2021年5月11日
Copper-catalyzed regioselective: Trans -silaboration of internal arylalkynes with stereochemical switch to cis -addition mode
Chemical Communications
- ,
- ,
- 巻
- 57
- 号
- 38
- 開始ページ
- 4670
- 終了ページ
- 4673
- 記述言語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1039/d1cc01579f
Copper-catalyzed silafunctionalization of alkynes using a silylboronic ester as a silicon source has recently progressed rapidly. Generally, the reaction affords a product with cis-stereoselectivity. We herein describe trans-selective 1,2-addition of silylboronic esters to internal arylalkynes, which was promoted efficiently by the CuOt-Bu/RCy2P/NaOt-Bu catalysts. Moreover, we report a stereochemical switch to cis-addition in the reactions of Me2(i-PrO)Si-B(pin) in hydrocarbon solvents including cyclohexane.
- リンク情報
- ID情報
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- DOI : 10.1039/d1cc01579f
- ISSN : 1359-7345
- eISSN : 1364-548X
- PubMed ID : 33978003
- SCOPUS ID : 85105724721