Takemi Yoshida - My portal - researchmap

Profile Information

Affiliation: 教授, School of Pharmacy, Showa University
: 代表理事, 公益社団法人薬剤師認定制度認証機構

Degree: (BLANK)

J-GLOBAL ID: 200901091260019787
researchmap Member ID: 1000074287

Research Interests

8

Research Areas

2

Research History

10

Jun, 2011

えｘｅｃｕｔｉｖｅＤｉｒｅｃｔｏｒ, ＣｏｕｎｃｉｌｏｎＰｈａｒｍｃｉｓｔｓＣｒｅｄｅｎｔｉａｌｓ
Apr, 2011

Professor Emeritus, Showa University
1979 - 1992

School of Pharmacy, Showa University
1979 - 1992

Associate Professor Showa Univ., Sch. Pharm. Sci.
1992

- 昭和大学薬学部教授
1992

- Professor, Showa Univ., Sch. Pharm. Sci.
1973 - 1979

Faculty of Pharmaceutical Sciences, Tohoku University
1973 - 1979

assistant professor, Tohoku University, Sch. Pharm. Sci.
1976 - 1977

バンダービルト大学医学部トキシコロジーセンター研究員
1976 - 1977

Research Associate Toxicology Center Vanderbilt University School of Medicine

Education

4

- 1973

Tohoku University
- 1973

Graduate School, Division of Pharmaceutical Sciences, Tohoku University
- 1968

Faculty of Pharmaceutical Sciences, The University of Tokushima
- 1968

Faculty of Pharmaceutical Science, The University of Tokushima

Committee Memberships

5

Jan, 2010 - Dec, 2011

理事長, 日本トキシコロジ-学会(現日本毒性学会）
Nov, 2006 - Oct, 2011

理事長, 日本法科学技術学会(前日本鑑識科学技術学会）
2001

理事, 日本中毒学会
1996

理事, 日本香粧品科学会
1994

理事, 日本法中毒学会

Awards

4

Sep, 2011

学会賞, 日本免疫毒性学会

吉田武美
Mar, 2011

教育賞, 公益社団法人日本薬学会

吉田武美
Jun, 2007

学会賞, 日本トキシコジー学会

吉田武美
Mar, 2007

望月喜多司記念賞・業績賞, 財団法人食品農医薬品安全性評価センター

吉田武美

Papers

8

Chemical-induced coordinated and reciprocal changes in heme metabolism, cytochrome P450 synthesis and others in the liver of humans and rodents

YOSHIDA Takemi, Takashi Ashino, Yasuna Kobayashi

J. Toxicol. Sci., SP89-SP103, 2016 Peer-reviewedInvited
Possible involvement of nuclear factor erythroid 2-related factor 2 in the gene expression of Cyp2b10 and Cyp2a5

Takashi Ashino, Haruyo Ohkubo-Morita, Masayuki Yamamoto, Takemi Yoshida, Satoshi Numazawa

REDOX BIOLOGY, 2 284-288, 2014 Peer-reviewed
Activation of microglia induces symptoms of Parkinson's disease in wild-type, but not in IL-1 knockout mice.

Sachiko Tanaka, Atsuko Ishii, Hirokazu Ohtaki, Seiji Shioda, Takemi Yoshida, Satoshi Numazawa

Journal of neuroinflammation, 10 143-143, Dec 1, 2013 Peer-reviewed
Cross-talk between constitutive androstane receptor and hypoxia-inducible factor in the regulation of gene expression

Ryota Shizu, Sawako Shindo, Takemi Yoshida, Satoshi Numazawa

TOXICOLOGY LETTERS, 219(2) 143-150, May, 2013 Peer-reviewed
Redox-sensitive transcription factor Nrf2 regulates vascular smooth muscle cell migration and neointimal hyperplasia

Takashi Ashino, Masayuki Yamamoto, Takemi Yoshida, Satoshi Numazawa

Arteriosclerosis, Thrombosis, and Vascular Biology, 33(4) 760-768, Apr, 2013 Peer-reviewed
Identification of Hic-5 as a novel regulatory factor for integrin aIIb ss 3 activation and platelet aggregation in mice

J. -R. Kim-Kaneyama, A. Miyauchi, X. -F. Lei, S. Arita, T. Mino, N. Takeda, K. Kou, K. Eto, T. Yoshida, T. Miyazaki …

JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 10(9) 1867-1874, Sep, 2012 Peer-reviewed
MicroRNA-122 Down-Regulation Is Involved in Phenobarbital-Mediated Activation of the Constitutive Androstane Receptor

Ryota Shizu, Sawako Shindo, Takemi Yoshida, Satoshi Numazawa

PLOS ONE, 7(7) e41291, Jul, 2012 Peer-reviewed
Involvement of Interleukin-1 in Lead Nitrate-Induced Hypercholesterolemia in Mice

Misaki Kojima, Takashi Ashino, Takemi Yoshida, Yoichiro Iwakura, Masakuni Degawa

BIOLOGICAL & PHARMACEUTICAL BULLETIN, 35(2) 246-250, Feb, 2012 Peer-reviewed

Misc.

