MASUTANI Hiroshi

J-GLOBAL         Last updated: Dec 7, 2018 at 19:28
 
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Name
MASUTANI Hiroshi
E-mail
h.masutanitenriyorozu-u.ac.jp
URL
https://www.researchgate.net/profile/Hiroshi_Masutani
Affiliation
Tenri Health Care University
Job title
Professor
Degree
Doctor of Medicine, PhD(Kyoto University)

Profile

We investigate the molecular mechanism of thioredoxin binding protein-2 (TBP-2/ Txnip) and alpha-arrestin proteins which attract much attention as multifunctional regulators in the pathogenesis of viral infection and diseases including cancer and Diabetes Mellitus. Our goal is to elucidate the pathogenesis of these diseases and develop approaches against these diseases and Alzheimer's disease. We also study redox and stress signaling focusing on thioredoxin family proteins.
Research Focus
1) Investigation of the molecular mechanism of cancer suppression by Txnip
2) Development of drugs against Alzheimer's disease by small molecular compounds
3) Investigation of molecular biology of alpha arrestin family proteins

http://jglobal.jst.go.jp/public/200901024441064610
https://www.researchgate.net

Research Areas

 
 

Academic & Professional Experience

 
Apr 2017
 - 
Today
Professor, Tenri Health Care University
 
1992
   
 
- assistant professor
 
2004
   
 
- associate professor
 

Education

 
 
