NAKASHIMA Mikiro

J-GLOBAL         Last updated: Nov 6, 2019 at 11:23
 
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Name
NAKASHIMA Mikiro
Affiliation
Nagasaki University
Section
Graduate School of Biomedical Sciences
Job title
Professor
Degree
(BLANK)(Nagasaki University), Doctor(Pharmaceutical Scencies)(Kyushu University)

Research Areas

 
 

Academic & Professional Experience

 
Jan 1995
 - 
Today
Ph.D.(Kyushu University)
 
2003
 - 
2005
 Associate Professor,Department of Pharmaceutical Services,University Hospital of Medicine and Dentistry,Nagasaki University
 
2003
 - 
2005
 Others,Department of Pharmaceutical Services,University Hospital of Medicine and Dentistry,Nagasaki University
 
2002
 - 
2005
 Associate Professor,Pharmaceutical Sciences,Pharmaceutical Sciences,Graduate School of Biomedical Sciences,Nagasaki University
 
1994
 - 
2005
 Staff,School of Pharmaceutical Sciences,Nagasaki University
 
2005
   
 
 Professor,Pharmaceutical Sciences,Pharmaceutical Sciences,Graduate School of Biomedical Sciences,Nagasaki University
 
2001
 - 
2003
 Associate Professor,Nagasaki University
 
2000
 - 
2003
 Others,Nagasaki University
 
2001
 - 
2002
 Staff,School of Allied Medical Sciences,Nagasaki University
 
2001
 - 
2002
 Associate Professor,Graduate School of Pharmaceutical Sciences,Nagasaki University
 
2000
 - 
2001
 Lecturer,Nagasaki University
 
2001
   
 
 Lecturer,Graduate School of Pharmaceutical Sciences,Nagasaki University
 
1993
 - 
2000
 Research Associate,Nagasaki University
 
1984
 - 
1993
 Medical Staff,Nagasaki University
 

Education

 
 
 - 
1984
Graduate School, Division of Pharmaceutical Sciences, Nagasaki University
 
