MIZUGUCHI Hiroyuki

J-GLOBAL         Last updated: Aug 20, 2019 at 14:06
 
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Name
MIZUGUCHI Hiroyuki
Affiliation
Osaka Ohtani University
Section
Faculty of Phamacy
Job title
Associate Professor
Degree
Doctor of Philosophy(Osaka University), Master of Medical Science(Osaka University), Bachelor of Science(Osaka City University)

Research Areas

 
 

Academic & Professional Experience

 
 
 - 
Mar 2006
19924-2006.3 Research Associate, Osaka Medical College.
 
Apr 2006
   
 
- Associate Professor, Tokushima University
 

Education

 
 
 - 
1992
Graduate School, Division of Medicine, Osaka University
 
 
 - 
1986
Faculty of Science, Osaka City University
 

Published Papers

 
Effects of irradiation with narrowband-ultraviolet B on up-regulation of histamine H1 receptor mRNA and induction of apoptosis in HeLa cells and nasal mucosa of rats.
Fujii T, Kitamura Y, Mizuguchi H, Okamoto K, Sanada N, Yamada T, Sugiyama M, Michinaga S, Kitayama M, Fukui H, Takeda N.
J Pharmacol Sci.   138 54-62   2018   [Refereed]
Effect of wild grape on the signaling of histamine H1 receptor gene expression responsible for the pathogenesis of allergic rhinitis.
Islam R, Mizuguchi H, Shaha A, Nishida K, Yabumoto M, Ikeda H, Fujino H, Kitamura Y, Fukui H, Takeda N.
J Med Invest.   65 242-250   2018   [Refereed]
Effect of royal jelly and Brazilian green propolis on the signaling for histamine H1 receptor and interleukin-9gene expressions responsible for the pathogenesis of the allergic rhinitis.
Shaha A, Mizuguchi H, Kitamura Y, Fujino H, Yabumoto M, Takeda N, Fukui H.
Biol Pharm Bull.   41 1440-1447   2018   [Refereed]
Protein kinase C-δ signaling regulates glucagon secretion from pancreatic islets.
Yamamoto K, Mizuguchi H, Tokashiki N, Kobayashi M, Tamaki M, Sato Y, Fukui H, Yamauchi A.
J Med Invest.   64 122-128   2017   [Refereed]
Fukui H, Mizuguchi H, Nemoto H, Kitamura Y, Kashiwada Y, Takeda N
Handbook of experimental pharmacology      Nov 2016   [Refereed]
Sekita Y, Murakami K, Yumoto H, Mizuguchi H, Amoh T, Ogino S, Matsuo T, Miyake Y, Fukui H, Kashiwada Y
Bioscience, biotechnology, and biochemistry   80(6) 1205-1213   Jun 2016   [Refereed]
Mizuguchi H, Das AK, Maeyama K, Dev S, Shahriar M, Kitamura Y, Takeda N, Fukui H
Journal of pharmacological sciences   130(4) 212-218   Apr 2016   [Refereed]
Mizuguchi H, Orimoto N, Kadota T, Kominami T, Das AK, Sawada A, Tamada M, Miyagi K, Adachi T, Matsumoto M, Kosaka T, Kitamura Y, Takeda N, Fukui H
Journal of pharmacological sciences   130(3) 151-158   Mar 2016   [Refereed]
Fukui H, Mizuguchi H, Kashiwada Y, Nemoto H, Kitamura Y, Takeda N
Nihon yakurigaku zasshi. Folia pharmacologica Japonica   147(3) 148-151   Mar 2016   [Refereed]
Shill MC, Mizuguchi H, Karmakar S, Kadota T, Mukherjee PK, Kitamura Y, Kashiwada Y, Nemoto H, Takeda N, Fukui H
International immunopharmacology   30 18-26   Jan 2016   [Refereed]
Kitamura Y, Mizuguchi H, Okamoto K, Kitayama M, Fujii T, Fujioka A, Matsushita T, Mukai T, Kubo Y, Kubo N, Fukui H, Takeda N
Acta oto-laryngologica   136(4) 409-413   2016   [Refereed]
Nariai Y, Mizuguchi H, Ogasawara T, Nagai H, Sasaki Y, Okamoto Y, Yoshimura Y, Kitamura Y, Nemoto H, Takeda N, Fukui H
The Journal of biological chemistry   290(45) 27393-27402   Nov 2015   [Refereed]
Kitamura Y, Nakagawa H, Fujii T, Sakoda T, Enomoto T, Mizuguchi H, Fukui H, Takeda N
Journal of pharmacological sciences   129(3) 183-187   Nov 2015   [Refereed]
