2004年3月
The fifth gene of the iol operon of Bacillus subtilis, iolE, encodes 2-keto-myo-inositol dehydratase.
Microbiology (Reading, England)
- ,
- ,
- ,
- ,
- ,
- 巻
- 150
- 号
- Pt 3
- 開始ページ
- 571
- 終了ページ
- 580
- 記述言語
- 英語
- 掲載種別
- Scientific Journal
- DOI
- 10.1099/mic.0.26768-0
The myo-inositol catabolism pathway of Bacillus subtilis has not been fully characterized but was proposed to involve step-wise multiple reactions that finally yielded acetyl-CoA and dihydroxyacetone phosphate. It is known that the iolABCDEFGHIJ operon is responsible for the catabolism of inositol. IolG catalyses the first step of myo-inositol catabolism, the dehydrogenation of myo-inositol, producing 2-keto-myo-inositol (inosose). The second step was thought to be the dehydration of inosose. Genetic and biochemical analyses of the iol genes led to the identification of iolE, encoding the enzyme for the second step of inositol catabolism, inosose dehydratase. The reaction product of inosose dehydratase was identified as D-2,3-diketo-4-deoxy-epi-inositol.
- リンク情報
- ID情報
-
- DOI : 10.1099/mic.0.26768-0
- ISSN : 1350-0872
- CiNii Articles ID : 80016531214
- PubMed ID : 14993306