OKA Atsuko

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Name
OKA Atsuko
Affiliation
Nippon Medical School
Degree
Ph.D.(The University of Tokyo), (BLANK)(Dokkyo Medical University)

Research Areas

 
 

Academic & Professional Experience

 
 
   
 
Nippon Medical School 
 
 
   
 
Professor, Nippon Medical School Department of Biology
 
1984
 - 
1992
Dokkyo University School of Medicine, Research Assistant
 
1992
 - 
1998
Dokkyo University School of Medicine, Lecturer
 
1998
 - 
2004
Dokkyo University School of Medicine, Associate
 

Education

 
 
 - 
1984
Graduate School, Division of Science, The University of Tokyo
 
 
 - 
1979
Faculty of Science, The University of Tokyo
 

Published Papers

 
Sakane Y, Iida M, Hasebe T, Fujii S, Buchholz DR, Ishizuya-Oka A, Yamamoto T, Suzuki KT
Biology open   7(1)    Jan 2018   [Refereed]
Ishizuya-Oka A
Molecular and cellular endocrinology   459 98-103   Dec 2017   [Refereed]
Ishizuya-Oka A
Cold Spring Harbor protocols   2017(10) pdb.prot097683   Oct 2017   [Refereed]
Hasebe T, Fujimoto K, Kajita M, Ishizuya-Oka A
Stem cells (Dayton, Ohio)   35(10) 2175-2183   Oct 2017   [Refereed]
Choi J, Ishizuya-Oka A, Buchholz DR
Endocrinology   158(6) 1623-1633   Jun 2017   [Refereed]
Hasebe T, Fujimoto K, Kajita M, Fu L, Shi YB, Ishizuya-Oka A
Stem cells (Dayton, Ohio)   35(4) 1028-1039   Apr 2017   [Refereed]
Hasebe, T., Fujimoto K., Kajita M., Ishizuya-Oka, A.
Cell Tissue Res.   365 309-318   2016   [Refereed]
Wen, L., Hasebe, T., Miller T.C., Ishizuya-Oka, A., Shi, Y.-B.
Cell Biosci.   5 e13   2015   [Refereed]
Fujii, J., Kodama, M., Oike, A., Matsuo, Y., Min, M.-S., Hasebe, T., Ishizuya-Oka, A., Kawakami, K., Nakamura, M.
PLoS One   9(5) e93655   2014   [Refereed]
Ishizuya-Oka, A., Hasebe, T.
Curr. Top. Dev. Biol.   103 305-327   2013   [Refereed][Invited]
Hasebe, T., Fu, L., Thomas C. Miller, T. C., Zhang, Y., Shi, Y.-B., Ishizuya-Oka., A.
Cell Biosci.   3 e18   2013   [Refereed]
Sun, G., Heimeier R. A., Fu, L., Hasebe, T., Das, B., Ishizuya-Oka, A., Shi, Y.-B.
Endocrinology   154(11) 4396-4407   2013   [Refereed]
Miller, T.C., Sun, G., Hasebe, T., Fu, L., Heimeier, R. A., Das, B., Ishizuya-Oka, A., Shi, Y.-B.
PLoS One   8(1) e55585   2013   [Refereed]
Hasebe, T., Kajita, M., Fu, L., Shi, Y.-B., Ishizuya-Oka, A.
Dev. Dyn.   241 403-414   2012   [Refereed]
Ishizuya-Oka, A., Shi, Y.-B.
Cell Biosci.   1 e30   2011   [Refereed][Invited]
Hasebe, T., Kajita, M., Iwabuchi, M., Ohsumi, K., Ishizuya-Oka, A.
Dev. Genes Evol.   211(4) 199-208   2011   [Refereed]
Motoi, N., Hasebe, T., Suzuki, KT, Ishizuya-Oka, A.
Cell Tissue Res.   344 445-453   2011   [Refereed]
Fujiwara, M., Hasebe, T, Kajita, M., Ishizuya-Oka, A., Ghazizadeh, M., Kawanami, O.
J. Vascular Res.   48 104-118   2011   [Refereed]
Shi Y.-B., Hasebe T., Fu L., Fujimoto K., Ishizuya-Oka, A.
Cell Biosci.   1 e30   2011   [Refereed]
Ishizuya-Oka, A.
Dev. Growth Differ.   53 202-212   2011   [Refereed][Invited]
Mathew S, Fu, L., Hasebe, T., Ishizuya-Oka, A. Shi, Y.-B.
Birth Defects Res. Part C   90 55-66   2010   [Refereed]
Ishizuya-Oka, A., Hasebe, T., Shi, Y.-B.
Apoptosis   15(3) 350-364   2010   [Refereed][Invited]
Hasebe, T., Buchholz, D.R., Shi, Y.-B., Ishizuya-Oka, A.
Stem Cells   29 154-161   2010   [Refereed]
Sun, G., Hasebe, T., Fujimoto K., Lu, R., Fu, L., Matsuda H., Kajita M., Ishizuya-Oka, A., Shi, Y.-B.
PLoS ONE   5(10) e13605   2010   [Refereed]
Ishizuya-Oka, A., Hasebe, T., Buchholz, D.R., Kajita, M., Fu, L., Shi, Y.-B.
FASEB J.   23 2568-2575   2009   [Refereed]
Ishizuya-Oka, A., Shi, Y.-B.
Mol. Cell. Endocrinol.   288 71-78   2008   [Refereed][Invited]
Ishizuya-Oka, A, Hasebe, T.
Digestion   77(suppl1) 42-47   2008   [Refereed][Invited]
Roles of matrix metalloproteinases and ECM remodeling during thyroid hormone-dependent intestinal metamorphosis in Xenopus laevis.
Fu, L., Hasebe, T, Ishizuya-Oka, A., Shi, Y.-B.
Organogenesis   3(1) 14-19   2007   [Refereed][Invited]
Ishizuya-Oka, A.
Dev. Growth Differ.   49 99-107   2007   [Refereed][Invited]
Ishizuya-Oka, A, Shi, Y.-B.
Dev. Dyn.   236 3358-3368   2007   [Refereed][Invited]
Shi, Y.-B., Fu, L., Hasebe, T., Ishizuya-Oka, A.
Pharmacol.& Therapeu.   116(3) 391-400   2007   [Refereed][Invited]