Shill MC, Das AK, Itou T, Karmakar S, Mukherjee PK, Mizuguchi H, Kashiwada Y, Fukui H, Nemoto H
Bioorganic & medicinal chemistry   23(21) 6869-6874   Nov 2015   [Refereed]
Mizuguchi H, Nariai Y, Kato S, Nakano T, Kanayama T, Kashiwada Y, Nemoto H, Kawazoe K, Takaishi Y, Kitamura Y, Takeda N, Fukui H
Pharmacology research & perspectives   3(5) e00166   Oct 2015   [Refereed]
Mizuguchi H, Ono S, Hattori M, Sasaki Y, Fukui H
International immunopharmacology   15(3) 539-543   Mar 2013   [Refereed]
Hattori M, Mizuguchi H, Baba Y, Ono S, Nakano T, Zhang Q, Sasaki Y, Kobayashi M, Kitamura Y, Takeda N, Fukui H
International immunopharmacology   15(2) 232-239   Feb 2013   [Refereed]
Kuroda W, Kitamura Y, Mizuguchi H, Miyamoto Y, Kalubi B, Fukui H, Takeda N
Journal of pharmacological sciences   122(1) 55-58   2013   [Refereed]
Umehara H, Mizuguchi H, Fukui H
Neurochemistry international   61(6) 942-947   Nov 2012   [Refereed]
Kitamura Y, Mizuguchi H, Ogishi H, Kuroda W, Hattori M, Fukui H, Takeda N
Acta oto-laryngologica   132(4) 434-438   Apr 2012   [Refereed]
Sarkar L, Bhuvaneswari N, Samanta SK, Islam MN, Sen T, Fukui H, Mizuguchi H, Karmakar S
Journal of ethnopharmacology   140(2) 443-446   Mar 2012   [Refereed]
Mizuguchi H, Ono S, Hattori M, Fukui H
Journal of pharmacological sciences   118(1) 117-121   2012   [Refereed]
Mizuguchi H, Miyagi K, Terao T, Sakamoto N, Yamawaki Y, Adachi T, Ono S, Sasaki Y, Yoshimura Y, Kitamura Y, Takeda N, Fukui H
Scientific reports   2 916   2012   [Refereed]
Nurul IM, Mizuguchi H, Shahriar M, Venkatesh P, Maeyama K, Mukherjee PK, Hattori M, Choudhuri MS, Takeda N, Fukui H
International immunopharmacology   11(11) 1766-1772   Nov 2011   [Refereed]
Dev S, Mizuguchi H, Das AK, Baba Y, Fukui H
International immunopharmacology   11(10) 1504-1509   Oct 2011   [Refereed]
Mizuguchi H, Terao T, Kitai M, Ikeda M, Yoshimura Y, Das AK, Kitamura Y, Takeda N, Fukui H
The Journal of biological chemistry   286(35) 30542-30551   Sep 2011   [Refereed]
Mizuguchi H, Kitamura Y, Kondo Y, Kuroda W, Yoshida H, Miyamoto Y, Hattori M, Takeda N, Fukui H
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan   131(2) 171-178   Feb 2011   [Refereed]
Umehara H, Mizuguchi H, Mizukawa N, Matsumoto M, Takeda N, Senba E, Fukui H
Methods and findings in experimental and clinical pharmacology   32(10) 733-736   Dec 2010   [Refereed]
Mizuguchi H, Kitamura Y, Kondo Y, Kuroda W, Yoshida H, Miyamoto Y, Hattori M, Fukui H, Takeda N
Methods and findings in experimental and clinical pharmacology   32(10) 745-748   Dec 2010   [Refereed]
Venkatesh P, Mukherjee PK, Mukherjee D, Bandyopadhyay A, Fukui H, Mizuguchi H
Pharmaceutical biology   48(11) 1213-1217   Nov 2010   [Refereed]
Venkatesh P, Mukherjee PK, Kumar NS, Nema NK, Bandyopadhyay A, Fukui H, Mizuguchi H
J Ethnopharmacol.   126 434-436   2009   [Refereed]
Shahriar M, Mizuguchi H, Maeyama K, Kitamura Y, Orimoto N, Horio S, Umehara H, Hattori M, Takeda N, Fukui H.
J Immunol.   183(3) 2133-2141   2009   [Refereed]
Dev S, Mizuguchi H, Das AK, Maeyama K, Horinaga S, Kato S, Tamada M, Hattori M, Umehara H, Fukui H.
J Pharmacol Sci.   109(4) 606-617   2009   [Refereed]
Das AK, Mizuguchi H, Kodama M, Dev S, Umehara H, Kitamura Y, Matsushita C, Takeda N, Fukui H. (*AKD and HM contributed equally to this work.)
Allergol Int.   58(1) 81-88   2009   [Refereed]
Mizuguchi H, Hatano M, Matsushita C, Umehara H, Kuroda W, Kitamura Y, Takeda N, Fukui H
