IN Yasuko

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Name
IN Yasuko
Affiliation
Osaka University of Pharmaceutical Sciences
Section
Faculty of Pharmaceutical Sciences
Job title
Lecturer

Research Areas

 
 

Education

 
 
 - 
1984
Faculty of Pharmaceutical Science, Osaka University of Pharmaceutical Sciences
 

Published Papers

 
Okitsu T, Nakahigashi H, Sugihara R, Fukuda I, Tsuji S, In Y, Wada A
Chemistry (Weinheim an der Bergstrasse, Germany)      Oct 2018   [Refereed]
Atsumi Sasayama, Keiko Akita, Hiroto Oya, Takashi Kikuchi, Yasuko In, Mihoyo Fujitake, Takeshi Yamada, Reiko Tanaka
ChemistrySelect   3 6056-6060   Jun 2018
© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Two novel chukrasone-type limonoids, Guianofruits A and B (1 and 2) were isolated from the fruit oil of Carapa guianensis AUBLET(Meliaceae), a traditional medicine in Brazil and Latin American co...
Higuchi K, Tani Y, Kikuchi T, In Y, Yamada T, Muraoka O, Tanaka N, Tanaka R
Chemistry, an Asian journal   12(23) 3000-3004   Dec 2017   [Refereed]
Kikuchi T, Horii Y, Maekawa Y, Masumoto Y, In Y, Tomoo K, Sato H, Yamano A, Yamada T, Tanaka R
The Journal of organic chemistry   82(19) 10611-10616   Oct 2017   [Refereed]
Igarashi Y, Matsuoka N, In Y, Kataura T, Tashiro E, Saiki I, Sudoh Y, Duangmal K, Thamchaipenet A
Organic letters   19(6) 1406-1409   Mar 2017   [Refereed]
Kikuchi T, Maekawa Y, Tomio A, Masumoto Y, Yamamoto T, In Y, Yamada T, Tanaka R
Steroids   115 9-17   Nov 2016   [Refereed]
Igarashi Y, Asano D, Sawamura M, In Y, Ishida T, Imoto M
Organic letters   18(7) 1658-1661   Apr 2016   [Refereed]
Xie C, Soeda Y, Shinzaki Y, In Y, Tomoo K, Ihara Y, Miyasaka T
Journal of neurochemistry   135(1) 19-26   Oct 2015   [Refereed]
Takashi Kikuchi, Yuki Masumoto, Yasuko In, Koji Tomoo, Takeshi Yamada, Reiko Tanaka
European Journal of Organic Chemistry   2015 4645-4649   Jul 2015
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. A new rearranged ergostane-type steroid, named eringiacetal A (1), together with known compound 2, were isolated from the fruiting bodies of Pleurotus eryngii (Pleurotaceae). Its structure was f...
Takanobu Inoue, Yuuki Matsui, Takashi Kikuchi, Takeshi Yamada, Yasuko In, Osamu Muraoka, Chie Sakai, Kiyofumi Ninomiya, Toshio Morikawa, Reiko Tanaka
Tetrahedron   71 2753-2760   May 2015
©2015 Elsevier Ltd. All rights reserved. Five novel phragmalin-type limonoids, carapanolides M-Q (1-5), together with two mexicanolide-type limonoids, carapanolides R-S (6-7), were isolated from the oil of Carapa guianensis AUBLET (Meliaceae) seed...
Inoue T, Matsui Y, Kikuchi T, In Y, Muraoka O, Yamada T, Tanaka R
Fitoterapia   96 56-64   Jul 2014   [Refereed]
Sogawa K, Minoura K, In Y, Ishida T, Taniguchi T, Tomoo K
Biopolymers   102(3) 288-295   May 2014   [Refereed]
Kim Y, In Y, Ishida T, Onaka H, Igarashi Y
Organic letters   15(14) 3514-3517   Jul 2013   [Refereed]
Inoue T, Matsui Y, Kikuchi T, In Y, Yamada T, Muraoka O, Matsunaga S, Tanaka R
Organic letters   15(12) 3018-3021   Jun 2013   [Refereed]
Okitsu T, Yumitate S, Sato K, In Y, Wada A
Chemistry (Weinheim an der Bergstrasse, Germany)   19(16) 4992-4996   Apr 2013   [Refereed]
Daisuke Saeki, Takeshi Yamada, Yasuko In, Tetsuya Kajimoto, Reiko Tanaka, Yota Iizuka, Takahisa Nakane, Akihito Takano, Kazuo Masuda
Tetrahedron   69 1583-1589   Feb 2013
Novel 5 lupane-type of triterpenois, i.e., 3β-acetoxy-18α, 19α-epoxylupan-21β-ol (1), 18α,19α-epoxy-21β- hydroxylupan-3-one (2), lup-18-ene-3,21-dione (3), lupa-18,21-dien-3β-yl acetate (4), and (17S)-17,18-seco-lup-19(21)-ene-3,18,22-trione (5), ...
Sogawa K, Okuda R, In Y, Ishida T, Taniguchi T, Minoura K, Tomoo K
Journal of biochemistry   152(3) 221-229   Sep 2012   [Refereed]
Paku KS, Umenaga Y, Usui T, Fukuyo A, Mizuno A, In Y, Ishida T, Tomoo K
The Biochemical journal   441(1) 237-245   Jan 2012   [Refereed]
Umenaga Y, Paku KS, In Y, Ishida T, Tomoo K
Biochemical and biophysical research communications   414(3) 462-467   Oct 2011   [Refereed]
Fukuyo A, In Y, Ishida T, Tomoo K
Journal of peptide science : an official publication of the European Peptide Society   17(9) 650-657   Sep 2011   [Refereed]
Yuji Tanaka, Takeshi Yamada, Yasuko In, Osamu Muraoka, Tetsuya Kajimoto, Reiko Tanaka
Tetrahedron   67 782-792   Jan 2011
A new gedunin, three new mexicanolides and three new phragmalin-type limonoids named Andirolides A (1), B (2), C (3), D (4), E (5), F (6), and G (7) were isolated from oil of the flower of Carapa guianensis Aublet (Meliaceae). Their absolute stere...
