HASHIMOTO Yoshiya

J-GLOBAL         Last updated: Feb 28, 2019 at 14:47
 
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Name
HASHIMOTO Yoshiya
Affiliation
Osaka Dental University
Section
Faculty of Dentistry, Department of Biomaterials
Degree
(BLANK)(Osaka Dental University)

Research Areas

 
 

Education

 
 
 - 
1990
Faculty of Dentistry, Osaka Dental University
 

Published Papers

 
Luyuan Chen, Satoshi Komasa, Yoshiya Hashimoto, Shigeki Hontsu, Joji Okazaki
International Journal of Molecular Sciences   19    Apr 2018
© 2018 by the authors. Licensee MDPI, Basel, Switzerland. To enhance biocompatibility, osteogenesis, and osseointegration, we coated titanium implants, by krypton fluoride (KrF) pulsed laser deposition, with a thin film of fluoridated hydroxyapati...
Kazuya Matsuse, Yoshiya Hashimoto, Sachiro Kakinoki, Tetsuji Yamaoka, Shosuke Morita
Medical Molecular Morphology   51 48-56   Mar 2018
© 2017, The Japanese Society for Clinical Molecular Morphology. We evaluated the effect of porous alpha-tricalcium phosphate (α-TCP) with immobilized basic fibroblast growth factor (bFGF) on periodontal regeneration in a canine model of 2-wall per...
Yoshitomo Honda, Yoshihiro Takeda, Peiqi Li, Anqi Huang, Satoshi Sasayama, Eiki Hara, Naoya Uemura, Mamoru Ueda, Masanori Hashimoto, Kenji Arita, Naoyuki Matsumoto, Yoshiya Hashimoto, Shunsuke Baba, Tomonari Tanaka
Molecules   23    Jan 2018
© 2018 by the authors Chemical modification of gelatin using epigallocatechin gallate (EGCG) promotes bone formation in vivo. However, further improvements are required to increase the mechanical strength and bone-forming ability of fabricated EGC...
Hiroaki Nishikawa, Tsukasa Hasegawa, Akiko Miyake, Akiko Miyake, Yuichiro Tashiro, Satoshi Komasa, Yoshiya Hashimoto
Applied Surface Science   427 458-463   Jan 2018
© 2017 Elsevier B.V. The dependence of the surface morphology and chemical composition of hydroxyapatite (HA) thin films on the laser fluence and ambient gas pressure during their formation by pulsed laser deposition was studied as the first step ...
Yoshiya Hashimoto, Mamoru Ueda, Yu Kohiga, Kazuki Imura, Shigeki Hontsu
Dental Materials Journal   37 408-413   Jan 2018
© 2018, Japanese Society for Dental Materials and Devices. All rights reserved. Fluoridated hydroxyapatite (FHA) was investigated for application as an implant coating for titanium bone substitute materials in dental implants. A KrF pulsed excimer...
Ayato Hieda, Naoya Uemura, Yoshiya Hashimoto, Isumi Toda, Shunsuke Baba
Dental Materials Journal   36 222-229   Jan 2017
© 2017, Japanese Society for Dental Materials and Devices. All rights reserved. The in vivo bioactivity of porous polyetheretherketone (PEEK) with a foamed surface was evaluated using rabbit femoral bone. Cylindrical porous PEEK scaffolds, with po...
Eiko Azumi, Yoshitomo Honda, Naotaka Kishimoto, Yoshiya Hashimoto, Naoyuki Matsumoto
Orthodontic Waves   75 97-104   Dec 2016
© 2016 Elsevier Ltd and The Japanese Orthodontic Society Purpose Human dedifferentiated fat (hDFAT) cells are thought to be a promising cell source for cartilage regeneration therapy. Nevertheless, the responses of hDFAT cells to bone morphogeneti...
Nobuhiro Kobayashi, Yoshiya Hashimoto, Akihisa Otaka, Tetsuji Yamaoka, Shosuke Morita
Materials   9    Oct 2016
© 2016 by the authors. The effect of porous alpha-tricalcium phosphate (α-TCP) with immobilized basic fibroblast growth factor (bFGF) on bone regeneration was evaluated in a canine mandibular bone defect model. Identical bone defects were made in ...
