J-GLOBAL         Last updated: Mar 23, 2019 at 22:12
Health Sciences University of Hokkaido
School of Dentistry, Division of Oral Biology, Depertment of Pharmacology
Job title
Associate Professor

Research Interests


Research Areas


Academic & Professional Experience

Assistant Professor
Associate Professor
Higashi-Nippon Gakuen University, Research
National Institutes of Health, Visiting Fellow
Health Sciences University of Hokkaido,
National Institutes of Health, Guest Researcher
Health Sciences University of Hokkaid,


Graduate School, Division of Natural Science, Niigata University
Faculty of Science, Niigata University

Awards & Honors

Sep 2010
Lion, Japanese Association of Oral Biology

Published Papers

Nezu A, Morita T, Nagai T, Tanimura A
Experimental physiology   104(1) 61-69   Jan 2019   [Refereed]
InVivo imaging study for the regulation of salivary gland functions.
Impact, 2018:38-40 ,2018   2018 38-40   Apr 2018   [Invited]
Tanimura A, Nezu A, Morita T, Murata K
Folia pharmacologica Japonica   152(1) 21-27   2018   [Refereed][Invited]
Han JM, Tanimura A, Kirk V, Sneyd J
PLoS computational biology   13(2) 1-29   Feb 2017   [Refereed]
Sneyd J, Han JM, Wang L, Chen J, Yang X, Tanimura A, Sanderson MJ, Kirk V, Yule DI
Proceedings of the National Academy of Sciences of the United States of America   114(7) 1456-1461   Feb 2017   [Refereed]
Oura T, Murata K, Morita T, Nezu A, Arisawa M, Shuto S, Tanimura A
Chembiochem : a European journal of chemical biology   17(16) 1509-1512   Aug 2016   [Refereed]
Effect of 1,25-dihydroxyvitamin D3 on spontaneous calcium responses in rat dental epithelial SF2 cells revealed by long-term imaging.
Murata K, Takahashi A, Morita T, Nezu A, Fukumoto S, Saitoh M, Tanimura A.
Biomed Res 37: 329-334, 2016   37 329-334   2016   [Refereed]
Nezu A, Morita T, Tojyo Y, Nagai T, Tanimura A
Experimental physiology   100(6) 640-651   Jun 2015   [Refereed]
Development and application of fluorescent protein-based indicators for live cell imaging
Tanimura A
J Oral Biosci   57 54-60   2015   [Refereed][Invited]
Kunimoto R, Jimbow K, Tanimura A, Sato M, Horimoto K, Hayashi T, Hisahara S, Sugino T, Hirobe T, Yamashita T, Horio Y
The Journal of investigative dermatology   134(6) 1693-1700   Jun 2014   [Refereed]
Tojyo Y, Morita T, Nezu A, Tanimura A
Journal of pharmacological sciences   125(4) 340-346   2014   [Refereed]
Morita T, Nezu A, Tojyo Y, Tanimura A
Biochemical and biophysical research communications   439(4) 433-437   Oct 2013   [Refereed]
Tanimura A, Mochizuki T, Morita T, Nezu A, Tojyo Y, Arisawa M, Shuto S
Journal of biotechnology   167(3) 248-254   Sep 2013   [Refereed]
Tanimura A, Nezu A, Morita T
Nihon yakurigaku zasshi. Folia pharmacologica Japonica   141(5) 262-267   May 2013   [Refereed]
Tojyo Y, Morita T, Nezu A, Tanimura A
Cell calcium   53(5-6) 349-356   May 2013   [Refereed]
Morita T, Tanimura A, Shitara A, Suzuki Y, Nezu A, Takuma T, Tojyo Y
Archives of oral biology   56(11) 1356-1365   Nov 2011   [Refereed]
Nezu A, Tanimura A, Morita T, Tojyo Y
Journal of cell science   123(Pt 13) 2292-2298   Jul 2010   [Refereed]
[Use of fluorescent probes for the quantitative analysis of inositol 1, 4, 5-trisphosphate dynamics--calcium oscillations and IP3 dynamics].
Tanimura A
Seikagaku. The Journal of Japanese Biochemical Society   82(4) 309-314   Apr 2010   [Refereed]
Shitara A, Tanimura A, Sato A, Tojyo Y
American journal of physiology. Gastrointestinal and liver physiology   297(6) G1198-205   Dec 2009   [Refereed]
Morita, T., Tanimura, A., Baba, B., Kurosaki, T., and Tojyo, Y.
J. Cell Sci.   122(8) 1220-1228   Apr 2009   [Refereed]