 - 
1992
Graduate School, Division of Medicine, Kyoto University
 
 
 - 
1985
Faculty of Medicine, Kyoto University
 

Published Papers

 
Recent advances regarding role of thioredoxin, Txnip, and ARRDC3 in cancer and other diseases
Hiroshi MASUTANI and Cristiane Lumi HIRATA
Bulletin of Tenri Health Care University      2018   [Refereed][Invited]
Anti-Inflammatory Thioredoxin Family Proteins for Medicare, Healthcare and Aging Care.
Yodoi J, Matsuo Y, Tian H, Masutani H, Inamoto T.
Nutrients   9(10)    2017   [Refereed]
Differential expression of thioredoxin binding protein-2/Txnip in human placenta: Possible involvement of hypoxia in its suppression during early pregnancy.
Mogami H, Yura S, Kondoh E, Masutani H, Yodoi J, Konishi I.
J Obstet Gynaecol Res.   43(1) 50-56   2017   [Refereed]
MASUTANI Hiroshi
Arch Biochem Biophys   595 88-93   Apr 2016   [Refereed]
Y. Matsuo; K. Irie; H. Kiyonari; H. Okuyama; H. Nakamura; A. Son; D.A. Lopez-Ramos; H. Tian; S.-I. Oka; K. Okawa; S. Kizaka-Kondoh; H. Masutani; J. Yodoi
Antioxidants and Redox Signaling   18(11) 1263-1272   Apr 2013   [Refereed]
Nagano S, Takahashi Y, Yamamoto K, Masutani H, Fujiwara N, Urushitani M, Araki T
Human molecular genetics   24(12) 3427-3439   Jun 2015   [Refereed]
Yashiro M, Tsukahara H, Matsukawa A, Yamada M, Fujii Y, Nagaoka Y, Tsuge M, Yamashita N, Ito T, Yamada M, Masutani H, Yodoi J, Morishima T
Critical care medicine   41(1) 171-181   Jan 2013   [Refereed]
F.T. Ogata; W.L. Batista; A. Sartori; T.F. Gesteira; H. Masutani; R.J. Arai; J. Yodoi; A. Stern; H.P. Monteiro
PLoS ONE   8(12) e84588   2013   [Refereed]
Taketani Y, Kinugasa K, Kitajima R, Nishiumi S, Ashida H, Nakamura H, Fujita T, Kanzaki K, Masutani H, Yodoi J
Bioscience, biotechnology, and biochemistry   78(7) 1221-1230   2014   [Refereed]
Y. Taketani; K. Kinugasa; S. Furukawa; H. Nakamura; R. Otsuki; H. Yasuda; T. Fujita; K. Kanzaki; H. Masutani; J. Yodoi
Bioscience, Biotechnology and Biochemistry   75(10) 1872-1879   Oct 2011   [Refereed]
K. Asami; A. Inagaki; T. Imura; S. Sekiguchi; K. Fujimori; H. Masutani; J. Yodoi; S. Satomi; N. Ohuchi; M. Goto
PLoS ONE   8(8) e70259   2013   [Refereed]
K. Nishizawa; H. Nishiyama; Y. Matsui; T. Kobayashi; R. Saito; H. Kotani; H. Masutani; S. Oishi; Y. Toda; N. Fujii; J. Yodoi; O. Ogawa
Carcinogenesis   32(10) 1459-1466   Oct 2011   [Refereed]
S. Lim; H. Ashida; R. Watanabe; K. Inai; Y.-S. Kim; K. Mukougawa; H. Fukuda; K. Tomizawa; K. Ushiyama; H. Asao; M. Tamoi; H. Masutani; S. Shigeoka; J. Yodoi; A. Yokota
Plant Molecular Biology   76(3-5) 335-344   Jul 2011   [Refereed]
Masutani H, Yoshihara E, Masaki S, Chen Z, Yodoi J
Journal of clinical biochemistry and nutrition   50(1) 23-34   Jan 2012   [Refereed]
Masaki S, Masutani H, Yoshihara E, Yodoi J
PloS one   7(6) e39900   2012   [Refereed]
S.-I. Oka; W. Liu; E. Yoshihara; M.K. Ahsan; D.A.L. Ramos; A. Son; H. Okuyama; L. Zhang; H. Masutani; H. Nakamura; J. Yodoi
Critical Care Medicine   38(12) 2345-2351   Dec 2010   [Refereed]
Z. Chen; E. Yoshihara; A. Son; Y. Matsuo; H. Masutani; K. Sugie; M. Maeda; J. Yodoi
Immunology Letters   131(1) 11-18   Jun 2010   [Refereed]
E. Yoshihara; Z. Chen; Y. Matsuo; H. Masutani; J. Yodoi
Methods in enzymology   474 67-82   2010   [Refereed]
R. Watanabe; H. Nakamura; H. Masutani; J. Yodoi
Pharmacology and Therapeutics   127(3) 261-270   Sep 2010   [Refereed]
R. Watanabe; H. Nakamura; H. Masutani; J. Yodoi
Pharmacology and Therapeutics   129(2) 239-   2011   [Refereed]
E. Yoshihara; S. Fujimoto; N. Inagaki; K. Okawa; S. Masaki; J. Yodoi; H. Masutani
Nature Communications   1(8) 127   Nov 2010   [Refereed]
Z. Chen; D.A. Lopez-Ramos; E. Yoshihara; Y. Maeda; H. Masutani; K. Sugie; M. Maeda; J. Yodoi
Leukemia   25(3) 440-448   2011   [Refereed]
Mochizuki M, Kwon YW, Yodoi J, Masutani H
Antioxidants & redox signaling   11(12) 2957-2971   Dec 2009   [Refereed]
S.-I. Oka; E. Yoshihara; A. Bizen-Abe; W. Liu; M. Watanabe; J. Yodoi; H. Masutani
Endocrinology   150(3) 1225-1234   Mar 2009   [Refereed]
Okuyama H, Yoshida T, Son A, Oka S, Wang D, Nakayama R, Masutani H, Nakamura H, Nabeshima Y, Yodoi J
Antioxidants & redox signaling   11(10) 2585-2593   Oct 2009   [Refereed]
Masutani H, Otsuki R, Yamaguchi Y, Takenaka M, Kanoh N, Takatera K, Kunimoto Y, Yodoi J
Antioxidants & redox signaling   11(5) 949-962   May 2009   [Refereed]
A. Son; H. Nakamura; H. Okuyama; S.-I. Oka; E. Yoshihara; W. Liu; Y. Matsuo; N. Kondo; H. Masutani; Y. Ishii; T. Iyoda; K. Inaba; J. Yodoi
European Journal of Immunology   38(5) 1358-1367   May 2008   [Refereed]
F. Zhou; M. Gomi; M. Fujimoto; M. Hayase; T. Marumo; H. Masutani; J. Yodoi; N. Hashimoto; K. Nozaki; Y. Takagi
Brain Research   1272 62-70   May 2009   [Refereed]
M.K. Ahsan; H. Okuyama; Y. Hoshino; S. Oka; H. Masutani; J. Yodoi; H. Nakamura
Antioxidants & redox signaling   11(10) 2573-2584   Oct 2009   [Refereed]
H. Okuyama; A. Son; K. Ahsan; H. Masutani; H. Nakamura; J. Yodoi
IUBMB Life   60(10) 656-660   Oct 2008   [Refereed]
M. Mochizuki; Y.-W. Kwon; J. Yodoi; H. Masutani
Antioxidants and Redox Signaling   11(12) 2957-2971   Dec 2009   [Refereed]
S. Matsuoka; H. Tsuchiya; T. Sakabe; Y. Watanabe; Y. Hoshikawa; A. Kurimasa; H. Itamochi; T. Harada; N. Terakawa; H. Masutani; J. Yodoi; G. Shiota
Cancer Science   99(12) 2485-2490   Dec 2008   [Refereed]
