MISC

1999年

ヘテロ分岐シクロデキストリンの合成とその性質

応用糖質科学
  • 濱保 健一
  • ,
  • 原 浩司
  • ,
  • 藤田 孝輝
  • ,
  • 橋本 仁
  • ,
  • 松田 一葉
  • ,
  • 岡田 安代
  • ,
  • 谷本 敏子
  • ,
  • 小泉 京子
  • ,
  • 中野 博文
  • ,
  • 北畑 寿美雄

46
2
開始ページ
217
終了ページ
225
記述言語
日本語
掲載種別
DOI
10.5458/jag.46.217
出版者・発行元
The Japanese Society of Applied Glycoscience

Hetero-branched cyclodextrins (CDs) were synthesized by transglycosylation or the reverse action of several enzymes such as βββ-galactosidases, α-galactosidases, α-mannosidases, lysozyme and R-Nacetylhexosaminidase. Their structures were analyzed by methylation, FAB-MS, and NMR spectroscopies. β-Galactosidase and a-galactosidase from microorganisms synthesized hetero-branched CDs, of which the galactose residues were linked at side chains of the branched CDs. But these enzymes could not synthesize galactosyl-CDs, directly linked to the CD ring. However, α-galactosidase from coffee bean and α-mannosidase and N-acetylhexosaminidase from jack bean could bind galactosyl, mannosyl and N-acetylglucosaminyl residues directly to the CD rings, respectively, by transglycosylation or reverse action. The effects of the side-chain residues in branched CDs, on solubility, hemolytic activity, and inclusion reactions with 6-O-α-D-glucosyl-CDs, 6-O-α-D-galactosyl-CDs, and 6-O-α-Dmannosyl-CDs, were examined.

リンク情報
DOI
https://doi.org/10.5458/jag.46.217
CiNii Articles
http://ci.nii.ac.jp/naid/10008259068
CiNii Books
http://ci.nii.ac.jp/ncid/AN10453916
URL
http://id.ndl.go.jp/bib/4785936
URL
https://jlc.jst.go.jp/DN/JALC/00086373500?from=CiNii
ID情報
  • DOI : 10.5458/jag.46.217
  • ISSN : 1344-7882
  • ISSN : 1880-7291
  • CiNii Articles ID : 10008259068
  • CiNii Books ID : AN10453916

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