Peiqi Li, Yoshitomo Honda, Yoshiyuki Arima, Kenichirou Yasui, Kaoru Inami, Aki Nishiura, Yoshiya Hashimoto, Naoyuki Matsumoto
Journal of Prosthodontic Research   60 167-176   Jul 2016
© 2016 Japan Prosthodontic Society Purpose Interferon (IFN)-γ is a major cytokine produced by immune cells that plays diverse roles in modulating both the immune system and bone metabolism, but its role in autogenous bone grafting remains unknown....
Wen Liao, Masahiro Okada, Kaoru Inami, Yoshiya Hashimoto, Naoyuki Matsumoto
Cytotechnology   68 249-260   Mar 2016
© 2014, Springer Science+Business Media Dordrecht. This study investigated cell survival and gene expression under various compressive stress conditions mimicking orthodontic force by using a newly developed in vitro model of human periodontal lig...
Hiroaki Nishikawa, Tsukasa Hasegawa, Akiko Miyake, Yuichiro Tashiro, Yoshiya Hashimoto, Dave H.A. Blank, Guus Rijnders
Materials Letters   165 95-98   Feb 2016
© 2015 Elsevier Ltd. All rights reserved. Variation of the Ca/P ratio in hydroxyapatite (Ca10(PO4)6(OH)2) thin films was studied in relation to the spot size of the ablation laser for two different spatial energy distributions in pulsed laser depo...
Peiqi Li, Yoshiya Hashimoto, Yoshitomo Honda, Yuji Nakayama, Nobuhiro Kobayashi, Eiki Hara, Kenichirou Yasui, Yoshiyuki Arima, Naoyuki Matsumoto
Journal of Hard Tissue Biology   25 35-40   Jan 2016
© 2016 The Hard Tissue Biology Network Association Printed in Japan, All rights reserved. In periodontal surgery, autogenous bones are frequently used for bone transplantation. However, the application of autogenous bone is limited by the lack of ...
Akiko Miyake, Satoshi Komasa, Yoshiya Hashimoto, Yutaka Komasa, Joji Okazaki
Advances in Materials Science and Engineering   2016    Jan 2016
© 2016 Akiko Miyake et al. The aim of this study was to evaluate the difference in the adsorption behavior of different types of bovine salivary proteins on the PMMA and Ti QCM sensors are fabricated by spin-coating and sputtering onto bare QCM se...
Koji Kaida, Yoshitomo Honda, Yoshiya Hashimoto, Masahiro Tanaka, Shunsuke Baba
International Journal of Molecular Sciences   16 27988-28000   Nov 2015
© 2015 by the authors; licensee MDPI, Basel, Switzerland. Despite advances in stem cell biology, there are few effective techniques to promote the osteogenic differentiation of human primary dedifferentiated fat (DFAT) cells. We attempted to inves...
Peiqi Li, Yoshiya Hashimoto, Yoshitomo Honda, Yoshiyuki Arima, Naoyuki Matsumoto
International Journal of Molecular Sciences   16 25678-25690   Oct 2015
© 2015 by the authors; licensee MDPI, Basel, Switzerland. Inflammatory responses are frequently associated with the expression of inflammatory cytokines and severe osteoclastogenesis, which significantly affect the efficacy of biomaterials. Recent...
Yoshitomo Honda, Tomonari Tanaka, Tomoko Tokuda, Takahiro Kashiwagi, Koji Kaida, Ayato Hieda, Yasuyuki Umezaki, Yoshiya Hashimoto, Koichi Imai, Naoyuki Matsumoto, Shunsuke Baba, Kimishige Shimizutani, Kimishige Shimizutani
International Journal of Molecular Sciences   16 14143-14157   Jun 2015
© 2015 by the authors; licensee MDPI, Basel, Switzerland. Catechins are extensively used in health care treatments. Nevertheless, there is scarce information about the feasibility of local administration with polyphenols for bone regeneration ther...
