Shinichi Watanabe

Profile Information

Affiliation: Teikyo University Faculty of Medicine, Department of Medicine, Departmet of Dermatology

Degree: (BLANK)

J-GLOBAL ID: 200901005121283000

Research Interests

Research Areas

Life sciences / Dermatology /

Research History

1985 - 1988

米国ハーバード大マサチューセツ総合病院皮膚科
1985 - 1988

Research fellow, Department of Dermatology,
リサーチ・フェロー
Medical School
Massachusetts General Hospital, Harvard

Education

- 1978

The University of Tokyo Faculty of Medicine
- 1978

The University of Tokyo Faculty of Medicine

Committee Memberships

Misc.

125

Interleukin-8 and tumor necrosis factor alpha production in human epidermal keratinocytes induced by Trichophyton mentagrophytes

Y Nakamura, R Kano, A Hasegawa, S Watanabe

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY 9(4) 935 - 937 Jul, 2002
Interleukin-8 and tumor necrosis factor alpha production in human epidermal keratinocytes induced by Trichophyton mentagrophytes

Y Nakamura, R Kano, A Hasegawa, S Watanabe

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY 9(4) 935 - 937 Jul, 2002
Syringoid eccrine carcinoma. Report of a case with immunohistochemical analysis of cytokeratin expression.（共著）

Am J Dermatopathol 24(5):409-13 2002
Ketoconazole suppresses interleukin-4 plus anti-CD40-induced IgE class switching in surface IgE negative B cells from patients with atopic dermatitis.（共著）

J Invest Dermatol 119:590-599 2002
Molecular identification of Trichophyton rubrum isolate from a dog by chitin synthase I (CHSI) gene analysis.（共著）

Med Mycol. 40: 439-442 2002
Differentiation of Malassezia furfur and Malassezia sympodialis by glycine utilization. （共著）

Mycoses. 45 (5-6): 180-3 2002
The skin fungus-induced Th1- and Th2-related cytokine, chemokine and prostaglandin E2 production in peripheral blood mononuclear cells from patients with atopic dermatitis and psoriasis vulgaris.

Clin Exp Allergy（共著） 32(8):1243-50 2002
Ketoconazole suppresses prostaglandin E2-induced cyclooxygenase-2 expression in human epidermoid carcinoma A-431 cells

Naoko Kanda, Shinichi Watanabe

Journal of Investigative Dermatology 119(1) 174 - 181 2002
Characterization of a monoclonal antibody against desmoplakin 1 for use in dogs.（共著）

Vet Dermatol 13: 165-167 2002
Homogeneous cell suspension of Malassezia pachydermatis obtained with an ultrasonic homogenizer.（共著）

J Vet Med. Sci 64 (4): 381-383 2002
Case report. First report on human ringworm caused by Arthroderma benhamiae in Japan transmitted from a rabbit

Y. Nakamura, R. Kano, E. Nakamura, K. Saito, S. Watanabe, A. Hasegawa

Mycoses 45(3-4) 129 - 131 2002
17b-estradiol enhances vascular endothelial growth factor production and dihydrotestosterone antagonizes the enhancement via the regulation of adenylate cyclase in differentiated THP-1 cells.（共著）

J Invest Dermatol 118: 519-529 2002
Immunohistochemical analysis of cytokeratin and human milk fat globulin expression in mucinous carcinoma of the skin.（共著）

J Cutan Pathol 29: 38-43 2002
Syringoid eccrine carcinoma. Report of a case with immunohistochemical analysis of cytokeratin expression.（共著）

Am J Dermatopathol 24(5):409-13 2002
Ketoconazole suppresses interleukin-4 plus anti-CD40-induced IgE class switching in surface IgE negative B cells from patients with atopic dermatitis.（共著）

J Invest Dermatol 119:590-599 2002
Molecular identification of Trichophyton rubrum isolate from a dog by chitin synthase I (CHSI) gene analysis.（共著）

Med Mycol. 40: 439-442 2002
Differentiation of Malassezia furfur and Malassezia sympodialis by glycine utilization. （共著）

Mycoses. 45 (5-6): 180-3 2002
The skin fungus-induced Th1- and Th2-related cytokine, chemokine and prostaglandin E2 production in peripheral blood mononuclear cells from patients with atopic dermatitis and psoriasis vulgaris.