R.J. Arai; F.T. Ogata; W.L. Batista; H. Masutani; J. Yodoi; V. Debbas; O. Augusto; A. Stern; H.P. Monteiro
Toxicology and Applied Pharmacology   233(2) 227-237   Dec 2008   [Refereed]
H. Masutani; R. Otsuki; Y. Yamaguchi; M. Takenaka; N. Kanoh; K. Takatera; Y. Kunimoto; J. Yodoi
Antioxidants and Redox Signaling   11(5) 949-962   May 2009   [Refereed]
K.K. Dutta; Y. Zhong; Y.-T. Liu; T. Yamada; S. Akatsuka; Q. Hu; M. Yoshihara; H. Ohara; M. Takehashi; T. Shinohara; H. Masutani; J. Onuki; S. Toyokuni
Cancer Science   98(12) 1845-1852   Dec 2007   [Refereed]
A.M. Kaimul; H. Nakamura; H. Masutani; J. Yodoi
Free Radical Biology and Medicine   43(6) 861-868   Sep 2007   [Refereed]
Y. Takeuchi; W. Nomura; T. Ohdate; S. Tamasu; H. Masutani; K. Murata; S. Izawa; J. Yodoi; Y. Inoue
Applied Microbiology and Biotechnology   75(6) 1393-1399   Jul 2007   [Refereed]
H. Okuyama; T. Yoshida; A. Son; S.-I. Oka; D. Wang; R. Nakayama; H. Masutani; H. Nakamura; Y.-I. Nabeshima; J. Yodoi
Antioxidants and Redox Signaling   11(10) 2585-2593   2009   [Refereed]
Y. Hoshino; K. Shioji; H. Nakamura; H. Masutani; J. Yodoi
Antioxidants and Redox Signaling   9(6) 689-699   Jun 2007   [Refereed]
Y. Inoue; W. Nomura; Y. Takeuchi; T. Ohdate; S. Tamasu; A. Kitaoka; Y. Kiyokawa; H. Masutani; K. Murata; Y. Wakai; S. Izawa; J. Yodoi
Applied and Environmental Microbiology   73(5) 1672-1675   Mar 2007   [Refereed]
D. Wang; H. Masutani; S.-I. Oka; T. Tanaka; Y. Yamaguchi-Iwai; H. Nakamura; J. Yodoi
Journal of Biological Chemistry   281(11) 7384-7391   Mar 2006   [Refereed]
S.-I. Oka; H. Masutani; W. Liu; H. Horita; D. Wang; S. Kizaka-Kondoh; J. Yodoi
Endocrinology   147(2) 733-743   Feb 2006   [Refereed]
Thioredoxin-binding protein-2 (TBP-2): Its potential roles in the aging process
T. Yoshida; N. Kondo; S.-I. Oka; M.K. Ahsan; T. Hara; H. Masutani; H. Nakamura; J. Yodoi
BioFactors   27(1-4) 47-51   2006   [Refereed]
H. Nakamura; H. Masutani; J. Yodoi
Seminars in Cancer Biology   16(6) 444-451   Dec 2006   [Refereed]
N. Kondo; H. Nakamura; H. Masutani; J. Yodoi
Antioxidants and Redox Signaling   8(9-10) 1881-1890   Sep 2006   [Refereed]
D. Wang; H. Masutani; J. Yodoi
IUBMB Life   58(11) 670-673   Nov 2006   [Refereed]
M. Kobayashi-Miura; K. Shioji; Y. Hoshino; H. Masutani; H. Nakamura; J. Yodoi
American Journal of Physiology - Heart and Circulatory Physiology   292(5) H2040-H2050   2007   [Refereed]
S.-I. Oka; W. Liu; H. Masutani; H. Hirata; Y. Shinkai; S.-I. Yamada; T. Yoshida; H. Nakamura; J. Yodoi
FASEB Journal   20(1) 121-123   Jan 2006   [Refereed]
T. Yoshida; H. Nakamura; H. Masutani; J. Yodoi
Annals of the New York Academy of Sciences   1055 1-12   Dec 2005   [Refereed]
K.K. Dutta; Y. Nishinaka; H. Masutani; S. Akatsuka; T.T. Aung; T. Shirase; W.-H. Lee; Y. Yamada; H. Hiai; J. Yodoi; S. Toyokuni
Laboratory Investigation   85(6) 798-807   Jun 2005   [Refereed]
M. Tanito; H. Masutani; Y.-C. Kim; M. Nishikawa; A. Ohira; J. Yodoi
Investigative Ophthalmology and Visual Science   46(3) 979-987   Mar 2005   [Refereed]
R.J. Arai; H. Masutani; J. Yodoi; V. Debbas; F.R. Laurindo; A. Stern; H.P. Monteiro
Biochemical and Biophysical Research Communications   348(4) 1254-1260   2006   [Refereed]
M. Tanito; Y.-W. Kwon; N. Kondo; J. Bai; H. Masutani; H. Nakamura; J. Fujii; A. Ohira; J. Yodoi
Journal of Neuroscience   25(9) 2396-2404   Mar 2005   [Refereed]
M.K. Ahsan; H. Masutani; Y. Yamaguchi; Y.-C. Kim; K. Nosaka; M. Matsuoka; Y. Nishinaka; M. Maeda; J. Yodoi
Oncogene   25(15) 2181-2191   2006   [Refereed]
Y. Nishinaka; H. Masutani; S.-I. Oka; Y. Matsuo; Y. Yamaguchi; K. Nishio; Y. Ishii; J. Yodoi
Journal of Biological Chemistry   279(36) 37559-37565   Sep 2004   [Refereed]
H. Masutani; J. Bai; Y.-C. Kim; J. Yodoi
Molecular Neurobiology   29(3) 229-242   Jun 2004   [Refereed]
H. Masutani; Y. Yamaguchi; R. Otsuki; N. Kanoh; Y. Kunimoto; K. Murata; J. Yodoi
Journal of Clinical Biochemistry and Nutrition   37(2) 45-53   2005   [Refereed]
Y. Matsuo; Y. Nishinaka; S. Suzuki; M. Kojima; S. Kizaka-Kondoh; N. Kondo; A. Son; J. Sakakura-Nishiyama; Y. Yamaguchi; H. Masutani; Y. Ishii; J. Yodoi
Archives of Biochemistry and Biophysics   423(1) 81-87   Mar 2004   [Refereed]
Y. Nishinaka; A. Nishiyama; H. Masutani; S.-I. Oka; K.Md. Ahsan; Y. Nakayama; Y. Ishii; H. Nakamura; M. Maeda; J. Yodoi
Cancer Research   64(4) 1287-1292   Feb 2004   [Refereed]
H. Masutani; S. Ueda; J. Yodoi
Cell Death and Differentiation   12(SUPPL. 1) 991-998   2005   [Refereed]
M. Tanito; H. Nakamura; Y.-W. Kwon; A. Teratani; H. Masutani; K. Shioji; C. Kishimoto; A. Ohira; R. Horie; J. Yodoi
Antioxidants and Redox Signaling   6(1) 89-97   Feb 2004   [Refereed]
Critical roles of thioredoxin in nerve growth factor-mediated signal transduction and neurite outgrowth in PC12 cells
J. Bai; H. Nakamura; Y.-W. Kwon; I. Hattori; Y. Yamaguchi; Y.-C. Kim; N. Kondo; S.-I. Oka; S. Ueda; H. Masutani; J. Yodoi
Journal of Neuroscience   23(2) 503-509   Jan 2003   [Refereed]
H. Kadowaki; H. Nishitoh; F. Urano; C. Sadamitsu; A. Matsuzawa; K. Takeda; H. Masutani; J. Yodoi; Y. Urano; T. Nagano; H. Ichijo
Cell Death and Differentiation   12(1) 19-24   2005   [Refereed]
T. Shibata; T. Yamada; M. Kondo; N. Tanahashi; K. Tanaka; H. Nakamura; H. Masutani; J. Yodoi; K. Uchida