Yasuyuki Umezaki, Yoshiya Hashimoto, Naoki Nishishita, Shin Kawamata, Shunsuke Baba
International Journal of Molecular Sciences   16 13633-13648   Jun 2015
© 2015 by the authors; licensee MDPI, Basel, Switzerland. Mesenchymal stem cells (MSCs) are considered a potential autologous therapy for tissue engineering. The available procedures for MSC retrieval from patients are invasive, and their limited ...
Naoya Okita, Yoshitomo Honda, Naotaka Kishimoto, Wen Liao, Eiko Azumi, Yoshiya Hashimoto, Naoyuki Matsumoto
Tissue Engineering - Part A   21 1695-1704   May 2015
© 2015, Mary Ann Liebert, Inc. 2015. Dedifferentiated fat cells (DFAT cells) isolated from adipose tissue have been demonstrated to differentiate into chondrogenic cells in vitro. Nevertheless, an efficient method to facilitate its chondrogenic di...
Yoshiya Hashimoto, Hiroaki Nishikawa, Masanobu Kusunoki, Peiqi Li, Shigeki Hontsu
Dental Materials Journal   34 345-350   Apr 2015
© 2015, Japanese Society for Dental Materials and Devices. All rights reserved. Cell sheet technology is a scaffold-free method for tissue reconstruction. A sheet-shaped scaffold would be suitable for the regeneration of periodontal membrane. We d...
Tomohiko Ito, Yoshiya Hashimoto, Shunsuke Baba, Tomio Iseki, Shosuke Morita
Implant Dentistry   24 197-203   Jan 2015
Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved. Introduction: We evaluated the effects of synthesized collagen model polypeptides consisting of a proline-hydroxyproline-glycine (poly(PHG)) sequence combined with porous alpha-tric...
Hiroki Nakamura, Tomonori Matsuno, Yoshiya Hashimoto, Tatsuo Nakamura, Izumi Mataga
Journal of Hard Tissue Biology   24 347-356   Jan 2015
© 2015 The Hard Tissue Biology Network Association Printed in Japan, All rights reserved. This study aimed to compare the response of peri-implant tissue surrounding hydroxyapatite-coated titanium (HA) implants and anodic oxidized titanium (AnO) i...
Tomoko Tokuda, Yoshitomo Honda, Yoshiya Hashimoto, Naoyuki Matsumoto
Nano Biomedicine   7 63-71   Jan 2015
Alpha-Tricalcium phosphate (α-TCP) has been investigated extensively as an artificial bone graft; however, the relationship between size of α-TCP particles and its bone-formation capability is not clear. In the present study, we compared the bone-...
Kazuhiko Omata, Tomonori Matsuno, Kazunari Asano, Kazunari Asano, Yoshiya Hashimoto, Yasuhiko Tabata, Tazuko Satoh
Journal of Tissue Engineering and Regenerative Medicine   8 604-611   Jan 2014
The objective of this study was to investigate the feasibility of biodegradable gelatin-β-tricalcium phosphate (β-TCP) composites as a cell scaffold and controlled-release carrier of basic fibroblast growth factor (bFGF) suitable for inducing bone...
Wen Liao, Masahiro Okada, Fumito Sakamoto, Naoya Okita, Kaoru Inami, Aki Nishiura, Yoshiya Hashimoto, Naoyuki Matsumoto
Materials Science and Engineering C   33 3273-3280   Aug 2013
This study aimed to establish an in vitro human periodontal ligament-like tissue (HPdLLT) by three-dimensional culturing of human periodontal ligament fibroblasts (HPdLFs) in a porous poly-l-lactide (PLLA) matrix modified hydrophilically with ammo...
Yusuke Hashimoto, Yoshiya Hashimoto, Aki Nishiura, Naoyuki Matsumoto
Dental Materials Journal   32 181-188   Apr 2013
Orthodontists use a self-etching adhesive system when attaching brackets to enamel. The purpose of this study was to evaluate the erosion effects of common clinically used adhesive systems on human enamel surfaces by atomic force microscopy (AFM)....
