2021年9月1日
Intramolecular Addition of a Dimethylamino C(sp 3)-H Bond across C-C Triple Bonds Using IrCl(DTBM-SEGPHOS)(ethylene) Catalyst: Synthesis of Indoles from 2-Alkynyl- N -methylanilines
Synthesis (Germany)
- ,
- ,
- ,
- 巻
- 53
- 号
- 17
- 開始ページ
- 3057
- 終了ページ
- 3064
- 記述言語
- 掲載種別
- 研究論文（学術雑誌）
- DOI
- 10.1055/a-1511-1025
Intramolecular addition of a C(sp 3)-H bond of the dimethylamino group across the C-C triple bond in 2-alkynyl- N, N -dimethylanilines is effectively catalyzed by a new iridium complex, IrCl(DTBM-SEGPHOS)(C 2H 4), in mesitylene at 150 °C. The intramolecular C(sp 3)-H addition is followed by double-bond isomerization to afford 3-substituted indoles in good to high yields.
- リンク情報
- ID情報
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- DOI : 10.1055/a-1511-1025
- ISSN : 0039-7881
- eISSN : 1437-210X
- SCOPUS ID : 85108565258