Jin Takeuchi

Profile Information

Affiliation: School of Medicine, Nihon University

Degree: Ph.D.(Nihon University)

J-GLOBAL ID: 200901030314341974
researchmap Member ID: 1000085063

Research Interests

血液内科学

Research Areas

Life sciences / Hematology and oncology /

Research History

Apr, 2006 - Mar, 2013

professor, Department of hematology and rheumatology, Nihon University School of medicine

Committee Memberships

Papers

120

Clinical usefulness of WT1 mRNA expression in bone marrow detected by a new WT1 mRNA assay kit for monitoring acute myeloid leukemia: a comparison with expression of WT1 mRNA in peripheral blood

Kunio Kitamura, Takahiro Nishiyama, Ken Ishiyama, Shuichi Miyawaki, Kanji Miyazaki, Kenshi Suzuki, Hiroaki Masaie, Masaya Okada, Hiroyasu Ogawa, Kiyotoshi Imai …

INTERNATIONAL JOURNAL OF HEMATOLOGY, 103(1) 53-62, Jan, 2016 Peer-reviewed
Identification of a novel E-box binding pyrrole-imidazole polyamide inhibiting MYC-driven cell proliferation

Rajeev Mishra, Takayoshi Watanabe, Makoto T. Kimura, Nobuko Koshikawa, Maki Ikeda, Shota Uekusa, Hiroyuki Kawashima, Xiaofei Wang, Jun Igarashi, Diptiman Choudhury …

CANCER SCIENCE, 106(4) 421-429, Apr, 2015 Peer-reviewed
Safety and efficacy of high-dose cyclophosphamide, etoposide and ranimustine regimen followed by autologous peripheral blood stem cell transplant for patients with diffuse large B-cell lymphoma

Yujin Kobayashi, Yoshihiro Hatta, Masahiko Sugitani, Atsuko Hojo, Masaru Nakagawa, Machiko Kusuda, Yoshihito Uchino, Hiromichi Takahashi, Satomi Kiso, Yukio Hirabayashi …

LEUKEMIA & LYMPHOMA, 55(11) 2514-2519, Nov, 2014 Peer-reviewed
Enhancement of differentiation induction and upregulation of CCAAT/enhancer-binding proteins and PU.1 in NB4 cells treated with combination of ATRA and valproic acid

Noriyoshi Iriyama, Bo Yuan, Yuta Yoshino, Yoshihiro Hatta, Akira Horikoshi, Shin Aizawa, Masami Takei, Jin Takeuchi, Norio Takagi, Hiroo Toyoda

INTERNATIONAL JOURNAL OF ONCOLOGY, 44(3) 865-873, Mar, 2014 Peer-reviewed
Efficacy of Molecular Response at 1 or 3 Months after the Initiation of Dasatinib Treatment Can Predict an Improved Response to Dasatinib in Imatinib-Resistant or Imatinib-Intolerant Japanese Patients with Chronic Myelogenous Leukemia during the Chronic P

TAKEUCHI Jin

J Clin Exp Hematop, 54(3) 197-204, 2014 Peer-reviewed
Marked improvement of Churg-Strauss syndrome neuropathy by intravenous immunoglobulin and cyclophosphamide

Akira Umeda, Tateki Yamane, Jin Takeuchi, Yasuo Imai, Keisuke Suzuki, Wako Yumura

Respirology Case Reports, 2(2) 81-84, 2014 Peer-reviewed
Induced differentiation of human myeloid leukemia cells into m2 macrophages by combined treatment with retinoic Acid and 1α,25-dihydroxyvitamin d3.