 
 - 
1982
Faculty of Pharmaceutical Science, Nagasaki University
 

Published Papers

 
Relationship between constipation and medication
Ueki T, Nakashima M
J UOEH   41(2) 145-151   Jun 2019   [Refereed]
Proteomic analysis and ATP assay reveal a positive effect of artificial cerebral spinal fluid perfusion folloing microdialysis sampling on repair of probe-induced brain damege
K Ohyama, Y Ikeshita, Y Fuchigami, S Kawakami, M N Nakashima, M Nakashima
ournal of Neuroscience Methods   315 1-5   2019   [Refereed]
Combination index of the concentration and in vivo antagonism activity of racemic warfarin and its metabolites to assess individual drug responses
S Kobayashi, K Ishii, Y Yamada, E Ryu, J Hashizume, S Nose, T Hara, M Nakashima, K Ohyama
Journal of Thrombosis and Thrombolysis   47 467-472   2019   [Refereed]
Gene delivery system of pDNA using the blood glycoprotein fetuin
Kodama Y, Hanamura H, Muro T, Nakagawa H, Kurosaki T, Nakamura T, Kitahara T, Kawakami S, Nakashima M, Sasaki H
J Drug Target   26 604-609   2018   [Refereed]
Selective, sensitive and comprehensive detection of immune complex antigens by immune complexome analysis with papain-digestion and elution
Aibara N, Kamohara C, Chauhan AK, Kishikawa N, Miyata Y, Nakashima M, Kuroda N, Ohyama K
J Immunol Methods   461 85-90   2018   [Refereed]
Tracking by a Questionnaire for Interprofessional Education Taking Persons by Consortium for Home Health Care in Nagasaki
Journal of Kyushu Pharmacy   71(1) 21-25   2017   [Refereed]
Computational study of the competitive binding of valproic acid glucuronide and carbapenem antibiotics to acylpeptide hydrolase
Ishikawa T, Ohtaki H, Mizuta S, Kuriyama M, Onomura O, Higuchi N, Nakashima MN, Nakashima M, Ohyama K
Drug Metab Pharmacokinet   32 201-207   2017   [Refereed]
Transcriptome analysis of human liver in chimeric PXB-Mouse® for risk marker identification associated with drug-induced liver injury
Enomoto H, Tachiki H, Shimada T, Nagatsuka S, Nakashima M
Toxicology Letters   258S S90   2016   [Refereed]
Evaluation for peritoneal injury at an early stage using dual macromolecular markers
Hirata H, Fumoto S, Miyamoto H, Nakashima M, Nakayama M, Nishida K
Biol. Pharm. Bull   39 1581-1587   2016   [Refereed]
Identification of positive biomarker genes for drug-induced liver injury using chimeric PXB-Mouse® with highly humanized liver
Enomoto H, Tachiki H, Shimada T, Nagatsuka S, Nakashima M
Toxicology Letters   238S S250   2015
Novel diagnostic method of peritoneal injury using dual macromolecular markers
Hirata H, Miyamoto H, Shimokawa K, Nakashima M, Nakayama M, Fumoto S, Nishida K
Biol. Pharm. Bull   37 262-267   2014   [Refereed]
Changes in hepatic gene expression induced by various statin formulations in chimeric PXB-Mouse with highly humanized liver
Nakashima M, Tachiki H, Enomoto H, Shimada T, Nagatsuka S
Toxicology Letters   221S S194   2013   [Refereed]
The role of fibronectin in pulmonary gene transfer following intravenous administration of lipoplex in mice
Yoshikawa N, Fumoto S, Nakashima M, Shimokawa K, Miyamoto H, Nishida K
Biol Pharm Bull   36 1807-1813   2013   [Refereed]
Evaluation for effect of hypothermia on the disposition of 4-nitrophenol in rats by in-vitro metabolism study and rat liver perfusion system
Miyamoto H, Matsueda S, Komori K, Fumoto S, Nakashima M, Yoshikawa N, Hirata H, Shimokawa K, Ohwaki Y, Nishida K
J Pharm Pharmacol   65(10) 1536-1540   2013   [Refereed]
Investigation of Protective Effects of Sodium Hyaluronate Eyedrop Against Corneal Epithelial Disorders Using an Electrophysiological Method
Araki R, Nakashima M, Teshima M, Owaki Y, Nakashima M N, Uematsu M, Kitaoka T, Nakamura T, Kitahara T, Sasaki H
J Ocul Pharmacol Ther   28 251-258   2012   [Refereed]
T.Kondoh, A.Kanno, H.Itoh, M.Nakashima, R.Honda, M.Kojima, M.Noguchi, H.Nakane, H.Nozaki, H.Sasaki, T.Nagai, R.Kosaki, N.Kakee, T.Okuyama, M.Fukuda, M.Ikeda, Y.Shibata, H.Moriuchi
The International Journal of Psychiatry in Medicine   41(1) 71-89   2011   [Refereed]
T.Ueki, K.Nagai, N.Ooe, M.N.Nakashima, K.Nishida, J.Nakamura, M.Nakashima
Yakugaku Zasshi   131(3) 469-476   2011   [Refereed]
T.Ueki, K.Nagai, Y.Mizukami, A.Takahashi, N.Ooe, M.N.Nakashima, K.Nishida, J.Nakamura, M.Nakashima
Yakugaku Zasshi   131(8) 1225-1232   2011   [Refereed]
T.Mine, H.Ishii, S.Nakajima, N.Yoshikawa, H.Miyamoto, M.Nakashima, S.Fumoto, K.Nishida
Biol. Pharm. Bull.   34(9) 1514-1517   2011   [Refereed]
R.Araki, E.Yukawa, M.N.Nakashima, H.Fukuchi, H.Sasaki, K.Yano, M.Nakashima
Ther. Drug Monit.   33(6) 750   2011   [Refereed]
T.Nakamura, M.Teshima, T.Kitahara, H.Sasaki, M.Uematsu, T.Kitaoka, M.Nakashima, K.Nishida, J.Nakamura, S.Higuchi
Biol. Pharm. Bull.   33(1) 107-110   2010   [Refereed]
H.Fukuchi, M.Nakashima, R.Araki, N.Komiya, M.Hayano, K.Yano, H.Sasaki, E.Yukawa
J. Clin. Pharm. Ther.   34 329-336   2009   [Refereed]
