Sugai, Takeshi

J-GLOBAL         Last updated: May 29, 2019 at 04:13
 
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Name
Sugai, Takeshi
E-mail
sugaipha.keio.ac.jp
URL
http://www.pha.keio.ac.jp/laboratory/laboratory01.html
Affiliation
Keio University
Section
Faculty of Pharmacy Department of Pharmaceutical Sciences
Job title
Professor
Degree
農学 (The University of Tokyo)
Research funding number
60171120

Research Areas

 
 

Academic & Professional Experience

 
Apr 1984
 - 
Mar 1988
東京大学農学部文部教官助手
 
Apr 1988
 - 
Mar 1993
慶應義塾大学(理工学部)、助手
 
Aug 1991
 - 
Sep 1992
Research Associate, The Scripps Research Institute
 
Apr 1993
 - 
Mar 1997
慶應義塾大学(理工学部)、専任講師
 
Oct 1994
 - 
Mar 1995
茨城大学大学院(生物化学工学特別講義)、非常勤講師
 

Education

 
Mar 1981
   
 
農芸化学科, Faculty of Agriculture, The University of Tokyo
 
Mar 1983
   
 
農芸化学専門課程, Graduate School, Division of Agricultural Science, The University of Tokyo
 
Mar 1984
   
 
農芸化学専門課程, Graduate School, Division of Agricultural Science, The University of Tokyo
 

Committee Memberships

 
Jan 2003
 - 
Today
Current Organic Synthesis  Editorial Advisory Board
 
Jan 2003
 - 
Today
Mini-Reviews in Organic Chemistry  Editorial Advisory Board
 
Apr 2004
 - 
Today
日本化学会  化学教育協議会大学入試21WG委員
 
Mar 2001
 - 
Today
日本農芸化学会  日本農芸化学会誌編集幹事
 
Apr 1999
 - 
Today
日本糖質学会  評議員
 

Awards & Honors

 
Jun 2000
Enzymes in Large-scale Organic Synthesis, Presidential 2000 Green Chemistry Challenge Award, as a co-recipient of the honoring C.-H. Wong, Department of Environmental Protection, USA,
Winner: Takeshi Sugai
 
Apr 1994
生体触媒を利用する不斉合成と物質生産への応用, 農芸化学奨励賞, 日本農芸化学会
 

Published Papers

 
Chemoenzymatic Synthesis of Hydroxytyrosol Monoesters and Their Suppression Effect on Nitric Oxide Production Stimulated by Lipopolysaccharides
A. Sakakura, M. Pauze, A. Namiki, M. Funakoshi-Tago, H. Tamura, K. Hanaya, S. Higashibayashi, T. Sugai
Biosci. Biotechnol. Biochem.   83 185-191   Feb 2019   [Refereed]
Synthesis of 5-Hydroxy-3’,4’,7-trimethoxyflavone (HTMF) and Related Compounds and Elucidation of Their Reversal Effects on BCRP/ABCG2-Mediated Anticancer Drug Resistance
R. Tsunekawa, K. Katayama,. K. Hanaya, S. Higashibayashi, Y. Sugimoto, T. Sugai
ChemBioChem   20 210-220   Jan 2019   [Refereed]
Preparation of Menisdaurigenin and Related Compounds
R. Shirakawa, S. Ishikawa; M. Takahashi, Y. Ueno, Y. Uekusa, Y. Narukawa. T. Sugai, F. Kiuchi
J. Nat. Med.   73 236-243   Jan 2019   [Refereed]
Dearomative Oxidative Rearrangement of [3]Cyclo-1,8-carbazolylene
M. Yasui, H. Ohtsu, M. Kawano, K. Hanaya, T. Sugai, S. Higashibayashi
Chem. Lett.   47 1357-1359   Nov 2018   [Refereed]
Synthesis of Trilobatin from Naringin via Prunin as the Key Intermediate: Acidic Hydrolysis of the α-Rhamnosidic Linkage in Naringin under Improved Conditions
K. Kurahayashi, K. Hanaya, S. Higashibayashi, T. Sugai
Biosci. Biotechnol. Biochem.   82 1463-1467   Sep 2018   [Refereed]

