Masatake ASANO

Profile Information

Affiliation: Professor, School of Dentistry Department of Dentistry -, Nihon University

Other name(s) (e.g. nickname): Masatake Asano
Researcher number: 10231896
J-GLOBAL ID: 200901016732064828
researchmap Member ID: 1000085536

Research Interests

Research Areas

Research History

Apr, 2015 - Present

教授, 病理学講座, 日本大学歯学部
Oct, 2009 - Present

Associate professor
May, 2004 - Sep, 2009

日本大学歯学部専任講師

Education

Committee Memberships

Awards

Nov, 2013

佐藤賞, 電解酸性機能水の生物学的機能, 日本大学歯学部同窓会

Papers

Allograft inflammatory factor-1 released from the cerebral microglia affect several organs in the body

Mai Fukasawa, Kensuke Nishio, Daichi Oikawa, Tomoka Itou, Toshimitsu Iinuma, Masatake Asano

Journal of Molecular Histology, 54(2) 147-156, Mar 6, 2023
Effectiveness of Acid-electrolyzed Functional Water for Mouth Wash: An In Vitro Study.

Daichi Oikawa, Kensuke Nishio, Muneaki Tamura, Mai Fukasawa, Takamasa Yoshida, Shinji Okada, Tomoka Ito, Mariko Tsunoda, Masatake Asano, Toshimitsu Iinuma

In vivo (Athens, Greece), 36(5) 2211-2217, 2022
Bactericidal and cytotoxic effects of acid-electrolyzed functional water.

Okamura T, Tamura M, Suguro H, Ohtsu M, Omagari D, Yoshino A, Ogiso B, Asano M.

Journal of Oral Science, 2020 Peer-reviewedCorresponding author
Ouabain signaling in oral squamous cell carcinoma cells.

Saito S, Ohtsu M, Asano M, Ishigami T.

Journal of Oral Science, 2020 Peer-reviewedCorresponding author
Nickel chloride administration prevents the growth of oral squamous cell carcinoma.

Hirotaka Ota, Takashi Shionome, Hisashi Suguro, Satsuki Saito, Kosuke Ueki, Yoshinori Arai, Masatake Asano

Oncotarget, 2018 Peer-reviewedCorresponding author
Rapid detection of Candida albicans in oral exfoliative cytology samples by loop-mediated isothermal amplification

Hiroyasu Noguchi, Takashi Iwase, Daisuke Omagari, Masatake Asano, Ryota Nakamura, Kosuke Ueki, Keiji Shinozuka, Tadayoshi Kaneko, Morio Tonogi, Hiderou Ohki

Journal of Oral Science, 59(4) 541-547, 2017 Peer-reviewed
Functional expression of BMP7 receptors in oral epithelial cells. Interleukin-17F production in response to BMP7

Kensuke Nishio, Yasumasa Ozawa, Hisanori Ito, Takashi Kifune, Tatsuya Narita, Toshimitsu Iinuma, Nobuhito Gionhaku, Masatake Asano

JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, 37(5) 515-521, 2017 Peer-reviewed
EMMPRIN Inhibits bFGF-Induced IL-6 Secretion in an Osteoblastic Cell Line, MC3T3-E1

Akari Saiki, Mitsuru Motoyoshi, Keiko Motozawa, Teinosuke Okamura, Kousuke Ueki, Noriyoshi Shimizu, Masatake Asano

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 14(12) 1173-1180, 2017 Peer-reviewed
Effects of bittern water on cariogenic bacteria and saliva secretion

Mariko Ohtsu, Muneaki Tamura, Hideto Sasaki, Shuichi Sato, Masatake Asano

Journal of Oral Science, 59(3) 453-456, 2017
Diverse calcification patterns of ameloblastic fibro-odontoma on radiographic examination

Masao Araki, Shunsuke Namaki, Toshihiko Amemiya, Kunihito Matsumoto, Kazuya Honda, Yoshiyuki Yonehara, Naoyuki Matsumoto, Masatake Asano

JOURNAL OF ORAL SCIENCE, 58(4) 533-537, Dec, 2016 Peer-reviewed
Inhibition of epithelial-mesenchymal transition by cetuximab via the EGFR-GEP100-Arf6-AMAP1 pathway in head and neck cancer.

Matsumoto Y, Sakurai H, Kogashiwa Y, Kimura T, Matsumoto Y, Shionome T, Asano M, Saito K, Kohno N.

Head and Neck, Nov 3, 2016 Peer-reviewed
Loop-mediated isothermal amplification combined with PCR and immunohistochemistry for detecting Porphyromonas gingivalis in periapical periodontitis

Taiichi Kitano, Yoshikazu Mikami, Takashi Iwase, Masatake Asano, Kazuo Komiyama

JOURNAL OF ORAL SCIENCE, 58(2) 163-169, Jun, 2016 Peer-reviewed
Functional expression of TLR5 in murine salivary gland epithelial cells.