T.Yoshioka, S.Yoshida, T.Kurosaki, M.Teshima, K.Nishida, J.Nakamura, M.Nakashima, H.To, T.Kitahara, H.Sasaki
J.Liposome.Res.   19(2) 141-147   2009   [Refereed]
S.Fumoto, J.Nishi, H.Ishii, X.Wang, H.Miyamoto, N.Yoshikawa, M.Nakashima, J.Nakamura, K. Nishida
Mol. Pharmaceut.   6 1170-1179   2009   [Refereed]
S.Fumoto, M.Tsuchimochi, J.Nishi, H.Ishii, Y.Kodama, M.Nakashima, H.Sasaki, J.Nakamura, K.Nishida
Biol. Pharm. Bull.   32(7) 1298-1302   2009   [Refereed]
Ueki T, Tasaki N, Yoshida T, Ooe N, Nishida K, Nakamura J, Nakashima M
Jpn J Pharm Health Care Sci   34(9) 865-870   2008   [Refereed]
Nishi J, Fumoto S, Ishii H, Kodama Y, Nakashima M, Sasaki H, Nakamura J, Nishida K
Eur J Pharm Biopharm   69 633-639   2008   [Refereed]
Nakashima M, Nakamura T, Teshima M, To H, Uematsu M, Kitaoka T, Taniyama K, Nishida K, Nakamura J, Sasaki H
J Ocul Pharm Ther   24 43-51   2008   [Refereed]
Sakanaka K, Kawazu K, Tomonari M, Kitahara T, Nakashima M, Nishida K, Nakamura J, Sasaki H, Higuchi S
Biol Pharm Bull   31(5) 970-975   2008   [Refereed]
Kodama Y, Fumoto S, Nishi J, Nakashima M, Sasaki H, Nakamura J, Nishida K
Biol Pharm Bull   31(5) 1049-1052   2008   [Refereed]
Miyanaga K, Yoshioka T, Nakagawa H, Kitahara T, To H, Ichikawa N, Nakashima M, Nishida K, Nakamura J, Sasaki H
Biol Pharm Bull   31(8) 1585-1589   2008   [Refereed]
Sakanaka K, Kawazu K, Tomonari M, Kitahara T, Nakashima M, Nishida K, Nakamura J, Sasaki H, Higuchi S
Biol Pharm Bull   31(8) 1590-1595   2008   [Refereed]
J. Nishi, S. Fumoto, H. Ishii, Y. Kodama, M. Nakashima, H. Sasaki, J. Nakamura, K. Nishida
J. Gastroenterology   43(12) 912-919   2008   [Refereed]
S. Fumoto, Y. Nakashima, K. Nishida, Y. Kodama, J. Nishi, M. Nakashima, H. Sasaki, N. Otsuka, J. Nakamura
Pharmaceut. Res.   24 1891-1896   2007   [Refereed]
Koyo Nishida, Madoka Okazaki, Ryuichi Sakamoto, Natsuko Inaoka, Hideaki Miyake, Shintaro Fumoto, Junzo Nakamura, Mikiro Nakashima, Hitoshi Sasaki, Mikio Kakumoto, Toshiyuki Sakaeda
Biological and Pharmaceutical Bulletin   30(9) 1763-1767   2007   [Refereed]
J. Nakamura, S. Fumoto, R. Kawanami, Y. Kodama, J. Nishi, M. Nakashima, H. Sasaki, K. Nishida
Biological and Pharmaceutical Bulletin   30(5) 941-945   2007   [Refereed]
J. Nakamura, S. Fumoto, K. Ariyoshi, Y. Kodama, J. Nishi, M. Nakashima, H. Sasaki, K. Nishida
Biological and Pharmaceutical Bulletin   30(4) 729-732   2007   [Refereed]
Tadahiro Nakamura, Mikiko Yamada, Mugen Teshima, Mikiro Nakashima, Hideto To, Nobuhiro Ichikawa, Hitoshi Sasaki
Biological and Pharmaceutical Bulletin   30(12) 2360-2364   2007   [Refereed]
Ide N, Nagasayu T, Matsumoto K, Tagawa T, Tanaka K, Taguchi T, Sumida Y, Nakashima M
Journal of Thoracic and Cardiovascular Surgery   133(2) 548-553   2007   [Refereed]
J. Nakamura, S. Fumoto, K. Shoji, Y. Kodama, J. Nishi, M. Nakashima, H. Sasaki, K. Nishida
Biological and Pharmaceutical Bulletin   29(10) 2082-2086   2006   [Refereed]
K. Sakanaka, K. Kawazu, K. Nishida, J. Nakamura, M. Nakashima, T. Nakamura, A. Oshita, N. Ichikawa, H. Sasaki
Biological and Pharmaceutical Bulletin   29(10) 2143-2147   2006   [Refereed]
Yuki Tada, Takashi Kitahara, Takashi Yoshioka, Tadahiro Nakamura, Nobuhiro Ichikawa, Mikiro Nakashima, Koyo Nishida, Junzo Nakamura, Hitoshi Sasaki
Biological and Pharmaceutical Bulletin   29(8) 1712-1716   2006   [Refereed]
Kouichi Kawazu, Akemi Oshita, Tadahiro Nakamura, Mikiro Nakashima, Nobuhiro Ichikawa, Hitoshi Sasaki
Biological and Pharmaceutical Bulletin   29(4) 846-849   2006   [Refereed]
Hitoshi Sasaki, Shohei Yoshida, Takashi Kitahara, Takashi Yoshioka, Hiroo Nakagawa, Tadahiro Nakamura, Nobuhiro Ichikawa, Koyo Nishida, Junzo Nakamura, Mikiro Nakashima
Int. J. Pharm.   318 139-145   2006   [Refereed]
Mugen Teshima, Shintaro Fumoto, Koyo Nishida, Junzo Nakamura, Kaname Ohyama, Tadahiro Nakamura, Nobuhiro Ichikawa, Mikiro Nakashima, Hitoshi Sasaki
J. Control. Release   112 320-328   2006   [Refereed]
Mugen Teshima, Shigeru Kawakami, Shintaro Fumoto, Koyo Nishida, Junzo Nakamura, Mikiro Nakashima, Hiroo Nakagawa, Nobuhiro Ichikawa, Hitoshi Sasaki
Biol. Pharm. Bull.   29(7) 1436-1440   2006   [Refereed]
T.Kitahara, Y.Aoyama, Y.Hirakata, S.Kamihira, S.Kohno, N.Ichikawa, M.Nakashima, H.Sasaki, S.Higuchi
Int. J. Antimicrob. Agents   27 51-57   2006   [Refereed]
Ryu Hirayama, Koyo Nishida, Shintaro Fumoto, Mikiro Nakashima, Hitoshi Sasaki, Junzo Nakamura
Biological and Pharmaceutical Bulletin   28(11) 2166-2169   2005   [Refereed]
Koyo Nishida, Rie Fujiwara, Yukinobu Kodama, Shintaro Fumoto, Takahiro Mukai, Mikiro Nakashima, Hotoshi Sasaki, Junzo Nakamura
Pharm. Res.   22 1331-1337   2005   [Refereed]
Koyo Nishida, Akiko Kuma, Shintaro Fumoto, Mikiro Nakashima, Hitoshi Sasaki, Junzo Nakamura
J. Pharm. Pharmacol.   57 1073-1077   2005   [Refereed]
Junzo Nakamura, Kazuko Kobayashi, Shintaro Fumoto, Junya Nishi, Takahiro Mukai, Mikiro Nakashima, Hitoshi Sasaki, Koyo Nishida
