1998年2月
Protective roles of two aluminum (Al)-induced genes, HSP150 and SED1 of Saccharomyces cerevisiae, in Al and oxidative stresses
FEMS MICROBIOLOGY LETTERS
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- ,
- ,
- ,
- 巻
- 159
- 号
- 1
- 開始ページ
- 99
- 終了ページ
- 105
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/S0378-1097(97)00554-5
- 出版者・発行元
- ELSEVIER SCIENCE BV
We isolated two yeast cDNA clones whose transcripts are induced by aluminum (Al) metal stress. Partial nucleotide sequencing showed that one is the HSP150 gene encoding a secreted heat shock protein, and the other corresponds to the SED1 gene encoding a putative membrane protein. To clarify the biological functions of these genes, we analyzed the sensitivity of gene-disrupted mutants to Al stress and to oxidative stresses. The Al tests indicated that the HSP150 protein served a basal protective role in Al stress, but SED1 did nor, both of the genes had protective roles for oxidative stresses. The results for the HSP150 gene suggest that there is an overlap between Al ion stress, oxidative stress and heat shock stress in yeast. (C) 1998 Published by Elsevier Science B.V. All rights reserved.
- リンク情報
- ID情報
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- DOI : 10.1016/S0378-1097(97)00554-5
- ISSN : 0378-1097
- J-Global ID : 200902163524783353
- Web of Science ID : WOS:000071829700015