客本斉子 (Seiko Kyakumoto) - マイポータル

基本情報

所属: 岩手医科大学生化学講座・細胞情報科学分野研究員（２０１８現在）

学位: 歯学博士(岩手医科大学)

J-GLOBAL ID: 200901098686812918
researchmap会員ID: 1000061236

研究キーワード

研究分野

学歴

- 1978年

山形大学, 理学部, 化学科
- 1978年

山形大学

受賞

1996年

日本口腔組織培養研究会学術奨励賞
1995年

歯科基礎医学会賞
1995年

Award for Japanese Association for Oral Biology

論文

IL‑1β and TNF‑α suppress TGF‑β‑promoted NGF expression in periodontal ligament‑derived fibroblasts through inactivation of TGF‑β‑induced Smad2/3‑ and p38 MAPK‑mediated signals.

Ohta M, Chosa N, Kyakumoto S, Yokota S, Okubo N, Nemoto A, Kamo M, Joh S, Satoh K, Ishisaki A

International journal of molecular medicine 42(3) 1484-1494 2018年9月査読有り
Cell-cell interactions between monocytes/macrophages and synoviocyte-like cells promote inflammatory cell infiltration mediated by augmentation of MCP-1 production in temporomandibular joint

Miho Ibi, Sawa Horie, Seiko Kyakumoto, Naoyuki Chosa, Mariko Yoshida, Masaharu Kamo, Masato Ohtsuka, Akira Ishisaki

Bioscience Reports 38(2) 2018年3月29日査読有り
Water-soluble factors eluated from Surface pre-reacted glass-ionomer filler promote osteoblastic differentiation of human mesenchymal stem cells

Akira Nemoto, Naoyuki Chosa, Seiko Kyakumoto, Seiji Yokota, Masaharu Kamo, Mamoru Noda, Akira Ishisaki

Molecular Medicine Reports 17(3) 3448-3454 2018年3月1日査読有り
Bone marrow-derived mesenchymal stem cells propagate immunosuppressive/anti-inflammatory macrophages in cell-to-cell contact-independent and-dependent manners under hypoxic culture

Naoki Takizawa, Naoto Okubo, Masaharu Kamo, Naoyuki Chosa, Toshinari Mikami, Keita Suzuki, Seiji Yokota, Miho Ibi, Masato Ohtsuka, Masayuki Taira …

EXPERIMENTAL CELL RESEARCH 358(2) 411-420 2017年9月査読有り
ROCK/actin/MRTF signaling promotes the fibrogenic phenotype of fibroblast-like synoviocytes derived from the temporomandibular joint

Seiji Yokota, Naoyuki Chosa, Seiko Kyakumoto, Hitomichi Kimura, Miho Ibi, Masaharu Kamo, Kazuro Satoh, Akira Ishisaki

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 39(4) 799-808 2017年4月査読有り
Transforming growth factor-β1 suppresses bone morphogenetic protein-2-induced mesenchymal-epithelial transition in HSC-4 human oral squamous cell carcinoma cells via Smad1/5/9 pathway suppression.

Chiba T, Ishisaki A, Kyakumoto S, Shibata T, Yamada H, Kamo M

Oncology reports 37(2) 713-720 2017年2月査読有り
Zoledronic acid suppresses transforming growth factor-β-induced fibrogenesis by human gingival fibroblasts.

Komatsu Y, Ibi M, Chosa N, Kyakumoto S, Kamo M, Shibata T, Sugiyama Y, Ishisaki A

International journal of molecular medicine 38(1) 139-147 2016年7月査読有り
Transforming growth factor-β1 induces invasion ability of HSC-4 human oral squamous cell carcinoma cells through the Slug/Wnt-5b/MMP-10 signalling axis.

Hino M, Kamo M, Saito D, Kyakumoto S, Shibata T, Mizuki H, Ishisaki A

Journal of biochemistry 159(6) 631-640 2016年6月査読有り
Transforming growth factor-β1 induces epithelial-mesenchymal transition and integrin α3β1-mediated cell migration of HSC-4 human squamous cell carcinoma cells through Slug.