Iwasa S, Ota H, Nishio K, Ohtsu M, Kusunoki M, Gojoubori T, Shirakawa T, Asano M.

Journal of Oral Science, 58(3) 317-323, Feb 20, 2016 Peer-reviewedCorresponding author
Electrolytically generated acid functional water inhibits NF-kappa B activity by attenuating nuclear-cytoplasmic shuttling of p65 and p50 subunits

Takahiro Gojoubori, Hirotaka Ota, Masafumi Kusunoki, Yukina Nishio, Kensuke Nishio, Satoko Iwasa, Yasuhide Kaneko, Masatake Asano

JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, 36(3) 248-253, 2016 Peer-reviewed
Comparison of MMP2 and MMP9 expression levels between primary and metastatic regions of oral squamous cell carcinoma

Kensuke Nishio, Keiko Motozawa, Daisuke Omagari, Takahiro Gojoubori, Takayuki Ikeda, Masatake Asano, Nobuhito Gionhaku

Journal of Oral Science, 58(1) 59-65, 2016 Peer-reviewed
Cancer cell-derived IL-8 induces monocytic THP1 cells to secrete IL-8 via the mitogen-activated protein kinase pathway

Yukina Nishio, Takahiro Gojoubori, Yasuhide Kaneko, Noriyoshi Shimizu, Masatake Asano

TUMOR BIOLOGY, 36(12) 9171-9177, Dec, 2015 Peer-reviewed
Osteogenic Gene Transcription Is Regulated via Gap Junction-Mediated Cell-Cell Communication

Yoshikazu Mikami, Kiyofumi Yamamoto, Yuko Akiyama, Masayuki Kobayashi, Eri Watanabe, Nobukazu Watanabe, Masatake Asano, Noriyoshi Shimizu, Kazuo Komiyama

STEM CELLS AND DEVELOPMENT, 24(2) 214-227, Jan, 2015 Peer-reviewed
Pigmented oral carcinoma in situ: a case report and literature review

Naoyuki Matsumoto, Taiichi Kitano, Hidero Oki, Daisuke Omagari, Yasuyoshi Matsue, Michisato Okudera, Takashi Yamamura, Yohichi Nishikawa, Satoshi Nishimura, Masatake Asano …

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, 118(3) E79-E83, Sep, 2014 Peer-reviewed
Distinct signaling pathways leading to the induction of human beta-defensin 2 by stimulating an electrolyticaly-generated acid functional water and double strand RNA in oral epithelial cells

Takahiro Gojoubori, Yukina Nishio, Masatake Asano, Tetsuya Nishida, Kazuo Komiyama, Koichi Ito

JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, 34(2) 97-103, Apr, 2014
Nickel ion inhibits nuclear factor-kappa B activity in human oral squamous cell carcinoma.

Shionome et al.

PLOS One, Sep, 2013 Peer-reviewedCorresponding author

Misc.

Establishment of enzyme-linked immunosorbent assay system against propiece interleukin-1 α

Eri Sata, Leo Takada, Ryo Kaetsu1, Mai Fukasawa, Mariko Ohtsu, Mitsuru Motoyoshiand Masatake Asano

Journal of Oral Science, Jan 1, 2021 Peer-reviewedCorresponding author
Establishment of enzyme-linked immunosorbent assay system against propiece interleukin-1 α

Eri Sata, Leo Takada, Ryo Kaetsu1, Mai Fukasawa, Mariko Ohtsu, Mitsuru Motoyoshiand Masatake Asano

Journal of Oral Science, Dec, 2020 Peer-reviewedCorresponding author
Bone regeneration is enhanced by the combined use of acid-electrolyzed functional water with hydroxyapatite/collagen composite

Yasumasa Ozawa, Takahiro Gojoubori, Hirotaka Ota, Shuichi Sato and, Masatake Asano

Journal of Biomedical Materials Research B Applied Biomaterials. PMID: 31820853, Sep 1, 2020 Peer-reviewedCorresponding author
Comparison of the bone augmentation ability of absorbable collagen sponge with that of hydroxyapatite/collagen composite.

Ozawa Y, Kubota T, Yamamoto T, Tsukune N, Koshi R, Nishida T, Asano M, Sato S

Journal of Oral Science, 48回 12-12, Sep, 2018 Peer-reviewed
Acid-electrolyzed functional water induces the secretion of extracellular matrix metalloproteinase inducer.

Kusunoki M, Sata E, Nishio K, Tanaka T, Nishida T, Sugano N, Sato S, Asano M.

