OZAKI Keiichi

J-GLOBAL         Last updated: May 28, 2019 at 08:17
OZAKI Keiichi
Osaka University of Pharmaceutical Sciences
Faculty of Pharmaceutical Sciences
Job title
Associate Professor
Doctor (Pharmaceutical Sciences)(Kyoto University), Master (Pharmaceutical Sciences)(Kyoto University)

Research Areas


Academic & Professional Experience

 Associate Professor,Graduate School of Biomedical Science,Graduate School of Biomedical Sciences,Nagasaki University
 Associate Professor,Pharmaceutical Sciences,Pharmaceutical Sciences,Graduate School of Biomedical Sciences,Nagasaki University
 Research Associate
 Visiting Researcher,Johns Hopkins University

Published Papers

Effect of cationic lipid type in cationic liposomes for siRNA delivery into the liver by sequential injection of chondroitin sulfate and cationic lipoplex.
Hattori Y, Takeuchi N, Nakamura M, Yoshiki Y, Taguchi M, Ohno H, Ozaki K, Onishi H
J. Drug Deliv. Sci. Tec.   48 235-244   2018   [Refereed]
Establishment of novel reporter cells stably maintaining transcription factor-driven human secreted alkaline phosphatase expression.
Kurata R, Kumagai A, Cui X, Harada M, Nagai J, Yoshida Y, Ozaki KI, Tanaka Y, Yonezawa T.
Curr Pharm Biotechnol.   19 224-231   2018   [Refereed]


Yoshiyuki Hattori, Mari Nakamura, Nozomi Takeuchi, Kyoko Tamaki, Satono Shimizu, Yuki Yoshiike, Masamitsu Taguchi, Hiroaki Ohno, Kei Ichi Ozaki, Hiraku Onishi
Journal of Drug Targeting      Jan 2018
© 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group. Cationic liposomes composed of dialkyl cationic lipid such as 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) can efficiently deliver siRNA to the lungs following the intrave...
Yoshiyuki Hattori, Takuto Kikuchi, Mari Nakamura, Kei Ichi Ozaki, Hiraku Onishi
Oncology Letters   14 5157-5166   Nov 2017
© 2017, Spandidos Publications. All rights reserved. It has been reported that suppression of protein kinase N3 (PKN3) expression in vascular and lymphatic endothelial cells results in the inhibition of tumor progression and lymph node metastasis ...
Yoshiyuki Hattori, Takuto Kikuchi, Kei Ichi Ozaki, Hiraku Onishi
Experimental and Therapeutic Medicine   14 4300-4306   Nov 2017
© 2017, Spandidos Publications. All rights reserved. Mitotic progression is regulated by the phos­phorylation of heat shock transcription factor 1 (HSF1) by polo‑like kinase 1 (PLK1); however, this interaction is often deregulated in tumors. High ...
Yoshiyuki Hattori, Ayako Nakamura, Shiori Hanaya, Yuta Miyanabe, Yuki Yoshiike, Takuto Kikuchi, Kei ichi Ozaki, Hiraku Onishi
Journal of Drug Delivery Science and Technology   41 401-409   Oct 2017
© 2017 Elsevier B.V. Previously, we found that intravenous injection of chondroitin sulfate (CS), followed by intravenous injection of siRNA/cationic liposome complexes (siRNA lipoplexes) could deliver siRNAs to the liver and suppress expression o...
Mana Furuoka, Kei Ichi Ozaki, Daichi Sadatomi, Sayaka Mamiya, Tomo Yonezawa, Susumu Tanimura, Kohsuke Takeda
Journal of Cellular Physiology   231 2761-2767   Dec 2016
© 2016 Wiley Periodicals, Inc. The intracellular cysteine protease caspase-1 is critically involved in obesity-induced inflammation in adipose tissue. A substantial body of evidence from immune cells, such as macrophages, has shown that caspase-1 ...


Study on the structure and function of macrophage lectins
Study on the physiological furction of insulin receptor-related receptor
Functional analysis of Sprouty isoforms in the uterine artery endothelial Cells

Research Grants & Projects

Epigenetics in tumor cells
Project Year: 1999   
Molecular Biological study on Peptide hormone & Growth Factor
Project Year: 1999   
Molecular Biological study on the Regulation of Cell Growth
Grant-in-Aid for Scientific Research
Project Year: 1999