KUDO Nobuki

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Name
KUDO Nobuki
Nickname
nobuki
E-mail
kudoist.hokudai.ac.jp
URL
http://www.bio.ist.hokudai.ac.jp
Affiliation
Hokkaido University
Section
Graduate School of Information Science and Technology, Division of Bioengineering and Bioinformatics, Biomedical Systems Engineering
Job title
Associate Professor
Degree
MS and PhD degree in Biomedical Engineering in 1984 and 1987(Hokkaido University)

Research Areas

 
 

Academic & Professional Experience

 
1995
 - 
1997
 Research Associate,Faculty of Engineering, Hokkaido University
 
1997
 - 
2004
 Research Associate,Graduate School of Engineering, Hokkaido University
 
2004
 - 
2007
 Research Associate
 

Education

 
 
 - 
1984
Hokkaido University
 
 
 - 
1987
Hokkaido University
 
 
 - 
1982
Faculty of Engineering, Hokkaido University
 

Awards & Honors

 
2005
Best Presentation Award
 

Published Papers

 
Kudo N.
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control   64(1) 273-280   2016   [Refereed]
Miwa A, Kudo N.
2016 IEEE Ultrasonics Symposium Proceedings      2016   [Refereed]
Kudo N, Kadota T, Iijima Y.
2016 IEEE Ultrasonics Symposium Proceedings      2016   [Refereed]
Endo S, Kudo N, Yamaguchi S, Sumiyoshi K, Motegi H, Kobayashi H, Terasaka S, Houkin K.
Ultrasound in Medicine and Biology   41 2458-2465   2015   [Refereed]
Kudo N.
Ultrasound in Medicine and Biology   41 2071-2078   2015   [Refereed]

