年1月
Nicotine metabolism in liver microsomes from rats with acute hepatitis or cirrhosis

M Nakajima, K Iwata, T Yamamoto, Y Funae, T Yoshida, Y Kuroiwa

DRUG METABOLISM AND DISPOSITION 26(1) 36-41 1998年1月
Irreversible inhibition of cytochrome P450 by nitric oxide

Y Minamiyama, S Takemura, S Imaoka, Y Funae, Y Tanimoto, M Inoue

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 283(3) 1479-1485 1997年12月
Metabolism of epinastine, a histamine H1 receptor antagonist, in human liver microsomes in comparison with that of terfenadine

W Kishimoto, T Hiroi, K Sakai, Y Funae, T Igarashi

RESEARCH COMMUNICATIONS IN MOLECULAR PATHOLOGY AND PHARMACOLOGY 98(3) 273-292 1997年12月
Expression of four rat CYP2D isoforms in Saccharomyces cerevisiae and their catalytic specificity

J Wan, S Imaoka, T Chow, T Hiroi, Y Yabusaki, Y Funae

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 348(2) 383-390 1997年12月
A comparison of hepatic cytochrome P450 protein expression between infancy and postinfancy

T Tateishi, H Nakura, M Asoh, M Watanabe, M Tanaka, T Kumai, S Takashima, S Imaoka, Y Funae, Y Yabusaki …

LIFE SCIENCES 61(26) 2567-2574 1997年11月

もっとみる

書籍等出版物

3

Cytochrome P450 in rodents in Handbook of Experimental Pharmacology. Vol105 Cytochrome P450

Springer-Verlag Berlin Heiderberg 1993年
新生化学実験講座5 生体酸化・薬物代謝

東京化学同人 1992年
Multiple forms of cytochrome P-450 separable by high-performance liquid chromatography

Progress in HPLC, Vol. 1, Eds. H. Parvez, Y. Kato and S. Parvez, VNU Science Press, Utrecht, The Netherlands 1985年

所属学協会

5

共同研究・競争的資金等の研究課題

3