Clin Exp Allergy（共著） 32(8):1243-50 2002
Ketoconazole suppresses prostaglandin E2-induced cyclooxygenase-2 expression in human epidermoid carcinoma A-431 cells

Naoko Kanda, Shinichi Watanabe

Journal of Investigative Dermatology 119(1) 174 - 181 2002
Characterization of a monoclonal antibody against desmoplakin 1 for use in dogs.（共著）

Vet Dermatol 13: 165-167 2002
Homogeneous cell suspension of Malassezia pachydermatis obtained with an ultrasonic homogenizer.（共著）Sci

J Vet Med. 64 (4): 381-383 2002
Case report. First report on human ringworm caused by Arthroderma benhamiae in Japan transmitted from a rabbit

Y. Nakamura, R. Kano, E. Nakamura, K. Saito, S. Watanabe, A. Hasegawa

Mycoses 45(3-4) 129 - 131 2002
17b-estradiol enhances vascular endothelial growth factor production and dihydrotestosterone antagonizes the enhancement via the regulation of adenylate cyclase in differentiated THP-1 cells.（共著）

J Invest Dermatol 118: 519-529 2002
Immunohistochemical analysis of cytokeratin and human milk fat globulin expression in mucinous carcinoma of the skin.（共著）

J Cutan Pathol 29: 38-43 2002
Regulatory roles of adenylate cyclase and cyclic nucleotide phosphodiesterases 1 and 4 in interleukin-13 production by activated human T cells

N Kanda, S Watanabe

BIOCHEMICAL PHARMACOLOGY 62(4) 495 - 507 Aug, 2001
The effects of Malassezia yeasts on cytokine production by human keratinocytes

S Watanabe, R Kano, H Sato, Y Nakamura, A Hasegawa

JOURNAL OF INVESTIGATIVE DERMATOLOGY 116(5) 769 - 773 May, 2001
Case report. First isolation of Trichosporon domesticum from a cat.（共著）

Mycoses 44: 518-520 2001
Antimycotics suppress interleukin-4 and interleukin-5 production in anti-CD3 plus anti-CD28-stimulated T cells from patients with atopic dermatitis. （共著）

J Invest Dermatol 117 (6): 1635-1646 2001
Feline ubiquitin fusion protein gene.（共著）

Vet Res Commun 25 (8): 615-622 2001
Identification of Sporothrix schenckii based on sequences of the chitin synthase 1 gene.（共著）

Mycoses 44: 261-265 2001
Verruciform xanthoma. Report of a case with molecular biological analysis of HPV and immunohistochemical analysis of cytokeratin expression.（共著）

Clin Exp Dermatol 26 (8): 730-731 2001
Arthroderma benhamiae infection in a rabbit.（共著）

J Vet Med Sci 63 (8): 929-931 2001
Expression of the ubiquitin gene in Microsporum canis and Trichophyton mentagrophytes cultured with fluconazole.（共著）

Antimicrob Agents Chemother 45 (9): 2559-2562 2001
Gangliosides GD1b, GT1b, and GQ1b suppress the growth of human melanoma by inhibiting interleukin-8 production: The inhibition of adenylate cyclase.（共著）

J Invest Dermatol 117 (2): 284-293 2001
17b-estradiol, progesterone, and dihydrotestosterone suppress the growth of human melanoma by inhibiting interleukin-8 production.（共著）

J Invest Dermatol 117 (2): 274-283 2001
The genetic diversity of clinical isolates of M. pachydermatis from dogs and cats.（共著）

Med Mycol 39 (4): 329-334 2001
Case report. First isolation of Trichosporon domesticum from a cat.（共著）