Journal of pharmacological sciences   108(4) 480-486   Dec 2008   [Refereed]
Matsushita C, Mizuguchi H, Niino H, Sagesaka Y, Masuyama K, Fukui H.
J Trad Med.   25(5/6) 133-142   2008   [Refereed]
Sakiyama H, Wynn RM, Lee WR, Fukasawa M, Mizuguchi H, Gardner KH, Repa JJ, Uyeda K.
J Biol Chem.   283(36) 24899-24908   2008   [Refereed]
Izumi N, Mizuguchi H, Umehara H, Ogino S, Fukui H.
Allergol Int.   57(3) 257-263   2008   [Refereed]
Izumi N, Mizuguchi H, Umehara H, Ogino S, Fukui H.
Methods Find Exp Clin Pharmacol.   30(3) 225-230   2008   [Refereed]
Dev S, Mizuguchi H, Das AK, Matsushita C, Maeyama K, Umehara H, Ohtoshi T, Kojima J, Nishida K, Takahashi K, Fukui H.
J Pharmacol Sci.   107(2) 159-166   2008   [Refereed]
Das AK, Yoshimura S, Mishima R, Fujimoto K, Mizuguchi H, Dev S, Wakayama Y, Kitamura Y, Horio S, Takeda N, Fukui H.
J Pharmacol Sci.   103(4) 374-382   2007   [Refereed]
Goto M, Omi R, Miyahara I, Hosono A, Mizuguchi H, Hayashi H, Kagamiyama H, Hirotsu K
The Journal of biological chemistry   279(16) 16518-16525   Apr 2004   [Refereed]
Omi R, Goto M, Miyahara I, Mizuguchi H, Hayashi H, Kagamiyama H, Hirotsu K
The Journal of biological chemistry   278(46) 46035-46045   Nov 2003   [Refereed]
Matsunaga M, Ohtaki H, Takaki A, Iwai Y, Yin L, Mizuguchi H, Miyake T, Usumi K, Shioda S
Neuroscience research   47(3) 269-276   Nov 2003   [Refereed]
Hosono A, Mizuguchi H, Hayashi H, Goto M, Miyahara I, Hirotsu K, Kagamiyama H
J. Biochem.   134 843-851   2003   [Refereed]
Mizuguchi H, Hayashi H, Miyahara I, Hirotsu K, Kagamiyama H
Biochim. Biophys. Acta   1647 321-324   2003   [Refereed]
Hayashi H, Mizuguchi H, Miyahara I, Islam MM, Ikushiro H, Nakajima Y, Hirotsu K, Kagamiyama H
Biochem. Biophys. Acta   1647 103-109   2003   [Refereed]
HAYASHI H, MIZUGUCHI H, MIYAHARA I, NAKAJIMA Y, HIROTSU K, KAGAMIYAMA H
J. Biol. Chem.   278(11) 9481-9488   2003   [Refereed]
Structure of Imidazole Glycerol Phosphate Synthase from Thermus thermophilus HBS:Open-Closed conformational Change and Ammonia Tunneling
Omi R, Mizuguchi H, Goto M, Miyahara I, Hayashi H, Kagamiyama H, Hirotsu K
132 759-765   2002   [Refereed]
HARUYAMA K, NAKAI T, MIYAHARA I, HIROTSU K, MIZUGUCHI H, HAYASHI H, KAGAMIYAMA H
Biochemistry   40(15) 4633-4644   2001   [Refereed]
MIZUGUCHI H, HAYASHI H, OKADA K, MIYAHARA I, HIROTSU K, KAGAMIYAMA H
Biochemistry   40(2) 353-360   2001   [Refereed]
ISLAM M M, HAYASHI H, MIZUGUCHI H, KAGAMIYAMA H
Biochemistry   39(50) 15418-15428   2000   [Refereed]
YUEN M H, WANG X‐L, MIZUGUCHI H, UYEDA K, HASEMANN C A
Biochemistry   38 12333-12342   1999   [Refereed]
MIZUGUCHI H, COOK P F, TAI C‐H, HASEMANN C A, UYEDA K
J. Biol. Chem.   274(4) 2166-2175   1999   [Refereed]
HELMS M K, HAZLETT T L, MIZUGUCHI H, HASEMANN C A, UYEDA K, JAMESON D M
Biochemistry   37(40) 14057-14064   1998   [Refereed]
UYEDA K, WANG X‐L, MIZUGUCHI H, LI Y, NGUYEN C, HASEMANN C A
J Biol Chem   272(12) 7867-7872   1997   [Refereed]
Functionally important residues of aromatic L-amino acid decarboxylase probed by sequence alignment and site-directed mutagenesis.
Ishii S, Mizuguchi H, Nishino J, Hayashi H, Kagamiyama H
J Biochem   120 369-376   1996   [Refereed]
Purification and characterization of [3H]mepyramine (histamine H1 antagonist)-binding protein from rat liver: a highly homologous protein with cytochrome P450 2D.
Fukui H, Mizuguchi H, Liu YQ, Wang NP, Hayashi H, Kangawa K, Wakamiya T, Leurs R, Shiba T, Matsuo H
Journal of biochemistry   117(5) 993-998   May 1995   [Refereed]