Books etc

 
“Future Directions in Biocatalysis (Second Edition)”
R. Tsunekawa, K. Hanaya, M. Shoji, T. Sugai (Part:Joint Work, 279–295)
T. Matsuda, ed., Elsevier   Aug 2017   
“Comprehensive Organic Synthesis II (Second Edition) Volume 2: Additions to C–X Π-Bonds, Part 2”
T. Sugai, K. Fushuku (Part:Joint Work, 512–522)
P. Knochel, G. A. Molander, eds., Elsevier   Jan 2014   
Practical Methods for Biocatalysis and Biotransformations
T. Sugai, A. Fujino, H. Yamaguchi, M. Ikunaka (Part:Joint Work, 190-198)
J. Whittal, P. W. Sutton, eds., Wiley   Dec 2009   
Glycoscience: Chemistry and Chemical Biology
T. Sugai, T. Kajimoto (Part:Joint Work, 907-1021)
Springer-Verlag GmbH, Berlin Heidelberg New York (B. O. Fraser-Reid, K. Tatsuta, J. Thiem eds.)   Dec 2001   
単糖類の化学・酵素合成における最近の進歩について解説した。
Enzymes in Nonaqueous Solvents; Methods and Protocols, Methods in Biotechnology
Springer   Oct 2001   
界面バイオリアクターを用いる、微生物物質変換反応について著者らの成果を中心に解説した。

Conference Activities & Talks

 
New Entries for Transformation of Carbohydrates towards the Synthesis of Bioactive Compounds [Invited]
T. Sugai
2018 Frontiers in Chemical Biology   1 Aug 2018   
Enzyme-catalyzed Asymmetric Reduction of Cyclic Ketoesters and Application to Natural Product Synthesis [Invited]
T. Sugai, K. Kuwata, R. Tsunekawa, R. Fujita
The 13th Yonsei CBMH-Keio LCC Joint Symposium   13 Oct 2017   
The Complementary and Integrated Chemo-enzymatic Processes for Fine Chemical Syntheses (Invited Lecture) [Invited]
T. Sugai, Y. Yamashita, Y. Niitsu, M. Hamada, C. Hiraoka, T. Higashi, M. Shoji
The 14th Asia Pacific Confederation of Chemical Engineering   23 Feb 2012   
カルバ糖およびDHMEQを題材に、リパーゼによる位置および立体選択的変換について最新の成果を報告した。
Chemo-enzymatic approaches towards both enatiomers of dehydroxymethylepoxy-quinomicin (DHMEQ) (Selected Oral Presentation)
T. Sugai, C. Hiraoka, M. Hamada, Y. Niitsu, R. Kobayashi, K. Nakagawara, T. Seki, M. Suzuki, Y. Yamashita, T. Higashi, M. Shoji, K. Umezawa
10th International Symposium on Biocatalysis and Biotransformations   6 Oct 2011   
DHMEQを題材に、リパーゼによる位置および立体選択的変換について最新の成果を報告した。
Regio- and stereoselective lipase-catalyzed reactions on sugars and carbasugars (Invited Lecture) [Invited]
M. Hamada, Y. Ueda, N. Chishima, J. Calveras, T. Higashi, M. Shoji, T. Sugai
The International Chemical Congress of Pacific Basin Societies   19 Dec 2010   
glucal誘導体およびカルバ糖、さらにはDHMEQを題材に、リパーゼによる位置および立体選択的変換について最新の成果を報告した。

Research Grants & Projects

 
Efficient organic synthesis utilizing microbial enzyme catalysts
MEXT,JSPS: Grant-in-Aid for Scientific Research
Project Year: Apr 2014 - Mar 2017    Investigator(s): 須貝 威
Complementary and synergistic utilization of enzyme-catalyzed reactions and chemical transformation was studied, toward the efficient synthesis of complex target molecules involving valuable natural and unnatural products. The achievements are sh...

Social Contribution

 
化学情報協会
[]  Apr 2001 - Mar 2002