Biochemistry   42(47) 13960-13968   Dec 2003   [Refereed]
K. Shioji; H. Nakamura; H. Masutani; J. Yodoi
Antioxidants and Redox Signaling   5(6) 795-802   Dec 2003   [Refereed]
T. Yoshida; S.-I. Oka; H. Masutani; H. Nakamura; J. Yodoi
Antioxidants and Redox Signaling   5(5) 563-570   Oct 2003   [Refereed]
Y.-W. Kwon; H. Masutani; H. Nakamura; Y. Ishii; J. Yodoi
Biological Chemistry   384(7) 991-996   Jul 2003   [Refereed]
T. Shibata; T. Yamada; T. Ishii; S. Kumazawa; H. Nakamura; H. Masutani; J. Yodoi; K. Uchida
Journal of Biological Chemistry   278(28) 26046-26054   Jul 2003   [Refereed]
Y.-C. Kim; Y. Yamaguchi; N. Kondo; H. Masutani; J. Yodoi
Oncogene   22(12) 1860-1865   Mar 2003   [Refereed]
K. Shioji; C. Kishimoto; H. Nakamura; H. Masutani; Z. Yuan; S.-I. Oka; J. Yodoi
Circulation   106(11) 1403-1409   Sep 2002   [Refereed]
T. Tanaka; F. Hosoi; Y. Yamaguchi-Iwai; H. Nakamura; H. Masutani; S. Ueda; A. Nishiyama; S. Takeda; H. Wada; G. Spyrou; J. Yodoi
EMBO Journal   21(7) 1695-1703   Apr 2002   [Refereed]
Y.-W. Kwon; S. Ueda; M. Ueno; J. Yodoi; H. Masutani
Journal of Biological Chemistry   277(3) 1837-1844   Jan 2002   [Refereed]
Change of redox status and modulation by thiol replenishment in retinal photooxidative damage
M. Tanito; A. Nishiyama; T. Tanaka; H. Masutani; H. Nakamura; J. Yodoi; A. Ohira
Investigative Ophthalmology and Visual Science   43(7) 2392-2400   Jul 2002   [Refereed]
Thioredoxin superfamily and thioredoxin-inducing agents
K. Hirota; H. Nakamura; H. Masutani; J. Yodoi
Annals of the New York Academy of Sciences   957 189-199   May 2002   [Refereed]
Cytoprotective effect of thioredoxin against retinal photic injury in mice
M. Tanito; H. Masutani; H. Nakamura; A. Ohira; J. Yodoi
Investigative Ophthalmology and Visual Science   43(4) 1162-1167   Apr 2002   [Refereed]
M. Tanito; H. Masutani; H. Nakamura; S.I. Oka; A. Ohira; J. Yodoi
Neuroscience Letters   326(2) 142-146   Jun 2002   [Refereed]
A. Orii; H. Masutani; T. Nikaido; Y.-L. Zhai; K. Kato; M. Kariya; I. Konishi; J. Yodoi; S. Fujii
Journal of Clinical Endocrinology and Metabolism   87(8) 3754-3759   Aug 2002   [Refereed]
J. Yodoi; H. Nakamura; H. Masutani
Biological Chemistry   383(3-4) 585-590   Mar 2002   [Refereed]
Matsumoto K, Masutani H, Nishiyama A, Hashimoto S, Gon Y, Horie T, Yodoi J
Biochemical and biophysical research communications   295(3) 663-667   Jul 2002   [Refereed]
T. Sasada; H. Nakamura; H. Masutani; S. Ueda; H. Sono; A. Takabayashi; J. Yodoi
Molecular Immunology   38(10) 723-732   Feb 2002   [Refereed]
S. Ueda; H. Nakamura; H. Masutani; T. Sasada; A. Takabayashi; Y. Yamaoka; J. Yodoi
Molecular Immunology   38(10) 781-791   Feb 2002   [Refereed]
H. Nakamura; H. Masutani; J. Yodoi
Antioxidants and Redox Signaling   4(3) 455-464   Jun 2002   [Refereed]
S. Ueda; H. Masutani; H. Nakamura; T. Tanaka; M. Ueno; J. Yodoi
Antioxidants and Redox Signaling   4(3) 405-414   Jun 2002   [Refereed]
Thioredoxin. Overview.
Masutani H, Yodoi J
Methods in enzymology   347 279-286   2002   [Refereed]
K. Matsumoto; H. Masutani; A. Nishiyama; S. Hashimoto; Y. Gon; T. Horie; J. Yodoi
Biochemical and Biophysical Research Communications   295(3) 663-667   2002   [Refereed]
H. Masutani; J. Yodoi
Methods in Enzymology   347 279-286   2002   [Refereed]
Y.-C. Kim; H. Masutani; Y. Yamaguchi; K. Itoh; M. Yamamoto; J. Yodoi
Journal of Biological Chemistry   276(21) 18399-18406   May 2001   [Refereed]
Redox regulation by the human thioredoxin system
J. Yodoi; H. Masutani; H. Nakamura
BioFactors   15(2-4) 107-111   2001   [Invited]
Oxidative stress and redox imbalance in acetaminophen toxicity.
H. Masutani
The pharmacogenomics journal   1(3) 165-166   2001   [Refereed]
Redox control of cellular function by thioredoxin; a new therapeutic direction in host defence
Y. Nishinaka; H. Nakamura; H. Masutani; J. Yodoi
Archivum Immunologiae et Therapiae Experimentalis   49(4) 285-292   2001   [Refereed]
Involvement of thioredoxin in the regulation of growth hormone secretion in rat pituitary cell cultures
I. Hata; Y. Shigematsu; Y. Ohshima; H. Tsukahara; K. Fujisawa; M. Hiraoka; H. Nakamura; H. Masutani; J. Yodoi; F. Kotsuji; M. Sudo; M. Mayumi
American Journal of Physiology - Endocrinology and Metabolism   281(2 44-2) E269-E274   2001   [Refereed]
A. Nishiyama; H. Masutani; H. Nakamura; Y. Nishinaka; J. Yodoi
IUBMB Life   52(1-2) 29-33   2001   [Refereed]
Y. Nishinaka; H. Masutani; H. Nakamura; J. Yodoi
Redox Report   6(5) 289-295   2001   [Refereed]
H. Dekigai; H. Nakamura; J. Bai; M. Tanito; H. Masutani; K. Hirota; H. Matsui; M. Murakami; J. Yodoi
Free Radical Research   35(1) 23-30   2001   [Refereed]
Oxidative stress response and signaling in hematological malignancies and HIV infection
H. Masutani
International Journal of Hematology   71(1) 25-32   2000   [Refereed]
T. Tanaka; H. Nakamura; A. Nishiyama; F. Hosoi; H. Masutani; H. Wada; J. Yodoi
Free Radical Research   33(6) 851-855   2000   [Refereed]
M. Ueno; Y. Matsutani; H. Nakamura; H. Masutani; M. Yagi; H. Yamashiro; H. Kato; T. Inamoto; A. Yamauchi; R. Takahashi; Y. Yamaoka; J. Yodoi
Immunology Letters   75(1) 15-20   2000   [Refereed]
M. Ueno; H. Masutani; R.J. Arai; A. Yamauchi; K. Hirota; T. Sakai; T. Inamoto; Y. Yamaoka; J. Yodoi; T. Nikaido
Journal of Biological Chemistry   274(50) 35809-35815   Dec 1999   [Refereed]