International Journal of Medical Sciences, 2018 Peer-reviewedCorresponding author
Functional comparison of high and low molecular weight basic fibroblast growth factors.

Motozawa K, Motoyoshi M, Saiki A, Sasaki H, Shimizu N, Asano M.

Journal of Cellular Biochemistry, 2018 Peer-reviewedCorresponding author
A case of basal cell adenoma in the buccal mucosa

62(8) 409-413, Aug, 2016
Nicotine-Mediated Ca2+-Influx Induces IL-8 Secretion in Oral Squamous Cell Carcinoma Cell

Kou Tsunoda, Ichiro Tsujino, Ryosuke Koshi, Naoyuki Sugano, Shuichi Sato, Masatake Asano

JOURNAL OF CELLULAR BIOCHEMISTRY, 117(4) 1009-1015, Apr, 2016 Peer-reviewed
Toll-like receptor 4 signaling in trigeminal ganglion neurons contributes tongue referred pain associated with tooth pulp inflammation

Kinuyo Ohara, Kohei Shimizu, Shingo Matsuura, Bunnai Ogiso, Masatake Asano, Yoshiyuki Tsuboi, Masamichi Shinoda, Koichi Iwata

JournalNeuroinflammation, 10:139, Nov 23, 2013 Peer-reviewed
Nicotine-induced expression of low-density lipoprotein receptor in oral epithelial cells.

Ito et al.

PLOS One, Nov, 2013 Peer-reviewedCorresponding author

Books and Other Publications

みて学ぶ口腔病理学第3版

日本大学歯学部病理学講座, 浅野正岳他 (Role: Joint author) (Original Author(s): 日本大学歯学部病理学講座浅野正岳他)

砂書房, Oct, 2019
新口腔病理学

高田隆ほか (Role: Contributor) (Original Author(s): 高田隆ほか)

医歯薬出版, 2018
新スタンダード口腔病理学

槻木恵一, 岡田康男ほか (Role: Joint author) (Original Author(s): 槻木恵一、岡田康男ほか)

学研書院, 2017
病理学総論にもとづく口腔病理学

井上孝, 田中昭男, 長谷川博雅ほか (Role: Contributor) (Original Author(s): 井上孝、田中昭男、長谷川博雅ほか)

永末書店, 2017

Presentations

酸性電解機能水の創傷治癒促進メカニズム

浅野正岳

第16回日本機能水学会, Nov 18, 2017, 日本機能水研究財団 Invited
新しい根管清掃・消毒法に関する基礎的研究

岡村貞之介、五條堀孝廣、勝呂尚、田村宗明、浅野正岳、小木曽文内

日本機能水学会, Sep 11, 2016, 日本機能水財団
電解酸性機能水の生物学的機能

浅野正岳

日本口腔機能水学会, Mar, 2015 Invited
電解酸性機能水の生物学的機能

浅野正岳

第15回日本口腔機能水学会学術大会, Mar 23, 2014, 日本口腔機能水学会 Invited
Production of type III IFNs by rotavirus infected intestinal epithelial cells

Omagari D, Gojoubori T, Komiyama K

The 12th International symposium on double-stranded RNA viruses, Nov 30, 2012
電解酸性機能水は口腔上皮におけるニコチン誘導性LDLR発現を抑制する

五條堀孝廣、伊藤聖、尾曲大輔、西田哲也、小宮山一雄、伊藤公一

第１１回日本機能水学会学術大会, Oct 21, 2012
Rotavirus and type III Interferon

15th International Congress of Mucosal Immunology, Jul, 2011
ロタウイルス感染とtype IIIインターフェロン産生

浅野正岳、尾曲大輔、小宮山一雄

日本大学学部連携シンポジウム, Dec, 2010
Production of type III IFNs in rotavirus infected intestinal epithelial cells.

Masatake Asano, Daisuke Omagari, Itaru Moro, Kazuo Komiyama

International Congress of Immunology, Aug, 2010, American and Japanese Society of Immunology
ロタウイルス非構造タンパク質NSP1の検出法の開発とその応用

浅野正岳、尾曲大輔、砂川恵伸、茂呂周、小宮山一雄

日本消化器免疫学会, Jul, 2010
Rotavirus infection and host immune system

Masatake Asano, Daisuke Omagari, Itaru Moro, Kazuo Komiyama

Japanese Associstion of Food Immunology, May, 2010
DSS腸炎におけるマウス多量体免疫グロブリンレセプター量の変化

日本大学先端バイオフォーラム, Apr, 2010
Double-stranded RNA induced expression of ICAM-1 in HT-29 cells.

