関崎春雄 (Haruo Sekizaki) - マイポータル - researchmap

基本情報

所属: 北海道医療大学薬学部薬学科生薬学教室教授

学位: 薬学博士(名城大学)

J-GLOBAL ID: 200901038603221155
researchmap会員ID: 1000060331

研究キーワード

4

研究分野

1

ライフサイエンス / 薬系化学、創薬科学 /

経歴

2

1997年 - 2003年

北海道大学兼任講師
1997年

- Hokkaido University, Assistant Professor

学歴

4

MISC

46

Identification of Armillaria nabsnona in gastrodia tubers

Biol. Pharm. Bull 31(7) 1410-1414 2008年
Trypsin-catalyzed synthesis of dipeptide containing α-aminoisobutylic acid using p- and m-(amidinomethyl)phenyl esters as acyl donor

Chem. Pharm. Bull 56(5) 688-691 2008年
Comparison of isoflavones among wild, black and yellow soybeans

Soybean Science 27 315-319 2008年
Application of several types of substrates to ficin-catalyzed peptide synthesis

Amino Acids 34 49-1531 2008年
A facile synthesis of p- and m-(amidinomethyl)phenyl esters derived from amono acid and tryptic hydrolysis of three synthetic inverse substrates

SEKIZAKI Haruo, ITOH Kunihiko, SHIBUYA Akiyoshi, TOYOTA Eiko, TANIZAWA Kazutaka

Chem. Pharm. Bull 55(10) 1514-1517 2007年
Kinetic properties of three isoforms of trypsin isolated from the pyloric caeca of chum salmon (Oncorhynchus keta);

Biol. Pharm. Bull 30(9) 1648-1652 2007年
Cultivation and preparation of Lithospermum roots quantification of total pigment in slender lateral roots

Haruo Sekizaki, Naotoshi Yoshida, Yoshio Hatakeyama, Sandra Naomi Asazu, Mizuho Yamamoto, Kiyoshi Horita, Yukari Noguchi

JOURNAL OF NATURAL MEDICINES 61(2) 217-219 2007年
Amidino-containing Schiff base copper (II) and Iron (III) chelates as a thrombin inhibitor

TOYOTA E, SEKIZAKI H, TAKAHASHI Y, ITOH K, TANIZAWA K

Chem. Pharm. Bull 53(1) 22-26 2005年
Photoregulation of deacylation rate of acyl trypsin derived from photoresponsive inverse substrate

Med. Chem. Lett. 13 3805-3808 2003年
Photoregulation of Deacylation Rate of Acyl Trypsin Derived From Photoresponsive Inverse Substrate

Bioorg. Med. Chem. Lett. 13(21) 3805-3808 2003年
Synthesis and Evaluation of Guanidine-Containing Shiff Base Copper(II), Zinc(II), Guanidine-Containing Shiff Base Copper(II), Zinc(II), and Iron(III) Chelates as Trypsin Inhibitors

Chem. Pharm. Bull. 51(6) 625-629 2003年
A facile synthesis of benzofuran derivatives: A useful synthon for preparation of trypsin inhibitor

H Sekizaki, K Itoh, E Toyota, K Tanizawa

HETEROCYCLES 59(1) 237-243 2003年1月
Crystal structure and nucleotide sequence of an anionic trypsin from chum salmon (Oncorhynchus keta) in comparison with Atlantic salmon (Salmo salar) and bovine trypsin

E Toyota, KKS Ng, S Kuninaga, H Sekizaki, K Itoh, K Tanizawa, MNG James

JOURNAL OF MOLECULAR BIOLOGY 324(3) 391-397 2002年11月
Trypsin-catalysed synthesis of oligopeptide amides: Comparison of catalytic efficiency among trypsins of different origin (bovine, Streptomyces griseus and chum salmon)

Haruo Sekizaki, Kunihiko Itoh, Eiko Toyota, Kazutaka Tanizawa

Journal of Peptide Science 8(9) 521-528 2002年9月
Trypsin-catalysed synthesis of oligopeptide amides: Comparison of catalytic efficiency among trypsins of different origin (bovine, Streptomyces griseus and chum salmon)

H Sekizaki, K Itoh, E Toyota, K Tanizawa

JOURNAL OF PEPTIDE SCIENCE 8(9) 521-528 2002年9月
Chum salmon trypsin-catalyzed preferential formation of peptides containing D-amino acid

H Sekizaki, K Itoh, E Toyota, K Tanizawa

AMINO ACIDS 21(2) 175-184 2001年
X-Ray Crystallographic Analyses of Complexes Between Bovine β-Trypsin and Schiff Base Copper((]G0002[))or Iron((]G0003[))Chelates.

J. Mol. Biol. 305(3) 471-479 2001年
Chum Salmon Trypsin-Catalyzed Peptide Synthesis with Inverse Substrate as Acyl Donor Component at Low Temperature.

J. Mol. Catal. B: Enzym. 11(1) 23-28 2000年
Anionic Trypsin from Chum Salmon : Activity with p-Amidinophenyl Ester and Comparison with Bovine and Streptomyces Griseus Trypsin.

Comp. Biochem. Physiol. B, 117 337-346 2000年
Trypsin-catalyzed peptide synthesis with m-guanidinophenyl and m-(guanidinomethyl)phenyl esters as acyl donor component

H Sekizaki, K Itoh, E Toyota, K Tanizawa

AMINO ACIDS 17(3) 285-291 1999年

もっとみる

書籍等出版物

5

現代医療における漢方薬

南江堂 2008年
新訂生薬学

南江堂 2007年
薬学生のための天然物化学

南江堂 2004年
エッセンシャル植物薬品化学

医歯薬出版 1993年
薬学生のための物理化学

廣広書店 1992年

所属学協会

3

共同研究・競争的資金等の研究課題

8