Naruto K, Minoura K, Okuda R, Taniguchi T, In Y, Ishida T, Tomoo K
FEBS letters   584(19) 4233-4236   Oct 2010   [Refereed]
Igarashi Y, Kim Y, In Y, Ishida T, Kan Y, Fujita T, Iwashita T, Tabata H, Onaka H, Furumai T
Organic letters   12(15) 3402-3405   Aug 2010   [Refereed]
Miyoko Kamigauchi, Yukiko Maekawa, Chisato Tode, Yasuko In, Toshimasa Ishida
Helvetica Chimica Acta   93 25-32   Feb 2010
The X-ray crystal analyses of the two 11-deoxy-didehydrohexahydrobenzo[c] phenanthridine-type alkaloid derivatives 3 and 4, derived from (±)-corynoline (1) and (+)-chelidonine (2), established their structures as (±)-(5bRS,12bRS)-5b,12b,13,14-tetr...
Takashi Okitsu, Daisuke Nakazawa, Akihiro Kobayashi, Masahiro Mizohata, Yasuko In, Toshimasa Ishida, Akimori Wada
Synlett   203-206   Feb 2010
An efficient approach to the synthesis of azaspiro compounds having dissymmetric dienone cores was achieved by ipso-iodocyclization of ethoxyethyl ether to alkynes. When the linker was an ether or an ester, domino iodocyclizaion/Diels-Alder reacti...
IN Yasuko, UCHIDA Masaru, WATANABE Masamichi, AIMI Norio, ISHIDA Toshimasa
Chemistry letters   38(11) 1024-1025   Nov 2009
Yasuko In, Masaru Uchida, Masamichi Watanabe, Norio Aimi, Norio Aimi, Toshimasa Ishida
Chemistry Letters   38(11) 1024-1025   Oct 2009
The coordination of six potassium ions to glycyrrhizin (1) is shown in a crystal: two crystallographically independent (K1 and K2) and four symmetry-translated potassium ions coordinate to the oxygen atoms of the sugar-linkage moiety, and the K1 a...
Sugino E, Nishiura C, Minoura K, In Y, Sumida M, Taniguchi T, Tomoo K, Ishida T
Biochemical and biophysical research communications   385(2) 236-240   Jul 2009   [Refereed]
Yamaguchi C, In Y, Wada S, Yamada T, Tokuda H, Tanaka R
Chemistry & biodiversity   6(7) 1093-1100   Jul 2009   [Refereed]
Miyoko Kamigauchi, Yukiko Maekawa, Yasuko In, Toshimasa Ishida
X-ray Structure Analysis Online   25 87-88   Jan 2009
The crystal structure of a hexahydrobenzo[c]phenanthridine-type alkaloid (d)-11-oxo-corynoline (1), 5b,6,7,12b,13,14- hexahydro-5b,13-dimethyl-[1,3]benzodioxolo[5,6-c]1,3-dioxolo[4,5-i] phenanthridine-6-one, is reported here. The crystal is orthor...
Miyoko Kamigauchi, Yuko Noda, Kinuko Iwasa, Yasuko In, Toshimasa Ishida
X-ray Structure Analysis Online   25 11-12   Jan 2009
The crystal structure of the racemic alkaloid (dl)-corynoloxine (1), 5b,6,7,12b,13,14-hexahydro-5b,13-dimethyl-6,14-epoxy-1,3-dioxolo[4,5-i][1,3]dioxolo[4,5]benzo[1,2-c]phenanthridine, is reported here. The crystal is orthorhombic, space group Pbc...
M. Kamigauchi, M. Kamigauchi, Y. Noda, Y. Noda, K. Iwasa, K. Iwasa, Y. In, Y. In, T. Ishida, T. Ishida
X-ray Structure Analysis Online   25 45-46   Jan 2009
Miyoko Kamigauchi, Yasuko In, Toshimasa Ishida
X-ray Structure Analysis Online   25 27-28   Jan 2009
The chemical structure of deN-corynoline (1), which was obtained by the cleavage of C-N bonds of corynoline, was clarified by X-ray crystal analysis to be 7-methyl-7-(4-methyl-benzo[1,3]dioxol-5-yl)-5,6,7,8-tetrahydronaphtho[2,3-d][1,3]dioxol-6-ol...