Ishizuya-Oka, A., Hasebe, T., Shimizu, K., Suzuki, K., Ueda, S.
Dev. Dyn.   235 3240-3249   2006   [Refereed]
Fu, L., Ishizuya-Oka, A., Buchholz, D.R., Amano, T., Shi, Y.-B.
J. Biol. Chem.   280 27856-27865   2005   [Refereed]
Ikuzawa, M., Shimizu, K., Yasumasu, S., Iuchi, I., Shi, Y.-B., Ishizuya-Oka, A.
Dev. Genes Evol.   216 109-118   2005   [Refereed]
Ishizuya-Oka, A.
J. Nippon Med. Sch.   72 13-18   2005   [Refereed][Invited]
Ishizuya-Oka, A., Shi, Y.-B.
Dev. Growth Differ.   47 601-607   2005   [Refereed][Invited]
Ishizuya-Oka, A., Shimizu, K., Sakakibara, S., Okano, H., Ueda, S.
J. Cell Sci.   116 3157-3164   2003   [Refereed]
Shimizu, K., Ishizuya-Oka, A., Amano, T., Yoshizato, K., Ueda, S.
Dev. Genes Evol.   212 357-364   2002   [Refereed]
Thyroid hormone-induced expression of Sonic hedgehog correlates with adult epithelial development during remodeling of the Xenopus stomach and intestine.
Ishizuya-Oka, A., Ueda S., Inokuchi, T., Amano, T., Damjanovski, S., Stolow, M., Shi, Y.-B.
Differentiation   69 27-37   2001   [Refereed]
Thyroid hormone regulation of apoptotic tissue remodeling : Implications from molecular analysis of amphibian metamorphosis.
Shi, Y.-B. Ishizuya-Oka, A.
Prog. Nucleic Acid Res. Mol. Biol.   65 53-100   2001   [Refereed][Invited]
Ishizuya-Oka, A., Ueda, S., Amano, T., Shimizu, K., Suzuki, K., Ueno, N., Yoshizato, K.
Cell Tissue Res.   303 187-195   2001   [Refereed]
Ishizuya-Oka, A., Ueda, S.
Acta Histochem. Cytochem.   33(3) 177-184   2000   [Refereed][Invited]
Sachs, L.M., Damjanovski, S., Jones, P.L., Li, Q., Amano T., Ueda, S., Shi, Y.-B., Ishizuya-Oka, A.
Comp. Biochem. Physiol. PartB   126 199-211   2000   [Refereed]
Ishizuya-Oka, A., Li, Q., Amano, T., Damjanovski, S., Ueda S., Shi, Y.-B.
J. Cell Biol.   150 1177-1188   2000   [Refereed]
Damjanovski S, Amano T, Li Q, Ueda S, Shi Y-B, Ishizuya-Oka, A.
Ann. New York Acad. Sci.   926 180-191   2000   [Refereed]
Ueda, S., Aikawa, M., Ishizuya-Oka, A., Yamaoka, S., Koibuchi, N., Yoshimoto, K.
Neuroscience   95(2) 389-398   2000   [Refereed]
Differential regulation of three thyroid hormone-responsive matrix metalloproteinase genes implicates distinct functions during frog embryogenesis.
Damjanovski, S., Puzianowska-Kuznicka M, Ishizuya-Oka, A., Shi, Y.-B.
FASEB J.   14 503-510   2000   [Refereed]
Hypothalamic aggression area under serotonergic control in mouse-killing behavior of rats.
Ueda, S., Ishizuya-Oka, A., Nishimura A., Takeuchi Y., Yoshimoto K.
Int. J. Neuropsychopharmacol.   2 255-261   1999   [Refereed]
Spatial and temporal regulation of collagenase-3, -4, and stromelysin-3 implications distinc functions in apoptosis and tissue remodeling during frog metamorphosis.
Damjanovski, S., Ishizuya-Oka, A., Shi, Y.-B.
Cell Res.   9 91-105   1999   [Refereed]
Ueda, S., Ishizuya-Oka, A., Nishimura, A., Takeuchi, Y., Yoshimoto, K.
Acta Histochem. Cytochem.   32 31-34   1999   [Refereed]
Thyroid hormone regulation of Xenopus laevis metamorphosis : Function of thyroid hormone receptors and roles of extracellclar matrix remodeling.
Shi, Y.-B., Sachs L. M., Jones P., Li Q., Ishizuya-Oka, A.
Wound Rep. Regen.   6 314-322   1998   [Refereed]
Regulation of apoptosis during development : Input from the extracellular matrix.
Shi, Y.-B., Li, Q., Damjanovski S, Amano, T., Ishizuya-Oka, A.
Int. J. Mol. Med.   2 273-282   1998   [Refereed]
Ishizuya-Oka, A., Inokuchi, T., Ueda, S.
Differentiation   63 59-68   1998   [Refereed]
Ueda, S., Aikawa M., Ishizuya-Oka, A., Koibuchi N., Yamaoka S., Yoshimoto, K.
Synapse   30 62-70   1998   [Refereed]
Gene regulation by thyroid hormone during amphibian metamorphosis : Implications on the role of cell-cell and cell-extracellular matrix interactions.
Stolow, M., Ishizuya-Oka, A., Su Y., and Shi, Y.-B.
Amer. Zool.   37 195-207   1997   [Refereed]
Shi, Y.-B., Ishizuya-Oka, A.
J. Biomed. Sci.   4 9-18   1997   [Refereed]
Ueda, S., Saitoh, Y., Koibuchi, N., Ishizuya-Oka, A.
Cell Tissue Res.   289 547-551   1997   [Refereed]
Ishizuya-Oka, A., Ueda, S., Damjanovski, S., Li, Q., Liang, V. C.-T., Shi, Y.-B.
Dev. Biol.   192 149-161   1997   [Refereed]
Ueda, S., Aikawa, M., Ishizuya-Oka, A., Nishimura, A., Kawata, M.
Neurosci. Lett.   211 97-100   1996   [Refereed]
Ishizuya-Oka, A., Ueda, S.