Yuya Yoneyama, Tomonori Matsuno, Yoshiya Hashimoto, Tazuko Satoh
Dental Materials Journal   32 115-121   Apr 2013
Surface modification of titanium has been extensively investigated in implant science and technology in an effort to improve its osteoconductivity. The rate of protein adsorption on titanium surfaces is known to vary depending on the chemistry, st...
Yoshiyuki Arima, Naoya Uemura, Yoshiya Hashimoto, Shunsuke Baba, Naoyuki Matsumoto
Orthodontic Waves   72 23-29   Mar 2013
Purpose: Both atelocollagen and alpha-tricalcium phosphate (α-TCP) particles are widely applied as bone graft materials. In this study, we combined atelocollagen and porous α-TCP particles to form an α-TCP/atelocollagen composite sponge (α-TCP/CS)...
Naotaka Kishimoto, Naotaka Kishimoto, Yoshihiro Momota, Yoshihiro Momota, Yoshiya Hashimoto, Kayoko Ando, Takeshi Omasa, Junichiro Kotani
Cytotechnology   65 15-22   Jan 2013
Mature adipocyte-derived dedifferentiated fat (DFAT) cells rapidly differentiate into osteoblasts under three-dimensional culture conditions. However, it has not been demonstrated that DFAT cells can differentiate into osteoblasts in a rigid scaff...
Fumito Sakamoto, Yoshiya Hashimoto, Naotaka Kishimoto, Yoshitomo Honda, Naoyuki Matsumoto
Cytotechnology   67 75-84   Jan 2013
© 2013, Springer Science+Business Media Dordrecht. We compared the osteoblastic differentiation abilities of dedifferentiated fat cells (DFATs) and human bone marrow mesenchymal stem cells (hMSCs) as a cell source for bone regeneration therapies. ...
Naotaka Kishimoto, Naotaka Kishimoto, Yoshihiro Momota, Yoshihiro Momota, Yoshiya Hashimoto, Shinichi Tatsumi, Kayoko Ando, Takeshi Omasa, Junichiro Kotani
Clinical Oral Investigations   18 1893-1901   Jan 2013
© 2013, The Author(s). Objectives: The purpose of this study was to evaluate and compare the osteoblastic differentiation ability of dedifferentiated fat (DFAT) cells and adipose stem cells (ASCs) from the buccal fat pad (BFP).Materials and method...
Hidenori Shimada, Yoshiya Hashimoto, Akira Nakada, Keiji Shigeno, Tatsuo Nakamura
Biochemical and Biophysical Research Communications   417 659-664   Jan 2012
Induced pluripotent stem (iPS) cells are generated from somatic cells by the forced expression of a defined set of pluripotency-associated transcription factors. Human iPS cells can be propagated indefinitely, while maintaining the capacity to dif...
Kenichirou Yasui, Yoshiya Hashimoto, Shunsuke Baba, Shigeki Hontsu, Naoyuki Matsumoto
Nano Biomedicine   4 133-142   Jan 2012
This study examined in vivo biocompatability of poly-L-lactide (PLLA) scaffolds coated with hydroxyl apatite (HA) by pulsed laser deposition (PLD). A thin HA film was made on PLLA discs by an ArF PLD operating at a repletion rate of 10 Hz. Cranial...
Kana Sakai, Yoshiya Hashimoto, Shunsuke Baba, Aki Nishiura, Naoyuki Matsumoto
Dental Materials Journal   30 913-922   Dec 2011
We evaluated the effects on bone formation of combining synthesized collagen model polypeptides consisting of a Pro-Hyp-Gly [poly(PHG)] sequence and alpha-tricalcium phosphate (a-TCP) particles with various median sizes (large: 580.8 μm; small: 13...
Shunsuke Baba, Takeomi Inoue, Yoshiya Hashimoto, Daisuke Kimura, Masatoshi Ueda, Kana Sakai, Naoyuki Matsumoto, Chiaki Hiwa, Taiji Adachi, Masaki Hojo
Dental Materials Journal   29 673-681   Dec 2010