Biological and Pharmaceutical Bulletin   28(6) 1049-1053   2005   [Refereed]
Junji IWASHITA, Seiji KODAMA, Mikiro NAKASHIMA, Hitoshi SASAKI, Kotaro TANIYAMA, Masami WATANABE
Journal of Radiation Research   46(2) 191-195   2005   [Refereed]
Koyo Nishida, Manabu Kamenosono, Akiko Kuma, S.hintaro Fumoto, Takahiro Mukai, Mikiro Nakashima, Hitoshi Sasaki , Junzo Nakamura
J. Drug Target.   13 215-223   2005   [Refereed]
Ryu Hirayama, Koyo Nishida, Shintaro Fumoto, Mikiro Nakashima, Hitoshi Sasaki, Junzo Nakamura
Biological and Pharmaceutical Bulletin   28(1) 181-184   2005   [Refereed]
Dramatic improvement on donepezil in down’s syndrome-associated cognitive impairment (jointly worked)
Tatsuro Kondoh, Nagisa Amamoto, Tomoki Doi, Hitomi Hamada, Yoji Ogawa, Mikiro Nakashima, Hitoshi Sasaki, Katsuyo Aikawa, Tatsuhiko Tanaka, Mizue Aoki, Junji Harada, Hiroyuki Moriuchi
Ann. Pharmacother.   39 563-566   2005   [Refereed]
Tatsuro Kondoh, Mikiro Nakashima, Hitoshi Sasaki, Hiroyuki Moriuchi
Ann. Pharmacother.   39 572-573   2005   [Refereed]
Koyo Nishida, Naoki Tomiyama, Takahiro Mukai, Mikiro Nakashima, Hitoshi Sasaki, Junzo Nakamura
Eur. J. Pharmaceut. Biopharmaceut.   58 705-711   2004   [Refereed]
Ryu Hirayama, Koyo Nishida, Shintaro Fumoto, Mikiro Nakashima, Hitoshi Sasaki, Junzo Nakamura
Biological and Pharmaceutical Bulletin   27(10) 1697-1699   2004   [Refereed]
Hideo Shiota, Mikiro Nakashima, Hideyuki Terazono, Hitoshi Sasaki, Koyo Nishida, Junzo Nakamura, Kotaro Taniyama
Legal Medicine   6(4) 224-232   2004   [Refereed]
Shigeru Kawakami, Ayaka Harada, Koji Sakanaka, Koyo Nishida, Junzo Nakamura, Toshiyuki Sakaeda, Nobuhiro Ichikawa, Mikiro Nakashima, Hitoshi Sasaki
Int. J. Pharm.   278 255-262   2004   [Refereed]
Takashi Kitahara, Nao Koyama, Junichi Matsuda, Yuko Aoyama, Yoichi Hirakata, Shimeru Kamihira, Shigeru Kohno, Mikiro Nakashima, Hitoshi Sasaki
Biological and Pharmaceutical Bulletin   27(9) 1321-1326   2004   [Refereed]
Mugen Teshima, Shigeru Kawakami, Koyo Nishida, Junzo Nakamura, Toshiyuki Sakaeda, Hideyuki Terazono, Takashi Kitahara, Mikiro Nakashima, Hitoshi Sasaki
J. Control. Release   97 211-218   2004   [Refereed]
Koyo Nishida, Seiichi Nose, Akiko Kuma, Takahiro Mukai, Mikiro Nakashima, Hitoshi Sasaki, Junzo Nakamura
J. Pharm. Pharmacol.   56 683-687   2004   [Refereed]
Koji Sakanaka, Kouichi Kawazu, Masahide Tomonari, Takashi Kitahara, Mikiro Nakashima, Shigeru Kawakami, Koyo Nishida, Junzo Nakamura, Hitoshi Sasaki
Pharm. Res.   21 770-776   2004   [Refereed]
Takahiro Mukai, Kunihiro Mera, Koyo Nishida, Mikiro Nakashima, Hitoshi Sasaki, Junzo Nakamura
Biological and Pharmaceutical Bulletin   27(4) 595-597   2004   [Refereed]
Ryu Hirayama, Shigeru Kawakami, Koyo Nishida, Mikiro Nakashima, Hitoshi Sasaki, Toshiyuki Sakaeda, Junzo Nakamura
Pharm. Res.   20 328-332   2003   [Refereed]
Hitoshi Sasaki, Toshiaki Nagano, Koji Sakanaka, Shigeru Kawakami, Koyo Nishida, Junzo Nakamura, Nobuhiro Ichikawa, Junji Iwashita, Tadahiro Nakamura, Mikiro Nakashima
J. Control. Release   92 241-247   2003   [Refereed]
Junzo Nakamura, Tomomi Horimoto, Ryu Hirayama, Takahiro Mukai, Mikiro Nakashima, Hitoshi Sasaki, Koyo Nishida
Biological and Pharmaceutical Bulletin   26(12) 1761-1764   2003   [Refereed]
Takashi Kitahara, Nao Koyama, Junichi Matsuda, Yoichi Hirakata, Shimeru Kamihira, Shigeru Kohno, Mikiro Nakashima, Hitoshi Sasaki
Biological and Pharmaceutical Bulletin   26(9) 1229-1234   2003   [Refereed]
Junzo Nakamura, Tomomi Horimoto, Ryu Hirayama, Takahiro Mukai, Mikiro Nakashima, Hitoshi Sasaki, Koyo Nishida
Biological and Pharmaceutical Bulletin   26(7) 1049-1051   2003   [Refereed]
Koyo Nishida, Tominori Honda, Mikiro Nakashima, Hitoshi Sasaki, Junzo Nakamura
Biological and Pharmaceutical Bulletin   26(7) 988-993   2003   [Refereed]
Shigeru Kawakami Nao Ohshima, Ryu Hirayama ,Masami Hirai, Takashi Kitahara, Toshiyuki Sakaeda ,Takahiro Mukai, Koyo Nishida, Junzo Nakamura, Mikiro Nakashima, Hitoshi Sasaki
Biological and Pharmaceutical Bulletin   25(8) 1072-1076   2002   [Refereed]
Koyo Nishida, Seiichi Nose, Akiko Kuma, Takahiro Mukai, Shigeru Kawakami, Mikiro Nakashima, Hitoshi Sasaki, Toshiyuki Sakaeda, Junzo Nakamura
J. Pharm. Pharmacol.   54 1005-1009   2002   [Refereed]
Takahiro Mukai, Kunihiro Mera, Koyo Nishida, Mikiro Nakashima, Hitoshi Sasaki, Toshiyuki Sakaeda, Junzo Nakamura
Biological and Pharmaceutical Bulletin   25(11) 1494-1497   2002   [Refereed]
Shigeru Kawakami, Tomomi Horimoto, Koyo Nishida, Ryu Hirayama, Takahiro Mukai, Mikiro Nakashima, Hitoshi Sasaki, Toshiyuki Sakaeda, Junzo Nakamura
Biological and Pharmaceutical Bulletin   25(7) 928-930   2002   [Refereed]
Shigeru Kawakami, Ryu Hirayama, Keiko Shoji, Rie Kawanami, Koyo Nishida、Mikiro Nakashima, Hitoshi Sasaki, Toshiyuki Sakaeda, Junzo Nakamura
Biochemical and Biophysical Research Communications   294(1) 46-50   2002   [Refereed]
