田中博道 (Hiromichi Tanaka) - マイポータル - researchmap

基本情報

所属: 昭和大学薬学部薬品製造化学教授

学位: 薬学修士(北海道大学)
薬学博士(北海道大学)

J-GLOBAL ID: 200901066190919047
researchmap会員ID: 1000074258

外部リンク: http://www10.showa-u.ac.jp/~omchem/index.html

研究キーワード

4

研究分野

1

ライフサイエンス / 薬系化学、創薬科学 /

委員歴

2

1997年

抗ウイルス化学療法研究会, 世話人
1991年 - 1993年

日本薬学会, 学会誌(ファルマシア)編集委員

受賞

4

MISC

121

Synthesis of a highly active new anti-HIV agent 2 ',3 '-didehydro-3 '-deoxy-4 '-ethynylthymidine

K Haraguchi, S Takeda, H Tanaka, T Nitanda, M Baba, GE Dutschman, YC Cheng

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 13(21) 3775-3777 2003年11月
Synthesis of a highly active new anti-HIV agent 2 ',3 '-didehydro-3 '-deoxy-4 '-ethynylthymidine

K Haraguchi, S Takeda, H Tanaka, T Nitanda, M Baba, GE Dutschman, YC Cheng

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 13(21) 3775-3777 2003年11月
Development of radioiodinated nucleoside analogs for imaging tissue proliferation: comparisons of six 5-iodonucleosides

J Toyohara, A Hayashi, M Sato, A Gogami, H Tanaka, K Haraguchi, Y Yoshimura, H Kumamoto, Y Yonekura, Y Fujibayashi

NUCLEAR MEDICINE AND BIOLOGY 30(7) 687-696 2003年10月
Development of radioiodinated nucleoside analogs for imaging tissue proliferation: comparisons of six 5-iodonucleosides

J Toyohara, A Hayashi, M Sato, A Gogami, H Tanaka, K Haraguchi, Y Yoshimura, H Kumamoto, Y Yonekura, Y Fujibayashi

NUCLEAR MEDICINE AND BIOLOGY 30(7) 687-696 2003年10月
Ring opening of 4 ',5 '-epoxynucleosides: A novel stereoselective entry to 4 '-C-branched nucleosides

K Haraguchi, S Takeda, H Tanaka

ORGANIC LETTERS 5(9) 1399-1402 2003年5月
Ring opening of 4 ',5 '-epoxynucleosides: A novel stereoselective entry to 4 '-C-branched nucleosides

K Haraguchi, S Takeda, H Tanaka

ORGANIC LETTERS 5(9) 1399-1402 2003年5月
Stereoselective Syntesis of 2'-β-Carbon-substituted 2'-Deoxy-4'-thioribonucleosides from 4-Thiofuranoid Glycal

Nucleic Acids Res. Supplement 3, 7-8 2003年
Study on the Reaction Mechanism of C-6 Lithiation of Pyrimidine Nucleosides by Using Lithium Hexamethyldisilazide as a Base

Nucleic Acids Res. Supplement 3, 17-18 2003年
Stereo-defined Syntesis of 5'-(Z)-Substituted 4', 5'-Unsaturated Adenosines and Evalution of their Inhibitory Activity Against S-Adenosyl Homocysteine Hydrolase

Nucleic Acids Res. Supplement 3, 13-14 2003年
4-thiofuranoid glycals: Versatile synthons for stereoselective synthesis of 4 '-thionucleosides

K Haraguchi, H Takahashi, H Tanaka

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS 22(5-8) 763-765 2003年
Stannylation Approach to the Syntesis of 2'- and 3'-Substituted Analogues of 2', 3'-Didehydro-2', 3'-dideoxynucleosides

Nucleosides, Nucleotides, and Nucleic Acids 22, 767-769 2003年
Stereoselective Syntesis of 1'-C-Branched Nucleosides Based on Anomeric Radicals Generated by 1, 2-Acyloxy Migration

J. Org. Chem. 68, 2006-2009 2003年
Syntesis of Oligonucleotides with 6-Formyl-2'-O-methyluridine and Thermal Stability of Their Duplexes

Heterocycles 59, 207-215 2003年
ヌクレオシドの糖部分における炭素－炭素結合の構築：不飽和糖ヌクレオシドの有用性

原口一宏, 伊藤佳治, 田中博道

有機合成化学協会誌 61, 10, 974-983(10) 974-983 2003年
Stereoselective Syntesis of 2'-β-Carbon-substituted 2'-Deoxy-4'-thioribonucleosides from 4-Thiofuranoid Glycal

Nucleic Acids Res. Supplement 3, 7-8 2003年
Study on the Reaction Mechanism of C-6 Lithiation of Pyrimidine Nucleosides by Using Lithium Hexamethyldisilazide as a Base

Nucleic Acids Res. Supplement 3, 17-18 2003年
Stereo-defined Syntesis of 5'-(Z)-Substituted 4', 5'-Unsaturated Adenosines and Evalution of their Inhibitory Activity Against S-Adenosyl Homocysteine Hydrolase

Nucleic Acids Res. Supplement 3, 13-14 2003年
4-thiofuranoid glycals: Versatile synthons for stereoselective synthesis of 4 '-thionucleosides

K Haraguchi, H Takahashi, H Tanaka

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS 22(5-8) 763-765 2003年
Stannylation Approach to the Syntesis of 2'- and 3'-Substituted Analogues of 2', 3'-Didehydro-2', 3'-dideoxynucleosides

Nucleosides, Nucleotides, and Nucleic Acids 22, 767-769 2003年
Stereoselective Syntesis of 1'-C-Branched Nucleosides Based on Anomeric Radicals Generated by 1, 2-Acyloxy Migration

J. Org. Chem. 68, 2006-2009 2003年

もっとみる

書籍等出版物

4

Lithiation-Based Silylation and Stannylation for Nucleoside Synthesis

Recent Advances in Nucleosides: Chemistry and Chemotherapy 2002年
Lithiation-Based Silylation and Stannylation for Nucleoside Synthesis

Recent Advances in Nucleosides: Chemistry and Chemotherapy 2002年
HEPT : From an Investigation of Lithiation of Nucleosides Towards a Rational Design of Non-Nucleoside Reverse Transcriptase Inhibitors of HIV-1

Advances in Antiviral Drug Design 1999年
Lithiation Chemistry of Uridine Derivatives : Access to a New Anti-HIV-1 Lead

Nucleosides and Nucleotides as Antitumor and Antiviral Agents 1993年

所属学協会

4

共同研究・競争的資金等の研究課題

4