Misc

 
MATSUI MAKOTO, TOMIOKA RYO, HOTARI FUKUKO, NAGAYAMA SHIGEMI, MASUTANI HIROSHI
金沢医科大学雑誌   39(2) 49   Oct 2014
MATSUI MAKOTO, TOMIOKA RYO, HOASHI FUKUKO, NAGAYAMA SHIGEMI, MASUTANI HIROSHI
免疫性神経疾患に関する調査研究 平成25年度 総括・分担研究報告書   53-54   2014
MATSUI MAKOTO, TOMIOKA RYO, HOASHI FUKUKO, NAGAYAMA SHIGEMI, MASUTANI HIROSHI
金沢医科大学雑誌   38(3/4) 155-156   Dec 2013
YASHIRO MASATO, TSUKAHARA HIROKAZU, MATSUKAWA AKIHIRO, YAMADA MUTSUKO, FUJII YOSUKE, NAGAOKA YOSHIHARU, TSUGE MITSURU, YAMASHITA NOBUKO, ITO TOSHIHIRO, YAMADA MASAO, MASUTANI HIROSHI, YODOI JUNJI, MORISHIMA TSUNEO
岡山医学会雑誌   125(2) 109-112 (J-STAGE)   2013
MATSUI MAKOTO, TOMIOKA RYO, HOASHI FUKUKO, ARAYA SHIN'ICHI, NAGAYAMA SHIGEMI, MASUTANI HIROSHI
免疫性神経疾患に関する調査研究 平成24年度 総括・分担研究報告書   123-124   2013
MASAKI SATOSHI, YODOI JUNJI, MASUTANI HIROSHI
日本酸化ストレス学会学術集会プログラム・抄録集   65th 55   Jun 2012
MATSUI MAKOTO, ARAYA SHIN'ICHI, HOASHI FUKUKO, NAGAYAMA SHIGEMI, MASUTANI HIROSHI
日本神経免疫学会学術集会抄録集   24th 125   2012
Deficiency of Thioredoxin binding protein-2 enhances TGF-beta signaling.
正本聡, 淀井淳司, 増谷弘
第71 回日本癌学会学術集会, 札幌,2012 年9 月19-21日      2012   [Refereed]
Therapeutic effect of cytolytic anti-pan HLA class II mAb on Hodgkin, \nNon Hodgkin lymphoma and adult T cell Leukemia.
松岡周二, 石井保之, 八木田秀雄, 増谷弘, 前田道之, 杉本耕一, 荒瀬尚, 大辻奈穂美, 阿部雅明, 樋野興夫汀
第71 回日本癌学会学術集会      Sep 2012   [Refereed]
MASUTANI HIROSHI
医学のあゆみ   239(3) 231   Oct 2011
ASHIDA HIROKI, LIM SOON, WATANABE RIE, INAI KOJI, KIM YUN-SOO, MUKAIGAWA KEIKO, FUKUDA HIROKAZU, TAMOI MASAHIRO, MASUTANI HIROSHI, SHIGEOKA SHIGERU, YODOI JUNJI, YOKOTA AKIHO
日本植物生理学会年会要旨集   52nd 129   Mar 2011
YOSHIHARA EIJI, FUJIMOTO SHIMPEI, INAGAKI NOBUYA, OKAWA KATSUYA, MASAKI SO, YODOI JUNJI, MASUTANI HIROSHI
生化学   ROMBUNNO.1S11P-3   2011
Deficiency of Thioredoxin binding protein-2 (TBP-2) enhances TGF-β signaling and contributes to TGF-β-induced epithelial to mesenchymal transition.
正木 聡, 淀井淳司, 増谷 弘
第34回日本分子生物学会年会, 横浜, 12月, 2011.      2011   [Refereed]
ASHIDA HIROKI, TAMOI MASAHIRO, FUKUDA HIROKAZU, WATANABE RIE, SOON LIM, INAI KOJI, MUKAIGAWA KEIKO, YAMAKAWA HIRONOBU, KATO MASAO, USHIYAMA KEIICHI, MASUTANI HIROSHI, SHIGEOKA SHIGERU, YODOI JUNJI, YOKOTA AKIHO
バイオテクノロジーシンポジウム予稿集   28th 56-57   Sep 2010
MATSUO YOSHIYUKI, MASUTANI HIROSHI, YODOI JUNJI
日本酸化ストレス学会学術集会プログラム・抄録集   63rd 80   Jun 2010
YOSHIHARA EIJI, FUJIMOTO SHIMPEI, INAGAKI NOBUYA, YODOI JUNJI, MASUTANI HIROSHI
糖尿病   53(Supplement 1) S.94   Apr 2010
NISHIZAWA KOJI, NISHIYAMA HIROYUKI, MASUTANI HIROSHI, MATSUI YOSHIYUKI, WATABE JUN, SAITO RYOICHI, OGAWA OSAMU
日本泌尿器科学会雑誌   101(2) 201   Feb 2010
MASUTANI HIROSHI, YOSHIHARA EIJI, FUJIMOTO SHIMPEI, INAGAKI NOBUYA
生化学   ROMBUNNO.1W15-5   2010
MATSUO YOSHIYUKI, DORYS LOPEZ, YODOI JUNJI, MASUTANI HIROSHI
生化学   ROMBUNNO.2P-0188   2010
MASUTANI HIROSHI
がん研究に係わる特定領域研究研究報告集録 平成21年度   161   2010
Increased susceptibility to LPS-induced liver injury in mice deficient in the oxidoreductase TMX
松尾禎之,Dorys Lopez ,淀井淳司,増谷弘
第33 回日本分子生物学会 年会・第83 回日本生化学会大会合同大会、神戸、2010 年12 月      2010   [Refereed]
Differential roles of Annexin A1 (ANXA1/lipocortin-1/lipomodulin) and thioredoxin binding protein-2 (TBP-2/VDUP1/TXNIP) in glucocorticoid singaling of HTLV-1-transformed T cells,
Chen Zhe ,吉原栄治,Dorys Lopez-Ramos ,増谷 弘,杉江勝治,前田道之,淀井淳司
第33 回日本分子生物学会年会・第83 回日本生化 学会大会合同大会、神戸、2010 年12 月      2010   [Refereed]
Thiordoxin binding protein-2 (TBP-2) is a potential prognostic and therapeutic target for Adult T-cell leukemia
Chen Zhe ,Dorys Lopez-Ramos ,吉原栄治,前田裕弘,増谷 弘,杉江勝治,前田道之,淀 井淳司
第69 回日本癌学会学術総会、大 阪、2010 年9 月      2010   [Refereed]
NAKAMURA HAJIME, AHSAN MD KAIMUL, OKUYAMA HIROAKI, MASUTANI HIROSHI, YODOI JUNJI
消化器と免疫   (45) 172-175   Mar 2009
MASUTANI HIROSHI
がん研究に係わる特定領域研究研究報告集録 平成20年度   164   2009
Thioredoxin binding protein-2/Txnip is a key regulatory molecule in insulin resistance and type 2 diabetes.
吉原栄治,藤本新平,稲垣暢也,淀井淳司,増谷弘
第32 回分子生物学会、 横浜、2 0 0 9 年12 月10 日      2009   [Refereed]
Physical and functional interaction of transmembrane thioredoxin-related protein (TMX)with MHC class l heavy chain.
松尾禎之,増谷弘,淀井淳司
第82 回日本生化学会 大会 シンポジウム《タンパク質品質管理とレドックス制御》、神戸、2 0 0 9 年1 0 月22 日      2009   [Refereed]
YODOI JUNJI, SON YASUO, KATO NORIKO, MASUTANI HIROSHI
アレルギー   57(3/4) 272   Apr 2008
YOSHIHARA EIJI, MASAKI SATOSHI, MASUTANI HIROSHI, YODOI JUNJI
癌の臨床   54(2) 77-81   Feb 2008
