Ryuhei Kanamoto

Profile Information

Affiliation: Kyoto University

Degree: Doctor of Agriculture(Kyoto University)

J-GLOBAL ID: 200901018982419691
researchmap Member ID: 1000078458

External link: http://www.kpu.ac.jp

Research Interests

Research Areas

Life sciences / Food sciences /

Research History

Kyoto Prefectural University

Education

- 1981

Kyoto University
- 1981

Graduate School, Division of Agriculture, Kyoto University
- 1976

Faculty of Agriculture, Kyoto Prefectural University
- 1976

Faculty of Agriculture, Kyoto Prefectural University

Papers

delta-Opioid receptor activation stimulates normal diet intake but conversely suppresses high-fat diet intake in mice

Kentaro Kaneko, Takafumi Mizushige, Yuri Miyazaki, Michael Lazarus, Yoshihiro Urade, Masaaki Yoshikawa, Ryuhei Kanamoto, Kousaku Ohinata

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 306(4) R265-R272, Feb, 2014 Peer-reviewed
Identification of novel beta-lactoglobulin-derived peptides, wheylin-1 and -2, having anxiolytic-like activity in mice

Ayako Yamada, Takafumi Mizushige, Ryuhei Kanamoto, Kousaku Ohinata

MOLECULAR NUTRITION & FOOD RESEARCH, 58(2) 353-358, Feb, 2014 Peer-reviewed
Characterization of Ile-His-Arg-Phe, a novel rice-derived vasorelaxing peptide with hypotensive and anorexigenic activities

Noriyasu Kontani, Ryo Omae, Tomomi Kagebayashi, Kentaro Kaneko, Yuko Yamada, Takafumi Mizushige, Ryuhei Kanamoto, Kousaku Ohinata

MOLECULAR NUTRITION & FOOD RESEARCH, 58(2) 359-364, Feb, 2014 Peer-reviewed
Characterization of Tyr-Leu-Gly, a novel anxiolytic-like peptide released from bovine alpha(S)-casein

Takafumi Mizushige, Yurina Sawashi, Ayako Yamada, Ryuhei Kanamoto, Kousaku Ohinata

FASEB JOURNAL, 27(7) 2911-2917, Jul, 2013 Peer-reviewed
The Vagotomy Alleviates the Anorectic Effect of an Excess Amount of Dietary Leucine on Rats Fed a Low-Protein Diet

Ryoji Yoshimura, Yee Yin Ho, Takafumi Mizushige, Kousaku Ohinata, Ryuhei Kanamoto

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 77(7) 1593-1594, Jul, 2013 Peer-reviewed
Aromatic amino acid-leucine dipeptides exhibit anxiolytic-like activity in young mice

Takafumi Mizushige, Norimasa Kanegawa, Ayako Yamada, Ami Ota, Ryuhei Kanamoto, Kousaku Ohinata

Neuroscience Letters, 543 126-129, May 24, 2013 Peer-reviewed
Adverse Effects of Excessive Leucine Intake Depend on Dietary Protein Intake: A Transcriptomic Analysis to Identify Useful Biomarkers

Wataru Imamura, Ryoji Yoshimura, Marie Takai, Junki Yamamura, Ryuhei Kanamoto, Hisanori Kato

JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY, 59(1) 45-55, Feb, 2013 Peer-reviewed
Importance of uncharged polar residues and proline in the proximal two-thirds (Pro107-Ser128) of the highly conserved region of mouse ileal Na+-dependent bile acid transporter, Slc10a2, in transport activity and cellular expression

Tohru Saeki, Kosuke Sato, Shiho Ito, Keisuke Ikeda, Ryuhei Kanamoto

BMC Physiology, 13(1), 2013 Peer-reviewed
Ursodeoxycholic Acid Protects Colon Cancer HCT116 Cells From Deoxycholic Acid-Induced Apoptosis by Inhibiting Apoptosome Formation

Tohru Saeki, Satoko Yui, Tadashi Hirai, Takami Fujii, Sawami Okada, Ryuhei Kanamoto