Saito D, Kyakumoto S, Chosa N, Ibi M, Takahashi N, Okubo N, Sawada S, Ishisaki A, Kamo M

Journal of biochemistry 153(3) 303-315 2013年3月査読有り
130

Transforming growth factor-beta 1 induces epithelial-mesenchymal transition and integrin alpha 3 beta 1-mediated cell migration of HSC-4 human squamous cell carcinoma cells through Slug

Daishi Saito, Seiko Kyakumoto, Naoyuki Chosa, Miho Ibi, Noriko Takahashi, Naoto Okubo, Shunsuke Sawada, Akira Ishisaki, Masaharu Kamo

JOURNAL OF BIOCHEMISTRY 153(3) 303-315 2013年3月
EGF Positively Regulates the Proliferation and Migration, and Negatively Regulates the Myofibroblast Differentiation of Periodontal Ligament-Derived Endothelial Progenitor Cells through MEK/ERK- and JNK-Dependent Signals

Hitomichi Kimura, Naoto Okubo, Naoyuki Chosa, Seiko Kyakumoto, Masaharu Kamo, Hiroyuki Miura, Akira Ishisaki

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY 32(4) 899-914 2013年査読有り
Fibroblast growth factor-1-induced ERK1/2 signaling reciprocally regulates proliferation and smooth muscle cell differentiation of ligament-derived endothelial progenitor cell-like cells

Mikako Takahashi, Naoto Okubo, Naoyuki Chosa, Noriko Takahashi, Miho Ibi, Masaharu Kamo, Harumi Mizuki, Akira Ishisaki, Seiko Kyakumoto

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 29(3) 357-364 2012年3月査読有り
166

Fibroblast growth factor-1-induced ERK1/2 signaling reciprocally regulates proliferation and smooth muscle cell differentiation of ligament-derived endothelial progenitor cell-like cells

Mikako Takahashi, Naoto Okubo, Naoyuki Chosa, Noriko Takahashi, Miho Ibi, Masaharu Kamo, Harumi Mizuki, Akira Ishisaki, Seiko Kyakumoto

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 29(3) 357-364 2012年3月
TGF-β-operated growth inhibition and translineage commitment into smooth muscle cells of periodontal ligament-derived endothelial progenitor cells through Smad- and p38 MAPK-dependent signals.

Yoshida M, Okubo N, Chosa N, Hasegawa T, Ibi M, Kamo M, Kyakumoto S, Ishisaki A

International journal of biological sciences 8(7) 1062-1074 2012年査読有り
TGF-beta-Operated Growth Inhibition and Translineage Commitment into Smooth Muscle Cells of Periodontal Ligament-Derived Endothelial Progenitor Cells through Smad- and p38 MAPK-Dependent Signals

Mariko Yoshida, Naoto Okubo, Naoyuki Chosa, Tomokazu Hasegawa, Miho Ibi, Masaharu Kamo, Seiko Kyakumoto, Akira Ishisaki

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES 8(7) 1062-1074 2012年
Mechanism of Fas-mediated cell death and its enhancement by TNF-alpha in human salivary gland adenocarcinoma cell line HSG

N Chosa, S Kyakumoto, N Kito, M Kamo, N Sato

EUROPEAN JOURNAL OF ORAL SCIENCES 112(4) 338-346 2004年8月査読有り
Expression of cAMP response element binding protein (CREB)-binding protein (CBP) and the implication in retinoic acid-inducible transcription activation in human salivary gland adenocarcinoma cell line HSG

S Kyakumoto, N Kito, N Sato

ENDOCRINE RESEARCH 29(3) 277-289 2003年査読有り
Cancer cells responsible for humoral hypercalcemia express mRNA encoding a secreted form of ODF/TRANCE that induces osteoclast formation

M Nagai, S Kyakumoto, N Sato

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 269(2) 532-536 2000年3月査読有り
Inhibition of retinoic acid-inducible transcription by COUP-TFI in human salivary gland adenocarcinoma cell line HSG

S Kyakumoto, M Ota, N Sato

BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE 77(6) 515-526 1999年査読有り
Isoform-specific monoclonal antibodies against HSP90

T Nemoto, R Roi, T Matsusaka, H Iwanari, H Yamashita, S Kyakumoto, N Sato

BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL 42(5) 881-889 1997年8月査読有り

もっとみる

MISC

Galectin-1 in human oral squamous cell calcinoma cells mediates suppression of anoikis.