Purification and characterization of [3H]mepyramine(histamine H1 antagonist)-binding protein from rat liver : a highly homologous protein with cytochrome P450 2D.
Fukui H, Mizuguchi H, Liu YQ, Wang NP, Hayashi H, Kangawa K, Wakamiya T, Leurs R, Shiba T, Matsuo H.
J Biochem   117 993-998   1995   [Refereed]
Expression and characterization of the bovine histamine H1 receptor in cDNA-transfected C6 astroglioma cells.
Mizuguchi H, Ito S, Shevchenko VI, Nagasawa Y, Yamashita M, Imamura I, Horio Y, Fujimoto K, Fukui H
Journal of biochemistry   115(6) 1155-1161   Jun 1994   [Refereed]
OHTA K, HAYASHI H, MIZUGUCHI H, KAGAMIYAMA H, FUJIMOTO K, FUKUI H
Biochem Biophys Res Commun   203(2) 1096-1101   1994   [Refereed]
Purification and characterization of diamine oxidase(histaminase)from rat small intestine.
Mizuguchi H, Imamura I, Takemura M, Fukui H
J Biochem   116 631-635   1994   [Refereed]
TAKEMURA M, IMAMURA I, MIZUGUCHI H, FUKUI H, YAMATODANI A
Life Sci   54(15) 1059-1071   1994   [Refereed]
Expression and characterization of the bovine histamine H1 receptor in cDNA-transfected C6 astroglioma cells.
Mizuguchi H, Ito S, Shevchenko VI, Nagasawa Y, Yamashita M, Imamura I, Horio Y, Fujimoto K, Fukui H
J Biochem   115 1155-1161   1994   [Refereed]
FUKUI H, FUJIMOTO K, MIZUGUCHI H, SAKAMOTO K, HORIO Y, TAKAI S, YAMADA K, ITO S
Biochem biophys Res Commun   201(2) 894-901   1994   [Refereed]
Hayashi H, Mizuguchi H, Kagamiyama H
Biochemistry   32 812-818   1993   [Refereed]
Liu YQ, Horio Y, Mizuguchi H, Fujimoto K, Imamura I, Abe Y, Fukui H
Biochemical and biophysical research communications   189(1) 378-384   Nov 1992   [Refereed]
Histamine N-Methyltransferase from Rat Kidney CLONING, NUCLEOTIDE SEQUENCE, AND EXPRESSION IN ESCHERICHIA COLI CELLS
Takemura M, Tanaka T, Taguchi Y, Imamura I, Mizuguchi H, Kuroda M, Fukui H, Yamatodani A, Wada H
The Journal of Biological Chemistry   267 15687-15691   1992   [Refereed]
Yamashita M, Fukui H, Sugama K, Horio Y, Ito S, Mizuguchi H, Wada H
Proceedings of the National Academy of Sciences of the United States of America   88(24) 11515-11519   Dec 1991   [Refereed]
Fujimoto K, Mizuguchi H, Fukui H, Wada H
Biochemical and biophysical research communications   177(3) 907-912   Jun 1991   [Refereed]
Mizuguchi H, Fukui H, Yabumoto M, Wada H
Biochemical and biophysical research communications   174(2) 1043-1047   Jan 1991   [Refereed]
Adenosine Induces System A Amino Acid Transport in Cultured Rat Hepatocytes
Kiyokawa H, Fukui H, Mizuguchi H, Kubo A, Kono N, Tarui S, Wada H
The Journal of Biochemistry   110 9-11   1991   [Refereed]
Mizuguchi H, Yabumoto M, Imamura I, Fukui H, Wada H
Biochemical and Biophysical Research Communications   173 1299-1303   1990   [Refereed]

Misc

 
Purification of [3H] Mepyramine Receptor from Rat Liver and its Amino Acid Sequence Homology with Debrisoquine 4-Hydroxylase Cytochrome P-450
European Journal of Pharmacology   183    1990
Structure of Imidazole Glycerol Phosphate Synthase from Thermus thermophilus HB8:Open-Closed conformational Change and Ammonia Tunneling
J.Biochem.   132(5),759-765    2002

Books etc

 
Enzymes Dependent on Pyridoxal phosphate and other carbonyl compounds as cofactors
pergamon press   1990   

Research Grants & Projects

 
Regulatory Mechanism of Histamine H1 receptor gene expression and search for new drugs that target for allergic diseases-related gene expression
Grant-in-Aid for Scientific Research