論文

査読有り
2013年1月

Mixed mucin-producing and squamous differentiated tumor of the uterine cervix: A report of a case as adenosquamous carcinoma in situ

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
  • Yoshiki Ohta
  • ,
  • Toshiaki Kunimura
  • ,
  • Mutsuko Omatsu
  • ,
  • Akira Shiokawa
  • ,
  • Miki Kushima
  • ,
  • Hidekazu Ota

39
1
開始ページ
420
終了ページ
423
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1111/j.1447-0756.2012.01904.x
出版者・発行元
WILEY-BLACKWELL

We report a non-invasive mixed mucin-producing and squamous differentiated tumor of the uterine cervix. This tumor was composed of two cell types: mucin-producing cells and non-mucin-producing cells. These cells were intimately mixed with each other, and showed intraepithelial spreading. The mucin-producing cells showed signet-ring or columnar shapes, and were localized to the lower-to-upper epithelial layer. The non-mucin-producing cells had eosinophilic cytoplasms with a monotonous appearance through the epithelium. Mitosis was sometimes observed in both cell types. Immunohistochemically, both cell types were positive for p16INK4A. The non-mucin-producing cells were positive for p63 and 34 beta E12, suggesting squamous differentiation. Although most mucin-producing cells were p63-, a few of them were p63+ and many 34 beta E12 immunoreactive cells were found in the mucin-producing cells. This tumor was adenosquamous carcinoma in situ.

Web of Science ® 被引用回数 : 3

リンク情報
DOI
https://doi.org/10.1111/j.1447-0756.2012.01904.x
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000313250800070&DestApp=WOS_CPL

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