1997年1月
Asymmetric cycloaddition of anthrone with N-substituted maleimides with C-2-chiral pyrrolidines
TETRAHEDRON-ASYMMETRY
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- ,
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- 巻
- 8
- 号
- 1
- 開始ページ
- 101
- 終了ページ
- 107
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/S0957-4166(96)00473-9
- 出版者・発行元
- PERGAMON-ELSEVIER SCIENCE LTD
Base-catalyzed asymmetric cycloaddition of anthrone with achiral and chiral N-substituted maleimides was carried out in the presence of C-2-chiral pyrrolidines in almost quantitative yields. Chiral, non-racemic [4+2] adducts up to 61% ee were produced with achiral N-methyl and N-benzylmaleimide using the chiral catalysts. De's of the adducts up to 38% were observed in the cases of chiral N-substituted maleimides and achiral pyrrolidine, in which the absolute configuration of the major product was established by X-ray analysis. The combination of chiral maleimides and chiral catalysts afforded the adducts having up to 80% de. (C) 1997 Published by Elsevier Science Ltd. All rights reserved.
- リンク情報
- ID情報
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- DOI : 10.1016/S0957-4166(96)00473-9
- ISSN : 0957-4166
- Web of Science ID : WOS:A1997WD63200019