桑野信彦 (Michihiko Kuwano) - マイポータル - researchmap

基本情報

所属: 九州大学先端融合医療レドックスナビ研究拠点特任教授

学位: M.D., Ph.D(Kyushu University)

J-GLOBAL ID: 200901051012043653
researchmap会員ID: 1000164242

研究キーワード

2

研究分野

1

ライフサイエンス / 病態医化学 /

経歴

4

1978年 - 1993年

大分医科大学
1971年 - 1978年

Research associate, assistant professor and
Kyushu University School of Medicine
associate professor, Cancer Research Institute,

学歴

2

- 1969年

九州大学
- 1964年

九州大学

受賞

2

1978年

日本生化学会奨励賞
1974年

山極-吉田記念国際癌研究奨励賞(UICC)

MISC

70

Trafficking and functional defects by mutations of the ATP-binding domains in MRP2 in patients with Dubin-Johnson syndrome

K Hashimoto, T Uchiumi, T Konno, T Ebihara, T Nakamura, M Wada, S Sakisaka, F Maniwa, T Amachi, K Ueda …

HEPATOLOGY 36(5) 1236-1245 2002年11月
Novel translational control through an iron-responsive element by interaction of multifunctional protein YB-1 and IRP2

M Ashizuka, T Fukuda, T Nakamura, K Shirasuna, K Iwai, H Izumi, K Kohno, M Kuwano, T Uchiumi

MOLECULAR AND CELLULAR BIOLOGY 22(18) 6375-6383 2002年9月
The association of hypermethylation of multiple genes including DAP-kinase with recurrence in superficial bladder cancers

Cancer Research 2002年
The association of hypermethylation of multiple genes including DAP-kinase with recurrence in superficial bladder cancers

Cancer Research 62, 4048-4053 2002年
High expression of the Cap43 gene in infiltrating macrophages of human renal cell carcinomas

A Nishie, K Masuda, M Otsubo, T Migita, M Tsuneyoshi, K Kohno, T Shuin, S Naito, M Ono, M Kuwano

CLINICAL CANCER RESEARCH 7(7) 2145-2151 2001年7月
Retrovirus insertion and transcriptional activation of the multidrug-resistance gene in leukemias treated by a chemotherapeutic agent in vivo

J Nagayama, M Iino, Y Tada, H Kusaba, A Kiue, K Ohshima, M Kuwano, M Wada

BLOOD 97(3) 759-766 2001年2月
Nuclear expression of tthe Y-box binding protein, YB-1, as a novel marker of disease progression in non-small-cell lung cancer.

Clin. Cancer Res. 7, 3151-3155 2001年
The accumulation of angiostatin-like fragments in human prostate carcinoma.

Clin. Cancer Res. 7, 2750-2756 2001年
Identification of the apical membrane-targeting signal of the multidrug resistance-associated protein 2(MRP2/MOAT).

J. Biol. Chem. 276(24) 20876-20881 2001年
Anigiogenesis factors.

Int. Med. 40 565-572 2001年
YB-1 binds preferentially to single-stranded nucleic acid and exhibit 3'-5' exonuclease activity.

Nucl. Acids Res. 29 1200-1207 2001年
Interferon gamma-dependent induction of thymidine phosphorylase/platelet-derived endothelial growth factor through gamma-activated sequence-like element in human macrophages

H Goto, K Kohno, S Sone, S Akiyama, M Kuwano, M Ono

CANCER RESEARCH 61(2) 469-473 2001年1月
Direct interaction of p53 with the Y-box binding protein, YB-1: a mechanism for regulation of human gene expression

T Okamoto, H Izumi, T Imamura, H Takano, T Ise, T Uchiumi, M Kuwano, K Kohno

ONCOGENE 19(54) 6194-6202 2000年12月
MDR1 gene overexpression and altered degree of methylation at the promoter region in bladder cancer during chemotherapeutic treatment

Y Tada, M Wada, K Kuroiwa, N Kinugawa, T Harada, J Nagayama, M Nakagawa, S Naito, M Kuwano

CLINICAL CANCER RESEARCH 6(12) 4618-4627 2000年12月
Molecular analysis of mechanisms regulating drug sensitivity and the development of new chemotherapy strategies for genitourinary carcinomas

S Naito, H Koga, A Yokomizo, N Sakamoto, S Kotoh, M Nakashima, A Kiue, M Kuwano

WORLD JOURNAL OF SURGERY 24(10) 1183-1186 2000年10月
The activity of soluble VCAM-1 in angiogenesis stimulated by IL-4 and IL-13

J Fukushi, M Ono, W Morikawa, Y Iwamoto, W Kuwano

JOURNAL OF IMMUNOLOGY 165(5) 2818-2823 2000年9月
Increased expression of an ATP-binding cassette superfamily transporter, multidrug resistance protein 2, in human colorectal carcinomas

E Hinoshita, T Uchiumi, K Taguchi, N Kinukawa, M Tsuneyoshi, Y Maehara, K Sugimachi, M Kuwano

CLINICAL CANCER RESEARCH 6(6) 2401-2407 2000年6月
Angiostatin generation by cathepsin D secreted by human prostate carcinoma cells.

J. Biol. Chem. 275(49) 38912-38920 2000年
Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma : possible involvement of TNF α and IL-1 α.

Int. J. Cancer 85(2) 182-188 2000年
Structural basis for the regulation of UDP-N-acetyl-alpha-D-galactosamine: Polypeptide N-acetylgalactosaminyl transferase-3 gene expression in adenocarcinoma cells

M Nomoto, H Izumi, T Ise, K Kato, H Takano, G Nagatani, K Shibao, R Ohta, T Imamura, M Kuwano …

CANCER RESEARCH 59(24) 6214-6222 1999年12月

もっとみる

書籍等出版物

1

Regulation of angiogenesis by growth factors.

Gann Monograph, on Cancer Research, In Growth Factors in Cell Growth, Morphogenesis and Transformation 1994年

所属学協会

6

共同研究・競争的資金等の研究課題

6