Mizuno A, In Y, Fujita Y, Abiko F, Miyagawa H, Kitamura K, Tomoo K, Ishida T
FEBS letters   582(23-24) 3439-3444   Oct 2008   [Refereed]
Hattori M, Sugino E, Minoura K, In Y, Sumida M, Taniguchi T, Tomoo K, Ishida T
Biochemical and biophysical research communications   374(1) 158-163   Sep 2008   [Refereed]
Synthesis of a novel alpha,alpha-disubstitute glycine, acyclobutylalanine
Yamada Takashi, Okumura Tomoka, Mizukoshi Rina, Murashima Takashi, Miyazawa Toshifumi, In Yasuko
JOURNAL OF PEPTIDE SCIENCE   14(8) 49   Aug 2008   [Refereed]
Synthesis and biological activities of endomorphin-2 analogues containing Pro mimics
Tsuda Yuko, Miyazaki Anna, Yamada Takashi, Isozaki Kaname, Shimohigashi Yasuyuki, Ambo Akihiro, Sasaki Yusuke, Minoura Katsuhiko, In Yasuko, Ishida Toshimasa, Okada Yoshio
JOURNAL OF PEPTIDE SCIENCE   14(8) 130   Aug 2008   [Refereed]
Tomoo K, Mukai Y, In Y, Miyagawa H, Kitamura K, Yamano A, Shindo H, Ishida T
Biochimica et biophysica acta   1784(7-8) 1059-1067   Jul 2008   [Refereed]
Sayaka Taji, Takeshi Yamada, Yasuko In, Shun Ichi Wada, Yoshihide Usami, Kazuo Sakuma, Reiko Tanaka
Helvetica Chimica Acta   90 2047-2057   Dec 2007
Three new lanostane-type triterpenoids, inonotsulides A, B, and C (1-3, resp.) were isolated from the sclerotia of Inonotus obliquus (PERS.: Fr.) (Japanese name: Kabanoanatake; Russian name: Chaga). Their structures were determined to be (20R,24S)...
Yasuko In, Toshimasa Ishida
Chemistry Letters   36 342-343   Feb 2007
A unique hydrophobic pore is generated by the self-assembly of Leu-Leu-Leu-NH2(1) in the crystal structure, in which the C-terminal amide groups induce the cylindrical arrangement of Leu side chains by intermolecular NH⋯O hydrogen bonds. This body...
IN Yasuko, ISHIDA Toshimasa
Chemistry letters   36(2) 342-343   Feb 2007
A unique hydrophobic pore is generated by the self-assembly of Leu–Leu–Leu–NH2 (1) in the crystal structure, in which the C-terminal amide groups induce the cylindrical arrangement of Leu side chains by intermol...
Yasuko In, Hirofumi Ohishi, Hiroo Miyagawa, Kunihiro Kitamura, Yasuhiro Igarashi, Toshimasa Ishida
Bulletin of the Chemical Society of Japan   79 126-133   Nov 2006
The absolute configuration of chainin (1), a polyene macrolide antibiotic, was determined by X-ray crystal analyses, and the conformational stability of planar 28-membered ring was confirmed by an ab initio quantum chemical calculation. The most p...
Li T, Tsuda Y, Minoura K, In Y, Ishida T, Lazarus LH, Okada Y
Chemical & pharmaceutical bulletin   54(6) 873-877   Jun 2006   [Refereed]
IN Yasuko, OHISHI Hirofumi, MIYAGAWA Hiroo, KITAMURA Kunihiro, IGARASHI Yasuhiro, ISHIDA Toshimasa
Bulletin of the Chemical Society of Japan   79(1) 126-133   Jan 2006
In Yasuko, Ohishi Hirofumi, Miyagawa Hiroo, Kitamura Kunihiro, Igarashi Yasuhiro, Ishida Toshimasa
Bulletin of the Chemical Society of Japan   79(1) 126-133   2006
The absolute configuration of chainin (1), a polyene macrolide antibiotic, was determined by X-ray crystal analyses, and the conformational stability of planar 28-membered ring was confirmed by an ab initio quantum chemical calculation. The...
Kazuhiro Yoshizawa, Yasuko In, Toshimasa Ishida, Takayuki Shioiri
Heterocycles   66(0) 667-674   Dec 2005
Preparation and X-Ray crystallographic analysis of the benzyl quaternary salts of nicotine and sparteine were described. © 2005 The Japan Institute of Heterocyclic Chemistry.
T. Fujimori, S. Yamada, H. Yasui, H. Sakurai, Y. In, T. Ishida
Journal of Biological Inorganic Chemistry   10 831-841   Dec 2005
Ever since it was proposed that reactive oxygen species (ROS) are involved in the pathogeneses of various diseases, superoxide dismutase (SOD)-mimetic complexes have been intensively studied. We prepared copper(II) aspirinate [Cu2(asp)4] from Cu(I...
Igarashi Y, In Y, Ishida T, Fujita T, Yamakawa T, Onaka H, Furumai T
The Journal of antibiotics   58(8) 523-525   Aug 2005   [Refereed]
Kamigauchi M, Noda Y, Nishijo J, Iwasaki K, Tobetto K, In Y, Tomoo K, Ishida T
Bioorganic & medicinal chemistry   13(5) 1867-1872   Mar 2005   [Refereed]
Yasuko In, Koji Tomoo, Toshimasa Ishida, Yasuhiko Sakamoto
Chem. Pharm. Bull   52(10) 1186-1189   Oct 2004
The (+)-enantiomer of modafinil [(RS)-2-(diphenylmethylsulfinyl)acetamide], a novel wake-promoting agent, was clarified to be S-configuration by X-ray crystal structure analysis. The crystal consists of two crystallographically independent conform...
Yasuko In, Shouitirou Kishima, Katsuhiko Minoura, Takeru Nose, Yasuyuki Shimohigashi, Toshimasa Ishida
Chem. Pharm. Bull   51(11) 1258-1263   Nov 2003
X-Ray crystal structures of four different fluorine-substituted phenylalanines (two mono- and two tri-substitutions) were analyzed to investigate the effect of fluorine atom on the association pattern of benzene rings. Although respective structur...
