J-GLOBAL         Last updated: Apr 1, 2015 at 19:48
Suzuka National College of Technology
Department of Chemistry and Biochemistry
Job title
Docter of Medical Sciences(Tokai University), Master of engineering(Tokai University)

Research Interests


Research Areas



Graduate School, Division of Medicine, Tokai University

Published Papers

Yamaguchi K, Honda M, Ikigai H, Hara Y, Shimamura T
Antiviral research   53 19-34   Jan 2002   [Refereed]
Ikigai H, Otsuru H, Yamamoto K, Shimamura T
Microbiology and immunology   50 751-757   2006   [Refereed]
Kanematsu H, Ikigai H, Yoshitake M
International journal of molecular sciences   10 559-571   Feb 2009   [Refereed]


IKIGAI Hajime, OTSURU Hiroshi, YAMAMOTO Koichiro, SHIMAMURA Tadakatsu
Microbiology and Immunology   50(10) 751-757   Oct 2006
Tagami Yasunobu, Matsufuji Takashi, Ikigai Hajime, Narita Takayuki, Oishi Yushi
Bulletin of the Chemical Society of Japan   82(4) 536-538   2009
We investigated the aggregation state of a mixed monolayer of 1,2-dimyristoyl-sn-glycero-3-phospholine and cholesterol at different surface pressures by AFM. AFM images revealed a nanoscopically separated structure despite a macroscopic homogeniza...
TSUJIYAMA Hiroyuki, IKIGAI Hajime, SHIMAMURA Tadakatsu
The Showa University Journal of Medical Sciences   10(2) 205-212   1998
We studied the synergistic cytotoxicity of E1 Tor hemolysin (ETH, molecular mass ; 65 kDa) produced byVibrio choleraeO1 and live vibrios, such as classical 569B, E1 Tor N86, or Bengal O139 strain, to Intestine 407 cells of a human cell line...
MICROBIOLOGY and IMMUNOLOGY   32(5) 535-540   1988
When mouse polymorphonuclear leukocytes (PMNs) sensitized with rabbit antibody to mouse Ehrlich ascites tumor cells were stimulated by Staphylococcus aureus Cowan I cells, a conspicuous luminol-dependent chemiluminescence was observed in the absen...
TAKI Yoshiharu, SEKI Keiko, IKIGAI Hajime, NISHIHARA Shoko, UENO Hiroshi, MUROTA Kagehisa, MASUDA Shogo
MICROBIOLOGY and IMMUNOLOGY   32(4) 429-434   1988
The effect of temperature on the antibacterial activity of lidocaine to Staphylococcus aureus and Pseudomonas aeruginosa was investigated in vitro. At 10C at which S. aureus organisms do not grow and might be metabolically inactive, the antibacter...

Books etc

Infection prevention in acute leukemia with protected isolation(共著)
Recent advances in germ free research, Tokai University press   1981   
Growth inhibition of Thiobacillus ferrooxidans by some metals. In: Biotechnology of lignocellulose degradation and biomass utilization
Biotechnology of lignocellulose degradation and biomass utilization (Ohmiya, K., Sakka, K., Karita, S., Kimura, T., Sakka, M., and Ohnishi, Y., eds.), Uni Publishers Co., Ltd.   2003   

Research Grants & Projects

Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 1999 - 2001    Investigator(s): Hajime IKIGAI
Vibrio cholerae 01 produces El Tor hemolysin (ETH ; 65 kDa), which expresses obvious strong cytotoxic effects. The ETH forms pore-forming transmembrane oligomers in lipid bilayer membranes that are permeable to smaller molecules less than 600 Da. ...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2004 - 2006    Investigator(s): Hideyuki KANEMATSU
The enhancement of environmental friendliness is one of the most important factors for the development of materials in the 21st century. In Japan where the population of aged people is increasing rapidly, the anti-bacterial materials are desirable...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2009 - 2011    Investigator(s): Hideyuki KANEMATSU
Biofilm formation behaviors were clarified for various metals in marine environments, when they were immersed into Ise Bay. And by using some gene analyses, the species of bacteria in biofilm formed on various specimens in the sea were clarified. ...
Study of bacterial hemolysins
Study of antibacterial substrates in plants
Project Year: 2001