Hiroshi Yamaguchi - My portal

Profile Information

Affiliation: Professor, School of Science and Technology, Department of Chemistry, Kwansei Gakuin University

Degree: Dr. of Science(Osaka University)

J-GLOBAL ID: 200901065174428606
researchmap Member ID: 1000163190

Research Interests

Research Areas

Research History

Oct, 2008 - Present

School of Science and Technology, Kwansei Gakuin University
Oct, 2002 - Sep, 2008

School of Science and Technology, Kwansei Gakuin University
Apr, 1997 - Oct, 2002

Kwansei Gakuin University
Oct, 1992 - Mar, 1997

Institute for Protein Research, Osaka University

Papers

Inhibitory effects of local anesthetics on the proteasome and their biological actions.

U. Bahrudin, M. Unno, K. Nishio, A. Kita, P. Li, M. Kato, M. Inoue, S. Tsujitani, T. Murakami, R. Sugiyama …

Scientific Reports., 7 5079, 2017 Peer-reviewed
Probing the Catalytic Mechanism of Copper Amine Oxidase from Arthrobacter globiformis with Halide Ions

Takeshi Murakawa, Akio Hamaguchi, Shota Nakanishi, Misumi Kataoka, Tadashi Nakai, Yoshiaki Kawano, Hiroshi Yamaguchi, Hideyuki Hayashi, Katsuyuki Tanizawa, Toshihide Okajima

JOURNAL OF BIOLOGICAL CHEMISTRY, 290(38) 23094-23109, Sep, 2015 Peer-reviewed
Inhibition of the Functional Interplay between Endoplasmic Reticulum (ER) Oxidoreduclin-1 alpha (Ero1 alpha) and Protein-disulfide Isomerase (PDI) by the Endocrine Disruptor Bisphenol A

Masaki Okumura, Hiroshi Kadokura, Shoko Hashimoto, Katsuhide Yutani, Shingo Kanemura, Takaaki Hikima, Yuji Hidaka, Len Ito, Kohei Shiba, Shoji Masui …

JOURNAL OF BIOLOGICAL CHEMISTRY, 289(39) 27004-27018, Sep, 2014 Peer-reviewed
Radically Different Thioredoxin Domain Arrangement of ERp46, an Efficient Disulfide Bond Introducer of the Mammalian PDI Family

Rieko Kojima, Masaki Okumura, Shoji Masui, Shingo Kanemura, Michio Inoue, Masatoshi Saiki, Hiroshi Yamaguchi, Takaaki Hikima, Mamoru Suzuki, Shuji Akiyama …

STRUCTURE, 22(3) 431-443, Mar, 2014 Peer-reviewed
Weak interaction of an inhibitor in the 20S proteasome.

T. Murakami, H. Yamaguchi, U. Bahrudin, A. Kita, I. Hisatome, Y. Saeki, K. Tanaka, M. Unno, Y. Morimoto

Acta Crystarogr., A70 C487, 2014 Peer-reviewed
Glutathione Ethylester, a Novel Protein Refolding Reagent, Enhances both the Efficiency of Refolding and Correct Disulfide Formation

Len Ito, Masaki Okumura, Kohsaku Tao, Yusuke Kasai, Shunsuke Tomita, Akiko Oosuka, Hidetoshi Yamada, Tomohisa Shibano, Kentaro Shiraki, Takashi Kumasaka …

PROTEIN JOURNAL, 31(6) 499-503, Aug, 2012 Peer-reviewed
Crystallization and preliminary crystallographic analysis of the complex between triiodothyronine and the bb ' fragment of rat protein disulfide isomerase

Shoko Hashimoto, Len Ito, Masaki Okumura, Tomohisa Shibano, Marina Nawata, Takashi Kumasaka, Hiroshi Yamaguchi, Susumu Imaoka

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS, 68 476-478, Apr, 2012 Peer-reviewed
Effect of Surface Defects on Auger Recombination in Colloidal CdS Quantum Dots