TAKEUCHI Jin

PLoS One, 19(9) e113722, 2014 Peer-reviewed
Relative increase in lymphocytes from as early as 1 month predicts improved response to dasatinib in chronic-phase chronic myelogenous leukemiaRelative increase in lymphocytes from as early as 1 month predicts improved response to dasatinib in chronic-pha

TAKEUCHI Jin

Int J Hematol., 99(1) 41-52, Jan, 2014 Peer-reviewed
Prognosis of patients with core binding factor acute myeloid leukemia after first relapse

Saiko Kurosawa, Shuichi Miyawaki, Takuhiro Yamaguchi, Heiwa Kanamori, Toru Sakura, Yukiyoshi Moriuchi, Fumiaki Sano, Takeshi Kobayashi, Atsushi Yasumoto, Kazuo Hatanaka …

HAEMATOLOGICA, 98(10) 1525-1531, Oct, 2013 Peer-reviewed
The demarcation between younger and older acute myeloid leukemia patients: A pooled analysis of 3 prospective studies

Masamitsu Yanada, Shigeki Ohtake, Shuichi Miyawaki, Hisashi Sakamaki, Toru Sakura, Tomoya Maeda, Koichi Miyamura, Norio Asou, Iekuni Oh, Junichi Miyatake …

Cancer, 119(18) 3326-3333, Sep 15, 2013 Peer-reviewed
Successful childbearing in two women with rheumatoid arthritis and a history of miscarriage after etanercept treatment

Ikumi Natsumi, Yoshihiro Matsukawa, Kohji Miyagawa, Hitomi Kodaira, Toshitake Tanaka, Akira Horikoshi, Jin Takeuchi, Masami Takei, Mamoru Maejima, Jun Akimoto

RHEUMATOLOGY INTERNATIONAL, 33(9) 2433-2435, Sep, 2013 Peer-reviewed
CD56 expression is an independent prognostic factor for relapse in acute myeloid leukemia with t(8;21)

Noriyoshi Iriyama, Yoshihiro Hatta, Jin Takeuchi, Yoshiaki Ogawa, Shigeki Ohtake, Toru Sakura, Kinuko Mitani, Fumihiro Ishida, Masatomo Takahashi, Tomoya Maeda …

LEUKEMIA RESEARCH, 37(9) 1021-1026, Sep, 2013 Peer-reviewed
Clinical evaluation of WT1 mRNA expression levels in peripheral blood and bone marrow in patients with myelodysplastic syndromes

Yasunori Ueda, Chisato Mizutani, Yasuhito Nannya, Mineo Kurokawa, Sumiko Kobayashi, Jin Takeuchi, Hideto Tamura, Kiyoyuki Ogata, Kazuo Dan, Hirohiko Shibayama …

LEUKEMIA & LYMPHOMA, 54(7) 1450-1458, Jul, 2013 Peer-reviewed
Aquaporin 9, a promising predictor for the cytocidal effects of arsenic trioxide in acute promyelocytic leukemia cell lines and primary blasts

Noriyoshi Iriyama, Bo Yuan, Yuta Yoshino, Yoshihiro Hatta, Akira Horikoshi, Shin Aizawa, Jin Takeuchi, Hiroo Toyoda

Oncology Reports, 29(6) 2362-2368, Jun, 2013 Peer-reviewed
Efficacy of a dose-intensified CHOP (Double-CHOP) regimen for peripheral T-cell lymphomas

Noriyoshi Iriyama, Hiromichi Takahashi, Yoshihiro Hatta, Katsuhiro Miura, Yujin Kobayashi, Daisuke Kurita, Yukio Hirabayashi, Atsuko Hojo, Hitomi Kodaira, Mai Yagi …

ONCOLOGY REPORTS, 29(2) 805-811, Feb, 2013 Peer-reviewed
Staphylococcus aureus sepsis after etanercept induction in a hemodialysis patient

Natsumi Ikumi, Yoshihiro Matsukawa, Yoshikazu Kuwana, Hitomi Kodaira, Toshitake Tanaka, Noriaki Maruyama, Sakiko Nozawa, Akira Horikoshi, Jin Takeuchi

HEMODIALYSIS INTERNATIONAL, 17(1) 133-135, Jan, 2013 Peer-reviewed
Diagnostic Value of Open Biopsy for Malignant T-Cell Lymphoma of the Liver

Akihisa Hojo, Hisashi Nakayama, Osamu Aramaki, Tokio Higaki, Masamichi Moriguchi, Masahiko Sugitani, Katsuhiro Miura, Jin Takeuchi, Ryu Nishiyama, Mitsuhiko Moriyama …