KAMIGAUCHI Miyoko, YOSHIDA Mayumi, NODA Yuko, NISHIJO Jujiro, IN Yasuko, TOMOO Koji, OHISHI Hirofumi, ISHIDA Toshimasa
Bulletin of the Chemical Society of Japan   76(3) 587-593   Mar 2003
Yasuko In, Hirofumi Ohishi, Toshimasa Ishida, Yasuhiro Igarashi
Chem. Commun.   3(14) 1692-1693   Jan 2003
The concerted interactions observed between five conjugated double bond CHs and four hydroxy Os in the crystal of chainin, a polyene macrolide antibiotic, clarified the existence of unprecedented, weak ≡C-H⋯O interactions, which is important for f...
Miyoko Kamigauchi, Mayumi Yoshida, Yuko Noda, Jujiro Nishijo, Yasuko In, Koji Tomoo, Hirofumi Ohishi, Toshimasa Ishida
Bull. Chem. Soc. Jpn   76(3) 587-593   Jan 2003
A possible relation between the stereostructure of (-)-(13aS)-tetrahydroberberine (1) and its enzymatic/chemical N-methylation, an important biosynthetic reaction to isoquinoline alkaloids in plants, was examined by CD spectroscopic, X-ray crystal...
Fumiaki Yokokawa, Fumiaki Yokokawa, Hirofumi Sameshima, Yasuko In, Katsuhiko Minoura, Toshimasa Ishida, Takayuki Shioiri
Tetrahedron   58(40) 8127-8143   Sep 2002
The first total synthesis of cis,cis-ceratospongamide (cyclo[L-Pro-L-Ile-Me-oxazoline-L-Phe-L-Pro-thiazole-L-Phe-]) was accomplished and confirmed by X-ray crystal analysis. The heating of cis,cis-ceratospongamide in DMSO converted it not to the t...
Atsushi Yamamoto, Koji Tomoo, Ken Ichi Matsugi, Tadaoki Hara, Yasuko In, Mitsuo Murata, Kunihiro Kitamura, Toshimasa Ishida
Biochimica et Biophysica Acta   1597 244-251   Jun 2002
In order to elucidate the substrate specificity of the Sn subsites (n=1-3) of cathepsin B, its crystal structure inhibited by E64c [(+)-(2S,3S)-3-(1-[N-(3-methylbutyl)amino]-leucylcarbonyl)oxirane-2- carboxylic acid] was analyzed by the X-ray diff...
Yasuko In, Hiroto Ono, Toshimasa Ishida
Chemical and Pharmaceutical Bulletin   50(5) 571-577   May 2002
As part of a series of elucidation of the structural features of peptides caused by C-terminal α-amidation, the crystal structures of H-Val-Gly-NH2, H-Ser-Phe-NH2, H-Gly-Tyr-NH2, and H-Pro-Tyr-NH2 hydrochloride salts were analyzed by the X-ray dif...
Reiko Tanaka, Kazuhiro Tsujimoto, Yasuko In, Toshimasa Ishida, Shunyo Matsunaga, Harukuni Tokuda, Osamu Muraoka
Tetrahedron   58(13) 2505-2512   Mar 2002
Two novel skeletal triterpene aldehydes, jezananals A (1) and B (2) were isolated from the stem bark of Picea jezoensis var. jezoensis (Pinaceae). Their absolute stereo structures were determined to be 21β-hydroxy-3β-methoxy-16(15→14)abeo-13R,14S-...
Yasuko In, Yasuko In, K. Minoura, H. Ohishi, T. Ishida, H. Minakata, M. Kamigauchi, M. Sugiura
Journal of Peptide Research   58 399-412   Dec 2001
In order to make clear the structural role of the C-terminal amide group of endomorphin-2 (EM2, H-Tyr-Pro-PhePhe-NH2), an endogenous μ-receptor ligand, in the biological function, the solution conformations of endomorphin-2 and its C-terminal free...
R. Tanaka, K. Tsujimoto, Y. In, T. Ishida, S. Matsunaga, Y. Terada
Journal of Natural Products   64(8) 1044-1047   Sep 2001
Three new epoxytriterpenes, 14β, 15β-epoxy-21β-hydroxyserratan-3-one (1), 13α, 14α-epoxy-21α-methoxyserratan-3-one (2), and 13α,14α-epoxy-3β-methoxyserratan-21β-ol (3), were isolated together with two known triterpenoids, 21α-methoxyserrat-13-en-3...
H. Ohtsu, R. Tanaka, Y. In, S. Matsunaga, H. Tokuda, H. Nishino
Planta Medica   67(1) 55-60   Mar 2001
Four known (1 - 3, 8) and four new abietane diterpenes, 15-hydroxy-8α,14α,12α,13α-diepoxyabietan-18-oic acid (4), 7α,8α,13β,14β-diepoxyabietan-18-oic acid (5), 18-nor-abieta-8,11,13-triene-4α,7α,15-triol (6), and abieta-8,11,13-triene-7α,15,18-tri...
Yasuko In, Mayumi Fujii, Yasuhiro Sasada, Toshimasa Ishida
Acta Cryst. B   57 72-81   Feb 2001
To elucidate the structural features of amino acids caused by the C-terminal α-amidation, the crystal structures of HCl salts of C-terminal amidated Ile, Val, Thr, Ser, Met, Trp, Gln and Arg were analysed and compared with those of their C-termina...
