Oka Kotaro

Profile Information

Affiliation: Professor, School of Frontier Engineering, Kitasato University

Degree: 工学(慶應義塾)
工学(慶應義塾)
工学(Keio University)
工学(Keio University)

Researcher number: 10276412
J-GLOBAL ID: 200901013363023382
researchmap Member ID: 1000197128

External link: http://www.bpni.bio.keio.ac.jp

Research Interests

Biophysics, Neuroscience, Systems Biology

Research Areas

Research History

Apr, 2005 - Present

慶應義塾大学理工学部生命情報学科、教授
Apr, 1998 - Present

慶應義塾大学理工学部システムデザイン工学科,大学院理工学研究科生体医工学専攻 ,助教授
Apr, 2002 - Mar, 2005

慶應義塾大学理工学部生命情報学科、助教授
Apr, 1997 - Mar, 1998

兼慶應義塾大学理工学部機械工学科 ,教室幹事
Apr, 1996 - Mar, 1998

慶應義塾大学理工学部システムデザイン工学科 ,専任講師
Apr, 1995 - Mar, 1996

慶應義塾大学理工学部機械工学科 ,専任講師
Apr, 1988 - Mar, 1995

（株）富士通研究所入社機能有機材料研究部 ,技師補研究員
Oct, 1991 - Oct, 1992

米国国立衛生研究所（ＮＩＨ）国立精神障害・卒中研究所（ＮＩＮＤＳ） ,客員研究員
Jun, 1992 - Sep, 1992

米国マサチューセッツ州ウッズホール海洋生物学研究所 ,research associate

Education

Committee Memberships

Dec, 1997 - Present

幹事, 日本機械学会「生物に学ぶメカニカルテクノロジー」委託出版分科会
Dec, 1997 - Present

幹事, 日本機械学会「生物に学ぶメカニカルテクノロジー」委託出版分科会
Nov, 1997 - Present

実行委員, 第11回日本ＭＥ学会秋季大会（1997年）
Nov, 1997 - Present

実行委員, 日本機械学会 1999年年次大会
Nov, 1997 - Present

実行委員, 第11回日本ＭＥ学会秋季大会（1997年）
Nov, 1997 - Present

実行委員, 日本機械学会 1999年年次大会
Apr, 1995 - Sep, 1997

研究推進委員, 新技術事業団河内微小流動プロジェクト
Apr, 1995 - Sep, 1997

研究推進委員, 新技術事業団河内微小流動プロジェクト
Sep, 1996 - Mar, 1997

特別研究員, 農林水産省食品総合研究所
Sep, 1996 - Mar, 1997

特別研究員, 農林水産省食品総合研究所
Aug, 1995 - Mar, 1996

共同利用研究員, 放射線医学研究所（第３研究グループ）
Aug, 1995 - Mar, 1996

共同利用研究員, 放射線医学研究所（第３研究グループ）

Papers

231

Calcium-induced upregulation of energy metabolism heats neurons during neural activity

Jayang Wu, Yutaka Shindo, Kohji Hotta, Cong Quang Vu, Kai Lu, Tetsuichi Wazawa, Takeharu Nagai, Kotaro Oka

Biochemical and Biophysical Research Communications, 149799-149799, Mar, 2024
Distribution changes of non-self-test cells and self-tunic cells surrounding the outer body during Ciona metamorphosis.

Nozomu M Totsuka, Satoshi Kuwana, Satoshi Sawai, Kotaro Oka, Yasunori Sasakura, Kohji Hotta

Developmental dynamics : an official publication of the American Association of Anatomists, Jun 21, 2023
Effect of the side chain composition of mixed-charge polymers on pH-selective cell–membrane interactions

Yubuki Nakamura, Marina Nasu, Yutaka Shindo, Kotaro Oka, Daniel Citterio, Yuki Hiruta

Polymer Journal, Mar 29, 2023
Multimodal factor evaluation system for organismal transparency by hyperspectral imaging.