To date, there has been no study on the development of novel regimens based on the following tissue engineering principles: seeding and culturing mesenchymal stem cells (MSCs) on a scaffold before surgery or injecting cultured MSCs into a scaffold...
Kazuhiko Omata, Tomonori Matsuno, Yoshiya Hashimoto, Kazunari Asano, Yasuhiko Tabata, Tazuko Satoh
Journal of the Australian Ceramic Society   46 6-9   Dec 2010
The objective of this study was to investigate the feasibility of biodegradable gelatin/β-tricalcium phosphate (β-TCP) composites as a cell scaffold and controlled-release carrier of basic fibroblast growth factor (bFGF) suitable to induce bone re...
Sae Minoura, Yoshiya Hashimoto, Aki Nishiura, Ryo Honda, Naoyuki Matsumoto
Nano Biomedicine   2 114-122   Dec 2010
We fabricated quartz crystal microbalance sensors coated with titanium, stainless steel (SS), alumina (Al2O3), and yttria tetragonal zirconia polycrystal (Y-TZP), which were prepared by DC magnetron sputtering. The crystal resonance frequency shif...
Tomonori Matsuno, Kazuhiko Omata, Yoshiya Hashimoto, Yasuhiko Tabata, Yasuhiko Tabata, Tazuko Satoh
Japanese Dental Science Review   46 188-192   Aug 2010
For many years, bone graft substitutes have been used to reconstruct bone defects in orthopedic and dental fields. However, synthetic bone substitutes such as hydroxyapatite or β-tricalcium phosphate have no osteoinductive or osteogenic abilities....
Hidenori Shimada, Akira Nakada, Yoshiya Hashimoto, Keiji Shigeno, Yoshiki Shionoya, Tatsuo Nakamura
Molecular Reproduction and Development   77 2   Jan 2010
Yoshiya Hashimoto, Seita Adachi, Tomonori Matsuno, Kazuhiko Omata, Yamauchi Yoshitaka, Yasuyuki Ozeki, Yoshikazu Umezu, Tazuko Satoh, Masaaki Nakamura
Bio-Medical Materials and Engineering   19 391-400   Dec 2009
The objective of this study was to evaluate the effect of β-tricalcium phosphate (β-TCP) bead size on the behavior of KUSA/A1 mouse osteoblasts when the β-TCP beads are used as the solid phase of a scaffold in which alginate was used as the gel ph...
Masanobu Kusunoki, Yoshitaka Togo, Takuto Wada, Yoshiya Hashimoto, Yoshiya Hashimoto, Hiroaki Nishikawa, Shigeki Hontsu
IEEJ Transactions on Electronics, Information and Systems   129    Jan 2009
We developed a patterning technique for nerve cells that uses polytetrafluoroethylene (PTFE) and poly-D-lysine (PDL). The PDL layer on the PTFE substrate acted as a buffer for nerve cell adhesion, while Ar ion-irradiated areas on PTFE were used fo...
Tomonori Matsuno, Yoshiya Hashimoto, Seita Adachi, Kazuhiko Omata, Kazuhiko Omata, Yamauchi Yoshitaka, Yasuyuki Ozeki, Yoshikazu Umezu, Yasuhiko Tabata, Masaaki Nakamura, Tazuko Satoh
Dental Materials Journal   27 827-834   Dec 2008
A novel, injectable bone tissue engineering material was developed that consisted of β-tricalcium phosphate (β-TCP) beads as the solid phase and alginate as the gel phase. To prepare the instantaneously formed composite scaffold, an aqueous calciu...
Y. Hashimoto, M. Kawashima, R. Hatanaka, M. Kusunoki, H. Nishikawa, S. Hontsu, M. Nakamura
Journal of Materials Science: Materials in Medicine   19 327-333   Jan 2008
In the current studies, we deposited ultra-thin hydroxyapatite films on a pure titanium substrate by pulsed laser deposition, and we examined the effects of these surfaces on rat bone marrow (RBM) cells. This method allowed deposition of 500-, 2,0...
Y. Hashimoto, M. Kawashima, R. Hatanaka, M. Kusunoki, H. Nishikawa, S. Hontsu, M. Nakamura
Journal of Materials Science: Materials in Medicine   18 1457-1464   Jul 2007
