AlphaGUARD is a low-effective volume detector and one of the most popular portable radon monitors which is currently available. This study investigated whether AlphaGUARD can accurately measure the variable indoor radon levels. The consistency of the radon-concentration data obtained by AlphaGUARD is evaluated against simultaneous measurements by two other monitors (each similar to 10 times more sensitive than AlphaGUARD). When accurately measuring radon concentration with AlphaGUARD, we found that the net counts of the AlphaGUARD were required of at least 500 counts, < 25% of the relative percent difference. AlphaGUARD can provide accurate measurements of radon concentration for the world average level (similar to 50 Bq m(-3)) and the reference level of workplace (1000 Bq m(-3)), using integrated data over at least 3 h and 10 min, respectively.