Takumi T Shito, Kotaro Oka, Kohji Hotta

PloS one, 18(10) e0292524, 2023
Transitions of motor neuron activities during Ciona development.

Madoka K Utsumi, Kotaro Oka, Kohji Hotta

Frontiers in cell and developmental biology, 11 1100887-1100887, 2023
Live imaging of apoptotic signaling flow using tunable combinatorial FRET-based bioprobes for cell population analysis of caspase cascades

Miho Suzuki, Yutaka Shindo, Ryu Yamanaka, Kotaro Oka

Scientific Reports, 12(1), Dec 7, 2022
Admp regulates tail bending by controlling ventral epidermal cell polarity via phosphorylated myosin localization in Ciona.

Yuki S Kogure, Hiromochi Muraoka, Wataru C Koizumi, Raphaël Gelin-Alessi, Benoit Godard, Kotaro Oka, Carl-Philipp Heisenberg, Kohji Hotta

Development (Cambridge, England), 149(21), Nov 1, 2022
MiniSOG2-mediated Specific Photoablation of Motor Neurons in Ascidian Embryos.

Madoka K Utsumi, Taichi Akahoshi, Kotaro Oka, Kohji Hotta

Bio-protocol, 12(20), Oct 20, 2022
Organelle-selective near-infrared fluorescent probes for intracellular microenvironment labeling

Atanas Kurutos, Yutaka Shindo, Yuki Hiruta, Kotaro Oka, Daniel Citterio

Dyes and Pigments, 204 110424-110424, Aug, 2022
Developmental Table and Three-Dimensional Embryological Image Resource of the Ascidian Ascidiella aspersa

Haruka M. Funakoshi, Takumi T. Shito, Kotaro Oka, Kohji Hotta

Frontiers in Cell and Developmental Biology, 9, Dec 17, 2021
Mechanical stimulus-evoked signal transduction between keratinocytes and sensory neurons via extracellular ATP

Shindo Y, Fujita K, Tanaka M, Fujio H, Hotta K, Oka K

Biochemical and Biophysical Research Communications, 582 131-136, Dec 10, 2021
A single motor neuron determines the rhythm of early motor behavior in

Akahoshi, Taichi, Utsumi, Madoka K, Oonuma, Kouhei, Murakami, Makoto, Horie, Takeo, Kusakabe, Takehiro G, Oka, Kotaro, Hotta, Kohji

Science advances, 7(50) eabl6053, Dec, 2021 Peer-reviewed
Spatiotemporal dynamics of single cell stiffness in the early developing ascidian chordate embryo

Yuki Fujii, Wataru C. Koizumi, Taichi Imai, Megumi Yokobori, Tomohiro Matsuo, Kotaro Oka, Kohji Hotta, Takaharu Okajima

Communications Biology, 4(1), Dec, 2021
Peripheral-neuron-like properties of differentiated human dental pulp stem cells (hDPSCs)

Yuki Arimura, Yutaka Shindo, Ryu Yamanaka, Mai Mochizuki, Kohji Hotta, Taka Nakahara, Etsuro Ito, Tohru Yoshioka, Kotaro Oka

PLOS ONE, 16(5) e0251356-e0251356, May 6, 2021
Small molecule-based alkaline-earth metal ion fluorescent probes for imaging intracellular and intercellular multiple signals

Hiruta Y, Shindo Y, Oka K, Citterio D

Chemistry Letters, 50(5) 870-887, May, 2021
High responsiveness of auditory neurons to specific combination of acoustic features in female songbirds.

Masahiro Inda, Kohji Hotta, Kotaro Oka

The European journal of neuroscience, 53(5) 1412-1427, Mar, 2021
Two-Round Ca2+ transient in papillae by mechanical stimulation induces metamorphosis in the ascidian Ciona intestinalis type A.

