HARAGUCHI Koichi

J-GLOBAL         Last updated: Jun 22, 2019 at 08:46
 
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Name
HARAGUCHI Koichi
Affiliation
Daiichi University,College of Pharmaceutical Sciences
Section
Faculty of Pharmaceutical SciencesCourse of Pharmaceutical Technology
Degree
(BLANK)(Kyushu University)

Research Interests

 
 

Research Areas

 
 

Academic & Professional Experience

 
1979
 - 
1990
Daiichi College of Pharmaceutical Sciences, Research Assistant.
 
1990
 - 
1996
Daiichi College of Pharmaceutical Sciences, Lecturer
 
1996
 - 
2001
Daiichi College of Pharmaceutical Sciences, Assistant Professor
 
2001
   
 
- Daiichi College of Pharmaceutical Sciences, Professor
 

Education

 
 
 - 
1977
Faculty of Pharmaceutical Science, Tokyo University of Science
 
 
 - 
1979
Graduate School, Division of Pharmaceutical Sciences, Kyushu University
 

Published Papers

 
Levels and profiles of long-chain perfluoroalkyl carboxylic acids in Pacific cod from 14 sites in the North Pacific Ocean.
Fujii Y, Tuda H, Kato Y, Kimura O, Endo T, Harada KH, Koizumi A, Haraguchi K.
Environmental Pollution   247 312-318   2019   [Refereed]
Comparison of radiocesium and stable isotope ratios of carbon and nitrogen among three stocks of Pacific cod (Gadus macrocephalus) around Hokkaido, Japan.
Nakamura T, Tanaka T, Kimura O, Fujii Y, Haraguchi K, Endo T.
Marine Pollution Bulletin   127 39-44   2018   [Refereed]
Different profiles of naturally produced and anthropogenic organohalogens in the livers of cetaceans from the Sea of Japan and the North Pacific Ocean.
Fujii Y, Kato Y, Kozai M, Matsuishi T, Harada KH, Koizumi A, Kimura O, Endo Haraguchi K.
Marine Pollution Bulletin   127 39-44   2018   [Refereed]
Contamination trends and factors affecting the transfer of hexabromocyclododecane diastereomers, tetrabromobisphenol A, and 2,4,6-tribromophenol to breast milk in Japan.
Fujii Y, Kato Y, Masuda N, Harada KH, Koizumi A, Haraguchi K.
Environmental Pollution   237 936-943   2018   [Refereed]
Tissue-specific bioaccumulation of long-chain perfluorinated carboxylic acids and halogenated methylbipyrroles in Dall's porpoises (Phocoenoides dalli) and harbor porpoises (Phocoena phocoena) stranded in northern Japan.
Fujii Y, Kato Y, Sakamoto K, Matsuishi T, Harada K, Koizumi A, Kimura O, Endo T, Haraguchi K.
Science of The Total Environment   616-617 554-563   2018   [Refereed]
Growth-related in non-essential and essential metals in the liver of star-spotted smooth-hounds (dogfish) Mustelus manazo from the northern region of Japan.
Endo T, Kimura O, Terasaki M, Fujii Y, Haraguchi K, Ohta C, Koga N, Kato Y.
Marine Environmental Research   131 156-161   2017   [Refereed]
Possible mechanism for the polychlorinated biphenyl induced liver-selective accumulation of thyroxine in rats. Kato Y, Fujii A, Haraguchi K, Fujii Y, Atobe K, Tetsuya, Endo T, Kimura O, Koga N, Ohta C, Yamada S, Degawa M.
Kato Y, Fujii A, Haraguchi K, Fujii Y, Atobe K, Tetsuya, Endo T, Kimura O, Koga N, Ohta C, Yamada S, Degawa M.
The Journal of Toxicological Sciences   42(663) 669   2017   [Refereed]
Long-term trends in dietary intake of perfluoroalkyl carboxylic acids in relation to their serum concentration in two regions in Japan from 1979 to 2011.
Fujii Y, Harada KH, Haraguchi K, Koizumi A.
Chemosphere   176 165-174   2017   [Refereed]
Effect of quercetin on the uptake and efflux of aristolochic acid I from Caco-2 cell monolayers.
Kimura O, Fujii Y, Haraguchi K, Ohta C, Koga N, Kato Y, Endo T.
Journal of pharmacy and pharmacology   68 883-889   2016   [Refereed]
Metal concentrations in the liver and stable isotope ratios of carbon and nitrogen in the muscle of silvertip shark (Carcharhinus albimarginatus) culled off Ishigaki island, Japan: Changes with growth.
Endo T, Kimura O, Ohta C, Koga N, Kato Y, Fujii Y, Haraguchi K.
PLoS One   11 e0147797   2016   [Refereed]
Relationship between mercury, organochlorine compounds and stable isotope ratios of carbon and nitrogen in yellowfin tuna (Thunnus albacares) taken from different regions of the Pacific and Indian Oceans.
Endo T, Kimura O, Fujii Y, Haraguchi K,
Ecological Indicators   69 340-347   2016   [Refereed]
Levels, profiles and dietary sources of hydroxylated PCBs and hydroxylated and methoxylated PBDEs in Japanese women serum samples.
Haraguchi K, Ito Y, Takagi M, Fujii Y, Harada KH, Koizumi A.
Environment International   97 155-162   2016   [Refereed]
Bisphenol AF as an inducer of estrogen receptorβ (ERβ): Evidence for anti-estrogenic effects at higher concentrations in human breast cancer cells.
Okazaki H, Takeda S, Kakizoe K, Taniguchi A, Tokuyasu M, Himeno T, Ishii H, Kohro-Ikeda E, Haraguchi K, Watanabe K, Aramaki H.
Biological & Pharmaceutical Bulletin   40 1909-1916   2016   [Refereed]
Relationships among mercury concentration and stable isotope ratios of carbon and nitrogen in the scalp hair of residents from seven countries: effects of marine fish and C4 plants consumption.
Endo T, Hayasaka M, Ogasawara H, Kimura O, Kotaki Y, Haraguchi K.
PLoS One   10 e0128149   2015   [Refereed]
Mercury, cadmium, zinc and copper concentrations and stable isotope ratios of carbon and nitrogen in tiger sharks (Galeocerdo cuvier) culled off Ishigaki Island, Japan.
Endo T, Kimura O, Ogasawara H, Ohta C, Koga N, Kato Y, Haraguchi K.
Ecological Indicators   55 86-93   2015   [Refereed]
Distribution and excretion of 2,2′,3,4′,5,5′,6-heptachlorobiphenyl (CB187) and its metabolites in rats and guinea pigs.
Ohta C, Haraguchi K, Kato Y, Endo T, Kimura O, Koga N.
Chemosphere   118 5-11   2015   [Refereed]
Long-chain perfluoroalkyl carboxylic acids in Pacific cods from coastal areas in northern Japan: a major source of human dietary exposure.
Fujii Y, Sakurada T, Harada K, Koizumi A, Kimura O, Endo T, Haraguchi K.
Environmental Pollution   199 35-41   2015   [Refereed]
Detection of antibodies to human T-cell leukemia virus types 1 and 2 in breast milk from east Asian women.
Matsubara F, Sagara Y, Kato Y, Haraguchi K, Harada K, Koizumi A.
Biological and Pharmaceutical Bulletin   37 311-314   2014   [Refereed]
Temporal trend and age-dependent serum concentration of phenolic organohalogen contaminants in Japanese men during 1989-2010.
Fujii Y, Harada KH, Hitomi T, Kobayashi H, Koizumi A, Haraguchi K.
Environmental Pollution   185 228-233   2014   [Refereed]
Dietary exposure to phenolic and methoxylated organohalogen contaminants in relation to their concentrations in breast milk and serum in Japan.
Fujii Y, Nishimura E, Kato Y, Harada KH, Koizumi A, Haraguchi K.
Environment International   63 19-25   2014   [Refereed]
3,3′,4,4′-Tetrachlorobiphenyl-mediated decrease of serum thyroxine level in C57BL/6 and DBA/2 mice occurs mainly through enhanced accumulation of thyroxine in the liver.
Kato Y, Haraguchi K, Onishi M, Ikushiro S, Endo T, Ohta C, Koga N, Yamada S, Degawa M.
Biological and Pharmaceutical Bulletin,   37 504-509   2014   [Refereed]
Carrier-mediated uptake of nobiletin, a citrus polymethoxyflavonoid, in human intestinal Caco-2 cells
Kimura O, Ohta C, Koga N, Haraguchi K, Kato Y, Endo T,
Food Chemistry   154 145-150   2014   [Refereed]
Uptake of aristolochic acid I into Caco-2 cells by monocarboxylic acid transporters.
Kimura O, Haraguchi K, Ohta C, Koga N, Kato Y, Endo T.
Biological and Pharmaceutical Bulletin,   37 1475-1479   2014   [Refereed]
Stable isotope ratios of carbon, nitrogen and oxygen in killer whales (Orcinus orca) stranded on the coast of Hokkaido, Japan.
Endo T, Kimura O, Sato R, Kobayashi M, Matsuda A, Matsuishi T, Haraguchi K.
Marine Pollution Bulletin   86 238-243   [Refereed]