Daisuke Omagari

Japanese Society of Mucosal Immunology, Jul 23, 2009
A Better Understanding of the Mechanisms by which Rotavirus Escape the Host Defense System.

43rd US-Japan joint meeting on viral diseases, Jul 22, 2009
Differential distribution of mpIgR in mouse organs.

Daisuke Omagari, Megumi Iijima, Itaru Moro, Kazuo Komiyama

14th International congress of mucosal immunology 2009, Jul 10, 2009
Human beta-defensin-2 can inhibit the infection of rotavirus in HT-29 cells.

Osamu Nakagomi

42nd US-Japan joint meeting on viral diseases., May, 2008
Ionomycin inhibited the ER-Golgi transport of pIgR.

Itaru Moro, Kazuo Komiyama

13th International Congress of Mucosal Immunology, Jul, 2007
Ionomycinによるpolymeric immunoglobulin receptor (pIgR)のER-Golgi間輸送の阻害

藤岡隼、勝呂尚、馬谷原琴江、茂呂周、小宮山一雄

第42回日本消化器免疫学会, Aug 4, 2005
Modulation of pERK expression in medulla and upper cervical cord after capsaicin treatment of the rat tooth pulp

Kohei Shimizu, Junichi Kitagawa, Bunnai Ogiso, Koichi Iwata

The 82 nd Annual Meeting of the phisiological society of Japan, May 18, 2005
分泌型IgAによる生体防御

第94回日本病理学会総会, Apr 14, 2005

Professional Memberships

Research Projects

脳神経外科手術におけるb-FGF徐放化光ゲル化剤の有用性の検証と開発

科学研究費助成事業, 基盤研究(C), 日本学術振興会, Apr, 2022 - Mar, 2025

大谷直樹, 浅野正岳, 櫛引俊宏, 石原美弥, 吉野篤緒
電解酸性機能水の超高齢者への含嗽剤としての実用化に関する研究

科学研究費助成事業, 基盤研究(C), 日本学術振興会, Apr, 2020 - Mar, 2023

浅野正岳, 西尾健介
性差による舌痛症発生機構の違いについての基礎研究

科学研究費助成事業, 基盤研究(C), 日本学術振興会, Apr, 2020 - Mar, 2023

坪井美行, 浅野正岳, 三枝禎
Basic research on a treatment for pain targeting primary afferent A nerve fibers

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2020

TSUBOI Yoshiyuki
Ni2+イオンによる口腔癌治療の可能性に関する研究

基盤研究（Ｃ）, Apr, 2017 - Mar, 2020
電解酸性機能水の創傷治癒の促進効果に関する研究

基盤研究（Ｃ）, Apr, 2017 - Mar, 2020
Involvement of epigenetic regulatory factors in respiration and swallowing during the suckling period

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

SHIRAKAWA Tetsuo, TAKEI Hiroki, ISHIYAMA Misa
Involvoment of satellite glial cells in trigeminal ganglion in tongue pain

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2015

SHINODA Masamichi, IWATA Koichi, ASANO Masatake, TANABE Natsuko, SUZUKI Ikuko, HONDA Kuniya, OMAGARI Daisuke
Investigation of the epigenetic mechanism of swallowing and respiratory disturbances

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2011 - 2013

SHIRAKAWA Tetsuo, ASANO Masatake, SAIGUSA Tadashi
Rotavirus infection to oral epithelial cells

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2011 - 2013

ASANO Masatake
Characterization of human dental pulp-derived cell lines

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2006 - 2008

SUGURO Hisashi, ASANO Masatake
The duration analysis of the experimental rabbit temporomandibular joint inflammation by the X ray in vivo micro CT for high-speed high resolution animals

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2006 - 2007

HONDA Kazuya, ARAI Yoshinori, OHSHIMA Mitsuhiro, ASANO Masatake, KAWASHIMA Shoji, EJIMA Ken-ichiro
Development and analysis of secretory component disrupted mouse

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, 1997 - 1999

MORO Itaru, SATO Kahei, OHKUBO Nobuko, IWASE Takashi, KAI Osamu, ASANO Masatake
A study on the expression of cytokines in epithelial cells stimulated with LPS.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 1995 - 1996

KUDO Itsuro, ASANO Masatake, MORO Itaru, ODA Yasuyuki, IWANARI Shinkichi
電解酸性機能水の生物学的機能

Grant-in-Aid for Co-operative Research (A)

浅野正岳

Social Activities

お口の中にできる”がん”ってどんな病気？

Lecturer

日本大学歯学部, Nov 4, 2017 - Present

Profile Information

Research Interests

Research Areas

Research History

Education

Committee Memberships

Awards

Papers

Misc.

Books and Other Publications

Presentations

Professional Memberships

Research Projects

Social Activities

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