In the current studies, we deposited ultra-thin hydroxyapatite films on a pure titanium substrate by pulsed laser deposition, and we examined the effects of these surfaces on rat bone marrow (RBM) cells. This method allowed deposition of 500-, 200...
Haruka Imai, Masanobu Kusunoki, Masanobu Kusunoki, Masanobu Kusunoki, Yoshiya Hashimoto, Yoshiya Hashimoto, Hiroaki Nishikawa, Hiroaki Nishikawa, Hiroaki Nishikawa, Shigeki Hontsu, Shigeki Hontsu, Shigeki Hontsu
IEEJ Transactions on Electronics, Information and Systems   127    Jan 2007
Biological molecular adsorption on crystal hydroxyapatite (HAp) and amorphous Ca10(PO4)6(OH)2was investigated using quartz crystal microbalance (QCM) method. The pulsed laser ablation (PLA) was applied to coat both kind films for QCM sensors. A cr...
Yoshiya Hashimoto, Jiro Tanaka, Kazuomi Suzuki, Masaaki Nakamura
Dental Materials Journal   26 785-791   Jan 2007
In the current study, we examined the cytocompatibility of eight vinyl esters as candidate plasticizers for producing phthalate- and ethanol-free tissue conditioners. We measured the estrogenic activity and cytotoxicity of vinyl esters in human fi...
Tomonori Matsuno, Tomonori Matsuno, Tatsuo Nakamura, Koh Ichi Kuremoto, Syunsuke Notazawa, Taka Nakahara, Yoshiya Hashimoto, Tazuko Satoh, Yasuhiko Shimizu
Dental Materials Journal   25 138-144   Mar 2006
Synthetic biomaterials have been developed and used for bone grafting. Here, we developed a biodegradable sponge composite for bone tissue engineering by combining β-tricalcium phosphate (β-TCP) and collagen. In addition, we sought to determine th...
Yoshiya Hashimoto, Akihiro Ueda, Masaaki Nakamura
Dental Materials Journal   23 184-189   Jan 2004
In the current studies, we examined the possibility of using HSP70 gene regulation as a cytocompatibility test for dental biomaterials. For this reason, we assessed the effects of three metal salts, HgCl2, CuSO4and NiCl2on HSP70 gene expression in...
Yoshiya Hashimoto, Masaaki Nakamura
Dental Materials Journal   23 412-418   Jan 2004
We prepared prototype phthalate ester-free tissue conditioners (PFT) from a powder of poly (ethyl methacrylate) and a mixture of several liquids, including di-n-butyl sebacate, benzyl benzoate (BB), and ethanol. The estrogenic activities of the li...
Yoshiya Hashimoto, Minoru Kawaguchi, Koji Miyazaki, Masaaki Nakamura
Dental Materials   19 341-346   Jun 2003
Objectives. In order to assess the estrogenic activities of plasticizers used in tissue conditioners and four commercial tissue conditioners, we carried out in vitro tests. Methods. Seven plasticizers and two metabolites were diluted to concentrat...

Misc

 
Ei Yamamoto, Nobuhiro Kato, Arata Isai, Hiroaki Nishikawa, Yoshiya Hashimoto, Kazushi Yoshikawa, Shigeki Hontsu
Key Engineering Materials   631 262-266   Jan 2015
© (2015) Trans Tech Publications, Switzerland. It has been well known that bone has piezoelectric properties and these properties have been considered to be caused by the shift of the center of symmetry of the positive and negative electrical char...

Books etc

 
Cell-to-Materials Interaction-An Approach to Elucidate Biocompatibility of Biomaterials In Vitro(共著)
Biomaterials' Mechanical Properties. ASTM STP1173, Philadelphia   1994   

Research Grants & Projects

 
In vitro cytotoxicity test under dynamic extraction
Biological Evaluation of New Glass Ionomer Cements
The study of endocrine disruptor on dental materials.
The effect of laser annealing on HA implant