INTERNATIONAL SURGERY, 98(1) 13-18, Jan, 2013 Peer-reviewed
The Significance of Genome-based Diagnosis for the Bacillus Cereus Species

Noriyoshi Iriyama, Yoshihito Uchino, Ken Matsumoto, Yoshihiro Hatta, Jin Takeuchi

INTERNAL MEDICINE, 52(5) 651-651, 2013 Peer-reviewed
Efficacy of oral cytarabine ocfosfate and etoposide in the treatment of elderly patients with higher-risk myelodysplastic syndromes compared to that in elderly acute myeloid leukemia patients

Akira Horikoshi, Noriyoshi Iriyama, Yukio Hirabayashi, Hitomi Kodaira, Yoshihiro Matsukawa, Yoshihito Uchino, Hiromichi Takahashi, Yoshihiro Hatta, Jin Takeuchi, Sumiko Kobayashi …

Chemotherapy, 59(2) 152-158, 2013 Peer-reviewed
Efficacy of oral cytarabine ocfosfate and etoposide in the treatment of elderly patients with higher-risk myelodysplastic syndromes compared to that in elderly acute myeloid leukemia patients

Akira Horikoshi, Noriyoshi Iriyama, Yukio Hirabayashi, Hitomi Kodaira, Yoshihiro Matsukawa, Yoshihito Uchino, Hiromichi Takahashi, Yoshihiro Hatta, Jin Takeuchi, Sumiko Kobayashi …

Chemotherapy, 59(2) 152-158, 2013 Peer-reviewed

Misc.

Prognosis of acute myeloid leukemia harboring monosomal karyotype in patients treated with or without allogeneic hematopoietic cell transplantation after achieving complete remission

Masamitsu Yanada, Saiko Kurosawa, Takuhiro Yamaguchi, Takuya Yamashita, Yukiyoshi Moriuchi, Hiroatsu Ago, Jin Takeuchi, Hirohisa Nakamae, Jun Taguchi, Toru Sakura …

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 97(6) 915-918, Jun, 2012
Efficacy and safety of antifungal prophylaxis with oral itraconazole solution among patients receiving corticosteroids: who should be given prophylaxis?

Noriyoshi Iriyama, Yoshihiro Matsukawa, Katsuhiro Miura, Hirotake Inomata, Yukio Hirabayashi, Yoshihiro Hatta, Akira Horikoshi, Jin Takeuchi

JOURNAL OF INFECTION AND CHEMOTHERAPY, 17(6) 744-749, Dec, 2011
Azacitidine induces demethylation of p16INK4a and inhibits growth in adult T-cell leukemia/lymphoma

Kumi Uenogawa, Yoshihiro Hatta, Naomichi Arima, Satoshi Hayakawa, Umihiko Sawada, Shin Aizawa, Tatsuo Yamamoto, Jin Takeuchi

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 28(5) 835-839, Nov, 2011
Novel three-dimensional long-term bone marrow culture system using polymer particles with grafted epoxy-polymer-chains supports the proliferation and differentiation of hematopoietic stem cells

Yukio Hirabayashi, Yoshihiro Hatta, Jin Takeuchi, Isao Tsuboi, Tomonori Harada, Kentaro Ono, Wilhelm Robert Glomm, Masahiro Yasuda, Shin Aizawa

EXPERIMENTAL BIOLOGY AND MEDICINE, 236(11) 1342-1350, Nov, 2011
Successful treatment of Hodgkin lymphoma in second trimester of pregnancy: feasibility of ABVD regimen

Noriyoshi Iriyama, Akira Horikoshi, Toshitake Tanaka, Yukio Hirabayashi, Hitomi Kodaira, Yoshihiro Hatta, Jin Takeuchi

INTERNATIONAL JOURNAL OF HEMATOLOGY, 94(1) 104-107, Jul, 2011
An effective salvage treatment using ifosfamide, etoposide, cytarabine, dexamethasone, and rituximab (R-IVAD) for patients with relapsed or refractory aggressive B-cell lymphoma

Katsuhiro Miura, Kazuhiro Takei, Sumiko Kobayashi, Satomi Kiso, Yukio Hirabayashi, Atsuko Hojo, Hitomi Kodaira, Mai Yagi, Daisuke Kurita, Yujin Kobayashi …