Misc

 
Metabolite of 2, 2', 4', 5-tetrabromobiphenyl, 3-methylsufony1-2, 2', 4'. 5-tetrabromobiphenyl, a potent inducer of CYP2B1/2 in rat
Xenobiotica   32, 289-393    2002
The changes of PCBs and PCDFs as well as symptoms in Yusho patients for 30 years.
┣DBFukuoka Acta Medica(/)-┫DB,92,167-176(2001)   92(5) 167-176   2001
Species differences in the in vitro metabolism of 2, 4, 5, 2', 3', 4'-hexachlorobiphenyl.
┣DBFukuoka Acta Medica(/)-┫DB,92,149-157(2001)   92(5) 149-157   2001
Koichi HARAGUCHI, Tetsuya ENDO, Masakatsu SAKATA, Yoshito MASUDA, Mark SIMMONDS
┣DBJ. Food Hyg. Soc. Japan(/)-┫DB,41,287-296(2000)   41(4) 287-296   2000
Archives of Environmental Contamination and Toxicology   35(1) 121-128   1998
Tissue distribution of methylsulfonyl metabolites derived from Kanechlor 400 in mice
88(5) 157-161   1997
Comparative study on formation of hydroxy and sulfur-containing metabolites from different chlorinated biphenyls with 2,5-substitution in rats
Drug Metabolism and Disposition   25(7) 845-852   1997
Change of PCDF and PCB concentrations in the blood of Yucheng and Yusho patients for 25 years
Fukuoka Acta Medica   86(5) 178-183   1995
Tissue retention of hydroxy and methylsulfonyl metabolites of 2,2', 4,4'-tetrachlorobiphenyl in rats
Fukuoka Acta Medica   86(5) 163-168   1995

Research Grants & Projects

 
Comtamination survey of marine products
Project Year: 1999   
Study on Environmental Pollution of Toxic Chemicals
Project Year: 1991 - 1994
Study on Metabolism and Toxicity of Polyhalogeneted Biphenyl and related compound.
Project Year: 1994