Shigeru Kawakami, Koyo Nishida, Takahiro Mukai, Kenzo Yamamura, Kazuko Kobayashi, Toshiyuki Sakaeda, Junzo Nakamura, Mikiro Nakashima, Hitoshi Sasaki
Journal of Pharmaceutical Sciences   90(12) 2113-2120   2001   [Refereed]
Koyo Nishida, Yayoi Yoshida, Takahiro Mukai, Shigeru Kawakami, Toshiyuki Sakaeda, Mikiro Nakashima, Hitoshi Sasaki, Junzo Nakamura
Journal of Pharmacy and Pharmacology   53(10) 1341-1346   2001   [Refereed]
Shigeru Kawakami, Kenzo Yamamura, Takahiro Mukai, Koyo Nishida, Junzo Nakamura, Toshiyuki Sakaeda, Mikiro Nakashima, Hitoshi Sasaki
Journal of Pharmacy and Pharmacology   53(8) 1157-1161   2001   [Refereed]
Shigeru Kawakami, Koyo Nishida, Takahiro Mukai, Kenzo Yamamura, Junzo Nakamura, Toshiyuki Sakaeda, Mikiro Nakashima, Hitoshi Sasaki
Journal of Controlled Release   76(3) 255-263   2001   [Refereed]
Katsuro Ichinose, Naoki Tomiyama, Mikiro Nakashima, Yuichi Ohya, Masataka Ichikawa, Tatsuro Ouchi, Takashi Kanematsu
Anti-Cancer Drugs   11 33-38   2000   [Refereed]
Hitoshi SASAKI, Kenzo YAMAMURA, Takahiro MUKAI, Koyo NISHIDA, Junzo NAKAMURA, Mikiro NAKASHIMA, Masataka ICHIKAWA
Biological and Pharmaceutical Bulletin   23(12) 1524-1527   2000   [Refereed]
Yoshiharu TOKUNAGA, Mikiro NAKASHIMA, Hitoshi SASAKI, Naoki TOMIYAMA, Mihoko N. NAKASHIMA, Masataka ICHIKAWA, Makio KAMINOGO, Shobu SHIBATA
Biological and Pharmaceutical Bulletin   23(12) 1491-1496   2000   [Refereed]
Hitoshi SASAKI, Kenzo YAMAMURA, Takahiro MUKAI, Koyo NISHIDA, Junzo NAKAMURA, Mikiro NAKASHIMA, Masataka ICHIKAWA
Biological and Pharmaceutical Bulletin   23(11) 1352-1356   2000   [Refereed]
Kenzo Yamamura, Hitoshi Sasaki, Mikiro Nakashima, Masataka Ichikawa, Takahiro Mukai, Koyo Nishida, Junzo Nakamura
Pharmaceutical Research   16(10) 1596-1601   1999   [Refereed]
Hitoshi SASAKI, Satsuki KASHIWAGI, Takahiro MUKAI, Koyo NISHIDA, Junzo NAKAMURA, Mikiro NAKASHIMA, Masataka ICHIKAWA
Biological and Pharmaceutical Bulletin   22(9) 961-965   1999   [Refereed]
Mikiro NAKASHIMA, Katsuro ICHINOSE, Takashi KANEMATSU, Tatsunori MASUNAGA, Yuichi OHYA, Tatsuro OUCHI, Naoki TOMIYAMA, Hitoshi SASAKI, Masataka ICHIKAWA
Biological and Pharmaceutical Bulletin   22(7) 756-761   1999   [Refereed]
Hitoshi SASAKI, Kenzo YAMAMURA, Takahiro MUKAI, Koyo NISHIDA, Junzo NAKAMURA, Mikiro NAKASHIMA, Masataka ICHIKAWA
Biological and Pharmaceutical Bulletin   22(11) 1253-1255   1999   [Refereed]
Enhancement of ocular drug penetration (jointly worked)
Hitoshi Sasaki, Kenzo Yamamura, Takahiro Mukai, Koyo Nishida, Junzo Nakamura, Mikiro Nakashima, Masataka Ichikawa
Crit. Rev. Ther. Drug Carr. Systems   16 85-146   1999   [Refereed]
Hitoshi Sasaki, Satsuki Kashiwagi, Takahiro Mukai, Koyo Nishida, Junzo Nakamura, Mikiro Nakashima, Masataka Ichikawa
Biol. Pharm. Bull.   22(9) 956-960   1999   [Refereed]
Mikiro Nakashima, Shobu Shibata, Yoshiharu Tokunaga, Hideshi Fujita, Takeo Anda, Koji Arizono, Naoki Tomiyama, Hitoshi Sasaki, Masataka Ichikawa
J. Pharm. Pharmacol.   49 777-780   1997   [Refereed]
In vivo ocular microdialysis to monitor ocularly applied cyclosporin in the anterior chamber of rabbits (jointly worked)
Mikiro Nakashima, Hitoshi Sasaki, Akihiro Ohira, Tsugio Amemiya, Kenzo Yamamura, Kenji Matsuyama, Masataka Ichikawa
Pharmaceutical Sciences   3 179-182   1997   [Refereed]
Antitumour effects of 4-pyridoxate diammine hydroxy platinum, a novel cisplatin derivative, against malignant gliomas in vitro and in vivo: A comparison with cisplatin (jointly worked)
Yoshiharu Tokunaga, Mikiro Nakashima, Shobu Shibata, Hideshi Fujita, Takeo Anda, Humayun Khalid, Masayuki Kuzuya, Hitoshi Sasaki, Masataka Ichikawa
Pharmaceutical Sciences   3 353-356   1997   [Refereed]
In vivo ocular pharmacokinetic model for designing dosage schedules and formulations of ophthalmic drugs in human (jointly worked)
Hitoshi Sasaki, Kenzo Yamamura, Takahiro Mukai, Koyo Nishida, Junzo Nakamura, Mikiro Nakashima, Masayoshi Ogasawara, Masataka Ichikawa
Acta Medica Nagasakiensia   42 45-50   1997   [Refereed]
Mikiro NAKASHIMA, Mei Feng ZHAO, Mihoko N. NAKASHIMA, Masaharu SAKURAI, Hitoshi SASAKI, Kenji MATSUYAMA, Masataka ICHIKAWA
Biological and Pharmaceutical Bulletin   19(7) 988-994   1996   [Refereed]
Mikiro Nakashima, Mei Feng Zhao, Hisami Ohya, Masaharu Sakurai, Hitoshi Sasaki, Kenji Matsuyama, Masataka Ichikawa
J. Pharm. Pharmacol.   48 1143-1146   1996   [Refereed]
Kenji Matsuyama, Mikiro Nakashima, Yukiko Nakaboh, Masataka Ichikawa, Tadanori Yano, Shuji Satoh
Pharmaceutical Research   11(5) 684-686   1994   [Refereed]
Mikiro NAKASHIMA, Naoko TAKEUCHI, Motoko HAMADA, Kenji MATSUYAMA, Masataka ICHIKAWA, Shigeru GOTO
Biological and Pharmaceutical Bulletin   17(12) 1630-1634   1994   [Refereed]
Kenji Matsuyama, Mikiro Nakashima, Masataka Ichikawa, Tadanori Yano, Shuji Satoh, Shigeru Goto
Biol. Pharm. Bull.   17(10) 1395-1398   1994   [Refereed]

