小林直彦 (Naohiko Kobayashi) - マイポータル - researchmap

基本情報

所属: 獨協医科大学医学部医学科循環器内科助教授・准教授

学位: 医学博士

J-GLOBAL ID: 200901091045919106
researchmap会員ID: 1000166959

研究キーワード

3

研究分野

2

学歴

4

委員歴

10

受賞

4

MISC

56

Betaxolol stimulates eNOS production associated with LOX-1 and VEGF in Dahl salt-sensitive rats

N Kobayashi, K Yoshida, S Mita, T Honda, K Hara, S Nakano, Y Tsubokou, H Matsuoka

JOURNAL OF HYPERTENSION 22(7) 1397-1402 2004年7月
左室心筋における中等度低酸素による誘導型NO合成酵素（iNOS）の発現．

麻酔 53: 23-28. 2004年
Comparison of once-daily nifedipine controlled-release with twice-daily nifedipine retard in the treatment of essential hypertension.

Br J Clin Pharmacol 57: 632-639 2004年
Nicorandil protects against lethal ischemic arrhythmias and up-regulates endothelial nitric oxide synthase expression and sulfonylurea receptor 2 mRNA in conscious rats with acute myocardial infarction.

Cardiovasc Drugs Ther 18: 13-22 2004年
Celiprolol activates eNOS through the PI3K-Akt pathway and inhibits VCAM-1 Via NF-κB induced by oxidative stress

Hypertension 42(5) 1004-1013 2003年11月
Chronic administration of adrenomedullin attenuates transition from left ventricular hypertrophy to heart failure in rats

T Nishikimi, F Yoshihara, S Horinaka, N Kobayashi, Y Mori, K Tadokoro, K Akimoto, N Minamino, K Kangawa, H Matsuoka

HYPERTENSION 42(5) 1034-1041 2003年11月
Celiprolol activates eNOS through the PI3K-Akt pathway and inhibits VCAM-1 via NF-kappa B induced by oxidative stress

N Kobayashi, S Mita, K Yoshida, T Honda, T Kobayashi, K Hara, S Nakano, Y Tsubokou, H Matsuoka

HYPERTENSION 42(5) 1004-1013 2003年11月
Chronic administration of adrenomedullin attenuates transition from left ventricular hypertrophy to heart failure in rats

T Nishikimi, F Yoshihara, S Horinaka, N Kobayashi, Y Mori, K Tadokoro, K Akimoto, N Minamino, K Kangawa, H Matsuoka

HYPERTENSION 42(5) 1034-1041 2003年11月
Expression of inducible nitric oxide synthase, left ventricular function and remodeling in Dahl salt-sensitive hypertensive rats

S Horinaka, N Kobayashi, Y Mori, H Yagi, M Onoda, H Matsuoka

INTERNATIONAL JOURNAL OF CARDIOLOGY 91(1) 25-35 2003年9月
Expression of inducible nitric oxide synthase, left ventricular function and remodeling in Dahl salt-sensitive hypertensive rats

S Horinaka, N Kobayashi, Y Mori, H Yagi, M Onoda, H Matsuoka

INTERNATIONAL JOURNAL OF CARDIOLOGY 91(1) 25-35 2003年9月
Angiotensin Ⅱand oxidative stress in Dahl salt-sensitive rat with heart failure.

Hypertension 40(6) 834-839 2002年12月
Angiotensin II and oxidative stress in Dahl salt-sensitive rat with heart failure

A Tojo, ML Onozato, N Kobayashi, A Goto, H Matsuoka, T Fujita

HYPERTENSION 40(6) 834-839 2002年12月
Long-term adrenomedullin infusion improves survival in malignant hypertensive rats

Y Mori, T Nishikimi, N Kobayashi, H Ono, K Kangawa, H Matsuoka

HYPERTENSION 40(1) 107-113 2002年7月
Long-term adrenomedullin infusion improves survival in malignant hypertensive rats

Y Mori, T Nishikimi, N Kobayashi, H Ono, K Kangawa, H Matsuoka

HYPERTENSION 40(1) 107-113 2002年7月
Aminoguanidine inhibits mitogen-activated protein kinase and improves cardiac performance and cardiovascular remodeling in failing heats of salf-sensitive hypertensive rats.

J Hypertens 20, 2475-2485 2002年
Renoprotective effect of chronic adrenomedullin rnfusion in Dahl salt-sensitive rats.

Hypertension 39;1077-1082 2002年
Betaxolol inhibits extracellular signal-regulated kinase and p70S6 kinase activities and gene expressions of platelet-derived growth factor A-chain and transforming growth factor-β1 in Dahl salt-sensitive hypertensive rats.

Hypertens Res 25;211-219 2002年
Celiprolol inhibits mitogen-activated protein kinase and endothelin-1 and transforming growth factor-β1 gene in rats.

Eur J Pharmacol 457;85-93 2002年
Critical role of Rho-kinase pathway for cardiac performance and remodeling in failing rat hearts.

Cardiovasc Res 55;757-767 2002年
Involvement of Rho-kinase pathway for angiotensin Ⅱ-induced plasminogen activator inhibitor-1 gene expression and cardiovascular remodeling in hypertensive rats.

J Pharmacel Exp Ther 301;459-466 2002年

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所属学協会

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共同研究・競争的資金等の研究課題

11