Mycoses 44: 518-520 2001
Antimycotics suppress interleukin-4 and interleukin-5 production in anti-CD3 plus anti-CD28-stimulated T cells from patients with atopic dermatitis. （共著）

J Invest Dermatol 117 (6): 1635-1646 2001
Feline ubiquitin fusion protein gene.（共著）

Vet Res Commun 25 (8): 615-622 2001
Identification of Sporothrix schenckii based on sequences of the chitin synthase 1 gene.（共著）

Mycoses 44: 261-265 2001
Verruciform xanthoma. Report of a case with molecular biological analysis of HPV and immunohistochemical analysis of cytokeratin expression.（共著）

Clin Exp Dermatol 26 (8): 730-731 2001
Arthroderma benhamiae infection in a rabbit.（共著）

J Vet Med Sci 63 (8): 929-931 2001
Expression of the ubiquitin gene in Microsporum canis and Trichophyton mentagrophytes cultured with fluconazole.（共著）

Antimicrob Agents Chemother 45 (9): 2559-2562 2001
Gangliosides GD1b, GT1b, and GQ1b suppress the growth of human melanoma by inhibiting interleukin-8 production: The inhibition of adenylate cyclase

Naoko Kanda, Kenji Nakai, Shinichi Watanabe

Journal of Investigative Dermatology 117(2) 284 - 293 2001
17b-estradiol, progesterone, and dihydrotestosterone suppress the growth of human melanoma by inhibiting interleukin-8 production.（共著）

J Invest Dermatol 117 (2): 274-283, 2001
The genetic diversity of clinical isolates of M. pachydermatis from dogs and cats.（共著）

Med Mycol 39 (4): 329-334 2001
Immunohistochemical analysis of human milk fat globulin expression in extramammary paget's disease.（共著）

Clin Exp Dermatol. 26(2) 192 - 195 2001
Immunohistochemical analysis of human milk fat globulin 1 and cytokeratin expression in median raphe cyst on the penis.（共著）

Clin Exp Dermatol. 26(1) 88 - 92 2001
Intracellular 3', 5'-adenosine cyclic monophosphate level regulates house dust mite-induced interleukin-13 production by T cells from mite-sensitive patients with atopic dermatitis.（共著）

J Invest Dermatol 116 3 - 11 2001
Chitin synthase 1(Chs 1) gene sequences of Microsporum equinum and Trichophyton equinum.（共著）

Vet Microbiol. 78 85 - 90 2001
Gangliosides GD1b, GT1b, and GQ1b enhance IL-2 and IFN-g production and suppress IL-4 and IL-5 production in phytohemagglutinin-stimulated human T cells.（共著）

J Immunol 166 72 - 80 2001
prurigo pigmentosa associated with diabetic ketoacidosis.（共著）

Acta Dermato Venereol 80(6) 447 - 448 2000
Detection of Microsporum canis in the skin scrapings of dogs with dermatophytosis based on sequences of the chitin synthase 1 gene.（共著）

Microbiol Immunol 44(7) 605 - 607 2000
First isolation of Exophiala dermatitidis from a dog : identification by molecular analysis.（共著）

Vet Microbiol 76(2) 201 - 205 2000
Susceptibility testing of Malassezia species using the urea broth microdilution method.（共著）

Antimicrob Agents Chemother. 44(8) 2185 - 2186 2000
Ganglioside GD1a enhances immunoglobulin production by human peripheral blood mononuclear cells（共著）

Exp Hematol 20 672 - 679 2000
Ganglioside GQ1b enhances anti-double-stranded DNA antibody and IgG production of PBMCs from patients with systemic lupus erythematosus（共著）

J Allergy Clin Immunol 105(3) 532 - 540 2000
The use of cytokeratins 7 and 20 in the diagnosis of primary and secondary extramammary Paget's disease

T. Ohnishi, S. Watanabe

British Journal of Dermatology 142(2) 243 - 247 2000
Immunohistochemical analysis of cytokerain expression in reactive eccrine syringofibroadenoma-like lesion : a comparative study with eccrine syringofibroadenoma（共著）