Maiki K Wakai, Mitsuru J Nakamura, Satoshi Sawai, Kohji Hotta, Kotaro Oka

Proceedings. Biological sciences, 288(1945) 20203207-20203207, Feb 24, 2021
Activation of the orbitofrontal cortex by both meditation and exercise: A near-infrared spectroscopy study

Miyashiro S, Yamada Y, Muta T, Ishikawa H, Abe T, Hori M, Oka K, Koshikawa F, Ito E

PLoS ONE, 16(2 February) e0247685, Feb, 2021
Development of an online platform that can simulate the biological course of field training

SHITO Takumi, FUNAKOSHI Haruka, TOTSUKA Nozomu, KOGURE Yuki, FURUKAWA Ryohei, KURAISHI Ritsu, OKA Kotaro, HOTTA Kohji

Proceedings of the Annual Meeting of Japan Society for Science Education, 45 621-624, 2021
Construction and introduction of interactive WEB teaching materials that enable simulated experience of microscopic observation for biological education

FUNAKOSHI Haruka, SHITO Takumi, OKA Kotaro, FURUKAWA Ryohei, KURAISHI Ritsu, HOTTA Kohji

Proceedings of the Annual Meeting of Japan Society for Science Education, 45 625-628, 2021

Misc.

107

Development of an online platform that can simulate the biological course of field training

紫藤拓巳, 船越悠, 戸塚望, 小暮悠暉, 古川亮平, 倉石立, 岡浩太郎, 堀田耕司

日本科学教育学会年会論文集(Web), 45th, 2021
蛍光イメージングによる神経細胞内マグネシウムイオン動態の解析

新藤豊, 山中龍, 鈴木孝治, 岡浩太郎

バイオイメージング, 25(1) 32-37, 2016
ラマン分光イメージングによる非標識条件下でのホヤ胚の細胞分化識別

HOTTA KOHJI

比較内分泌学, 42(158) 52-53, Jan 1, 2016
How Variety of Time Scales in Memory could Caenorhabditis elegans, a Simple and Compact Neural Circuit Organism, Form?

Hisashi Shidara, Kotaro Oka

Memory Consolidation, 1-18, 2015
コフィリンロッド形成および消失の速度論的解析

小林孝彦, 堀田耕司, 岡浩太郎

バイオイメージング, 20(2) 153-154, Aug 10, 2011
ITOガラス電極の電流刺激による培養海馬神経細胞間のカルシウム伝播

棚元亮, 庭野真理子, 堀田耕司, 三木則尚, 松本佳宣, 岡浩太郎

バイオイメージング, 20(2) 171-172, Aug 10, 2011
GABA刺激による神経細胞マグネシウム動員

山中龍, 新藤豊, 堀田耕司, 鈴木孝治, 岡浩太郎

バイオイメージング, 20(2) 165-166, Aug 10, 2011
さえずりに対するメスキンカチョウ海馬体神経活動のpHイメージング法を用いた解析

高延岳史, 高山文博, 堀田耕司, 岡浩太郎

バイオイメージング, 20(2) 169-170, Aug 10, 2011
Kinetic analysis of cofilin rods formation in local cell regions

Takahiko Kobayashi, Kohji Hotta, Kotaro Oka

NEUROSCIENCE RESEARCH, 71 E117-E117, 2011
GABA-induced magnesium increase in rat hippocampal neurons

Ryu Yamanaka, Yutaka Shindo, Kohji Hotta, Koji Suzuki, Kotaro Oka

NEUROSCIENCE RESEARCH, 71 E212-E212, 2011
Measurements of local magnesium concentration changes in neurons

Yutaka Shindo, Tomohiko Fujii, Ryu Yamanaka, Kohji Hotta, Koji Suzuki, Kotaro Oka

NEUROSCIENCE RESEARCH, 71 E309-E309, 2011
Ca imaging of hippocampal neurons on ITO glass electrodes

