KUREBAYASHI Nagomi

J-GLOBAL         Last updated: Dec 27, 2019 at 13:51
 
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Name
KUREBAYASHI Nagomi
Affiliation
Juntendo University
Section
Faculty of Medicine
Job title
Associate professor
Degree
Dr. of Medicine(Juntendo University)

Research Areas

 

Academic & Professional Experience

 
1977
 - 
1992
Juntendo University, Research Assistant
 
1990
 - 
1991
University of Pennsylvania, Postdoctoral fellow
 
1992
 - 
2000
Juntendo University, Research Associate
 
2000
   
 
- Juntendo University, Assistant Professor
 

Education

 
 
 - 
1977
Faculty of Science, Ochanomizu University
 

Published Papers

 
Insights into channel modulation mechanism of RYR1 mutants using Ca2+ imaging and molecular dynamics
Yamazawa T, Ogawa H, Murayama T, Yamaguchi M, Oyamada H, Suzuki J, Kurebayashi N, Kanemaru K, Oguchi K, Sakurai T, Iino M
J Gen Physiol   152 in press   2020   [Refereed]
Assays for modulators of ryanodine receptor (RyR)/Ca2+ release channel activity for drug discovery for skeletal muscle and heart disease.
Murayama T, Kurebayashi N.
Current Protocols in Pharmacology   87 e71   Dec 2019   [Refereed]
Co-Phenotype of Left Ventricular Non-Compaction Cardiomyopathy and Atypical Catecholaminergic Polymorphic Ventricular Tachycardia in Association With R169Q
Nozaki Y, Kato Y, Uike K, Yamamura K, Kikuchi M, Yasuda M, Ohno S, Horie M, Murayama T, Kurebayashi N, Horigome H
Circ J   in press   Dec 2019   [Refereed]
Mori S, Iinuma H, Manaka N, Ishigami-Yuasa M, Murayama T, Nishijima Y, Sakurai A, Arai R, Kurebayashi N, Sakurai T, Kagechika H.
Eur J Med Chem   179 837-848   Oct 2019   [Refereed]
Eshima H, Tamura Y, Kakehi S, Nakamura K, Kurebayashi N, Murayama T, Kakigi R, Sakurai T, Kawamori R, Watada H.
J Appl Physiol   126 170-182   Jan 2019   [Refereed]
Uzu M, Nonaka M, Miyano K, Sato H, Kurebayashi N, Yanagihara K, Sakurai T, Hisaka A, Uezono Y.
J Pharmacol Sci   140 109-112   May 2019   [Refereed]
Murayama Takashi, Kurebayashi Nagomi, Ishigami-Yuasa Mari, Mori Shuichi, Suzuki Yukina, Akima Ryunosuke, Ogawa Haruo, Suzuki Junji, Kanemaru Kazunori, Oyamada Hideto, Kiuchi Yuji, Iino Masamitsu, Kagechika Hiroyuki, Sakurai Takashi
MOLECULAR PHARMACOLOGY   94(1) 722-730   Jul 2018   [Refereed]
Murayama T, Ogawa H, Kurebayashi N, Ohno S, Horie M, Sakurai T
Communications biology   1 98   Oct 2018   [Refereed]
Eshima Hiroaki, Tamura Yoshifumi, Kakehi Saori, Kurebayashi Nagomi, Murayama Takashi, Nakamura Kyoko, Kakigi Ryo, Okada Takao, Sakurai Takashi, Kawamori Ryuzo, Watada Hirotaka
PHYSIOLOGICAL REPORTS   5(7)    Apr 2017   [Refereed]
