論文

査読有り
2007年10月

Excess leucine intake induces serine dehydratase in rat liver

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
  • Bo Zhong
  • ,
  • Shunsuke Sakai
  • ,
  • Tohru Saeki
  • ,
  • Ryuhei Kanamoto

71
10
開始ページ
2614
終了ページ
2617
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1271/bbb.70512
出版者・発行元
TAYLOR & FRANCIS LTD

We have hypothesized that rat liver serine dehydratase (SDH) is induced in response to the amount of surplus amino acids from dietary protein. In the present study, we found that excess leucine intake strongly induced SDH activity in the liver but not in the kidney of rats. The increase in activity was accompanied by increases in the levels of SDH mRNA. On the other hand, isoleucine and valine had little effect on SDH induction. These results support our hypothesis and suggest that leucine is a signal for SDH induction.

リンク情報
DOI
https://doi.org/10.1271/bbb.70512
CiNii Articles
http://ci.nii.ac.jp/naid/10027520465
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/17928680
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000250669000043&DestApp=WOS_CPL
ID情報
  • DOI : 10.1271/bbb.70512
  • ISSN : 0916-8451
  • eISSN : 1347-6947
  • CiNii Articles ID : 10027520465
  • PubMed ID : 17928680
  • Web of Science ID : WOS:000250669000043

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