Misc

 
Biological and Pharmaceutical Bulletin   31(5) 970-975   2008
Kei Miyanaga, Takashi Yoshioka, Hiroo Nakagawa, Takashi Kitahara, Hideto To, Nobuhiro Ichikawa, Mikiro Nakashima, Koyo Nishida, Junzo Nakamura, Hitoshi Sasaki
Biological and Pharmaceutical Bulletin   31(8) 1585-1589   2008
Koji Sakanaka, Kouichi Kawazu, Masahide Tomonari, Takashi Kitahara, Mikiro Nakashima, Koyo Nishida, Junzo Nakamura, Hitoshi Sasaki, Shun Higuchi
Biological and Pharmaceutical Bulletin   31(8) 1590-1595   2008
Mugen Teshima, Shigeru Kawakami, Shintaro Fumoto, Koyo Nishida, Junzo Nakamura, Mikiro Nakashima, Hiroo Nakagawa, Nobuhiro Ichikawa, Hitoshi Sasaki
Biological and Pharmaceutical Bulletin   29(7) 1436-1440   2006
In vitro activity of lauric acid or myristylamine in combination with six antimicrobialagents against MRSA
27 51-57   2006
Dramatic improvement on donepezil in down’s syndrome-associated cognitive impairment
39 563-566   2005
A pharmacokinetics study on donepezil in down's syndrome patient
39 572-573   2005
Enhancement of ocular drug penetration
16 85-146   1999
Drug absorption behavior after periocular injections
22 965-960   1999
In vivo ocular microdialysis to monitor ocularly applied cyclosporin in the anterior chamber of rabbits
3 179-182   1997
Antitumour effects of 4-pyridoxate diammine hydroxy platinum, a novel cisplatin derivative, against malignant gliomas in vitro and in vivo: A comparison with cisplatin
3 353-356   1997
In vivo ocular pharmacokinetic model for designing dosage schedules and formulations of ophthalmic drugs in human
42 45-50   1997
Kenji MATSUYAMA, Mikiro NAKASHIMA, Masataka ICHIKAWA, Tadanori YANO, Shuji SATOH, Shigeru GOTO
Biological and Pharmaceutical Bulletin   17(10) 1395-1398   1994
SAMIRKUMAR PODDER, MIKIRO NAKASHIMA, TADAHIRO NAKAMURA, HITOSHI SASAKI, JUNZO NAKAMURA, JUICHIRO SHIBASAKI
Journal of Pharmacobio-Dynamics   9(11) 917-922   1986
First-pass metabolism of drug and its prodrug in dogs
8 s150-s150   1985

