J-GLOBAL         Last updated: Mar 26, 2019 at 09:59
Osaka University of Pharmaceutical Sciences
Graduate School of Pharmaceutical Sciences, Department of Physiological Chemistry
Job title
(BLANK)(Osaka University of Pharmaceutical Sciences)

Research Areas



Hygienic Chemistry, Graduate School, Division of Pharmaceutical Sciences, Osaka University of Pharmaceutical Sciences
Faculty of Pharmaceutical Science, Osaka University of Pharmaceutical Sciences

Published Papers

Taxifolin potently diminishes levels of reactive oxygen species in living cells possibly by scavenging peroxyl radicals.
Sakuma S, Kishiwaki Y, Matsumura M, Sawada H, Hashimoto R, Gotoh K, Umemoto K, Fujimoto Y.
Am. J. Pharmacol. Toxicol.   13 1-6   Oct 2018   [Refereed]
The peptide glycyl-L-histidyl-L-lysine is an endogenous antioxidant in living oranisms, possibly by diminishing hydroxyl and peroxyl radicals.
Sakuma S, Ishimura M, Yuba Y, Itoh Y, Fujimoto Y.
Int. J. Physiol. Pathophysiol. Pharmacol.   10(3) 132-138   Jun 2018   [Refereed]
Curcumin inhibits adipogenesis elicited by clozapine in 3T3-L1 cells.
Sakuma S, Sumida M, Sakabe A, Nakamura A, Noda C, Kohda T, Tsujimoto K, Kobayashi M, Sano T, FujimotoY.
Food Nutr. Sci.   9(5) 584-594   May 2018   [Refereed]
Curcumin inhibits adipogenesis induced by benzyl butyl phthalate in 3T3-L1 cells.
SAKUMA SatoruSakuma S, Sumida M, Endoh Y, Yamaguchi A, Watanabe T, Kohda T, Tsukiyama Y, Fujimoto Y.
Toxicol. Appl. Pharmacol.   329 158-164   2017   [Refereed]
Vitamin E-like molecules potentiate the curcumin-induced suppression of Caco-2 cell proliferation
SAKUMA SatoruKohda T, Sakuma S, Fujimoto Y.
Kohda T, Sakuma S, Fujimoto Y.   6(1) 41-46   2016   [Refereed]


Toxicology and Applied Pharmacology   189(2) 96-99   2003
Archives of Biochemistry and Biophysics, Part B ; Nitric Oxide   5(1) 77-81   2001
Biochemical and Biophysical Research Communications   230(2) 476-479   1997

Books etc

OXYGEN RADICALS : Effect of tert-butyl hydroperoxide on cyclooxygenase and lipoxygenase metabolism of arachidonic acid in platelets
Elsevier Science Publishers   1992   
Effects of reactive oxygen species on cyclooxygenase and lipoxygenase metabolism of arachidonic acid in platelets
Frontiers of Reactive Oxygen Species in Biology and Medicine Elsevier Science B. V.   1994   
Life Style-Related Diseases of the Digestive System: Endocrine Disruptors Stimulate Lipid Accumulation in Target Cells Related to Metabolic Syndrome
Journal of Pharmacological Sciences   2007   

Research Grants & Projects

Long-term toxicities of environmental chemicals
Project Year: 2005   
Regulation of cyclooxygenase-2 by lipid derived substances in hepatic or colorectal cancer cells.
Project Year: 2005   
Regulatory mechanisms of lipid accumulation in tissues related to metabolic syndrome.
Project Year: 2005   
Synsthesis and removal of reactive oxygen species and peroxidative lipids
Project Year: 1990   
Regulatory mechanisms of biosynthesis of arachidonic acid derived bioactive metabolites.
Project Year: 1988