Miyoko Kamigauchi, Mayumi Yoshida, Kayoko Saiki, Makiko Sugiura, Jujiro Nishijo, Yasuko In, Toshimasa Ishida
Bull.Chem.Soc.Jpn   73(5) 1233-1241   May 2000
The conformational/physicochemical features of corycavidine (1), 5,7,8,15-tetrahydro-3,4-dimethoxy-6,15-dimethyl-[1,3]benzodioxolo[5,6-e] [2]benzazecin-14(6H)-one, an important protopine-type alkaloid that serves as the key intermetabolite in the ...
T. Tanaka, T. Azuma, X. Fang, S. Uchida, C. Iwata, T. Ishida, Y. In, N. Maezaki
Synlett   33-36   Jan 2000
We have developed a new sulfenylation reagent, 3-phenylsulfenyl-2-(N- cyanoimino)thiazolidine 3, that is readily available and stable upon storage. Compound 3 easily reacts with amines or thiols to give the corresponding sulfenamides or asymmetric...
Hironori Ohtsu, Reiko Tanaka, Yasuko In, Shunyo Matsunaga, Harukuni Tokuda, Hoyoku Nishino
Can.J.Chem   78(1) 31-40   Jan 2000
A new podocarpane diterpene, 7α, 15-dihydroxypodocarp-8(14)-en-13-one (1) and eight new abietane diterpenes, abiet-8(14)-en-7α, 13β,15,18- tetraol (2), 7α,13β,15-trihydroxyabiet-8(14)-en-18-oic acid (3), 13β,18- dihydroxyabiet-8(14)-en-7-one (4), ...
Tetsuaki Tanaka, Xie Fang, Tsutomu Azuma, Shuji Uchida, Toshimasa Ishida, Yasuko In, Chuzo Iwata, Naoyoshi Maezaki
Journal of the Chinese Chemical Society   47 865-868   Jan 2000
(S)-3-Acyl-4-diphenylmethyl-2-(N-cyanoimino)thiazolidine was found to be an effective enantioselective acylation reagent for racemic amines. 3-Benzoyl derivative was found to realize up to 79% ee upon acylation of (+)-1-phenylethylamine.
Yasuko In, Sayuri Tani, Toshimasa Ishida
Chem.Pharm.Bull   48(3) 374-381   Jan 2000
As part of tile series investigating tile structural features of C- terminal amidated amino acids and peptides, three crystal structures of Z- Gly-Phe-NH2, Tyr-Lys-NH2, and Asp-Phe-NH2were analyzed by the X-ray diffraction method, and their molecu...
IN Yasuko, TANI Sayuri, ISHIDA Toshimasa
Chemical and Pharmaceutical Bulletin   48(3) 374-381   2000
As part of the series investigating the structural features of C-terminal amidated amino acids and peptides, three crystal structures of Z-Gly-Phe-NH2, Tyr-Lys-NH2, and Asp-Phe-NH2 were analyzed by the X-ray diffra...
Reiko Tanaka, Tsuyoshi Kumagai, Yasuko In, Toshimasa Ishida, Hoyoku Nishino, Shunyo Matsunaga
Tetrahedron Letters   40(35) 6415-6418   Aug 1999
A CHCl3extract of the stem bark of Picea jezoensis var. hondoensis (Pinaceae) afforded two triterpenoids named piceanonols A and B with a novel 14(13 → 12)abeo-12αH-serratane skeleton. Extensive NMR studies, MS spectral analyses and X-ray crystall...
Y. In, Toshimasa Ishida, K. Takesako
J. Peptide Res   53(5) 492-500   Jul 1999
A structural feature of aureobasidins, cyclic depsipeptide antibiotics produced by Aureobasidium pullulans R106, is the N-methylation of four out of seven amide bonds. In order to investigate possible relationship between the molecular conformatio...
Mitsunobu Doi, Fumiyoshi Shinozaki, Yasuko In, Toshimasa Ishida, Daisuke Yamamoto, Miyoko Kamigauchi, Makiko Sugiura, Yasumasa Hamada, Kohfuku Kohda, Takayuki Shioiri
Biopolymers   49(6) 459-469   May 1999
Ascidiacyclamide, a cytotoxic cyclic peptide from tunicate, is composed of unusual amino acids and has a repeated sequence, c[-thiazole-D-Val- oxazoline-L-lle-]2 ([Ile]ASC). The symmetric chemical structure has been assumed to be correlated with t...
Toshimasa Ishida, Reijirou Manabe, Yasuko In, Hajime Takashima, Kunihiro Kitamura, Akio Wakahara
Bull. Chem. Soc. Jpn   72(5) 947-954   May 1999
Copper((]G0002[))Ion-Catalyzed and Molecukar Packing-Dependent Dimerization of Pyridoxsal 5-Phosphate-Pyridoxamine 5-Phosphate Sciff Base as a Structure Model for in Vitro Transformation of Amino Acid by Pyridoxal 5-phosphate : X-ray Crystal Struc...
Ishida Toshimasa, Manabe Reijirou, In Yasuko, Takashima Hajime, Kitamura Kunihiro, Wakahara Akio
Bulletin of the Chemical Society of Japan   72(5) 947-954   1999
X-Ray crystal structures of the end products, obtained by in vitro Cu(II)-mediated transamination reaction of <FONT SIZE="-2">L</FONT>-alanine by the vitamin B6 coenzyme, show that the Cu(II) complex of pyridoxal 5-phosphate&ndash;pyridoxamine 5-p...