J Cutan Pathol 27(4) 164 - 168 2000
Molecular analysis of CAP59 gene sequences from five serotypes of Cryptococcus neoformans（共著）

J Clin Microbiol 38(3) 992 - 995 2000
Difference of chitin synthase 1 (CHS1) gene sequences in Trichophyton rubrum and T. violaceum （共著）

Med Mycol 38(1) 47 - 50 2000
Species-specific primers of chitin synthase 1 gene for the differentiation of the Trichophyton mentagrophytes complex

R Kano, Y Nakamura, T Watari, S Watanabe, H Takahashi, H Tsujimoto, A Hasegawa

MYCOSES 42(1-2) 71 - 74 Apr, 1999
Immunohistochemical analysis of cytokeratin expression in multiple eccrine hidrocystoma

Takamitsu Ohnishi, Shinichi Watanabe

Journal of Cutaneous Pathology 26(2) 91 - 94 Feb, 1999
Molecular confirmation of a Trichophyton violaceum isolate from human black-dot ringworm

Ken Okabayashi, Rui Kano, Yuka Nakamura, Shiho Ooka, Masato Kashima, Masako Mizoguchi, Shinichi Watanabe, Atsuhiko Hasegawa

Mycopathologia 146(3) 127 - 130 1999
Phylogenetic relation of Epidermophyton floccosum to the species of Microsporum and Trichophyton in chitin synthase 1 (CHS1) gene sequences

R Kano, Y Nakamura, S Watanabe, H Tsujimoto, A Hasegawa

MYCOPATHOLOGIA 146(3) 111 - 113 1999
Characterization of the cyclophilin of Trichophyton mentagrophytes（共著）

Micobiol Immunol 44(1) 51 - 56 1999
Lack of evidence of human herpesvirus 8 DNA sequences in HIV-negative patients with systemic plasmacytosis（共著）

Br J Dermatol 141(5) 942 - 943 1999
Molecular heterogeneity in clinical isolates of Malassezia pachydermatis from dogs（共著）

Vet Microbiol 70 67 - 75 1999
Angioma serpiginosum : a report of two cases identified using epiluminescence microscopy（共著）

Arch Dermatol 135(11) 1366 - 1368 1999
Reply to eccrine, apocrine, or sebaceous duct cyst?（共著）

J Cutan Pathol 26(9) 446 - 447 1999
Immunohistochemical observation of cytokeratins in keratinous cysts including plantar epidermoid cyst（共著）

J Cutan Pathol 26(9) 424 - 429 1999
Repeated Ubiquitin Genes in Trichophyton mentagrophytes（共著）

Current Microbiol 39(5) 302 - 305 1999
Chitin synthase 2 gene sequence of Malassezia species

R Kano, T Aizawa, Y Nakamura, S Watanabe, A Hasegawa

MICROBIOLOGY AND IMMUNOLOGY 43(8) 813 - 815 1999
Genital Bowen's disease associated with an unusual human papillomavirus type 57b（共著）

Arch Dermatol 135(7) 858 - 859 1999
Immunohistochemical analysis of cytokeratin expression in various trichogenic tumors（共著）

Am J Dermatopathol 21(4) 337 - 343 1999
Immunohistochemical analysis of cytokeratin expression in apocrine cystadenoma or hidrocystoma（共著）

J Cutan Pathol 26(6) 295 - 300 1999
Does plantar epidermoid cyst with human papillomavirus infection originate from the eccrine dermal duct?（共著）

Br J Dermatol 141(1) 161 - 162 1999
Expression of keratin antigen 20 in perianal Paget's disease（共著）

Br J Dermatol 140(6) 1169 - 1170 1999
Metastasis of gastric carcinoma to a finger（共著）

Br J Dermatol 140(5) 776 - 777 1999
Abnormalities of basal cell keratin in epidermolysis bullosa simplex do not affect the expression patterns of suprabasal keratins and cornified cell envelope proteins. (共著)

