2006年
Extracellular enzymatic activities in Cryptococcus neoformans strains isolated from AIDS patients in different countries
Revista Iberoamericana de Micologia
- ,
- ,
- ,
- ,
- ,
- ,
- 巻
- 23
- 号
- 4
- 開始ページ
- 216
- 終了ページ
- 220
- 記述言語
- 英語
- 掲載種別
- 出版者・発行元
- Asociacion Espanola de Micologia
Three hundred and ten Cryptococcus neoformans strains isolated from AIDS patients in five different countries (151 from Brazil, 23 from Italy, 28 from Spain, 104 from Thailand and four from Turkey) were tested by the API-ZYM kit to detect their extracellular enzymatic activity. The enzymes esterase (C4) (n°3), esterase lipase (C8) (n°4), leucine arylamidase (n°6) and acid phosphatase (n°11) were commonly positive in most of the strains (more than 95%). These enzymes could be considered a useful tool not only for C. neoformans identification, but in particular for their possible relationship to new C. neoformans virulence factors and also for epidemiological research. Interestingly, it is also the high positive percentage of α-glucosidase and β-glucosidase detected in all isolates. The serotype A was the most predominant serotype in all countries, except for Italy where the serotype D was predominant. Further studies are needed to draw a clear correlation between the API-ZYM profile and serotype. ©2006 Revista Iberoamericana de Micología.
- リンク情報
- ID情報
-
- ISSN : 1130-1406
- PubMed ID : 17388645
- SCOPUS ID : 33750940775