Ryo Tanamoto, Kohji Hotta, Kotaro Oka

NEUROSCIENCE RESEARCH, 71 E309-E310, 2011
Intactイカの色素胞活動解析によるパターン形成メカニズムの解明

鈴木真美子, 木村哲也, 小川宏人, 堀田耕司, 岡浩太郎

バイオイメージング, 19(2) 114-115, Aug 6, 2010
Dendritic Ca2+-accumulation pattern and direction-dependent plasticity induced by repetitive stimuli in the identified sensory interneurons

Hiroto Ogawa, Kotaro Oka

NEUROSCIENCE RESEARCH, 68 E278-E278, 2010
IN VIVO pH RESPONSES EVOKED BY ELECTRICAL AND SOUND STIMULATION IN HIPPOCAMPAL FORMATION OF FEMALE ZEBRA FINCH

Fumihiro Takayama, Toshimobu Shimoi, Takuro Sakuratani, Akira Fujimura, Mai Iwasaki, Kohji Hotta, Kotaro Oka

JOURNAL OF PHYSIOLOGICAL SCIENCES, 59 429-429, 2009
ROLES OF NITRIC OXIDE IN SHORT-TERM MEMORY FORMATION IN EARTHWORMS

Takehiko Mochida, Kosuke Watanabe, Mamiko Suzuki, Toshinobu Shimoi, Hiroto Ogawa, Koji Hotta, Kotaro Oka

JOURNAL OF PHYSIOLOGICAL SCIENCES, 59 178-178, 2009
Is the novel structure in the tunic-fin of the ascidian larvae the peripheral neuronal cells?

Hiroshi Terakubo, Yoko Nakajima, Takeo Horie, Yasunori Sasakura, Kohji Hotta, Kotaro Oka

GENES & GENETIC SYSTEMS, 83(6) 502-502, Dec, 2008
In vivo calcium imaging of mushroom body calyx in the cricket before and after odor-taste conditioning

Hiroto Ogawa, Kotaro Oka

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 151(4) 455-455, Dec, 2008
音刺激により誘発されるメスキンカチョウ海馬体神経活動のpHイメージング

高山文博, 櫻谷卓朗, 藤村彬, 岩崎麻衣, 堀田耕司, 岡浩太郎

バイオイメージング, 17(2) 176-177, Oct 30, 2008
最初期遺伝子Arcを用いたcatFISH法によるメスキンカチョウ神経活動の可視化

藤村彬, 岩崎麻衣, 高山文博, 堀田耕司, 岡浩太郎

バイオイメージング, 17(2) 232-233, Oct 30, 2008

Books and Other Publications

Development of Near-Infrared Fluorescent Mg²⁺ Probe and Application to Multicolor Imaging of Intracellular Signals

Shindo Y, Ikeda Y, Hiruta Y, Citterio D, Oka K

Methods in Molecular Biology, 2021
生体の科学

岡浩太郎 (Role: Contributor, 446-447)

医学書院, Oct 15, 2017
社会適応発現機構と機能障害

岡浩太郎 (Role: Joint author, 121-160)

オーム社, 2010
身近な動物を使った実験2

北村美一郎, 岡浩太郎 (Role: Joint author, 65-82)

三共出版, 2009
昆虫ミメティックス

小川宏人, 岡浩太郎 (Role: Joint author, 650-656)

エヌ・ティー・エス, 2008
教養の生命学III

岡浩太郎 (Role: Joint author)

慶應義塾大学出版会, 2007
Methods Mol Biol.

Kitamura Y, Kobayashi H, Tanishita K, Oka K

2004
生命の科学への招待

岡浩太郎

三共出版, Apr 15, 2003
メカノクリーチャ -生物から学ぶデザインテクノロジー-

岡浩太郎

コロナ社, Apr 10, 2003
研究室紹介「慶應義塾大学理工学部生命情報学科」

岡浩太郎

2003

Presentations

314

培養神経回路網における機能的結合の形成と維持

井出龍斗, 岡浩太郎, 堀田耕司, 新藤豊

第43回日本神経科学大会, Jul 30, 2020
The properties of neural activities by acoustic factors in higher auditory region to sound stimuli in awake and anesthetized finches.