Kamada, H, Kamo, M, Kyakumoto, S

Dent. J. Iwate Med. Univ. 32 157-169 2007年
ヒト顎下腺由来腺癌細胞株のプロテオミクス

加茂雅晴, 客本斉子, 佐藤詔子

日本口腔組織培養学会誌 15 11-28 2006年招待有り
Gene expression in human salivary gland cells on three-dimensional culture comprised in collagen sponge.

Minami, J, Kamo, M, Kyakumoto, S

Dent. J. Iwate Med. Univ. 30 216-227 2005年
Effects of the Medium Type, Serum Amount and Dexamethasone Induction on the Cell Proliferation and Alkaline Phosphatase Activity of Twice-passaged SD Rats' Bone Marrow Stromal Cells

TAIRA Masayuki, CHOSA Naoyuki, SAITOH Setsuo, SASAKI Kaori, SATO Nobuko, TAKAHASHI Junzo, ARAKI Yoshima

Journal of Oral Tissue Engineering 1(1) 59-68 2004年
Involvement of HSP90 in Anti-Fas-induced Apoptosis Signaling in the Human Salivary Gland Adenocarcinoma Cell Line HSG

鬼頭典子, 客本斉子, 帖佐直幸

Journal of Oral Biosciences 46 (3)229-242(3) 229-242 2004年
Mechanism of Fas-mediated cell death and its enhancement by TNF-a in human salivaly gland adenocarcinoma cell line HSG.

Eur. J. Oral Sci. 112 2004年
Expression of cAMP response element binding protein (CREB)-binding protein (CBP) and the implication in retinoic acid-inducible transcription activation in human salivary gland adenocarcinoma cell line HSG

S Kyakumoto, N Kito, N Sato

ENDOCRINE RESEARCH 29(3) 277-289 2003年
プロテオーム解析によるヒト顎下腺由来腺癌細胞株とその派生株における発現タンパク質の比較

口腔組織培養学会誌 9, 31-42 2000年招待有り
Cancer cells responsible for humoral hypercalcemia express mRNA encoding a secreted form of ODF/TRANCE that induces osteoblast formation. (jointly worked)

Biochem. Biophys. Res. Commun 269(2) 532-536 2000年
Comparative analysis of proteins from human salivary intercalated duct cell line and its derived cell line by proteomics.

Kamo, M, Kyakumoto, S, Chosa, N, Sato, N

The Japanese J of Tissue Culture Society for Dental Reserch 9(2) 31-42 2000年
ヒト顎下腺腺癌細胞株(HSG)におけるCREB結合タンパク(CBP)の発現とレチノイン酸レセプターによる転写活性化への関与

口腔細織培養学会誌 8(1) 25-35 1999年招待有り
Expression of CREB-binding protein(CBP) and implication in the ligand-induced transcription activation by retinoic acid receptors.

The Japanese Journal of Tissue Culture Society for Dental Research 8(1) 25-35 1999年
Inhibition of retinoic acid-inducible transcription by COUP-TFI in human salivary gland adenocarcinoma cell line HSG.

Biochem. Cell Biol. 77(6) 515-526 1999年
COUP-TFIによるレチノイン酸依存性転写活性化の抑制

口腔組織培養研究会誌 7(1) 63 1998年招待有り
Inhibition of retinoic acid-induced transcriptional activation by COUP-TFI.

The Japanese Journal of Tissue Culture Society for Dental Research 7(1) 63 1998年
ヒト顎下腺腺癌細胞株(HSG)における転写因子 COUP-TFの発現

口腔組織培養研究会誌 6(1) 75-76 1997年招待有り
Isoform-specific monoclonal antibodies against HSP90. (jointly worked)

Biochem. Mol. Biol. Int. 42(5) 881 1997年
Expression of retinoid X receptors and COUP-TFI in a human salivary adenocalcinoma cell line.

Biochem. Cell Biol. 75(6) 749-758 1997年
Expression of COUP-TF in human salivary gland adenocarcinoma cell line HSG.

Japanese Journal of Tissue culture society for Dental Research 6(1) 75-76 1997年
ヒト顎下腺由来腺癌細胞株における増殖と分化機構

日本ヒト細胞学会誌 9(1) 79-88 1996年招待有り

もっとみる

客本斉子

基本情報

研究キーワード

研究分野

学歴

受賞

論文

MISC

所属学協会

共同研究・競争的資金等の研究課題

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