INTERNATIONAL JOURNAL OF HEMATOLOGY, 94(1) 90-96, Jul, 2011
Charlson Comorbidity Index is an independent prognostic factor among elderly patients with diffuse large B-cell lymphoma

Yujin Kobayashi, Katsuhiro Miura, Atsuko Hojo, Yoshihiro Hatta, Toshitake Tanaka, Daisuke Kurita, Noriyoshi Iriyama, Sumiko Kobayashi, Jin Takeuchi

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 137(7) 1079-1084, Jul, 2011
Successful treatment of refractory acute GVHD complicated by severe intestinal transplant-associated thrombotic microangiopathy using recombinant thrombomodulin

Yasuyuki Inoue, Yoshihiro Hatta, Jin Takeuchi, Shigeki Kosugi, Ikuo Miura

THROMBOSIS RESEARCH, 127(6) 603-604, Jun, 2011
Does more intensive therapy have effects on mantle cell lymphoma? A clinical experience from the Lymphoma Treatment Study Group in Japan

Katsuhiro Miura, Hirotaka Takasaki, Hideki Tsujimura, Masatoshi Kanno, Yoshinobu Maeda, Naoto Tomita, Kazue Takai, Yasufumi Masaki, Jun Takizawa, Hiraku Mori …

INTERNATIONAL JOURNAL OF HEMATOLOGY, 93(5) 684-686, May, 2011
Highly activated oral bioavailability of tacrolimus on coadministration of oral voriconazole

Y. Inoue, T. Saito, M. Takimoto, K. Ogawa, Y. Shibuya, Y. Suzuki, M. Kato, M. Takahashi, I. Miura, Y. Hatta …

INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 49(4) 291-292, Apr, 2011
Highly activated oral bioavailability of tacrolimus on coadministration of oral voriconazole

Y. Inoue, T. Saito, M. Takimoto, K. Ogawa, Y. Shibuya, Y. Suzuki, M. Kato, M. Takahashi, I. Miura, Y. Hatta …

INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 49(4) 291-292, Apr, 2011
Comparison of Allogeneic Hematopoietic Cell Transplantation and Chemotherapy in Elderly Patients with Non-M3 Acute Myelogenous Leukemia in First Complete Remission

Saiko Kurosawa, Takuhiro Yamaguchi, Naoyuki Uchida, Shuichi Miyawaki, Kensuke Usuki, Masato Watanabe, Takuya Yamashita, Heiwa Kanamori, Junji Tomiyama, Yuichiro Nawa …

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 17(3) 401-411, Mar, 2011
A decision analysis of allogeneic hematopoietic stem cell transplantation in adult patients with Philadelphia chromosome-negative acute lymphoblastic leukemia in first remission who have an HLA-matched sibling donor

S. Kako, S. Morita, H. Sakamaki, H. Ogawa, T. Fukuda, S. Takahashi, H. Kanamori, M. Onizuka, K. Iwato, R. Suzuki …

LEUKEMIA, 25(2) 259-265, Feb, 2011
A Markov decision analysis of allogeneic hematopoietic cell transplantation versus chemotherapy in patients with acute myeloid leukemia in first remission

Saiko Kurosawa, Takuhiro Yamaguchi, Shuichi Miyawaki, Naoyuki Uchida, Heiwa Kanamori, Kensuke Usuki, Takuya Yamashita, Masato Watanabe, Kazuaki Yakushiji, Shingo Yano …

BLOOD, 117(7) 2113-2120, Feb, 2011
Positive expression of macrophage inflammatory protein-1α and -1β in a patient with diffuse large B-cell lymphoma accompanied by hypercalcemia and multiple osteolysis.

TAKEUCHI Jin, Kobayashi Y, Hatta Y, Hirabayashi Y, Hojo A, Tanaka T, Takei K, Ishizuka H, Sugitani M, Aizawa S …

J Nihon Univ Med Ass., 70(2) 112-115, 2011
Attenuated immunochemotherapy for diffuse large B-cell lymphoma.

