2000年10月
Cleavage of S-S bond by nitric oxide (NO) in the presence of oxygen: A disproportionation reaction of two disulfides
CHEMICAL & PHARMACEUTICAL BULLETIN
- ,
- ,
- 巻
- 48
- 号
- 10
- 開始ページ
- 1524
- 終了ページ
- 1528
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1248/cpb.48.1524
- 出版者・発行元
- PHARMACEUTICAL SOC JAPAN
Disulfide bond was cleaved by a catalytic amount of nitric oxide in the presence of oxygen, which was confirmed by experiments employing two symmetrical disulfides. Thp reaction resulted in the formation of unsymmetrical disulfides in nearly 50% yields. The steric hindrance of alkyl disulfide slowed the reaction rate, and an electron-donating group on the aryl disulfide promoted the reaction. The substituent and S-nitrosothiol effects suggested that the reaction was initialized with an oxidative process by NO+.
- リンク情報
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- DOI
- https://doi.org/10.1248/cpb.48.1524
- CiNii Articles
- http://ci.nii.ac.jp/naid/110003635320
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/11045462
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000089696300025&DestApp=WOS_CPL
- ID情報
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- DOI : 10.1248/cpb.48.1524
- ISSN : 0009-2363
- CiNii Articles ID : 110003635320
- PubMed ID : 11045462
- Web of Science ID : WOS:000089696300025