YOSHIHARA EIJI, FUJIMOTO SHIMPEI, INAGAKI NOBUYA, YODOI JUNJI, MASUTANI HIROSHI
生化学   4T21-10   2008
YOKOTA AKIHO, SHIGEOKA SHIGERU, YODOI JUNJI, ASHIDA HIROKI, TAMOI MASAHIRO, HISAZUMI TAKAAKI, FUKUDA HIROKAZU, KATO NORIKO, SOON LIM, INAI KOJI, MASUTANI HIROSHI, AKASHI KIN'YA
バイオテクノロジーシンポジウム予稿集   25th 117-118   Nov 2007
MASUTANI HIROSHI, YODOI JUNJI
衛生薬学・環境トキシコロジー講演要旨集   2007 60   Oct 2007
YODOGAWA JUNJI, KATO NORIKO, INOUE YOSHIHARU, MASUTANI HIROSHI
日本栄養・食糧学会大会講演要旨集   61st 25   Apr 2007
MASAKI SATOSHI, MASUTANI HIROSHI, OKUYAMA HIROTERU, YOSHIHARA EIJI, YODOI JUNJI
月刊細胞   39(3) 92-95   Mar 2007
SUZUKI KANA, MATSUO YOSHIYUKI, TAKENAKA MASAHIRO, OKUYAMA HIROAKI, TERATANI AKIE, FURUKAWA SUZUYO, NAKAMURA HAJIME, MASUTANI HIROSHI, YODOI JUNJI
生化学   3P-0183   2007
ONISHI MASAKO, MOCHIZUKI MICHIKA, YODOI JUNJI, MASUTANI HIROSHI
生化学   2P-0691   2007
YOSHIHARA EIJI, OKA SHIN'ICHI, YODOI JUNJI, MASUTANI HIROSHI
生化学   2P-1363   2007
MATSUO YOSHIYUKI, SUZUKI KANA, SON AOI, HORI OSAMU, OGAWA SATOSHI, OKUYAMA HIROAKI, NAKAMURA HAJIME, KONDO SHINAE, MASUTANI HIROSHI, YODOI JUNJI
生化学   3P-0182   2007
Indentification and molecular analysesof a novel thioredoxin (TRX) and antioxidant responsive element (ARE) induces from Perilla frutescens
増谷 弘, 大槻 涼子, 山口佳美, 叶 順江, 國本 祐二, 竹中 弘, 淀井 淳司
第30 回日本分子生物学会年会・第80 回日本生化学学会大会合同学会 横浜, 2007 年12 月      2007   [Refereed]
Thioredoxin Binding Protein-2 (TBP-2) regulates dendritic cells, NK cells, and allergic responses.
SUWA H., YOSIDA T., SON A., NAKAMURA H., OKUYAMA H., MASUTANI H., YODOI J.
第37 回日本免疫学会・学術集会 東京, 2007 年11 月      2007   [Refereed]
MOCHIZUKI MICHIKA, MASUTANI HIROSHI, KWON YON-WONG, ABE AKIKO, YODOI JUNJI
日本癌学会学術総会記事   65th 474   Aug 2006
Redox regulation by thioredoxin and its related protein.
Yodoi J, Mochizuki M, Hara T, Kondo N, Kato N, Son A, Kaimul AM, Oka S, Masutani H.
東アジアシンポジウム, 韓国, June, 2006      2006   [Refereed]
YOSHIDA TOORU, OKA SHIN'ICHI, INOMATA YASUYA, MASUTANI HIROSHI, NAKAMURA HAJIME, YODOI JUNJI
日本分子生物学会年会講演要旨集   28th 521   Nov 2005
MASUTANI HIROSHI, OKA SHIN'ICHI, AHSAN MD. KAIMUL, WANG DONGMEI, YODOI JUNJI
日本分子生物学会年会講演要旨集   28th 68   Nov 2005
MOCHIZUKI MICHIKA, KWON YONG-WONG, MATSUO YOSHIYUKI, YODOI JUNJI, MASUTANI HIROSHI
日本分子生物学会年会講演要旨集   28th 256   Nov 2005
OKA SHIN'ICHI, LIU WENRUI, MAKATANI HIROSHI, HIRATA HIROMI, SHINKAI YOICHI, YAMADA SHUICHI, YOSHIDA TOORU, NAKAMURA HAJIME, YODOI JUNJI
日本分子生物学会年会講演要旨集   28th 59   Nov 2005
MATSUO YOSHIYUKI, MASUTANI HIROSHI, KONDO SHINAE, YODOI JUNJI
日本分子生物学会年会講演要旨集   28th 603   Nov 2005
SON AOI, ISHII YASUYUKI, KONDO NORIHIKO, OKA SHIN'ICHI, YOSHIDA TOORU, NAKAMURA HAJIME, MASUTANI HIROSHI, YODOI JUNJI
日本免疫学会総会・学術集会記録   35 156   Nov 2005
MASUTANI HIROSHI, YODOI JUNJI
医学のあゆみ   4-8   Jul 2005
Regulation of cellular redoxsignaling and growth by thioredoxin and thioredoxin binding protein-2.
Yodoi J, Kondo N, Yoshida T, Nakamura H, Masutani H.
Sixth International Conference of the Society for Free Radical Research-Africa, Tetouan, Morocco, September 26-29, 2005      2005   [Refereed]
Histone H3phosphorylation via p38 MAPK pathway regulates antioxidant responsive elementactivation.
Kim Y-C, Ahsan MK, Yamaguchi Y, Matsuo Y, Yodoi J, Masutani H.
JST-ERATO Yamamoto Environmental Response Project International Symposium: Molecular Mechanism of Environmental Response to Food and Oxygen, Tsukuba, Japan, March 10-12, 2005.      2005   [Refereed]
MATSUO YOSHIYUKI, KONDO SHINAE, OKA SHIN'ICHI, KONDO NORIHIKO, SON AOI, MASUTANI HIROSHI, YODOI JUNJI
日本分子生物学会年会プログラム・講演要旨集   27th 738   Nov 2004
OKA SHIN'ICHI, MASUTANI HIROSHI, LIU W, YODOI JUNJI
日本分子生物学会年会プログラム・講演要旨集   27th 538   Nov 2004
YOSHIDA TOORU, SON A, MATSUO YOSHIYUKI, OKA SHIN'ICHI, KONDO NORIHIKO, MASUTANI HIROSHI, NAKAMURA HAJIME, YODOI JUNJI
日本分子生物学会年会プログラム・講演要旨集   27th 975   Nov 2004
MASUTANI HIROSHI, AHSAN M K, OKA SHIN'ICHI, KWON Y-W, NISHINAKA YUMIKO, YAMAGUCHI YOSHIMI, MAEDA MICHIYUKI, YODOI JUNJI
日本癌学会総会記事   63rd 225   Aug 2004
HARA TOMIJIRO, OKA SHIN'ICHI, FUNASAKA YOKO, ICHIHASHI MASAMITSU, HIRABAYASHI YOKO, INOUE TOORU, MASUTANI HIROSHI, YODOI JUNJI
太陽紫外線防御研究委員会学術報告   14(1) 35-39   Aug 2004
TOYOKUNI NOBUYA, KUMAR D K, AKATSUKA SHIN'YA, SHIRASE TOMOYUKI, MASUTANI HIROSHI, YODOI JUNJI, HIAI HIROSHI
日本病理学会会誌   93(1) 218   May 2004
YODOI JUNJI, HARA TOMIJIRO, OKA SHIN'ICHI, FUNESAKA YOKO, ICHIHASHI MASAMITSU, HIRABAYASHI YOKO, INOUE TOORU, MASUTANI HIROSHI