Uehara Akira, Murayama Takashi, Yasukochi Midori, Fill Michael, Horie Minoru, Okamoto Toru, Matsuura Yoshiharu, Uehara Kiyoko, Fujimoto Takahiro, Sakurai Takashi, Kurebayashi Nagomi
JOURNAL OF GENERAL PHYSIOLOGY   149(2) 199-218   Feb 2017   [Refereed]
Fujii Yusuke, Itoh Hideki, Ohno Seiko, Murayama Takashi, Kurebayashi Nagomi, Aoki Hisaaki, Blancard Malorie, Nakagawa Yoshihisa, Yamamoto Satoshi, Matsui Yumie, Ichikawa Mari, Sonoda Keiko, Ozawa Tomoya, Ohkubo Kimie, Watanabe Ichiro, Guicheney Pascale, Horie Minoru
HEART RHYTHM   14(1) 98-107   Jan 2017   [Refereed]
Fukunaga Ichiro, Fujimoto Ayumi, Hatakeyama Kaori, Aoki Toru, Nishikawa Atena, Noda Tetsuo, Minowa Osamu, Kurebayashi Nagomi, Ikeda Katsuhisa, Kamiya Kazusaku
STEM CELL REPORTS   7(6) 1023-1036   Dec 2016   [Refereed]
Hashimoto Muneaki, Doi Motomichi, Kurebayashi Nagomi, Furukawa Koji, Hirawake-Mogi Hiroko, Ohmiya Yoshihiro, Sakurai Takashi, Mita Toshihiro, Mikoshiba Katsuhiko, Nara Takeshi
FEBS OPEN BIO   6(12) 1178-1185   Dec 2016   [Refereed]
Murayama Takashi, Kurebayashi Nagomi, Ogawa Haruo, Yamazawa Toshiko, Oyamada Hideto, Suzuki Junji, Kanemaru Kazunori, Oguchi Katsuji, Iino Masamitsu, Sakurai Takashi
HUMAN MUTATION   37(11) 1231-1241   Nov 2016   [Refereed]
Hashimoto Muneaki, Nara Takeshi, Enomoto Masahiro, Kurebayashi Nagomi, Yoshida Mitsutaka, Sakurai Takashi, Mita Toshihiro, Mikoshiba Katsuhiko
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   466(3) 475-480   Oct 2015   [Refereed]
Murayama Takashi, Kurebayashi Nagomi, Yamazawa Toshiko, Oyamada Hideto, Suzuki Junji, Kanemaru Kazunori, Oguchi Katsuji, Iino Masamitsu, Sakurai Takashi
PLOS ONE   10(6)    Jun 2015   [Refereed]
Nonaka Miki, Morimoto Sachio, Murayama Takashi, Kurebayashi Nagomi, Li Lei, Wang Yuan-Yuan, Arioka Masaki, Yoshihara Tatsuya, Takahashi-Yanaga Fumi, Sasaguri Toshiyuki
BRITISH JOURNAL OF PHARMACOLOGY   172(9) 2369-2382   May 2015   [Refereed]
Odagiri Fuminori, Inoue Hana, Sugihara Masami, Suzuki Takeshi, Murayama Takashi, Shioya Takao, Konishi Masato, Nakazato Yuji, Daida Hiroyuki, Sakurai Takashi, Morimoto Sachio, Kurebayashi Nagomi
PLOS ONE   9(7)    Jul 2014   [Refereed]
Kamiya Kazusaku, Yum Sabrina W., Kurebayashi Nagomi, Muraki Miho, Ogawa Kana, Karasawa Keiko, Miwa Asuka, Guo Xueshui, Gotoh Satoru, Sugitani Yoshinobu, Yamanaka Hitomi, Ito-Kawashima Shioko, Iizuka Takashi, Sakurai Takashi, Noda Tetsuo, Minowa Osamu, Ikeda Katsuhisa
JOURNAL OF CLINICAL INVESTIGATION   124(4) 1598-1607   Apr 2014   [Refereed]
Hashimoto Muneaki, Enomoto Masahiro, Morales Jorge, Kurebayashi Nagomi, Sakurai Takashi, Hashimoto Tetsuo, Nara Takeshi, Mikoshiba Katsuhiko
MOLECULAR MICROBIOLOGY   87(6) 1133-1150   Mar 2013   [Refereed]