Misc

 
沖津貴志, 杉原僚祐, 俟野文隆, 中東光, 福田一起, 尹康子, 和田昭盛
ヨウ素   (19) 64‐65   2016
SOGAWA Koushirou, OKUDA Ryouhei, MINOURA Katsuhiko, IN Yasuko, ISHIDA Toshimasa, TANIGUCHI Taizo, TOMOO Koji
Peptide science : proceedings of the ... Japanese Peptide Symposium   2011 165-168   Mar 2012
IN Yasuko, MINOURA Katsuhiko, ISHIDA Toshimasa, FUJIOKA Shio, TAKEDA Misai, MURASHIMA Takashi, YAMADA Takashi
Peptide science : proceedings of the ... Japanese Peptide Symposium   2011 205-208   Mar 2012
YAMADA Takashi, FUJIOKA Shio, TAKEDA Misai, GOHDA Shin, MURASHIMA Takashi, IN Yasuko
Peptide science : proceedings of the ... Japanese Peptide Symposium   2010    Mar 2011
MINOURA Katsuhiko, NARUTO Keiko, OKUDA Ryouhei, TANIGUCHI Taizo, IN Yasuko, ISHIDA Toshimasa, TOMOO Koji
Peptide science : proceedings of the ... Japanese Peptide Symposium   2010    Mar 2011
YAMADA Takashi, OKUMURA Tomoko, MIZUKOSHI Rina, MURASHIMA Takashi, MIYAZAWA Toshifumi, IN Yasuko
Peptide science : proceedings of the ... Japanese Peptide Symposium   2008 143-144   Mar 2009
TSUDA Yuko, MIYAZAKI Anna, YAMADA Takashi, ISOZAKI Kaname, SHIMOHIGASHI Yasuyuki, AMBO Akihiro, SASAKI Yusuke, MINOURA Katsuhiko, IN Yasuko, ISHIDA Toshimasa, OKADA Yoshio
Peptide Science   2008 227-228   Mar 2009
SUGINO Etsuko, HATTORI Masaki, MINOURA Katsuhiko, IN Yasuko, SUMIDA Miho, TANIGUCHI Taizo, TOMOO Koji, ISHIDA Toshimasa
Peptide science : proceedings of the ... Japanese Peptide Symposium   2008 331-334   Mar 2009
YAMADA Takashi, OKUMURA Tomoko, MIZUKOSHI Rina, TSUBOI Daisuke, MURASHIMA Takashi, MIYAZAWA Toshifumi, IN Yasuko
Peptide science : proceedings of the ... Japanese Peptide Symposium   2007 129-132   Mar 2008
YAMADA Takashi, HIRANO Koichiro, HANYU Masayuki, MURASHIMA Takashi, MIYAZAWA Toshifumi, IN Yasuko, ISHIDA Toshimasa
Peptide science : proceedings of the ... Japanese Peptide Symposium   2006 89-90   Mar 2007
IN Yasuko, MINOURA Katsuhiko, ISHIDA Toshimasa
Peptide science : proceedings of the ... Japanese Peptide Symposium   2004 427-430   Mar 2005
YOKOKAWA Fumiaki, SHIOIRI Takayuki, IN Yasuko, MINOURA Katsuhiro, ISHIDA Toshimasa
Peptide Science(2002)   2002 41-44   Feb 2003
IN Yasuko, MINOURA Katsuhiko, ISHIDA Toshimasa, MINAKATA Hiroyuki, KAMIGAUCHI Miyoko, SUGIURA Makiko
Peptide Science 2000   2000(313-316) 313-316   Mar 2001
Molesular Conformation of Aureobasidin A, a Potent Antifungal Cyclic Depsipeptide : X-Ray Structure Anaiysis
Peptide Science   349-352   1999
IN Yasuko, ISHIDA Toshimasa, TAKESAKO Kazutoh
Peptide science : proceedings of the ... Japanese Peptide Symposium   1998 349-352   Oct 1998
Isomerization of ddimeric 2,9-disubstituted 1-oxaquinolizidine alkaloids and structural revision of araguspongines B and E, isolated from a marine sponge of xestospongia SP.
Heterocycles   47 195-203   1998
1H NMR and X-ray conformational analyses of (+)-corydalic acid methyl ester, a6,7-secoberbine alakaloid