Conference Activities & Talks

 
Reliable Screening for Drug Repositioning Study against Liver Disease and Toxicology by Gene Expression Analysis of a Model Mouse Transplanted with Human Liver
K.Ohyama, H.Soki, H.Miyamoto, H.Enomoto, H.Tachiki, S.Nagatsuka, M.N.Nakashima, M.Nakashima
SOT 56th Annual Meeting and ToxExpo   Mar 2017   
Effects of irinotecan on hepatic gene expression in chimeric PXB-mouse with highly humanized liver
M. Nakashima, H. Enomoto, H. Tachiki, T. Shimada, S. Nagatsuka
Eurotox 2015   Sep 2014   
Changes in hepatic gene expression induced by various statin formulations in chimeric PXB-Mouse with highly humanized liver
M. Nakashima, H. Tachiki, H. Enomoto, T. Shimada, S. Nagatsuka
Eurotox 2014   Sep 2013   
Advanced interprofessional education program specially focused on home healthcare by nagasaki pharmaceutical and nursing sciences consortium
Mikiro Nakashima, Mugen Teshima, Hitomi Sakamoto, Izumi Ohmachi, Hideko Urata, Nobuou Matsusaka, Sachiko Matsumoto, Ryuzo Sakakibara, Morio Nakayama
The 6th International Conference for Interprofessional Education and Collaborative Practice   Oct 2012   
Evaluation of Hepatotoxic Equivalency by Comparing Changes in Hepatic Gene Expression Induced by Two Different Formulations of Atorvastatin in Chimeric PXB-mouse with Highly Humanized Liver
M. Nakashima, H. Tachiki, T. Shimada, S. Nagatsuka
SOT 51st Annual Meeting   Mar 2012   
Bioequivalency of Two Different Methotrexate Formulations in Hepatic Gene Expression of PXB-mice with Highly Humanized Liver
M.Nakashima, H.Tachiki, T.Shimada, D.Hynes, S.Nagatsuka
SOT 50th Anniversary Annual Meeting   Mar 2011   
Cross sectional study on relationship between constipation snd medication in consideration of sleep disorder
T.Ueki, K.Nagai, M.Teshima, M.Nakashima
45th ASHP Midyear Clinical Meeting 2010   Dec 2010   
Effects of antiarrhythmic agents on beating rhythm of cultured cardiomyocyte networks on an agarose microchamber chip
Y.Ohwaki, R.Araki, R.Tominaga, H.Terazono, H.To, H.Sasaki, M.Nakashima
The Second Asian Symposium on Pharmaceutical Sciences   Mar 2009   
Influence of obesity on amiodarone pharmacokinetics in long-term therapy: multiple-trough screen by population pharmacokinetic modeling technique
H. Sasaki, R. Araki, M. Nakashima, H. To, T. Kitahara
42nd ASHP midyear clinical meeting   Dec 2007   
Reticuloenothelial delivery or prolonged blood concentration of prednisolone after intravenous injection of liposomal prednisolone
H. Sasaki, M. Teshima, N. Ichikawa, M. Nakashima, K. Nishida, J. Nakamura
The 3rd Korea-Japan Joint Symposium   Apr 2006   
Usefulness of carbonic anhydrase inhibitors as new agents for visualization of vitreous bodies
M. Uematsu, M. Teshima, M. Nakashima, H. Sasaki, K. Yamada, K. Mishima, T. Kitaoka
2006 ARVO Annual Meeting   Apr 2006   
Optimization of prednisolone pharmacokinetics by sterically stabilized liposomes
M. Teshima, K. Kashiwagi, K. Nishida, J. Nakamura, T. Kitahara, N. Ichikawa, M. Nakashima, H. Sasaki
The 13th NA ISSX / the 20th JSSX Meeting   Oct 2005   
Effects of adipocytokines on CYP mRNA expression and drug metabolism in HepG2
M. Nakashima, N. Taketa, H. Fukuchi, H. Watanabe, H. Terazono, N. Ichikawa, K. Nishida, J. Nakamura, H. Sasaki
The 13th NA ISSX / the 20th JSSX Meeting   Oct 2005   
Gene transfer to the eye utilizing the cationic liposomes after intravitreal injection in rabbits
M. Uematsu, M. Teshima, N. Ichikawa, M. Nakashima, H. Sasaki, T. Kitaoka
ARVO 2005   May 2005   
Electrophysiological study for estimation of corneal epithelial disorders after instillation of eyedrops
M. Uematsu, M. Nakashima, N. Ichikawa, T. Kitaoka, K. Taniyama, H. Sasaki
The 7th Association for Ocular Pharmacology and Therapeutics   Feb 2005   
One-side coated insert as a unique ophthalmic drug delivery system
H. Sasaki, T. Nakamura, T. Kitahara, H. Terazono, N. Ichikawa, M. Nakashima, K. Nishida, J. Nakamura
2004 AAPS Annual Meeting and Exposition   Nov 2004   
H. Sasaki, M. Takenaka, M. Nakashima, T. Yoshioka, H. Terazono, N. Ichikawa
H. Sasaki, M. Takenaka, M. Nakashima, T. Yoshioka, H. Terazono, N. Ichikawa
The 64th World Congress of Pharmacy and Pharmaceutical Sciences (FIP 2004)   Sep 2004   
Electrophysiological study for estimation of corneal epithelial disorders after instillation of antiglaucomatous eyedrops
M. Nakashima, S. Murata, K. Sakanaka, H. Terazono, T. Kitahara, N. Ichikawa, K. Nishida, J. Nakamura, M. Kaibara, K. Taniyama, H. Sasaki
The 2nd World Congress of the Board of Pharmaceutical Sciences of FIP (PSWC 2004)   May 2004   
Prednisolone retention in integrated liposomes by chemical approach and pharmaceutical approach
M. Teshima, S. Kawakami, K. Nishida, J. Nakamura, T. Sakaeda,
The 2nd World Congress of the Board of Pharmaceutical Sciences of FIP (PSWC 2004)   May 2004   
Ocular pharmacokinetic/pharmacodynamic (PK/PD) modeling for bunazosin after instillation
H. Sasaki, K. Sakanaka, K. Kawazu, M. Tomonari, T. Kitahara, M. Nakashima, K. Nishida, J. Nakamura
The 2nd World Congress of the Board of Pharmaceutical Sciences of FIP (PSWC 2004)   May 2004   

