藤永由佳子 (Yukako Fujinaga) - マイポータル

基本情報

所属: 金沢大学医薬保健研究域医学系教授

学位: 博士(医学)
薬学修士

J-GLOBAL ID: 200901041738242005
researchmap会員ID: 1000163594

研究キーワード

研究分野

経歴

2011年 - 2015年

大阪大学微生物病研究所附属感染症国際センター特任教授（常勤）
2005年 - 2011年

大阪大学微生物病研究所附属感染症国際研究センター特任准教授（常勤）
1992年

- Department of Bacteriology Okayama University Medical School : Research Associate

論文

Molecular engineering of a minimal E-cadherin inhibitor protein derived from Clostridium botulinum hemagglutinin.

Sho Amatsu, Takuhiro Matsumura, Masahiko Zuka, Yukako Fujinaga

The Journal of biological chemistry 299(3) 102944-102944 2023年1月24日
Patient-derived Enterococcus faecium with inflammatory genotypes promote colitis

Ziyu Wang, Noriho Iida, Jun Seishima, Hirofumi Okafuji, Masahiro Yutani, Yukako Fujinaga, Yusuke Hashimoto, Haruyoshi Tomita, Eishiro Mizukoshi, Shuichi Kaneko

Journal of Gastroenterology 2022年7月26日
Oral Corticosteroids Impair Mucin Production and Alter the Posttransplantation Microbiota in the Gut.

Hirofumi Okafuji, Noriho Iida, Kazuya Kitamura, Jun Seishima, Ziyu Wang, Masahiro Yutani, Takatoshi Yoshio, Taro Yamashita, Yoshio Sakai, Masao Honda, Tatsuya Yamashita, Yukako Fujinaga, Reiko Shinkura, Yasuhito Hamaguchi, Eishiro Mizukoshi, Shuichi Kaneko

Digestion 1-18 2022年2月18日
Membrane Vesicles Derived From Clostridium botulinum and Related Clostridial Species Induce Innate Immune Responses via MyD88/TRIF Signaling in vitro

Nobuhide Kobayashi, Kimihiro Abe, Sachiyo Akagi, Mayu Kitamura, Yoshitake Shiraishi, Aki Yamaguchi, Masahiro Yutani, Sho Amatsu, Takuhiro Matsumura, Nobuhiko Nomura, Noriyuki Ozaki, Nozomu Obana, Yukako Fujinaga

Frontiers in Microbiology 13 2022年2月3日
Chronic liver disease enables gut Enterococcus faecalis colonization to promote liver carcinogenesis.

Noriho Iida, Eishiro Mizukoshi, Tatsuya Yamashita, Masahiro Yutani, Jun Seishima, Ziyu Wang, Kuniaki Arai, Hikari Okada, Taro Yamashita, Yoshio Sakai, Yusuke Masuo, Rina Agustina, Yukio Kato, Yukako Fujinaga, Masanobu Oshima, Masao Honda, François Lebreton, Michael S Gilmore, Shuichi Kaneko

Nature cancer 2(10) 1039-1054 2021年10月
Effects of antibiotics on the viability of and toxin production by Clostridium botulinum.

Masahiro Yutani, Takuhiro Matsumura, Yukako Fujinaga

Microbiology and immunology 65(10) 432-437 2021年7月5日査読有り
Fully Human Monoclonal Antibodies Effectively Neutralizing Botulinum Neurotoxin Serotype B.

Takuhiro Matsumura, Sho Amatsu, Ryo Misaki, Masahiro Yutani, Anariwa Du, Tomoko Kohda, Kazuhito Fujiyama, Kazuyoshi Ikuta, Yukako Fujinaga

Toxins 12(5) 2020年5月7日査読有り
Botulinum Hemagglutinin: Critical Protein for Adhesion and Absorption of Neurotoxin Complex in Host Intestine.

Sho Amatsu, Yukako Fujinaga

Methods in molecular biology (Clifton, N.J.) 2132 183-190 2020年査読有り
Functional Analysis of Botulinum Hemagglutinin (HA).

Takuhiro Matsumura, Yukako Fujinaga

Methods in molecular biology (Clifton, N.J.) 2132 191-200 2020年査読有り
Gut-derived Enterococcus faecium from ulcerative colitis patients promotes colitis in a genetically susceptible mouse host.

