2007年10月
Excess leucine intake induces serine dehydratase in rat liver
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
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- 巻
- 71
- 号
- 10
- 開始ページ
- 2614
- 終了ページ
- 2617
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1271/bbb.70512
- 出版者・発行元
- TAYLOR & FRANCIS LTD
We have hypothesized that rat liver serine dehydratase (SDH) is induced in response to the amount of surplus amino acids from dietary protein. In the present study, we found that excess leucine intake strongly induced SDH activity in the liver but not in the kidney of rats. The increase in activity was accompanied by increases in the levels of SDH mRNA. On the other hand, isoleucine and valine had little effect on SDH induction. These results support our hypothesis and suggest that leucine is a signal for SDH induction.
- リンク情報
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- DOI
- https://doi.org/10.1271/bbb.70512
- CiNii Articles
- http://ci.nii.ac.jp/naid/10027520465
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/17928680
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000250669000043&DestApp=WOS_CPL
- ID情報
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- DOI : 10.1271/bbb.70512
- ISSN : 0916-8451
- eISSN : 1347-6947
- CiNii Articles ID : 10027520465
- PubMed ID : 17928680
- Web of Science ID : WOS:000250669000043