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 64(4) 617-626, 2012 Peer-reviewed
Mutational Analysis of Uncharged Polar Residues and Proline in the Distal One-Third (Thr(130)-Pro(142)) of the Highly Conserved Region of Mouse Slc10a2

Tohru Saeki, Satoko Mizushima, Kazumitsu Ueda, Kimikazu Iwami, Ryuhei Kanamoto

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 73(7) 1535-1540, Jul, 2009 Peer-reviewed
Biphasic Regulation of Cell Death and Survival by Hydrophobic Bile Acids in HCT116 Cells

Satoko Yui, Ryuhei Kanamoto, Tohru Saeki

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 61(3) 374-380, May, 2009 Peer-reviewed
Soybean Resistant Protein Elevates Fecal Excretion of Cholesterol and Bile Acids and Decreases Hepatic Cholesterol Content in Comparison with Soybean Protein Isolate

Keiko Yamatani, Tohru Saeki, Kimikazu Iwami, Tomohiko Suzuka, Ryuhei Kanamoto

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 73(4) 921-922, Apr, 2009 Peer-reviewed
Deoxycholic acid can induce apoptosis in the human colon cancer cell line HCT116 in the absence of bax

Satoko Yui, Ryuhei Kanamoto, Tohru Saeki

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 60(1) 91-96, Jan, 2008 Peer-reviewed
Excess leucine intake induces serine dehydratase in rat liver

Bo Zhong, Shunsuke Sakai, Tohru Saeki, Ryuhei Kanamoto

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 71(10) 2614-2617, Oct, 2007 Peer-reviewed
Effects of ala substitution for conserved Cys residues in mouse ileal and hepatic Na+-dependent bile acid transporters

Tohru Saeki, Yuki Munetaka, Kazurnitsu Ueda, Kimikazu Iwami, Ryuhei Kanamoto

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 71(8) 1865-1872, Aug, 2007 Peer-reviewed
Taurocholic acid does not induce apoptosis in HCT116 cells regardless of its intracellular concentration

Satoko Yui, Ryuhei Kanamoto, Kimikazu Iwami, Tohru Saeki

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 71(3) 800-802, Mar, 2007 Peer-reviewed
Evidence for the existence of a soybean resistant protein that captures bile acid and stimulates its fecal excretion

Noriko Higaki, Kenji Sato, Hitoshi Suda, Tomohiko Suzuka, Takeo Komori, Tohru Saeki, Yasushi Nakamura, Kozo Ohtsuki, Kimikazu Iwami, Ryuhei Kanamoto

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 70(12) 2844-2852, Dec, 2006 Peer-reviewed
Characteristics of apoptosis in HCT116 colon cancer cells induced by deoxycholic acid

S Yui, T Saeki, R Kanamoto, K Iwami

JOURNAL OF BIOCHEMISTRY, 138(2) 151-157, Aug, 2005 Peer-reviewed
Inverse correlation between the nitrogen balance and induction of rat liver serine dehydratase (SDH) by dietary protein

R Kanamoto, K Fujita, M Kumasaki, S Imai, M Kotaru, T Saeki, K Iwami

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 68(4) 888-893, Apr, 2004 Peer-reviewed
Characterization of cloned mouse Na+/taurocholate cotransporting polypeptide by transient expression in COS-7 cells

T Saeki, N Takahashi, R Kanamoto, K Iwami

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 66(5) 1116-1118, May, 2002 Peer-reviewed

Misc.

Yui, S., Saeki, T., Kanamoto, R., and Iwami, K., Characteristics of apoptosis in HCT116 colon cancer cells induced by deoxycholic acid.