TAKEUCHI Jin, Miura K, Kobayashi Y, Hojo A, Hatta Y, Takeuchi J

Lancet Oncology., 12(8) 725, 2011
Helicobacter pylori Upregulates Peripheral Platelet Counts Mainly in Female Patients

Yoshihiro Matsukawa, Noboru Kitamura, Maho Iwamoto, Kimitoshi Kato, Shigeaki Mizuno, Yasuhiro Gon, Natalia Shirinskaya, Jin Takeuchi, Shigemasa Sawada

ACTA HAEMATOLOGICA, 126(3) 172-175, 2011
Epstein-Barr Virus Induces Erosive Arthritis in Humanized Mice.

TAKEUCHI Jin, Kuwana Y, Takei M, Yajima M, Imadome K, Inomata H, Shiozaki M, Ikumi N, Nozaki T, Shiraiwa H …

PLoS ONE., 2011(6) e26630, 2011
A case of aggressive myeloma recognized shortly after the remission following high-dose chemotherapy with autologous peripheral blood stem cell transplantation

Kaname Ueda, Katsuhiro Miura, Yoshihiro Hatta, Sumiko Kobayashi, Toshitake Tanaka, Atsuko Hojo, Hikaru Ishizuka, Umihiko Sawada, Yoshimasa Kura, Jin Takeuchi

INTERNATIONAL JOURNAL OF HEMATOLOGY, 92(3) 531-534, Oct, 2010
Intensified consolidation therapy with dose-escalated doxorubicin did not improve the prognosis of adults with acute lymphoblastic leukemia: the JALSG-ALL97 study

Itsuro Jinnai, Tohru Sakura, Motohiro Tsuzuki, Yasuhiro Maeda, Noriko Usui, Masayuki Kato, Hirokazu Okumura, Taiichi Kyo, Yasunori Ueda, Yuji Kishimoto …

INTERNATIONAL JOURNAL OF HEMATOLOGY, 92(3) 490-502, Oct, 2010

Books and Other Publications

日本血液学会編血液専門医テキスト

竹内仁 (Role: Joint author, 急性リンパ性白血病(Pｈ染色体陽性急性リンパ性白血病を除く）。)