Cell Tissue Res.   286 467-476   1996   [Refereed]
Biphasic intestinal development in amphibians : Embryogenesis and remodeling during metamorphosis.
Shi, Y.-B., Ishizuya-Oka, A.
Curr. Top. Dev. Biol.   32 205-235   1996   [Refereed]
Ishizuya-Oka, A.
Microsc. Res. Tech.   34(3) 228-235   1996   [Refereed][Invited]
Ishizuya-Oka, A., Ueda, S., Shi, Y.-B.
Cell Tissue Res.   283 325-329   1996   [Refereed]
Ueda, S., Matsumoto, Y., Ishizuya-Oka, A., Aikawa, M., Nishimura, A., Kawata, M.
Brain Res. Bull.   39 89-99   1996   [Refereed]
Cell-specific and spatio-temporal expression of intestinal fatty acid-binding protein gene during amphibian metamorphosis.
Ishizuya-Oka, A., Shimozawa, A., Takeda, H., Shi, Y.-B.
Roux's Arch. Dev. Biol.   204 150-155   1994   [Refereed]
Inductive action of epithelium on differentiation of intestinal connective tissue of Xenopus laevis tadpoles during metamorphosis.
Ishizuya-Oka, A., Shimozawa, A.
Cell Tissue Res.   277 427-436   1994   [Refereed]
Demonstration of sucrase immunoreactivity of the brush border induced by duodenal mesenchyme in chick stomach endoderm.
Ishizuya-Oka, A., Mizuno, T.
Roux's Arch. Dev. Biol.   201 389-392   1992   [Refereed]
Programmed cell death and heterolysis of larval epithelial cells by macrophage-like cells in the anuran small intestine in vivo and in vitro.
Ishizuya-Oka, A., Shimozawa, A.
J. Morphol.   213(2) 185-195   1992   [Refereed]
Connective tissue is involved in adult epithelial metamorphosis in vitro.
Ishizuya-Oka, A., Shimozawa, A.
Roux's Arch. Dev. Biol.   201(5) 322-329   1992   [Refereed]
Induction of metamorphosis by thyroid hormone in anuran small interstine cultured organotypically in vitro.
Ishizuya-Oka, A., Shimozawa, A.
In Vitro Cell. Dev. Biol.   27A(11) 853-857   1991   [Refereed]
Changes in lectin-binding pattern in the digestive tract of Xenopus laevis during metamorphosis. I. Gastric region.
Ishizuya-Oka, A., Shimozawa, A.
J. Morphol.   205(1) 1-8   1990   [Refereed]
Changes in lectin-binding pattern in the digestive tract of Xenopus laevis during metamorphosis. II. Small intestine.
Ishizuya-Oka, A., Shimozawa, A.
J. Morphol.   205(1) 9-15   1990   [Refereed]
Ultrastructural changes in the connective tissue of the gastric region during the metamorphosis of Xenopus laevis.
Ishizuya-Oka, A., Shimozawa, A.
J. Morphol.   199(3) 259-268   1989   [Refereed]
Development of the connective tissue in the digestive tract of the larval and metamorphosing Xenopus laevis.
Ishizuya-Oka, A., Shimozawa, A.
Anat. Anz.   164(2) 81-93   1987   [Refereed]
Ultrastructural changes in the intestinal connective tissue of Xenopus laevis during metamorphosis.
Ishizuya-Oka, A., Shimozawa, A.
J. Morphol.   193(1) 13-22   1987   [Refereed]
Muscle fiber analysis in the mouse m. digastricus, m. stylohyoideus, m. zygomaticus and m. buccinator.
Ishizuya-Oka, A., Shimozawa, A.
Anat. Anz.   164(5) 355-361   1987   [Refereed]
Chronological analysis of the intestinalization of chick stomach endoderm Induced in vitro by duodenal mesenchyme.
Ishizuya-Oka, A., Mizuno, T.
Roux's Arch. Dev. Biol.   194 301-305   1985   [Refereed]
Intestinal cytodifferentiation in vitro of chick stomach endoderm Induced by the duodenal mesenchyme.
Ishizuya-Oka, A., Mizuno, T.
J. Embryol. Exp. Morphol.   82 163-176   1984   [Refereed]
Electron Microscopical Study of Self-Differentiation Potency in the Chick Embryonic Endoderm Cultured in Vitro
Ishizuya-Oka, A.
Roux's Arch. Dev. Biol.   192 171-178   1983   [Refereed]
Etude au microscope electronique de la differenciation in vitro de l'endoderme d'Intestin grele de jeune embryon d'oiseau, associe ou non a son mesenchyme.
Mizuno, T., Ishizuya, A.
Comp. Rend. Seanc. Soc. Biol.   176 580-584   1982   [Refereed]
Etude ultrastructurale de l'endoderme du tube digestif de l'embryon de poulet apres autodifferenciation in vitro.
Mizuno, T., Ishizuya, A.
Comp. Rend. Seanc. Soc. Biol.   176 889-893   1982   [Refereed]
Epithelial differentiation of the intestine of young quail embryos cultured organotypically in vitro.
Ishizuya, A.
J. Fac. Sci., Univ. Tokyo   IV(15) 71-79   1981
Electron microscopical study of the development of the quail intestinal epithelium.
Ishizuya, A.
J. Fac. Sci., Univ. Tokyo   IV(14) 335-344   1980