Yoichi Kobayashi, Takatoshi Nishimura, Hiroshi Yamaguchi, Naoto Tamai

JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 2(9) 1051-1055, May, 2011 Peer-reviewed
Acceleration of disulfide-coupled protein folding using glutathione derivatives

Masaki Okumura, Masatoshi Saiki, Hiroshi Yamaguchi, Yuji Hidaka

FEBS JOURNAL, 278(7) 1137-1144, Apr, 2011 Peer-reviewed
High-resolution X-ray analysis reveals binding of arginine to aromatic residues of lysozyme surface: implication of suppression of protein aggregation by arginine

Len Ito, Kentaro Shiraki, Takanori Matsuura, Masaki Okumura, Kazuya Hasegawa, Seiki Baba, Hiroshi Yamaguchi, Takashi Kumasaka

PROTEIN ENGINEERING DESIGN & SELECTION, 24(3) 269-274, Mar, 2011 Peer-reviewed
Detection of the reaction intermediates catalyzed by a copper amine oxidase

Misumi Kataoka, Hiroko Oya, Ayuko Tominaga, Masayuki Otsu, Toshihide Okajima, Katsuyuki Tanizawa, Hiroshi Yamaguchi

JOURNAL OF SYNCHROTRON RADIATION, 18 58-61, Jan, 2011 Peer-reviewed
Fiber Formation of a Synthetic Spider Peptide Derived From Nephila clavata

Yuji Hidaka, Ko-Ichi Kontani, Rina Taniguchi, Masatoshi Saiki, Sayoko Yokoi, Kenji Yukuhiro, Hiroshi Yamaguchi, Mitsuhiro Miyazawa

BIOPOLYMERS, 96(2) 222-227, 2011 Peer-reviewed
Oxidative Folding of Prouroguanylin

Y. Yamazaki, M. Okumura, L. Ito, T. Maekawa, A. Matsuoka, Y. Yoshida, H. Yamaguchi, Y. Hidaka

Peptide Science 2010, 47 164, 2011 Peer-reviewed
Role of Leu66 in the Folding of Uroguanylin Assisted by the Pro-peptide Region

YAMAGUCHI Hiroshi

Peptide Science 2010, 47 163, 2011 Peer-reviewed
Heparin-Induced Conformational Change in the Extra-cellular Domain of the Precursor Protein of β-Amyloid

A. Matsuoka, M. Okumura, L. Ito, Y. Yamazaki, H. Yamaguchi, M. Niinobe, Y. Hidaka

Peptide Science 2010, 47 162, 2011 Peer-reviewed
A Novel Reagent for Disulfide-Coupled Protein Folding

M. Okumura, M. Saiki, H. Yamaguchi, Y. Hidaka

Peptide Science 2010, 47 170, 2011 Peer-reviewed
Crystallization and preliminary crystallographic analysis of Achromobacter protease I mutants

Len Ito, Kentaro Shiraki, Tatsuya Uchida, Masaki Okumura, Hiroshi Yamaguchi

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS, 66 1531-1532, Nov, 2010 Peer-reviewed
Comparative analysis of amino acids and amino-acid derivatives in protein crystallization

Len Ito, Kentaro Shiraki, Hiroshi Yamaguchi

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 66 744-749, Jun, 2010 Peer-reviewed
Amino acids and glycine ethyl ester as new crystallization reagents for lysozyme

Len Ito, Kentaro Shiraki, Hiroshi Yamaguchi

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 66 750-754, Jun, 2010 Peer-reviewed
Expression, Purification, and Crystallization of Proopiomelanocortin

K. Watanabe, Y. Hosokawa, L. Ito, A. Basak, H. Yamaguchi, Y. Hidaka

Pept.Sci.2008, 45 469-472, 2009 Peer-reviewed

Misc.