太陽紫外線防御研究委員会シンポジウム講演要旨集   14th 27   Mar 2004
MASUTANI HIROSHI
環境保全   (18) 48-56   Dec 2003
OKA SHIN'ICHI, MASUTANI HIROSHI, NISHINAKA YUMIKO, AHSAN K, NAKAMURA HAJIME, YODOI JUNJI
日本分子生物学会年会プログラム・講演要旨集   26th 671   Nov 2003
YOSHIDA TOORU, KIM Y-C, MASUTANI HIROSHI, YODOI JUNJI
日本分子生物学会年会プログラム・講演要旨集   26th 647   Nov 2003
TOYOKUNI SHIN'YA, NISHINAKA YUMIKO, MASUTANI HIROSHI, AKATSUKA SHIN'YA, NISHIZAWA NAMIKO, YODOI JUNJI, HIAI HIROSHI
日本癌学会総会記事   62nd 121   Aug 2003
NISHINAKA YUMIKO, MASUTANI HIROSHI, AHSAN K, OKA SHIN'ICHI, MAEDA MICHIYUKI, HIROTA KIICHI, YODOI JUNJI
日本免疫学会総会・学術集会記録   32 193   Oct 2002
MASUTANI HIROSHI, YAMAGUCHI YOSHIMI, KWON Y-W, YODOI JUNJI
日本癌学会総会記事   61st 215   Aug 2002
YODOI ATSUSHI, NISHINAKA YUMIKO, HIROTA KIICHI, MASUYA HIROSHI, NAKAMURA HAJIME
生化学   74(8) 632   Aug 2002
ORII FUMIKA, MASUTANI HIROSHI, KARIYA MASATOSHI, NIKAIDO TOSHIO, KATO KIYOSHI, SHIMA HIROAKI, KONISHI IKUO, YODOI JUNJI, FUJII SHINGO
日本産科婦人科学会雑誌   54(2) 347(S.261)   Feb 2002
MASUTANI HIROSHI, AHSAN K, NISHINAKA YUMIKO, YAMAGUCHI YOSHIMI, MAEDA MICHIYUKI, YODOI JUNJI
日本免疫学会総会・学術集会記録   31 114   Oct 2001
TANAKA TOORU, HOSOI FUMIHITO, IWAI(YAMAGUCHI) YUKO, MASUTANI HIROSHI, NAKAMURA HAJIME, TAKEDA SHUN'ICHI, YODOI JUNJI
日本癌学会総会記事   60th 141   Sep 2001
KWON Y-W, YODOI JUNJI, MASUTANI HIROSHI
日本癌学会総会記事   60th 144   Sep 2001
ORII AYAKA, KATO KIYOSHI, NIKAIDO TOSHIO, KONISHI IKUO, MASUTANI HIROSHI, YODOI JUNJI, SHIME HIROAKI, KOSAKA CHIKA, FUJII SHINGO
日本癌学会総会記事   60th 368   Sep 2001
NISHINAKA YUMIKO, MASUYA HIROSHI, AHSAN K M, NIKI ETSUO, YODOI JUNJI
生化学   73(8) 941   Aug 2001
KASUNO KENJI, MASUTANI HIROSHI, NAKAMURA HAJIME, MUSO ERI, ONO TAKAHIKO, SHINOYAMA SHIGETAKE, YODOI JUNJI
生化学   73(8) 930   Aug 2001
KEN YOGEN, MASUTANI HIROSHI, YODOI JUNJI
生化学   73(8) 978   Aug 2001
MASUTANI HIROSHI, KWON Y-W, KIM Y-C, YAMAGUCHI YOSHIMI, YODOI JUNJI
日本トキシコロジー学会学術年会要旨集   28th 72   Jun 2001
TANITO MASAKI, NAKAMURA HAJIME, MASUTANI HIROSHI, YODOI JUNJI
臨床検査   45(3) 255-263   Mar 2001
YODOI ATSUSHI, MASUTANI HIROSHI, NAKAMURA HAJIME
日本薬学会年会要旨集   121st(1) 130   Mar 2001
TANITO MASAKI, HAKU KIYOSHI, NAKAMURA HAJIME, MASUTANI HIROSHI, DEGITANI HIROSHI, HIROTA KIICHI, YODOI ATSUSHI
日本免疫学会総会・学術集会記録   30 146   Sep 2000
KASUYA KENJI, MUSO ERI, MASUTANI HIROSHI, NAKAMURA HAJIME, MATSUMORI AKIRA, SHINOYAMA SHIGETAKE, YODOI JUNJI
日本免疫学会総会・学術集会記録   30 64   Sep 2000
NISHINAKA YUMIKO, NISHIYAMA AKIRA, MASUTANI HIROSHI, MAEDA MICHIYUKI, NAKAMURA HAJIME, TATSUMI EIJI, YODOI JUNJI
日本免疫学会総会・学術集会記録   30 63   Sep 2000
NISHIYAMA AKIRA, MASUTANI HIROSHI, MAEDA MICHIYUKI, NISHINAKA YUMIKO, HOSOI FUMIHITO, YODOI JUNJI
Jpn J Cancer Res   91(Supplement (Sept)) 287   Sep 2000
MASUYA HIROSHI, KIM Y-C, KWON Y-W, NISHIYAMA AKIRA, NISHINAKA YUMIKO, NAKAMURA HAJIME, YODOI JUNJI
生化学   72(8) 701   Aug 2000
SONO KENJI, MUSO ERI, ONO TAKAHIKO, MASUTANI HIROSHI, NAKAMURA HAJIME, SHINOYAMA SHIGENORI, YODOI JUNJI
日本腎臓学会誌   42(3) 162   Apr 2000
KASUNO KENJI, MUKAI ERI, MASUYA HIROSHI, NAKAMURA HAJIME, SHINOYAMA SHIGETAKE, YODOI JUNJI
日本免疫学会総会・学術集会記録   29 31   Oct 1999
NISHIYAMA AKIRA, MASUTANI HIROSHI, MATSUMOTO KEN, HIROTA KIICHI, YODOI JUNJI
日本免疫学会総会・学術集会記録   29 308   Oct 1999
MATSUMOTO KEN, NISHIYAMA AKIRA, MASUTANI HIROSHI, NAKAMURA HAJIME, KEN NEIHAKU, HASHIMOTO OSAMU, HORIE TAKASHI, YODOI JUNJI
日本免疫学会総会・学術集会記録   29 314   Oct 1999
MASUTANI HIROSHI, YAMAGUCHI YOSHIMI, KIM Y-C, KWON Y-W, TANITO MASAKI, UEDA SHUGO, YODOI JUNJI
日本免疫学会総会・学術集会記録   29 314   Oct 1999
UEDA SHUGO, NAKAMURA HAJIME, MASUTANI HIROSHI, TAKABAYASHI ARIMICHI, YAMAOKA YOSHIO, YODOI JUNJI
日本癌学会総会記事   58th 169   Aug 1999
UENO MASAYA, MASUTANI HIROSHI, ARAI JUN, YAMAUCHI KIYOAKI, NIKAIDO TOSHIO, INAMOTO TAKASHI, YAMAOKA YOSHIO, YODOI JUNJI
日本癌学会総会記事   58th 525   Aug 1999
MASUTANI HIROSHI, NAKAMURA HAJIME, YODOI JUNJI
医学のあゆみ   174-178   May 1999
NISHIYAMA AKIRA, MASUTANI HIROSHI, HIROTA YOSHIKAZU, YODOI ATSUSHI
日本免疫学会総会・学術集会記録   28 184   Oct 1998
UEDA SHUGO, NAKAMURA HAJIME, MASUTANI HIROSHI, YONEHARA SHIN, TAKABAYASHI ARIMICHI, YAMAOKA YOSHIO, YODOI JUNJI
日本免疫学会総会・学術集会記録   28 296   Oct 1998
MASUTANI HIROSHI, YAMAGUCHI YOSHIMI, KWON Y-W, YODOI JUNJI
日本免疫学会総会・学術集会記録   28 318   Oct 1998
SONO HIROSHI, MASUTANI HIROSHI, YODOI JUNJI
からだの科学   (198) 73-78   Jan 1998

