MISC

2010年8月

Relationship between adipokines and periodontitis

Japanese Dental Science Review
  • Reiko Furugen
  • ,
  • Hideaki Hayashida
  • ,
  • Masayasu Kitamura
  • ,
  • Toshiyuki Saito

46
2
開始ページ
159
終了ページ
164
記述言語
英語
掲載種別
書評論文,書評,文献紹介等
DOI
10.1016/j.jdsr.2010.01.001

Obesity is associated with an increased risk for developing characteristic features of metabolic syndrome, including hypertension, type 2 diabetes, and dyslipidemia. Interestingly, chronic exposure to periodontal pathogens' endotoxin and increased cytokine production have been proposed to enhance the risk for causing type 2 diabetes and cardiovascular complications. Obesity has also recently been reported to be associated with periodontitis. Obesity induces macrophage accumulation in adipose tissue, promotes chronic low-grade inflammation, and increases adipokines derived from adipocytes. In this review, we summarize recent advances in understanding the roles of adipokines in chronic inflammatory states such as periodontitis and focus primarily on adiponectin, leptin, and resistin. Understanding the role of adipokines may help elucidate relationships among periodontitis, obesity, type 2 diabetes, and cardiovascular diseases. © 2010 Japanese Association for Dental Science.

リンク情報
DOI
https://doi.org/10.1016/j.jdsr.2010.01.001
CiNii Articles
http://ci.nii.ac.jp/naid/10026519082
ID情報
  • DOI : 10.1016/j.jdsr.2010.01.001
  • ISSN : 1882-7616
  • CiNii Articles ID : 10026519082
  • SCOPUS ID : 77955058046

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