Time-Series Structural Studies of Topaquinone Biogenesis in Copper Containing Amine Oxidase

YAMAGUCHI Hiroshi, KIM Misa

X-RAYS, 45, 262-267(4) 262-267, 2003
Role of copper ion in bacterial copper amine oxidase: Spectroscopic and crystallographic studies of metal-substituted enzymes

S Kishishita, T Okajima, M Kim, H Yamaguchi, S Hirota, S Suzuki, S Kuroda, K Tanizawa, M Mure

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 125(4) 1041-1055, Jan, 2003
X-ray snapshots of quinone cofactor biogenesis in bacterial copper amine oxidase

M Kim, T Okajima, S Kishishita, M Yoshimura, A Kawamori, K Tanizawa, H Yamaguchi

NATURE STRUCTURAL BIOLOGY, 9(8) 591-596, Aug, 2002
銅含有アミン酸化酵素のトパキノン補酵素生成過程の研究

構造生物, 8, 10-21, 2002
X-ray structure of azide-bound fully oxidized cytochrome c oxidase from bovine heart at 2.9Å resolution.(jointly worked)

Acta Crystallgraphica, D56 529-535, 2000
Structure analysis of bovine heart cytochrome C oxidase at 2.8Å resolution

Acta Crystallographica, D55(1) 31, 1999
CRYSTALLIZATION AND FURTHER CHARACTERIZATION OF META-HYDROXYBENZOATE 4-HYOROXYLASE FROM ┣DBMAUC COMAMONAS TESTOSTERONI(/)┫DB

Research Communications in Biochemistry, Cell and Molecular Biology, 2(3&4) 253, 1998
Redox-Coupled Crystal Structural Changes in Bovine Heart Cytochrome C Oxidase(jointly worked)

Science, 280(5370) 1723-1729, 1998
Crystal Structures of the copper-containing amine oxidase from Arthrobacter globiformis in the holo- and apo- forms : Implications for the biogenesis of topa quinone(jointly worked)

Biochemistry, 36(51) 16116-16133, 1997
The Whole Structure of the 13-Subunit Oxidized Cytochrome c Oxidase at 2.8(]J1009[)(jointly worked)

Science, 272(5265) 1136-1144, 1996
Structures of Metal Sites of Oxidiqed Bovine Heart Cytochrome c Oxidase at 2.8A

Science, 269(5227) 1069-1074, 1995
Flexible loop that is novel catalitic machinery in a ligase Atomic structure and function of the loopless glutathione Synthetase(jointly worked)

Biochemistry, 33(17) 4995-4999, 1994
グルタチオン合成酵素の構造と機能の解析(共著)

蛋白質核酸酵素, 38(10) 1579, 1993
Structural and Functional Analysis on Glutathione Synthetase

Protein, Nucleic Acid and Enzyme, 38(10) 1579, 1993
Flexibility Impaired by Mutations Revealed the Multifunctional Roles of the Loop in Glutathione Synthetase(jointly worked)

Biochemistry, 32(46) 12398-12404, 1993
Use of Adenosine(5')-polyphospho(5')pyridoxals To Study the Substrate-Binding Region of Glutathione Synthetase from ┣DBEscherichia(/)-┫DB ┣DBcoli(/)-┫DB B(jointly worked)

Biochemistry, 32(6) 1548-1554, 1993
Three-dimensional Structure of the Glutathione Synthetase from ┣DBEscherichia(/)-┫DB ┣DBcoli(/)-┫DB B at 2.0Å Resolution(jointly worked)

Journal of Molecular Biology, 229(4) 1083, 1993
シトクロムC酸化酵素の立体構造を見る「(共著)」

蛋白質・核酸・酵素別刷見る技術, 42(別刷7) 977
Three dimensional structure of the cytochrome C oxidase(jointly worked)

Protein, Nucleic Acid and Enzyme, Suppliment 7., 42(Sup.7) 977

Professional Memberships

Works

Research Projects

初期発生関連タンパク質の構造生物学

大型放射光施設利用研究推進, 1998
m-ヒドロキシ安息香酸-4-水酸化酵素の結晶構造解析

1996
フェニルエチルアミン酸化酵素の構造学的研究

科学研究費補助金, 1995
Structure Determination of m-hydroxybenzoate -4-hydroxylase
Structural Studies on Phenylethylamine Oxidase
Structural Studies on Adenylate kinase