Conference Activities & Talks

 
Ryanodine receptor type 2 as a potential target for novel anti-arrhythmic drugs [Invited]
KUREBAYASHI Nagomi
The 71th Annual Meeting of the Korean Physiological Society   1 Nov 2019   
Mechanism and therapeutic strategies for arrhythmogenic diseases caused by RyR2 mutations
KUREBAYASHI Nagomi
9th FAOPS Congress   29 Mar 2019   
KUREBAYASHI Nagomi
18th World Congress of Basic and Clinical Pharmacology   5 Jul 2018   
Divergent effects of disease-linked mutations in RyR2 on Ca2+ dynamics in cardiac and non-cardiac cells. [Invited]
KUREBAYASHI Nagomi
29 Mar 2018   
Characteristics of Ca2+-induced Ca2+ release via RyR2s carrying various types of arrhythmogenic mutations. [Invited]
KUREBAYASHI Nagomi
International and Interdisciplinary Symposium   12 Jul 2016   

Misc

 
Discovery of novel RyR2 inhibitors as candidates for anti-arrhythmic drugs
KUREBAYASHI Nagomi
18th World Congress of Basic and Clinical Pharmacology (WCP2018, Kyoto)      Jul 2018
Impacts of loss-of-function RyR2 mutations on Ca2+ signaling in non-cardiac and cardiac cells
KUREBAYASHI Nagomi
18th World Congress of Basic and Clinical Pharmacology (WCP2018, Kyoto)      Jul 2018
Kyoto
Oxidative Stress-Responsive Apoptosis Inducing Protein(ORAIP) Mediates Cancer Cachexia-Induced Cardiac Injury
世古 義規, 野中 美希, 呉林 なごみ, 上園 保仁, 立石 健祐, 八尾 貴子
日本循環器学会学術集会抄録集   82回 OJ02-6   Mar 2018
Molecular Basis for Ca2+ Binding of RyR2 for Channel Activation and Diseases States
Murayama Takashi, Ogawa Haruo, Kurebayashi Nagomi, Sakurai Takashi
BIOPHYSICAL JOURNAL   114(3) 622A   Feb 2018
Therapeutic Effects of Ghrelin and Des-Acyl Ghrelin on Doxorubicin-Induced Cardiotoxicity
Nonaka Miki, Kurebayashi Nagomi, Murayama Takashi, Sugihara Masami, Hosoda Hiroshi, Kishida Shosei, Kangawa Kenji, Sakurai Takashi, Uezono Yasuhito
BIOPHYSICAL JOURNAL   114(3) 140A   Feb 2018
Relation between Voluntary Exercise Frequency and Cardiac Function in Dilated Cardiomyopathy Model Mice
Sugihara Masami, Kakigi Ryo, Murayama Takashi, Miida Takashi, Sakurai Takashi, Morimoto Sachio, Kurebayashi Nagomi
BIOPHYSICAL JOURNAL   114(3) 140A   Feb 2018
Regulation of Store Ca2+ Level in HEK293 Cells Expressing Type 2 Ryanodine Receptor (RyR2) with CPVT Mutations
Kurebayashi Nagomi, Murayama Takashi, Ohta Ryosaku, Yamashita Fumiyoshi, Suzuki Junji, Kanemaru Kazunori, Iino Masamitsu, Sakurai Takashi
BIOPHYSICAL JOURNAL   114(3) 117A   Feb 2018
Search for Type 2 Ryanodine Receptor Inhibitor by Monitoring Endoplasmic Reticulum Ca2+
Tamura Mai, Kurebayashi Nagomi, Murayama Takashi, Mori Shuichi, Ishigami-Yuasa Mari, Kagechika Hiroyuki, Suzuki Junji, Kanemaru Kazunori, Iino Masamitsu, Sakurai Takashi
BIOPHYSICAL JOURNAL   114(3) 116A   Feb 2018
High Throughput Screening of Type 2 Ryanodine Receptor Inhibitors by Monitoring Endoplasmic Reticulum Ca2+
KUREBAYASHI Nagomi
62nd Biophysical Society Annual Meeting, San Francisco      Feb 2018
Effects of CICR activity and expression levels of RyR2 on Ca2+ homeostasis in HEK293 cells
KUREBAYASHI Nagomi
20th International Symposium on Calcium Binding Protein and Calcium Function in Health and Disease (CaBP20), 淡路夢舞台国際会議場      Oct 2017

Research Grants & Projects

 
AMED: Practical Research Project for Rare/Intractable Diseases
Project Year: Apr 2017 - Mar 2020    Investigator(s): OHNO Seiko
Ministry of Education, Culture, Sports, Science and Technology: 基盤研究(B)
Project Year: 2016 - 2018    Investigator(s): 青沼 和隆
Ministry of Education, Culture, Sports, Science and Technology: 基盤研究(C)
Project Year: 2015 - 2017    Investigator(s): 呉林 なごみ
Ministry of Education, Culture, Sports, Science and Technology: 新学術領域研究(研究領域提案型)
Project Year: 2013 - 2014    Investigator(s): 呉林 なごみ
Ministry of Education, Culture, Sports, Science and Technology: 基盤研究(C)
Project Year: 2012 - 2014    Investigator(s): 村山 尚
Ministry of Education, Culture, Sports, Science and Technology: 基盤研究(C)
Project Year: 2012 - 2014    Investigator(s): 呉林 なごみ
Ministry of Education, Culture, Sports, Science and Technology: 基盤研究(A)
Project Year: 2011 - 2013    Investigator(s): 吉田 謙一
Ministry of Education, Culture, Sports, Science and Technology: 基盤研究(B)
Project Year: 2011 - 2013    Investigator(s): 森本 幸生
Ministry of Education, Culture, Sports, Science and Technology: 新学術領域研究(研究領域提案型)
Project Year: 2011 - 2012    Investigator(s): 呉林 なごみ
Ministry of Education, Culture, Sports, Science and Technology: 基盤研究(C)
Project Year: 2009 - 2011    Investigator(s): 村山 尚

Books etc

 
Ryanodine Receptors: Structure Function and Dysfunction in Clinical Disease.
Ogawa Y, and Murayama T & Kurebayashi N. (Part:Joint Work, Function of RyR3 homologues.)
Springer-Verlag US   2005   ISBN:978-0-387-23187-7
http://eknygos.lsmuni.lt/springer/412/131-140.pdf
Calcium releasing action of quercetin on sarcoplasmic reticulum from frog skeletal muscle.
"Structure and Function of Saroplasmic Reticulum" Academic Press,   1985