A. Yoshida, M. Inda, K. Hotta, K. Oka

Neuroscience 2019, Oct 22, 2019
Region specific timescale dependency of auditory neural activity to song stimulus in avian brain.

M. Inda, A. Yoshida, K. Hotta, K. Oka

Neuroscience 2019, Oct 15, 2019
Whole ganglion mapping for various mechanosensation in the leech nervous system using voltage-sensitive dye imaging.

Y. Tomita, K. Oka, D. A. Wagenaar

Neuroscience 2019, Oct, 2019
Quantitative analysis of cell cycle progression within heterogeneous cell population using information theory.

The 6th International Symposium on Bioimaging, Sep 22, 2019
Simultaneous visualization of intracellular energy substrates by using dual FRET imaging.

Shindo Y, Iizumi M, Yamanaka R, Hotta K, Oka K

The 6th International Symposium on Bioimaging, Sep 22, 2019
Mg ion as a novel candidate for second messenger.

Oka K, Yamanaka R, Shindo R

The 6th International Symposium on Bioimaging, Sep 22, 2019 Invited
慢性痛の心理生物学的基盤

越川房子, 牟田季純, 岡浩太郎, 加藤総夫, 仙波恵美子, 伊藤悦郎

日本心理学会第83回大会, Sep 11, 2019 Invited
線虫早期順応での感覚および介在神経細胞間関係のイメージングによる解明

芦田慶太, 設樂久志, 堀田耕司, 岡浩太郎

第42回日本神経科学大会, Jul 25, 2019
鳥類高聴覚領域における時間スケールに依存した神経活動の性質について

院田雅裕, 吉田彩乃, 堀田耕司, 岡浩太郎

第42回日本神経科学大会, Jul 25, 2019
鳥類高次聴覚領域における音声刺激に対する神経応答特性

吉田彩乃, 院田雅裕, 堀田耕司, 岡浩太郎

第42回日本神経科学大会, Jul 25, 2019
Mg²⁺ as a second messenger in early developmental stages of neurons

Oka K

IV International Magnesium Symposium “MAGNESIUM IN HEALTH AND DISEASE”, Mar 22, 2019 Invited
Structural changes of songs in adult zebra finch by chronical application of thyroid hormone.

Iwanaga M, Hotta K, Oka K

Neuroscience 2018, Nov 6, 2018
Identification of brain regions by hyperspectral imaging without staining.

Inoue S, Hotta K, Oka K

Neuroscience 2018, Nov 6, 2018
3D brain structure in zebra finch by CUBIC and voronoi tessellation.

Endo M, Inoue S, Inda M, Hotta K, Oka K

Neuroscience 2018, Nov 6, 2018
Characterization of neural cells derived from human dental pulp stem cells.

Ariumura Y, Kikuchi T, Yamanaka R, Shido Y, Hotta K, Mochizuki M, Oka K

Neuroscience 2018, Nov 5, 2018
Serotonin modulates neural activity of RID interneuron and the behavior in Caenorhabditis elegans.

Mori H, Ashida K, Shidara H, Hotta K, Oka K

Neuroscience 2018, Nov 4, 2018
Temporal tuning system for acoustic factors in female avian auditory cortex.

Inda M, Hotta K, Oka K

Neuroscience 2018, Nov 4, 2018
Quantitative analysis of cell cycle progression within heterogeneous cell population using information theory.