南江堂, 2015
急性リンパ性白血病(Pｈ染色体陽性急性リンパ性白血病を除く）日本血液学会編血液専門医テキスト

南江堂, 2011
ALLの化学療法木崎昌弘編白血病・リンパ腫・骨髄腫第4版

中外医学社, 2011
急性リンパ性白血病血液疾患最新の治療2011-2013

南江堂, 2010
ALLの治療中，脳実質に径3cmの孤立性腫瘤が発見された．さてどうしよう？。造血器腫瘍治療これは困ったぞ，どうしよう！第２版。

中外医学社, 2010
ALLが再発した．さてどうしよう？。造血器腫瘍治療これは困ったぞ，どうしよう！第２版。

中外医学社, 2010
代表的なレジメン白血病今いちばん新しいがん治療・ケア実践ガイド

照林社, 2009
急性リンパ性白血病の治療プロトコール初発例の治療プロトコール。白血病治療マニュアル改訂第3版

南江堂, 2009
中枢神経系白血病の予防と治療。白血病治療マニュアル改訂第3版

南江堂, 2009
Ph陰性ALLに対する化学療法は？ EBM血液疾患の治療2010-2011

中外医学社, 2009
急性リンパ性白血病血液疾患診療ハンドブック -診療の手引きと臨床データ集- 改定版

医薬ジャーナル社, 2009
急性リンパ性白血病。吉田彌太郎編血液疾患ハンドブック－日常診療の手引きと臨床データ集－

医薬ジャーナル社, 2005
CNS白血病。大野竜三、宮脇修一編みんなに役立つ白血病の基礎と臨床

医薬ジャーナル社, 2004
成人ALL第一寛解期の化学療法

EBM血液疾患の治療治療 2003-2004。中外医学社, 2002
急性リンパ性白血病（ALL）

白血病・悪性リンパ腫治療プロトコール集。医薬ジャーナル社, 2001
血液

内科学エッセンス2 循環系血液, 1999
白血病の治療

貧血・出血傾向・白血病の診断と治療真興交易医書出版部, 1998
中枢神経浸潤の治療

造血器腫瘍における薬剤の便り方合理的投与法と展望医薬ジャーナル社, 1998
ビンクリスチンと末梢神経障害

この薬のこの副作用医歯薬出版, 1996
葉酸・プリン拮抗物質

Medical Practice 編集委員会編文光堂治療薬ガイド'94, 1994

Presentations

249

急性骨髄性白血病患者における亜ヒ酸代謝の検討。

竹内仁

第23回日本微量元素学会学術集会, Jul, 2012 Invited
An Intensified Consolidation Program with Dose-Escalated Doxorubicin for Newly Diagnosed Acute Lymphoblastic Leukemia (ALL): A Study by the Japan Adult Leukemia Study Group (JALSG ALL97 study).

TAKEUCHI Jin

he 51th Annual Meeting of American Society of Hematology., Dec, 2009
Comparison of Allogeneic Hematopoietic Cell Transplantation and Chemotherapy as Post-Remission Strategy in Elderly Patients with Non-M3 AML in CR1: Retrospective Analysis with 1036 Patients.

TAKEUCHI Jin

The 51th Annual Meeting of American Society of Hematology., Dec, 2009
A Markov Decision Analysis of Post-Remission Strategies in 2029 Patients with AML in First Remission (CR1): Should We Perform Allogeneic Hematopoietic Cell Transplantation in CR1?

TAKEUCHI Jin

The 51th Annual Meeting of American Society of Hematology., Dec, 2009
Prognostic Factor Among Elderly Patients with Diffuse Large B-Cell Lymphoma (DLBCL).

TAKEUCHI Jin

he 51th Annual Meeting of American Society of Hematology., Dec, 2009
The value of oral cytarabine ocfosfate and etoposide therapy for elderly high-risk MDS patients.

TAKEUCHI Jin

Oct 25, 2009
Multicenter retrospective analysis of initial treatment and transplantation for mantle cell lymphoma.

TAKEUCHI Jin

Oct 25, 2009
ABVD and involved field irradiation for Hodgkin Lymphoma; Japanese single center’s outcome.

TAKEUCHI Jin

Oct 25, 2009
Charlson Comorbidity Index is independent prognostic factor in elderly patients with DLBCL.

TAKEUCHI Jin

Oct 25, 2009
Nation-wide survey of allogeneic HCT and chemotherapy in elderly patients with AML in CR1.

TAKEUCHI Jin

Oct 24, 2009
肥満とAPLの予後。

竹内仁

第71回日本血液学会総会, Oct 24, 2009
骨融解と高カルシウム血症を伴うDLBCL症例における破骨細胞活性化因子(MIP)の発現。

竹内仁

第71回日本血液学会総会, Oct 23, 2009
皮膚限局の再発を認めた中枢神経原発悪性リンパ腫の一例。

竹内仁

第71回日本血液学会総会, Oct 23, 2009
Possibility of new cell therapy using self platelet-rich-plasma(PRP) for tissue repair.

TAKEUCHI Jin

Oct 23, 2009
JALSG AML97登録症例における高リスク群染色体異常の解析。

竹内仁

第7回日本臨床腫瘍学会学術集会, Mar 20, 2009
R-double CHOP療法で治療したmantle cell lymphomaの3例。

竹内仁

第24回悪性リンパ腫治療研究会, Mar 14, 2009
未治療マントル細胞リンパ腫に対する化学療法及び自家末梢血幹細胞移植の実態調査。

竹内仁

第24回悪性リンパ腫治療研究会, Mar 14, 2009
骨髄移植後に発症した異常フィブリノゲンによると思われる偽性高FDP血症の2例。

竹内仁

第31回日本造血細胞移植学会総会, Feb, 2009
汎血球減少を示したパルボウイルス感染症

竹内仁

第70回日本血液学会総会, Oct, 2008
亜ヒ酸使用後にauto PBSCTを行った再発APL３例

竹内仁

第30回日本造血細胞移植学会総会, Feb, 2008

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