Arch Dermatol Res 290(11) 591 - 597 1998
Molecular analysis of chitin synthase 1(CHS1) gene sequences of ┣DBTrichophyton mentagrophytes(/)-┫DB complex and ┣DBT. rubrum(/)-┫DB. (共著)

Curr Microbiol 37(4) 236 - 239 1998
Kasabach-Merritt syndrome associated with angioblastoma. (共著)

Br J Dermatol 139(1) 164 - 166 1998
Differentiation of ┣DBMicrosporum(/)-┫DB species by random amplification of polymorphic DNA(RAPD) and Southern hybridization analyses. (共著)

Mycoses 41(3-4) 229 - 233 1998
Enhanced activity of antifungal drugs by lysozyme against ┣DBCryptococcus neoformans(/)-┫DB. (共著)

Mycoses 41 199 - 202 1998
The first isolation of ┣DBArthroderma benhamiae(/)-┫DB in Japan(共著)

Microbiol Immunol 42(8) 575 - 578 1998
Identification of clinical isolates of ┣DBMicrosporum canis(/)-┫DB and ┣DBM. qypseum(/)-┫DB by random amplification of polymorphic DNA(RAPD) and Southern hybridization analyses(共著)

Mycoses 41(1-2) 139 - 143 1998
Susceptibility testing of ┣DBCryptococcus neoformans(/)-┫DB by urea broth microdilution method. (共著)

Mycoses 41 41 - 44 1998
Isolates of ┣DBCryptococcus neoformans(/)-┫DB serotype A and D developed on canavanine-glycine-bromthymol blue medium. (共著)

Mycoses 41 35 - 40 1998
Papillary eccrine adenoma : Immunohistochemical studies of keratin expression(共著)

J Cutan Pathol 24 564 - 570 1997
Expression of cathepsin D and B in invasion and metastasis of squamous cell carcinoma(共著)

Br J Dermatol 137 361 - 366 1997
Histogenesis of mixed tumor of the skin(apocrine type). Immunohistochemical study of keratin expression(共著)

An J Dermatopathol 19 456 - 461 1997
Keratin and involucrin expression in discoid lupus erythematosus and lichen planus(共著)

Arch Dermatol Res 289(9) 519 - 526 1997
Immunohistochemical analysis of keratin expression in clear cell syringoma. A comparative study with conventional syringoma (共著)

J. Cutan Pathol 24(6) 370 - 376 1997
Histogenesis of clear cell hidradenoma: immunohistochemical study of keratin expression

T. Ohnishi, S. Watanabe

Journal of Cutaneous Pathology 24(1) 30 - 36 1997
Trichoblastic fibroma - A case report and an immunohistochemical study of cytokeratin expression

S Watanabe, H Torii, T Matsuyama, S Harada

AMERICAN JOURNAL OF DERMATOPATHOLOGY 18(3) 308 - 313 Jun, 1996
Sporothrix schenckii isolated from a cat in Japan

Y Nakamura, H Sato, S Watanabe, H Takahashi, K Koide, A Hasegawa

MYCOSES 39(3-4) 125 - 128 Mar, 1996
Erythrodermic psoriasis assoited with hyperuricemia and iatrogenic Cushing's syndrome due to topical corticosteroid therapy (共著)

Int J Dermatol 35(3) 379 - 380 1996
CHANGES IN CYTOKERATIN EXPRESSION IN EPIDERMAL-KERATINOCYTES DURING WOUND-HEALING

S WATANABE, M OSUMI, T OHNISHI, E ICHIKAWA, H TAKAHASHI

HISTOCHEMISTRY AND CELL BIOLOGY 103(6) 425 - 433 Jun, 1995
Eccrine syringofibroadenoma - A case report with immunohistochemical study of Keratin expression (共著)

Br J Dermatol 133(3) 449 - 454 1995
Immunohistochemical characterization of expression in clear cell acanthoma (共著)

Br J Dermatol 133(2) 186 - 193 1995

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