J Biochem (Tokyo), 138, 151-157, 2005
アミノ酸過剰摂取によるラット肝セリン脱水酵素の誘導と血中アミノ酸の動態

必須アミノ酸研究, 169, 7-11, 2004
Inverse correlation between the nitrogen balance and induction of rat liver serine dehydratase (SDH) by dietary protein

Biosci Biotechnol Biochem, 68 (4) 888-893, 2004
Response of the induction of rat liver serine dehydratase to changes in the dietary protein requirement

S Imai, R Kanamoto, Yagi, I, M Kotaru, T Saeki, K Iwami

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 67(2) 383-387, Feb, 2003
アミノ酸ホメオスタシス維持におけるセリン脱水酵素の役割

必須アミノ酸研究, 167, 42-48, 2003
Characterization of cloned mouse Na+/taurocholate cotransporting polypeptide by transient expression in COS-7 cells

T Saeki, N Takahashi, R Kanamoto, K Iwami

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 66(5) 1116-1118, May, 2002
糞中ステロイド排泄増加における大豆レジスタントプロテインの中心的役割と捕捉胆汁酸の構造特異性

大豆たん白質研究, 5, 58-62, 2002
Effects of Cys mutation on taurocholic acid transport by mouse ileal and heptic sodium-dependent bile acid transporters

Biosci Biotechnol Biochem, 66 (2) 467-470, 2002
Non-involvement of the K-ras mutation in colon carcinogenesis promoted by dietary deoxycholate in azoxymethane-treated rats

R Kanamoto, N Azuma, Y Tsuchihashi, H Suda, T Saeki, K Iwami

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 65(4) 848-852, Apr, 2001
大豆レジスタントプロティンによる胆汁酸の腸管循環の阻害と、アゾキシメタンと食餌性デオキシコール酸によって誘発したラット肝発がんの抑制

Bioscience, Biotechnology, and Biochemistry, 65(4) 999-1002, 2001
アゾキシメタンと食餌性デオキシコール酸で誘発したラットの大腸がんはK-rasの変異を伴わない

Bioscience, Biotechnology, and Biochemistry, 65(4) 848-852, 2001
Soybean resistant proteins interrupt an enterohepatic circulation of bile acids and sappress hepatocarcinogenesis induced by azoxymetare and dietary deoxycholate in rat

Biosci. Biotechnol. Biochem., 65(4) 999-1002, 2001
薬物誘発大腸および肝腫瘍モデルにおける胆汁酸トランスポーターの影響

アークメディア・肝胆膵, 41(5), 2000
Effect of the ileal Na⁺-dependent bile and transportor on colon and liver carcinogenesis induced by chemical carcinogen

41(5), 2000
Antitumorigenic effects of several food proteins in a rat model of colon cancer and their reverse correlation with plasma bile acid concentration

J. Nutr. Sci. Vitaminol, 46(2) 91-96, 2000
Preventive effect of soybean resistant protein against experimental tumorigenesis in rat colon

J. Nutr. Sci. Vitaminol, 46(1) 23-29, 2000
Soybean curd refuse alleviates experimental tumorigenesis in rat colon

N Azuma, H Suda, H Iwasaki, R Kanamoto, K Iwami

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 63(12) 2256-2258, Dec, 1999
Elimination of Na+-dependent bile acid transporter from small intestine by ileum resection increase colonic tumorigenesis in the rat fed deoxycholic acid

R Kanamoto, N Azuma, H Suda, T Seki, Y Tsuchihashi, K Iwami

CANCER LETTERS, 145(1-2) 115-120, Oct, 1999
Characterization, cDNA cloning, and functional expression of mouse ileal sodium-dependent bile acid transporter

T Saeki, K Matoba, H Furukawa, K Kirifuji, R Kanamoto, K Iwami

JOURNAL OF BIOCHEMISTRY, 125(4) 846-851, Apr, 1999
タンパク質必要量とセリン脱水酵素の誘導について

必須アミノ酸研究, 157, 45-48, 1999

Books and Other Publications

エキスパート管理栄養士養成シリーズ14 分子栄養学

金本龍平

化学同人, 2005
ヒューマンニュートリション

細谷憲政, 日本語版監修代表

医歯薬出版, 2004
栄養機能化学

栄養機能化学研究会

朝倉書店, 1996

Profile Information

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Research History

Education

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