Books etc

 
Molecular Interventions in Lifestyle-Related Diseases
Masutani H, Nishinaka Y, Kim YC, Yodoi J. (Part:Joint Work, The Gene Regulatory Mechanism of Thioredoxin and Thioredoxin Binding Protein-2/VDUP1 in Cancer Prevention.)
Taylor & Francis   2006   
Environmental Stressors in Health and Disease
Masutani H, Nishiyama A, Kwon YW, Nakamura H, Yodoi J.
Marcel Dekker   2001   
Antioxidant and Redox Regulation of Genes.
Masutani H, Ueno M, Ueda S, Yodoi J.
Academic Press   2000   
ADF(adult T cell derived factor)/human thioredoxin and viral intection : possible new therapentic approach.
Microbial Infections Role of Biological Response Modifiers. edited by Herrman Fridman. Prennm press   1992   
Role of thioredoxin family in the redox regulation of oxidative stress response and signalling. In ″Antioxidant and Redox regulation of genes. ″edited by Chandan K. Sen, Helmut Sies and Patrick A. Baeuerle (jointly authored)
Baeurele, Academic press   2000   

Conference Activities & Talks

 
Thioredoxin interacting protein (Txnip) forms high molecular weight ribonucleoprotein complexes in cancer cells
Hirata Cristiane L, NIshioka K, Ashida S, Mizutani Y, Iwai-Kanai E, Inamoto T, Masutani H
THe 27th Annual Meeting of the Japanese Society for Cell Death Research   27 Jul 2018   
Development of drugs against anti-diabetes and recognition disorders based on Txnip
17 May 2018   
Thioredoxin interacting protein (Txnip) High order complex formation in cancer cells
Cristiane Lumi Hirata, Kanari Nishioka, Sae Ashida, Yoichi Mizutani, Shinji Ito,Hiroshi Masutani
28 Sep 2017   
Development of redox modulating approaches against cancer and diabetes by Thioredoxin binding protein-2 (TBP-2) /Txnip [Invited]
Masutani, H and Hirata, CL
17th Biennial Meeting of Society for Free Radical Research International   2014   
Thioredoxin binding protein-2 (TBP-2)/ Txnip/ VDUP1 with multifunctional biostress signal regulatory activities [Invited]
MASUTANI Hiroshi
2012   
Thioredoxin binding protein-2 is a key regulator of mitochondrial energy production and membrane potential.
Yoshihara E, Fujimoto S, Inagaki N, Yodoi J, Masutani H
Keystone symposia, Cell death pathways   2009   
Thioredoxin and thioredoxin binding protein-2 (TBP-2) Txnip in oncology and metabolism. [Invited]
MASUTANI Hiroshi
SFRR international Free Radical School in Japan   2009   
Redox regulation of inflammation and metabolic stress by TRX/ TBP-2 system [Invited]
odoi, J., Son, A., Mitsui, A., Oka., S., Liu, W., Kato, N., Yoshida, T., Okuyama, H., and Masutani H
SFRR Europa 2007 Meeting   2007   
Thioredoxin inducers: Molecular mechanism and Application [Invited]
MASUTANI Hiroshi
2nd Verona Meeting Phytotherapy Food & Health   2007   
Redox control of cell growth and metabolism by thioredoxin and thioredoxin-binding protein-2 (TBP-2)/ VDUP1/ Txnip [Invited]
Masutani H, Mochizuki M, Oka S, Yoshihara E, Onishi M, Yodoi J
The 4th Meeting of International Redox Network   2007   

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2001 - 2002    Investigator(s): Hiroshi MASUTANI
AIM: We investigated the function of thioredoxin (TRX) by analyzing activation mechanism of the thioredoxin gene.RESULTS: 1) We demonstrated that the TRX gene is induced by hemin or tertial butylhydroquinone (tBHQ) through antioxidant responsive e...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2005 - 2006    Investigator(s): 近藤 則彦, Junji YODOI
Thioredoxi-1 (TRX) plays important roles on cellular signaling by controlling the redox state of cysteines residues in target proteins. TRX is released in response to oxidative stress and shows various biological functions also in extracellular en...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 1998 - 1999    Investigator(s): Hiroshi MASUTANI
To investigate the molecular mechanism of oxidative stress related pathological conditions such as inflammation, reperfusion injury, carcinogenesis, and allergy, we have studied the mechanism of oxidative stress signaling and response.We have obta...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2004 - 2005    Investigator(s): Shugo UEDA
Human thioredoxin is a multifunctional redox-active protein. We investigated the effect of recombinant human thioredoxin (rhTRX) on tumor growth and chemosensitivity. rhTRX did not affect the tumor growth of human colon carcinoma cell lines, HT-29...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(A))
Project Year: 2003 - 2005    Investigator(s): Junji YODOI
<TBP-2 knockout (KO) mice>TRX binding protein 2 (TBP-2) binds to reduced TRX but not to oxidized TRX, and is a negative regulator of TRX. We analyzed the function of TBP-2 by means of molecular, cellular approach, and genetically modified mice. TB...