J. Chem. Soc. , Perkin Trans. 2,   631-636   1997
Structure Analyses for Asymmetric Derivatives of Ascidiacyclamide by X-ray Diffraction and NMR Spectroscopy
Peptide Chemistry   405-408   1997
SHINOZAKI Fumiyoshi, IN Yasuko, DOI Mitsunobu, YAMAMOTO Daisuke, KAMIGAUCHI Miyoko, SUGIURA Makiko, ISHIDA Toshimasa, HAMADA Yasumasa, SHIOIRI Takayuki
Peptide chemistry : proceedings of the ... Symposium on Peptide Chemistry   1996 405-408   Oct 1996

Conference Activities & Talks

 
槌田智裕, 土屋孝弘, 尹康子, 箕浦克彦, 谷口泰造, 友尾幸司
日本薬学会年会要旨集(CD-ROM)   Mar 2018   
菊地崇, 堀井祐衣, 前川由季菜, 桝本有季, 尹康子, 友尾幸司, 佐藤寛泰, 山野昭人, 山田剛司, 田中麗子
日本生薬学会年会講演要旨集   25 Aug 2017   
友尾幸司, 澤田怜, 田宮祥恵, 二神康介, 山田剛司, 箕浦克彦, 尹康子, 中村達也, 吾妻正章, 谷口泰造
日本薬学会年会要旨集(CD-ROM)   Mar 2017   
西岡紗和子, 松本京之助, 尹康子, 宮本勝城, 辻坊裕, 友尾幸司
日本薬学会年会要旨集(CD-ROM)   Mar 2017   
沖津貴志, 杉原遼祐, 俟野文隆, 中東光, 福田一起, 尹康子, 和田昭盛
反応と合成の進歩シンポジウム講演要旨集   21 Oct 2016   
友尾幸司, 知名秀泰, 宮野菜央, 河野広朗, 尹康子, 箕浦克彦, 宮本勝城, 土屋孝弘, 辻坊裕
日本薬学会年会要旨集(CD-ROM)   Mar 2016   
沖津貴志, 杉原僚祐, 俟野文隆, 中東光, 福田一起, 尹康子, 和田昭盛
ヨウ素   2016   
菊地崇, 桝本有季, 尹康子, 友尾幸司, 山田剛司, 田中麗子
香料・テルペンおよび精油化学に関する討論会講演要旨集   5 Sep 2015   
菊地崇, 桝本有季, 尹康子, 友尾幸司, 山田剛司, 田中麗子
日本生薬学会年会講演要旨集   31 Aug 2015   
宮野菜央, 五十嵐智子, 河野広朗, 友尾幸司, 尹康子, 箕浦克彦, 宮本勝城, 土屋孝弘, 辻坊裕
日本薬学会年会要旨集(CD-ROM)   Mar 2015   
曾川甲子郎, 奥田良平, 箕浦克彦, 尹康子, 宮崎杏奈, 谷口泰造, 石田寿昌, 友尾幸司
日本薬学会年会要旨集(CD-ROM)   Mar 2014   
生野将史, 宮本陽菜, 曾川甲子郎, 箕浦克彦, 尹康子, 谷口泰造, 石田寿昌, 友尾幸司
日本薬学会年会要旨集(CD-ROM)   Mar 2014   
田中麗子, 井上喬允, 松井勇樹, 菊地崇, 尹康子, 村岡修, 山田剛司
日本生薬学会年会講演要旨集   20 Aug 2013   
曾川甲子郎, 宮崎杏奈, 箕浦克彦, 尹康子, 谷口泰造, 友尾幸司
日本薬学会年会要旨集(CD-ROM)   Mar 2013   
臼井常悟, 斎藤慧, 尹康子, 友尾幸司, 石田寿昌, 宮本勝城, 辻坊祐
日本薬学会年会要旨集(CD-ROM)   Mar 2013   
KIM Youngju, 尹康子, 石田寿昌, 尾仲宏康, 五十嵐康弘
天然有機化合物討論会講演要旨集(Web)   1 Sep 2012   
五十嵐康弘, 浅野大介, 宮永賢, 奥直也, 降旗一夫, 尹康子, 石田寿昌, 井本正哉, 済木育夫
天然有機化合物討論会講演要旨集(Web)   1 Sep 2012   
須佐匡樹, 土屋孝弘, 箕浦克彦, 尹康子, 友尾幸司, 谷口泰造, 辻坊裕, 石田寿昌
日本薬学会年会要旨集   5 Mar 2012   
曾川甲子郎, 奥田良平, 箕浦克彦, 尹康子, 友尾幸司, 石田寿昌
日本薬学会年会要旨集   5 Mar 2012   
篠原愛花, 向高弘, 上垣内みよ子, 尹康子, 友尾幸司, 石田寿昌
日本薬学会年会要旨集   5 Mar 2012   
Igarashi Yasuhiro, Asano Daisuke, Miyanaga Satoshi, Oku Naoya, Furihata Kazuo, In Yasuko, Ishida Toshimasa, Imoto Masaya, Saiki Ikuo
Symposium on the Chemistry of Natural Products, symposium papers   2012   
Metastasis is the major cause of cancer mortality. During the process of metastasis, invasion and migration are critical steps for cancer cells to spread from the primary tumor and establish the secondary tumor. Therefore, suppression of these ste...
Kim Youngju, In Yasuko, Ishida Toshimasa, Onaka Hiroyasu, Igarashi Yasuhiro
Symposium on the Chemistry of Natural Products, symposium papers   2012   
Natural products are an important source of novel therapeutics with enormous structural diversity exceeding our imagination. Especially, Type I polyketide synthetase (PKS) produces highly diverse structures with variation of chain length, cyclizat...
