Apr, 2016 - Mar, 2018
Are high serum sclerostin levels, bone formation inhibitory factor, associated with a decreased risk of vascular calcification? A long term cohort study for Multi-organ association
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research Grant-in-Aid for Challenging Exploratory Research
- Grant number
- 16K15384
- Japan Grant Number (JGN)
- JP16K15384
- Authorship
- Coinvestigator(s)
- Grant amount
-
- (Total)
- 3,770,000 Japanese Yen
- (Direct funding)
- 2,900,000 Japanese Yen
- (Indirect funding)
- 870,000 Japanese Yen
We investigated the relationship of serum sclerositn levels to vascular calcification events at caroid artery using 290 women longitudinally. Serum sclerositn levels were measured using frozen serum obtained in the 15-year follow-up survey. The number of vascular calcification events which occurred during the 10-year and 20-year follow-up survey was twenty-seven. The event rates of the lowest, middle, highest tertile of sclerostin levels were 10.4%, 10.3%, 7.2%, respectively (p-value for trend test=0.446). Odds ratio of 1SD increase in log-transformed sclerositn for vascular calcification events neither indicated statistical significance (Odds ratio, 1.00, p-value of 0.988).
- Link information
- ID information
-
- Grant number : 16K15384
- Japan Grant Number (JGN) : JP16K15384