Jun Seishima, Noriho Iida, Kazuya Kitamura, Masahiro Yutani, Ziyu Wang, Akihiro Seki, Taro Yamashita, Yoshio Sakai, Masao Honda, Tatsuya Yamashita, Takashi Kagaya, Yukihiro Shirota, Yukako Fujinaga, Eishiro Mizukoshi, Shuichi Kaneko

Genome biology 20(1) 252-252 2019年11月25日査読有り
Collagen adhesion gene is associated with blood stream infections caused by methicillin-resistant Staphylococcus aureus.

Iwata Y, Satou K, Furuichi K, Yoneda I, Matsumura T, Yutani M, Fujinaga Y, Hase A, Morita H, Ohta T, Senda Y, Sakai-Takemori Y, Wada T, Fujita S, Miyake T, Yasuda H, Sakai N, Kitajima S, Toyama T, Shinozaki Y, Sagara A, Miyagawa T, Hara A, Shimizu M, Kamikawa Y, Ikeo K, Shichino S, Ueha S, Nakajima T, Matsushima K, Kaneko S, Wada T

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 91 22-31 2019年11月査読有り
Maintenance of an undifferentiated state of human-induced pluripotent stem cells through botulinum hemagglutinin-mediated regulation of cell behavior

Eri Shuzui, MeeHae Kim, Keisuke Azuma, Yukako Fujinaga, Masahiro Kino-oka

Journal of bioscience and bioengineering 127(6) 744-751 2019年6月査読有り
Translocation and dissemination of botulinum neurotoxin from the intestinal tract

Yukako Fujinaga, Michel R. Popoff

Toxicon 147 13-18 2018年6月1日査読有り
Toxins 2017 conference in Madrid

Alberto Albanese, Francisco Cardoso, Yukako Fujinaga, Joseph Jankovic, Andreas Rummel, Giampietro Schiavo

Toxicon 147 1-1 2018年6月1日査読有り
A Simple and Robust Method for Culturing Human-Induced Pluripotent Stem Cells in an Undifferentiated State Using Botulinum Hemagglutinin

Mee-Hae Kim, Yoshifumi Matsubara, Yukako Fujinaga, Masahiro Kino-oka

Biotechnology Journal 13(2) 2018年2月1日査読有り
Multivalency effects of hemagglutinin component of type B botulinum neurotoxin complex on epithelial barrier disruption

Sho Amatsu, Takuhiro Matsumura, Masahiro Yutani, Yukako Fujinaga

Microbiology and Immunology 62(2) 80-89 2018年2月1日査読有り
A Simple and Robust Method for Culturing Human-Induced Pluripotent Stem Cells in an Undifferentiated State Using Botulinum Hemagglutinin

Mee-Hae Kim, Yoshifumi Matsubara, Yukako Fujinaga, Masahiro Kino-oka

Biotechnology Jounal 13(2) 1700384 (1)-1700384(10) 2018年2月査読有り
Botulinum hemagglutinin-mediated selective removal of cells deviating from the undifferentiated state in hiPSC colonies

Mee-Hae Kim, Yo Sugawara, Yukako Fujinaga, Masahiro Kino-oka

SCIENTIFIC REPORTS 7(1) 93-93 2017年3月査読有り
Clostridium botulinum type C hemagglutinin affects the morphology and viability of cultured mammalian cells via binding to the ganglioside GM3

Yo Sugawara, Masao Iwamori, Takuhiro Matsumura, Masahiro Yutani, Sho Amatsu, Yukako Fujinaga

FEBS JOURNAL 282(17) 3334-3347 2015年9月査読有り
Botulinum toxin A complex exploits intestinal M cells to enter the host and exert neurotoxicity

Takuhiro Matsumura, Yo Sugawara, Masahiro Yutani, Sho Amatsu, Hideo Yagita, Tomoko Kohda, Shin-Ichi Fukuoka, Yutaka Nakamura, Shinji Fukuda, Koji Hase, Hiroshi Ohno, Yukako Fujinaga

NATURE COMMUNICATIONS 6 6255-6255 2015年2月査読有り