89

有害事象発生時の対応と食物テロへの対応

吉田武美

薬学雑誌, 128(6) 851-857, 2008 Peer-reviewedInvited
スポーツとどーピング

吉田武美

中毒研究, 16 288-305, 2003 Peer-reviewedInvited
Absorption, Distriburtion and excretion of 3H-labeled cephacethine- and emetine-spiked ipecac syrup in rats

Eur.J.Drug Metab. Pharmascokin., 27, 17-27, 2002
Involvement of Tumor Necrosis Factor α, rather than Interleukin-α/β or Nitric Oxides in the Heme Oxygenase-1 Gene Expression by Lipoplysaccharide in the Mouse Liver

FEBS Lett., 516, 63-66, 2002
Induction and Inhibition of Cytochrome P450 and Drug-metabolizing Enzymes by Climbazole

Biol.Pharm.Bull., 25, 51-57, 2002
Absorption, Distriburtion and excretion of 3H-labeled cephacethine- and emetine-spiked ipecac syrup in rats

Eur.J.Drug Metab. Pharmascokin., 27, 17-27, 2002
Involvement of Tumor Necrosis Factor α, rather than Interleukin-α/β or Nitric Oxides in the Heme Oxygenase-1 Gene Expression by Lipoplysaccharide in the Mouse Liver

FEBS Lett., 516, 63-66, 2002
Induction and Inhibition of Cytochrome P450 and Drug-metabolizing Enzymes by Climbazole

Biol.Pharm.Bull., 25, 51-57, 2002
Effect of ultraviolet A on ornithine decarboxylase and metallothionein gene expression in mouse skin

T Oguro, T Yoshida

PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE, 17(2) 71-78, Apr, 2001
Role of CYP2C19 in stereoselective hydroxylation of mephobarbital by human liver microsomes

K Kobayashi, M Kogo, M Tani, N Shimada, T Ishizaki, S Numazawa, T Yoshida, T Yamamoto, Y Kuroiwa, K Chiba

DRUG METABOLISM AND DISPOSITION, 29(1) 36-40, Jan, 2001
Determination of bufalin-like immunoreactivity in serum of humans and rats by time-resolved fluoroimmunoassay for using a monoclonal antibody

M Oda, M Kurosawa, S Numazawa, S Tanaka, T Akizawa, K Ito, M Maeda, T Yoshida

LIFE SCIENCES, 68(10) 1107-1117, Jan, 2001
Participation of CYP2A in Cocaine-induced Hepatotoxicity in Female Rats

Pharmacol. Toxicol., 87(1) 26-32, 2000
Concurrent Induction of Rat Hepatic Microsoma Cytochrome P450 and Haem Oxygenase by 2, 2-Dipyridil Ketone : Comparison With The Effect of 2, 2-Dipiridyl Amine

Xenobiotica, 30(7) 683-692, 2000
ERK Signaling Mediates the Induciton of Inflammatory Cytokines by Bufalin in Human Monocytic Cells

Am. J. Physiol. Cell Physiol., 278 C500-C508, 2000
Induction of hepatic CYP2B1/2 by a teratogenic compound cis-1-[-4-(P- menthane-8-yloxy)phenyl]piperadine (YM9429) in rats

Satoshi Numazawa, Masakatsu Shibata, Susumu Imaoka, Yoshihiko Funae, Takemi Yoshida

Journal of Toxicological Sciences, 25(1) 57-61, 2000
酸化ストレスとＨｅｍｅＯｘｙｇｅｎａｓｅ－１

吉田武美

日本医学館, 15 31-36, 2000
Interlaboratory validation of the in vitro eye irritation tests for cosmetic ingredients. (1) Overview of the validation study and Draize scores for the evaluation of the tests

Y Ohno, T Kaneko, T Inoue, Y Morikawa, T Yoshida, A Fujii, M Masuda, T Ohno, M Hayashi, J Momma …

TOXICOLOGY IN VITRO, 13(1) 73-98, Feb, 1999
薬毒物中毒について

モダンメディア, 45 185-193, 1999
ヒト有棘細胞癌株細胞(SSCC-1)の増殖分化に対するブファリンの作用

12 205-208, 1999
Organ distribution and toxicity of lignin

H Sakagami, K Asano, T Yoshida, Y Kawazoe

IN VIVO, 13(1) 41-44, Jan, 1999

More

Books and Other Publications

20

薬毒物試験法と注解2017

吉田武美 (Role: Joint editor)

東京化学同人, May, 2017
Drug Toxicology

YOSHIDA Takemi (Role: Contributor, organ toxicity)

Nankodo, 2010
Clinical Pharmacology

YOSHIDA Takemi (Role: Contributor, noclinical testing)

2010
Anticholinesterase Pesticides: Metabolism,Neurotoxicity and Epidemiology

YOSHIDA Takemi (Role: Joint author)

John Wiley & Sons, 2010
Ｎｅｗ医薬品の安全性学

吉田武美 (Role: Editor)

廣川書店, 2010
薬物代謝学~医療薬学・医薬品開発の基礎として~第3版

吉田武美 (Role: Contributor, 薬物代謝と毒性発現)

東京化学同人, Jan, 2010
予防薬学としての衛生薬学ー健康と環境ー

吉田武美 (Role: Contributor)

廣川書店, 2009
非臨床試験-儀ドラインへの対応と新しい試みー

吉田武美 (Role: Joint editor)

エルアイシー, 2008
キャサレット＆ﾄﾞールトキシコロジー

吉田武美 (Role: Supervisor (editorial))

2004
臨床のための法医学第4版

朝倉書店, 2001
知っておきたい毒の知識

薬事日報社, 2001
生物薬科学実験講座 15薬物代謝酵素

廣川書店, 2001
Analytical Toxicology for Clinical, Forensic and Pharmaceutical Chemists(共著)

Walter de Gruyter, Berlin, 1997
医薬品トキシコロジー (共著)

南江堂, 1996
裁判化学 (共著)

南江堂, 1996
薬学生のための毒性学 (共著)

廣川書店, 1996
薬物代謝学 -医療薬学・毒性学の基礎として (共著)

東京化学同人, 1995
薬の安全性 -その基礎知識 (共著)

南山堂, 1995
毒性学(改訂第三版)

1991
トキシコロジー

1988

Professional Memberships

12

Research Projects

6