蓑輪映里佳, 谷村明彦, 齊藤正人
北海道医療大学歯学雑誌   37(1) 55   Jun 2018
谷村明彦, 根津顕弘, 森田貴雄
日本薬理学雑誌   141(5) 262-267   May 2013
根津顕弘, 谷村明彦, 森田貴雄, 東城庸介
北海道医療大学歯学雑誌   28(1) 58-59   Jun 2009
谷村明彦, 東城庸介
日本薬理学雑誌   127(4) 249-255   Apr 2006
設楽彰子, 谷村明彦, 根津顕弘, 森田貴雄, 東城庸介
北海道医療大学歯学雑誌   24(1) 111-112   Jun 2005
設楽彰子, 谷村明彦, 根津顕弘, 森田貴雄, 東城庸介
東日本歯学雑誌   23(1) 61-67   Jun 2004
岡山三紀, 荒川俊哉, 谷村明彦, 溝口到, 田隈泰信
東日本歯学雑誌   23(1) 69-81   Jun 2004
口腔医学を基盤とした健康・長寿に関する先端的研究その1 研究成果最終報告書ならびに平成13-14年度研究成果報告書 文部科学省私立大学ハイテク・リサーチ・センター整備事業   61-62   2003
谷村明彦, 東城庸介
日本唾液腺学会誌   41 13-14   Nov 2000
根津顕弘, 谷村明彦, 東城庸介
東日本歯学雑誌   19(1) 15-22   Jun 2000
NaF-induced amylase release from rat parotid cells is mediated by PI breakdown leading to Ca2+ mobilization (共著)
American Journal of Physiology   260    1991
Relationship between cytosolic Ca2+ Concentration and amylase release in rat parotid acinar cells following muscarinic stimulation (共著)
Biochimica et Biophysica Acta   1134    1992
Origin of somatic cells in Bidder's organ and the gonad proper in the toad, ┣DBBufo(/)-┫DB ┣DBjaponicus(/)-┫DB ┣DBformosus(/)-┫DB (共著)
Zoological Science   9(2)    1992
Origin of somatic cells and Histogenesis in the primordial gonad of the Japanese tree frog ┣DBRhacophorus(/)-┫DB ┣DBarboreus(/)-┫DB. (共著)
Anatomy and Embryology   180(3)    1989
Proliferative activity of somatic cells during gonadal development in the Japanese pond frog, ┣DBRana(/)-┫DB ┣DBnigromaculata(/)-┫DB (共著)
Journal of Experimental Zoology   259(3)    1991
Ultrastructural Studies on the Development of Amphibian Gonad : Disproof of Witschi's Cortico-Medullary Antagonistic Theory (共著)
Sci. Rep. Niigata Univ. , Ser. D   30,1-23    1993
Evidence that Substance-P Receptors do not exist in mouse parotid and submandibular acinar cells (共著)
Archives of Oral Biology   38(3) 269-271   1993
Yosuke Tojyo, Akihiko Tanimura, Satoko Matsui, Yoshito Matsumoto
The Japanese Journal of Pharmacology   63(4) 439-446   1993
Yosuke Tojyo, Akihiko Tanimura, Yoshito Matsumoto
The Japanese Journal of Pharmacology   69(4) 381-389   1995
The Journal of Biological Chemistry   271(48) 30904-30908   1996
Inhibitory effect of extracellular ATP on the Ca2+ mobilization evoked by muscarinic stimulation in rat parotid acinar cells(共著)
Higashi Nippon Dental Journal   16(2) 199-204   1997
Determination of intracellular free chloride concentrations in rat parotid aeinar cells using the chloride-sensitive fluorescent indicator SPQ (共著)
Higashi Nippon Dental Journal   16(2) 271-278   1997
Effect of 5-hydroxytryptamine on intracellular calcium dynamics in cultured rat vascular smooth muscle cells (共著)
Research Communications in Molecular Pathology and Pharmacology   99(3) 305-319   1998
Polarized Ca2+ release in saponin-permeabilized parotid acinar cells evoked by flash photolysis of 'caged'inositol 1.4・5-trisphosphate (共著)
Biochemical Journal   332 769-772   1998
Analysis of Spatial and Temporal Characteristics of Ca2+ Release in Parmeabilized Parotid Cells
European Journal of Morphology   36(Supploment) 157-160   1998
Effect of Docosahexaenoic acid on intracellular calcium dynamics in vascular smoth muscle cells from normotensive and genetically hypertencive rats
Research Communications in Molecular Pathology and Pharmacology   102(1) 29-42   1998
Isoproterenol potentiates α-adrenergic and muscarinic receptor-mediated Ca2+ response in rat parotid cells
American Journal of Physiology.   276 C1282-C1287   1999
European Journal of Pharmacology.   380 163-170   1999
Isolation of rat submandibular ductal cells by Percoll Centrifugation
Higashi Nippon Dental Journal   19(1) 15-22   2000
Akihiro Nezu, Akihiko Tanimura, Yosuke Tojyo
Japanese Journal of Pharmacology   84(1) 25-31   2000
Mechanisms for calcium signaling and fluid and electrolytes secretion in salivary cells
Japanese Journal of Oral Biology   43, 343-352    2001
Tanimura, A., Shitara, A., Nezu, A., Morita, T., Tojyo, Y.
Cell Biol. Int.   27 1017-1023   2003