Books etc

 
Regulation of apoptosis by extracellular matrix during postembryonic development in Xenopus laevis. In When Cells Die II: A Comprehensive Evaluation of Apoptpsos and Programmed Cell Death. Lockshin, R.A., Zakeri, Z. (eds)
Ishizuya-Oka, A., Amano, T., Fu, L., Shi, Y.-B. (Part:Contributor, pp. 123-141)
John Wiley & Sons, Inc., New Jersey   2004   
Thyroid Hormone-Induced Apoptosis during Amphibian Metamorphosis. In Molecular Mechanisms of Programmed Cell Death. Shi, Y., Cidlowski, J. A., Scott, D.., Wu, J., Shi, Y.-B. (eds)
Amano, T., Fu, L., Ishizuya-Oka, A., Shi, Y.-B. (Part:Contributor, pp. 9-19)
Kluwer Academic/Plenum   2003   
Activation of matrix metalloproteinase genes during thyroid hormone-induced apoptotic tissue remodeling. In Programmed cell death. Shi, Y.-B., Shi, Y., Xu Y., Scott, D.W. (eds)
Shi, Y.-B., Ishizuya-Oka, A. (Part:Contributor, pp.13-26)
Plenum Press, New York   1997   

Works

 
Isolation of mesenchyme-specific genes in the remodeling intestine
1997

Research Grants & Projects

 
Remodeling of the digestive tract during amphibian metamorphosis