J-GLOBAL         Last updated: Oct 2, 2019 at 02:50
Nihon University
School of Medicine, Department of Medicine, -
Job title
Research funding number


Dr. Satoshi Hayakawa graduated Nihon University school of medicine and obtained M.D. in 1983. After 3 years clinical training in Nihon University Itabashi Hospital, he studied reproductive genetics with the late Dr. Susumu Ohno and molecular immunology with the late Dr. Takeshi Matsunaga at the Beckman Research institute of the City of Hope Medical Center, California from 1985 to 1986. Returning Japan, he obtained PhD. from Nihon University and has been studied at department of Obstetrics and Gynecology and Pathology in Nihon University as well as at the National Institute of Infectious Diseases. From 2007, he is a professor of Microbiology and Infectious disease control and Clinical Immunology. He has a wide range of research themes such as mucosal immunity in female reproductive organs, cancer immunology, evolutionary medicine as well as pathography of famous musicians, artists and monarchs. For the first time, he discovered extra-thymic T cell differentiation in human decidual tissues and characterized their regulatory nature. He also reported an association between genetic polymorphism in class II HLA and TCR repertoire and susceptibility to inflammatory bowel diseases, he disproved an established theory of Th2 predominance in mammalian pregnancy. He published over 100 refereed articles in English. For the past few years, he is concentrated in research of the mechanisms of vertical HIV transmission and involvement of local immune systems as well as molecular epidemiology of pediatric viral infections and mass immune status of south east Asian children.

Research Areas


Academic & Professional Experience

ポストドクトラルフェロー, 生殖遺伝学部門(大野乾研究室), Beckman Research Institute of the City of Hope. Post Doctoral Fellow
Apr 1987
Mar 1988
医長, 産婦人科, 横須賀市立市民病院
Apr 1988
Mar 1991
助手(無給), 産婦人科学教室, Reseach fellow,Department of Obstetrics and Gynaecology,Nihon University School of Medicine
Apr 1991
Nov 1995
助手(有給), 産婦人科学教室, Reseach fellow,Department of Obstetrics and Gynaecology,Nihon University School of Medicine
Dec 1995
Jan 2004
講師(専任扱), 産婦人科学教室, Assstant Professor, Department of Obstetrics and Gynaecology ,Nihon University School of Medicine


医学, Faculty of Medicine, Nihon University
外科系産婦人科学, Graduate School, Division of Medicine, Nihon University

Committee Memberships

Dec 2009
Nov 2012
American Society of Reproductive Immunology  Vice President

Awards & Honors


Published Papers

Komine-Aizawa S, Jiang J, Mizuno S, Hayakawa S, Matsuo K, Boyd LF, Margulies DH, Honda M.
Eur J Immunol.   49(9) 1399-1414   Sep 2019
Determining effectiveness of rotavirus vaccine by immunochromatography and reverse transcriptase polymerase chain reaction: A comparison.Hoque SA, Iizuka I, Kobayashi M, Takanashi S, Anwar KS, Islam MT, Hoque SA, Khamrin P, Okitsu S, Hayakawa S, Ushijima H.
Vaccine.   37 5886-5890   Sep 2019   [Refereed]
Pham NTK, Thongprachum A, Shimizu Y, Trinh QD, Okitsu S, Komine-Aizawa S, Shimizu H, Hayakawa S, Ushijima H.
Infect Genet Evol.   75 104001   Aug 2019   [Refereed]
Kittigul L, Rupprom K, Che-Arsae M, Pombubpa K, Thongprachum A, Hayakawa S, Ushijima H.
J Appl Microbiol.   126(4) 1290-1301   Apr 2019   [Refereed]
Ishii W, Komine-Aizawa S, Takano C, Fujita Y, Morioka I, Hayakawa S.
Prim Care Companion CNS Disord.   21(2)    Apr 2019


Takada K, Komine-Aizawa S, Kuramochi T, Ito S, Trinh QD, Pham NTK, Sasano M, Hayakawa S.
Am J Reprod Immunol.   e13027.   Aug 2018   [Refereed]
Trinh QD, Pham NT, Fuwa K, Takada K, Komine-Aizawa S, Honda M, Ushijima H, Hayakawa S.
Clin Lab.   62(12) 2305-2311.-36   Dec 2016   [Refereed]
Tran DN, Trinh QD, Pham NT, Vu MP, Ha MT, Nguyen TQ, Okitsu S, Hayakawa S, Mizuguchi M, Ushijima H.
Epidemiol Infect.   144(3) 527-36   Feb 2016   [Refereed]
Immune responses against norovirus GII.4 virus-like particles in mice.
Ushijima H, Machida S, Nomura A, Khamrin P, Tran DN, Nomura H, Hayakawa S.
Acta Virol.   60(4) 339-346   2016   [Refereed]
Ishii W, Komine-Aizawa S, Hayakawa S.
J Clin Psychiatry.   77(12) e1653   Dec 2016   [Refereed]

Books etc

実践 臨床生殖免疫学
編者 柴原浩章 (Part:Joint Work, I総論 3.感染免疫、II各論 5.妊娠と免疫- 8 歯周病、6.感染症と免疫-2-妊娠と感染症⑧HIV・AIDS)
中外医学社   May 2018   ISBN:978-4-498-06088-3
標準微生物学 第13版
監修:中込 治、編集:神谷 茂、錫谷達夫 (Part:Joint Work, 第VI編ウイルス学各論 第33章D パピローマウイルス科、Eポリオーマウイルス科 )
医学書院   Mar 2018   ISBN:978-4-260-03456-2
監修 猿田享男 北村惣一郎 (Part:Joint Work, §20婦人科疾患 2.卵巣・卵管・骨盤 §20-11子宮付属器炎:骨盤内炎症性疾患)
日本医事新報社   Jul 2017   ISBN:978-4-7849-4650-1
今日の治療指針 2017
福井次矢、高木 誠、小室一成 総編集 (Part:Joint Work, 妊娠と感染症)
医学書院   Jan 2017   ISBN:978-4-260-02809-7
早川 智、山口陽子 (Part:Joint Work)
人間と歴史社   Nov 2016   ISBN:978-4-89007-205-7

Conference Activities & Talks

教育講演34 医学史から見た感染症 [Invited]
早川 智
第93回日本感染症総会・学術講演会   6 Apr 2019   日本感染症学会
LAMP法によるβ-lactamase遺伝子(OXA-48)検出-グラム陰性菌臨床分離株への応用― [Invited]
第93回日本感染症総会・学術講演会   5 Apr 2019   日本感染症学会
LAMP法によるβ-lactamase遺伝子(GES)検出2-GES型カルバペネマーゼ遺伝子の検出ー [Invited]
第93回日本感染症総会・学術講演会   5 Apr 2019   日本感染症学会
LAMP法による肺炎球菌莢膜型の同定2 [Invited]
第93回日本感染症総会・学術講演会   4 Apr 2019   日本感染症学会
西村光司, Aksara Thongprachum, 沖津 祥子, 早川 智, 高橋昌里, 牛島 廣治
第回日本小児栄養消化器肝臓学会   2018   

Teaching Experience


Research Grants & Projects

Project Year: 2014 - 2015    Investigator(s): 早川智
Project Year: 2008 - 2010    Investigator(s): 齋藤滋