Books etc

The development of gonad(┣DBIn(/)-┫DB Biomechanism of gonad)

Conference Activities & Talks

Development of improved IP3 biosensors using circularly permuted fluorescent proteins
Azmeree Jahan, Kaori Murata, Takao Morita, Akihiro Nezu, Akihiko Tanimura.
16 Mar 2019   
蓑輪映里佳, 村田佳織, 倉重佳史, 齊藤正人, 谷村明彦
Sep 2018   
森田貴雄, 根津顕弘, 梨田智子, 谷村明彦
Sep 2018   
村田佳織, 森田貴雄, 根津顕弘, 齊藤正人, 谷村明彦
Sep 2018   
Role of the store-operated calcium entry on differentiation of dental epithelial cells.
Kaori Murata, Takao Morita, Akihiro Nezu, Masato Saitoh, Akihiko Tanimura.
WCP2018 KYOTO 18th world congress of basic and clinical pharmacology   Jul 2018   
Simultaneous monitoring of Ca2+ response and salivary secretion in rat submandibular gland in live animals. ,
Akihiro Nezu, Takao Morita, Akihiko Tanimura.
WCP2018 KYOTO 18th world congress of basic and clinical pharmacology   Jul 2018   
高橋亜友美, 村田佳織, 谷村明彦, 齊藤正人
小児歯科学雑誌   25 Apr 2017   
村田佳織, 森田貴雄, 高橋亜友美, 齊藤正人, 谷村明彦
Sep 2017   
谷村明彦, 根津顕弘, 森田貴雄
Sep 2017   
村田佳織, 森田貴雄, 齊藤正人, 谷村明彦
日本薬理学会北部会プログラム・抄録集   2017   
森田貴雄, 森田貴雄, 根津顕弘, 梨田智子, 谷村明彦
Journal of Oral Biosciences Supplement (Web)   2017   
森田貴雄, 根津顕弘, 谷村明彦
日本唾液腺学会誌   21 Nov 2016   
根津顕弘, 森田貴雄, 永井健治, 谷村明彦
日本唾液腺学会誌   21 Nov 2016   
渡邉瑞貴, 大浦泰, 森川優輝, 福田隼, 森田貴雄, 谷村明彦, 周東智
反応と合成の進歩シンポジウム講演要旨集   21 Oct 2016   
岩井美恵, 森田貴雄, 谷村明彦
北海道医療大学歯学雑誌   30 Jun 2016   
谷村明彦, 森田貴雄, 根津顕弘
北海道医療大学歯学雑誌   30 Jun 2016   


Inositol 1.4.5-trisphosphate Receptors on the plasma membrane
1998 - 1999
Development of FRET probes
2000 - 2001

Research Grants & Projects

Project Year: Apr 2018 - Mar 2019    Investigator(s): TANIMURA Akihiko
Project Year: Apr 2016 - Mar 2018    Investigator(s): TANIMURA Akihiko
Project Year: Apr 2016 - Mar 2017    Investigator(s): TANIMURA Akihiko
Project Year: Apr 2014 - Mar 2016    Investigator(s): TANIMURA Akihiko
Project Year: Apr 2011 - Mar 2015    Investigator(s): TANIMURA Akihiko