Teaching Experience

 
 

Research Grants & Projects

 
Japan Society for the Promotion of Science: Grant-in-Aid for Scientific Research (C)
Project Year: Apr 2017 - Mar 2020    Investigator(s): Mikiro Nakashima
Japan Society for the Promotion of Science: Grant-in-Aid for Scientific Research (C)
Project Year: Apr 2014 - Mar 2017    Investigator(s): Mikiro Nakashima
Japan Society for the Promotion of Science: Grant-in-Aid for Scientific Research (C)
Project Year: Apr 2011 - Mar 2014    Investigator(s): Mikiro Nakashima
Japan Society for the Promotion of Science: Grant-in-Aid for Scientific Research (C)
Project Year: Apr 2008 - Mar 2011    Investigator(s): Mikiro Nakashima
Japan Society for the Promotion of Science: Grant-in-Aid for Scientific Research (C)
Project Year: Apr 2005 - Mar 2007    Investigator(s): Mikiro Nakashima, Junzo Nakamura
JST: Development of advanced measurement and analysis systems
Project Year: Apr 2004 - Mar 2007    Investigator(s): Mikiro Nakashima, Kenji Yasuda
Nagasaki University: Nagasaki University Advanced Promotion Programs
Project Year: Apr 2005 - Mar 2006    Investigator(s): Mikiro Nakashima
Japan Society for the Promotion of Science: Grant-in-Aid for Scientific Research (C)
Project Year: Apr 2004 - Mar 2006    Investigator(s): Mikiro Nakashima, Koyo Nishida
Japan Society for the Promotion of Science: Grant-in-Aid for Scientific Research (C)
Project Year: Apr 2003 - Mar 2006    Investigator(s): Mikiro Nakashima, Hitoshi Sasaki
Study on practical science based on pharmacy practice and medical communication
The Other Research Programs
Project Year: 2005   
Japan Society for the Promotion of Science: Grant-in-Aid for Scientific Research (C)
Project Year: Apr 2002 - Mar 2004    Investigator(s): Mikiro Nakashima, Koyo Nishida
Japan Society for the Promotion of Science: Grant-in-Aid for Scientific Research (C)
Project Year: Apr 2001 - Mar 2003    Investigator(s): Mikiro Nakashima, Junzo Nakamura
Japan Society for the Promotion of Science: Grant-in-Aid for Scientific Research (C)
Project Year: Apr 1997 - Mar 2000    Investigator(s): Mikiro Nakashima, Hitoshi Sasaki
Japan Society for the Promotion of Science: Grant-in-Aid for Encouragement of Scientists (A)
Project Year: Apr 1995 - Mar 1996    Investigator(s): Mikiro Nakashima
Japan Society for the Promotion of Science: Grant-in-Aid for Encouragement of Scientists (A)
Project Year: Apr 1994 - Mar 1995    Investigator(s): Mikiro Nakashima
Study on basic and clinical pharmaceutical sciences for rational use of generic drugs
The Other Research Programs
Project Year: 1984   
Development of methodology for evaluation of efficacy and adverse effect of medicine
The Other Research Programs
Project Year: 1984