AKIYAMA Takahiko

J-GLOBAL         Last updated: Nov 14, 2018 at 16:13
AKIYAMA Takahiko
Gakushuin University
Faculty of Science, Department of Chemistry

Research Interests


Research Areas


Academic & Professional Experience

Apr 1997
Professor, Department of Chemistry, Faculty of Science, Gakushuin University
Apr 1994
Mar 1997
Associate Professor, Department of Chemistry, Gakushuin University
Jul 1988
Mar 1994
Assistant Professor, Department of Resources Chemistry, Faculty of Engineering, Ehime University
Apr 1992
Mar 1993
Visiting Scholar, Department of Chemistry, Stanford University
Apr 1985
Jun 1988
Research Chemist, Shionogi Research Laboratories, Shionogi & Co., Ltd.


Graduate School, Division of Science, The University of Tokyo
Faculty of Science, The University of Tokyo

Awards & Honors

Feb 2018
Synthetic Organic Chemistry Award, Japan, The Society of Synthetic Organic Chemistry, Japan
Aug 2016
Arthur C. Cope Scholar Award, American Chemical Society
Mar 2016
Humboldt Research Award, Humboldt Foundation
Nov 2012
Nagoya Silver Medal, Banyu Life Science Foundation International
Mar 2009
The Chemical Society of Japan Award for Creative Work for 2009, The Chemical Society of Japan
Feb 2009
SSOCJ (The Society of Synthetic Organic Chemistry, Japan) Daiichi-Sankyo Award for Medicinal Organic Chemistry 2009, The Society of Synthetic Organic Chemistry, Japan
Feb 1997
Takeda Pharmaceutical Company Award in Synthetic Organic Chemistry, Japan, The Society of Synthetic Organic Chemistry, Japan

Published Papers

Kodai Saito, Taishi Umi, Takayuki Yamada, Takuya Suga, Takahiko Akiyama
Org. Biomol. Chem.      2017   [Refereed]
Keiji Mori, Tsubasa Itakura, Takahiko Akiyama
Angewandte Chemie International Edition   55(38) 11642   Sep 2016   [Refereed]


Masamichi Miyagawa, Kensuke Takashima, Takahiko Akiyama
Synlett      May 2018
Copyright © 2018, Georg Thieme Verlag. All rights reserved. An enantioselective transfer hydrogenation reaction of alkynyl ketimine bearing a trifluoromethyl group was accomplished. Chemoselective reduction of ketimine was achieved by the combined...
Keiji Mori, Ryo Isogai, Yuto Kamei, Masahiro Yamanaka, Takahiko Akiyama
Journal of the American Chemical Society      Mar 2018
© 2018 American Chemical Society. Described herein is a chiral magnesium bisphosphate catalyzed asymmetric double C(sp 3 )-H bond functionalization triggered by a sequential hydride shift/cyclization process. This reaction consists of stereoselect...
Masamichi Miyagawa, Takahiko Akiyama
Chemistry Letters   47 78-81   Jan 2018
© 2018 The Chemical Society of Japan. The Tishchenko reaction is one of the useful methods for ester synthesis. Intra- and intermolecular Tishchenko reactions using metallic zinc are described. A practical Tishchenko reaction using metallic zinc w...
Keiji Mori, Keiji Mori, Hiroki Kishi, Takahiko Akiyama
Synthesis (Germany)   49 365-370   Jan 2017
© 2017 Georg Thieme Verlag Stuttgart, New York. We report herein a highly efficient kinetic resolution of PHANOL by chiral phosphoric acid catalyzed asymmetric acylation. PHANOL enantiomers were well differentiated by the chiral environment of chi...
Keiji Mori, Manato Kobayashi, Tsubasa Itakura, Takahiko Akiyama
Advanced Synthesis and Catalysis   357 35-40   Nov 2015
© 2015 Wiley-VCH Verlag GmbH&Co. KGaA. We report herein a highly enantioselective synthesis of multisubstituted biaryl chlorides/iodides by sequential halogenation reactions (desymmetrization/ kinetic resolution sequence). The selectivity of biary...

Research Grants & Projects

JSPS: A Grant-in-Aid for Scienti- fic Research
Project Year: Apr 2016 - Mar 2018    Investigator(s): AKIYAMA Takahiko
JSPS: a Grant-in-Aid for Scienti- fic Research (B)
Project Year: Apr 2014 - Mar 2017    Investigator(s): AKIYAMA Takahiko
Development of Controlling System for Chiral Phosphoric Acid
MEXT: a Grant-in-Aid for Scientific Research on Innovative Areas
Project Year: Sep 2011 - Mar 2016    Investigator(s): AKIYAMA Takahiko
Asymmetric Synthesis by Organic Catalysis
Grant-in-Aid for Scientific Research
Project Year: 2002   
Development of Synthetic Reactions in Aqueous Media
Development of new synthetic reactions employing silicon
Development of movel asymmetric reactions