梅永優, 朴琴順, 福代愛, 尹康子, 友尾幸司, 石田寿昌
日本薬学会年会要旨集   5 Mar 2011   
曾川甲子郎, 尹康子, 友尾幸司, 石田寿昌
日本薬学会年会要旨集   5 Mar 2011   
齋藤慧, 森岡秀彰, 尹康子, 友尾幸司, 石田寿昌, 高田千秋, 宮本勝城, 辻坊裕
日本薬学会年会要旨集   5 Mar 2011   
奥田良平, 鳴戸佳子, 箕浦克彦, 尹康子, 谷口泰造, 友尾幸司, 石田寿昌
日本薬学会年会要旨集   5 Mar 2011   
石井公一朗, 尹康子, 友尾幸司, 石田寿昌, 宮本勝城, 辻坊裕
日本薬学会年会要旨集   5 Mar 2011   
福代愛, 朴琴順, 水野敦雄, 尹康子, 友尾幸司, 石田寿昌
日本薬学会年会要旨集   5 Mar 2010   
朴琴順, 水野敦雄, 尹康子, 友尾幸司, 石田寿昌
日本薬学会年会要旨集   5 Mar 2010   
上垣内みよ子, 岩佐衣子, 尹康子, 石田寿昌
日本薬学会年会要旨集   5 Mar 2010   
鳴戸佳子, 箕浦克彦, 尹康子, 谷口泰造, 友尾幸司, 石田寿昌
日本薬学会年会要旨集   5 Mar 2010   
田中裕治, 山田剛司, 尹康子, 村岡修, 田中麗子
日本薬学会年会要旨集   5 Mar 2010   
木挽友博, 土屋孝弘, 箕浦克彦, 尹康子, 友尾幸司, 谷口泰造, 辻坊裕, 石田寿昌
日本薬学会年会要旨集   5 Mar 2010   
池宮安葵子, 天見勇太, 向井康博, 尹康子, 友尾幸司, 石田寿昌
日本薬学会年会要旨集   5 Mar 2010   
津田裕子, 安保明博, 佐々木有亮, 箕浦克彦, 尹康子, 石田寿昌, 岡田芳男
日本薬学会年会要旨集   5 Mar 2010   
坂本亜沙美, 山田剛司, 尹康子, 村岡修, 田中麗子
日本薬学会年会要旨集   5 Mar 2010   
河井千佳, 美馬将司, 尹康子, 友尾幸司, 石田寿昌, 岩本隆宏
日本薬学会年会要旨集   5 Mar 2010   
友尾幸司, 石井公一朗, 三木康裕, 森岡秀彰, 尹康子, 石田寿昌, 宮本勝城, 辻坊裕
日本結晶学会年会講演要旨集   2010   
田中裕治, 山田剛司, 尹康子, 田辺元三, 村岡修, 田中麗子
香料・テルペンおよび精油化学に関する討論会講演要旨集   7 Nov 2009   
田中裕治, 山田剛司, 尹康子, 田辺元三, 村岡修, 田中麗子
食品薬学シンポジウム講演要旨集   21 Oct 2009   
相見則郎, 内田勝, 尹康子, 石田寿昌, 北川勲
食品薬学シンポジウム講演要旨集   21 Oct 2009   
五十嵐康弘, 尹康子, 石田寿昌, 菅由紀子, 藤田剛司, 岩下孝, 田畠広和, 尾仲宏康, 古米保
天然有機化合物討論会講演要旨集   1 Sep 2009   
杉野恵津子, 服部正幹, 箕浦克彦, 尹康子, 澄田美保, 谷口泰造, 友尾幸司, 石田寿昌
日本薬学会年会要旨集   5 Mar 2009   
沖津貴志, 中澤大祐, 小林亮広, 溝畑雅裕, 尹康子, 石田寿昌, 和田昭盛
日本薬学会年会要旨集   5 Mar 2009   
Igarashi Yasuhiro, In Yasuko, Ishida Toshimasa, Kan Yukiko, Fujita Tsuyoshi, Iwashita Takashi, Tabata Hirokazu, Onaka Hiroyasu, Furumai Tamotsu
Symposium on the Chemistry of Natural Products, symposium papers   2009   
Actinomycetes have provided a diverse array of bioactive secondary metabolites. In particular, those belonging to the genus Streptomyces have been the most promising source of chemically diverse secondary metabolites. Their high capacity of second...
尹康子, 相見則郎, 内田勝, 中村英雄, 北川勲, 宮川博夫, 石田寿昌
日本薬学会年会要旨集   5 Mar 2008   
美馬将司, 友尾幸司, 岩本隆宏, 喜多紗斗美, 宮川博夫, 尹康子, 石田寿昌
日本薬学会年会要旨集   5 Mar 2008   
山田隆己, 森悠紀, 平野公一朗, 村嶋貴之, 宮澤敏文, 尹康子, 石田寿昌
日本化学会講演予稿集   12 Mar 2007   
尹康子, 石田寿昌
日本薬学会年会要旨集   5 Mar 2007   
生理活性ペプチドにおけるC-末端アミド基の構造化学的研究 Endomorphin-2及びそのフリー体の溶液中でのコンフォメーション解析
尹 康子, 箕浦 克彦, 石田 寿昌
日本薬学会年会要旨集   Mar 2004   
イソキノリン型化合物corynoloxineの立体構造及びその細胞接着阻害活性
野田 有子, 近藤 真介, 福西 恵, 上垣内 みよ子, 西庄 重次郎, 尹 康子, 石田 寿昌
日本薬学会年会要旨集   Mar 2002   
海洋産生物活性ペプチドcis,cis-Ceratospongamide(CEA)の結晶構造とその熱異性化体D-allo-Ile-CEAの溶液構造の解析
尹 康子, 箕浦 克彦, 石田 寿昌, 横川 文明, 鮫島 博文, 塩入 孝之
日本薬学会年会要旨集   Mar 2002   
Tanaka Reiko, Tsujimoto Kazuhiro, In Yasuko, Matsunaga Shunyo, Muraoka Osamu
Symposium on the Chemistry of Natural Products, symposium papers   1995   
Previously, we have reported on the structures and anti-tumor-promoting activity of three triterpeneoids bearing a novel skeltal system of 14(13→12)abeo-12αH-serratane, for which we named "picane", isolated from the stem bark of Picea jezoensis Ca...
アンジオテンシン変換酵素(ACE)阻害剤の結晶構造
尹 康子
日本薬学会年会要旨集   Mar 1986   
ヒスタミンH2-受容体拮抗作用を有する化合物の結晶構造
尹 康子
日本薬学会年会要旨集   Mar 1985   

Research Grants & Projects

 
Elucidation the phyoicochemical feature of bioacties peptides cauced by the C-terminal amidation
Project Year: 1999   
Structure-Activity Relationships of Bioactive Peptides
Project Year: 1992   
Structure-Activity Rlationship of a Cytotoxic Cyclic Peptide from Marine origin based on X-Ray Crystal Structure
Project Year: 1991