Yamanaka R, Oka K

The 6th International Symposium on Bioimaging, Sep 22, 2018
細胞内マグネシウムイメージング

新藤豊, 山中龍, 鈴木孝治, 堀田耕司, 岡浩太郎

第27回日本バイオイメージング学会学術集会, Sep 4, 2018

Teaching Experience

Professional Memberships

日本バイオイメージング学会

Research Projects

ヒト末梢神経系のin vitro再構成系の構築による痛み緩和メカニズムの解明

Grant-in-Aid for Scientific Research, Grant-in-Aid for Challenging Research (Exploratory), MEXT,JSPS, Jul, 2021 - Mar, 2024

岡浩太郎
Psycho- Biological Basis of Pain

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2022

Koshikawa Fusako
Detection of singularity neurons during neural network formation

Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas, MEXT,JSPS, Apr, 2019 - Mar, 2021

岡浩太郎
Bio-imaging without targets

Grant-in-Aid for Scientific Research, Grant-in-Aid for Challenging Research (Exploratory), MEXT,JSPS, Jun, 2017 - Mar, 2019

岡浩太郎
Is Mg ion a novel second messenger for regulating energy metabolism?

Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), MEXT,JSPS, Apr, 2016 - Mar, 2019

岡浩太郎
Comprehensive neuroanatomy by using non-staining imaging and informatics

Grant-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, MEXT,JSPS, Apr, 2015 - Mar, 2017

岡浩太郎
Studies on Ciona notochord tubulogenesis by chemical biology approach

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2015

IMOTO Masaya, TASHIRO Etsu, HOTTA Kouji, OKA Koutaro
Comprehensive understanding of intracellular Mg2+ function in neurons with fluorescent imaging

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2015

OKA KOTARO, SUZUKI Koji
Quantitative understanding for neural plasticity of C. elegans with newly developed micro-fluidic device

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2014

OKA KOTARO
蛍光イメージング法による鳥海馬神経回路解析

科学研究費助成事業, 新学術領域研究(研究領域提案型), 日本学術振興会, 2010 - 2011

岡浩太郎
Comprehensive approaches for investigating the neural network dynamics in C. elegans

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, 2010 - 2011

OKA Kotaro
Systems biological analysis of signal transduction in growth cones

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2009 - 2011

OKA Kotaro, FUNAHASHI Akira, HOTTA Kohji
生工連携的手法によるメス鳥のさえずり受容・識別メカニズムの定量的理解

科学研究費助成事業, 特定領域研究, 日本学術振興会, 2008 - 2009

岡浩太郎, 萩原将文, 伊澤栄一
神経細胞その場破壊技術による線虫神経回路のシステム生物学的解析

科学研究費助成事業, 萌芽研究, 日本学術振興会, 2007 - 2008

岡浩太郎
In vivo imaging of neuronal activity in insect during actual behavior

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2007 - 2008

OGAWA Hiroto, KOTARO Oka
Quantitative Imaging and Simulation Study for Analyzing Exocytosis in PC12 Cell

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2006 - 2007

OKA Kotaro, HOTTA Koji
キンカチョウさえずり識別メカニズムの神経回路レベルでの定量モデル構築

科学研究費助成事業, 特定領域研究, 日本学術振興会, 2006 - 2007

岡浩太郎, 萩原将文
線虫相互作用解析による集団行動突然変異体の抽出と行動データベースの作成

科学研究費助成事業, 萌芽研究, 日本学術振興会, 2004 - 2005

岡浩太郎
バイオマテリアルの生体内劣化とマクロファージ

科学研究費助成事業, 萌芽研究, 日本学術振興会, 2001 - 2002

小茂鳥潤, 山田健人, 岡浩太郎
A basic study on the development of metallic biomaterials

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2001 - 2002

KOMOTORI Jun, YAMADA Taketo, SUZUKI Tetsuya, OKA Kotaro, KATAHIRA Kazutoshi, NISHINO Souichiro

Social Activities

新技術事業団河内微小流動プロジェクト

Other

Apr, 1995 - Sep, 1997
農林水産省食品総合研究所

Other

Sep, 1996 - Mar, 1997
放射線医学研究所（第３研究グループ）

Other

Aug, 1995 - Mar, 1996

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Education

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Misc.

Books and Other Publications

Presentations

Teaching Experience

Professional Memberships

Research Projects

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