Misc

 
KUDO Nobuki
39(6) 567-568   Nov 2012
KUDO Nobuki
38(6) 623-624   Nov 2011
Obara Hiroki, Kudo Nobuki, Shimizu Koichi
IEICE technical report. Ultrasonics   111(88) 31-35   Jun 2011
Recently, there has been considerable interest in sonoporation, a technique to transduct drugs or genes into cells by ultrasound exposure. In typical studies of sonoporation using cultured cells, the cells and microbubbles are suspended in a cultu...
OKUYAMA Manabu, KUDO Nobuki, SHIMIZU Koichi
IEICE technical report. ME and bio cybernetics   111(84) 7-12   Jun 2011
Sonoporation is a promising technique that temporally increases membrane permeability by exposure of cells to ultrasound. We have been studying a sonoporation technique that uses short-pulsed ultrasound and reported that this exposure condition al...
LI Xin, KUDO Nobuki, SHIMIZU Koichi, KURIKI Shinya
2011(1) 71-76   Jan 2011
LI Xin, KUDO Nobuki, SHIMIZU Koichi, KURIKI Shinya
IEICE technical report. ME and bio cybernetics   110(399) 71-76   Jan 2011
A magnetic detection technique was devised to noninvasively detect the tip position of the nasal feeding tube that delivers liquid diet to the patient's stomach through a transnasal tube. We have designed an AC magnetic susceptibility measurement ...
KUDO Nobuki, SHIMIZU Koichi
IEICE technical report. ME and bio cybernetics   110(111) 13-16   Jun 2010
A suspension of microbubbles of about one micron in diameter is now widely used as a contrast agent for diagnostic ultrasound and as an enhancer for therapeutic ultrasound. In this study, five types of gas-encapsulated liposomes (bubble liposomes)...
Okada Kengo, Kudo Nobuki, Hassan Mariame A., Kondo Takashi, Yamamoto Katsuyuki
Proceedings of Symposium on Ultrasonic Electronics   (29) 419-420   Nov 2008
SUZUKI Ryosuke, SOSEKHA Ly, KUDO Nobuki, YAMAMOTO Katsuyuki
2007(36) 17-20   Jun 2007
KIBE Ryuta, KEK Khai Jun, KUDO Nobuki, YAMAMOTO Katsuyuki, YAMAMOTO Katsuyuki
IEICE technical report. ME and bio cybernetics   107(126) 13-16   Jun 2007
We have been developing a device for imaging muscle oxygenation using spatially resolved spectroscopy. To validate the measurement reliability of the device, we previously used tissue-mimicking liquid phantoms using red blood cells. However, valid...
SUZUKI Ryosuke, SOSEKHA Ly, KUDO Nobuki, YAMAMOTO Katsuyuki
IEICE technical report. ME and bio cybernetics   107(126) 17-20   Jun 2007
We have proposed a novel simple method for visualizing acoustic fields of diagnostic pulsed ultrasound without using a conventional Schlieren optical system. Based on the proposed method, we have developed an experimental system and have evaluated...
MIYAKAWA Takahiro, KEK Khai Jun, KUDO Nobuki, YAMAMOTO Katsuyuki
IEICE technical report. ME and bio cybernetics   106(127) 21-24   Jun 2006
Near-infrared spectroscopy (NIRS) is a useful technique for noninvasive and real-time measurement of muscle oxygenation. In this study, we constructed a continuous-wave NIRS (CWS) instrument with high temporal resolution. Using the instrument, we ...
MIYASHITA Hideki, KUDO Nobuki, YAMAMOTO Katsuyuki
IEICE technical report. ME and bio cybernetics   106(127) 5-8   Jun 2006
Previously, we proposed a novel simple Schlieren method that eliminates the use of complex optical system for visualizing acoustic fields of diagnostic pulsed ultrasound. Based on the proposed method, we developed an experiment system and evaluate...
YOKOYAMA Goya, OKADA Kengo, KUDO Nobuki, KAWAHARA Koichi, YAMAMOTO Katsuyuki
2005(7) 21-24   Jun 2005
IKEBUCHI Masayasu, OKADA Kengo, KUDO Nobuki, YAMAMOTO Katsuyuki
IEICE technical report. ME and bio cybernetics   105(122) 25-28   Jun 2005
Sonoporation is a technique that increases drug uptake of cells using ultrasound exposure. Recently, it has been shown that exposure of cells to pulsed ultrasound with microbubbles attached to the cells can improve efficiency of sonoporation; howe...
YOKOYAMA Goya, OKADA Kengo, KUDO Nobuki, KAWAHARA Koichi, YAMAMOTO Katsuyuki
IEICE technical report. ME and bio cybernetics   105(122) 21-24   Jun 2005
Recent study in human volunteers has shown that exposure to ultrasound during contrast echocardiography can cause premature ventricular contractions (PVCs). To elucidate its mechanism, we carried out experiments using cultivated cardiac myocytes a...
OUCHI Hiroyuki, KUDO Nobuki, YAMAMOTO Katsuyuki, SEKIMIZU Hidemasa
IEICE technical report. Ultrasonics   104(142) 9-12   Jun 2004
A new Schlieren method for visualizing an acoustic field of pulsed ultrasound was proposed, and a system was developed to evaluate the validity of the proposed method by visualizing an acoustic field of a focused ultrasound field of diagnostic fre...
YONEYAMA Satoko, KUDO Nobuki, YAMAMOTO Katsuyuki
IEICE technical report. ME and bio cybernetics   104(129) 5-8   Jun 2004
In recent years, many studies on muscle oxygenation measurement using near-infrared spectroscopy (NIRS) have been conducted. However, it is difficult to estimate the tissue metabolic kinetics from NIRS measurements because many factors are related...
MAEKAWA Kota, KUDO Nobuki, YAMAMOTO Katsuyuki
IEICE technical report. ME and bio cybernetics   104(129) 9-12   Jun 2004
Near-infrared spectroscopy (NIRS) is a useful technique for noninvasive and real-time measurement of tissue oxygenation. However, it is difficult to measure independently the oxygen concentrations of hemoglobin (Hb) and myoglobin (Mb) because the ...
OKADA Kengo, KUDO Nobuki, NIWA Koichi, WADA Shigeo, YAMAMOTO Katsuyuki
IEICE technical report. ME and bio cybernetics   103(133) 49-54   Jun 2003
Sonoporation is a technique that increases drag uptake of cells by ultrasound exposure. Ultrasound exposure of continuous wave has beens mainly used in this technique, and it is well known that existence of microbubbles around cells improves effic...
HIRAI Kosuke, MAEGAWA Kazuya, KOHATA Daisuke, KUDO Nobuki, YAMAMOTO Katsuyuki
17 341-344   Sep 2002
OGIHARA Makoto, KUDO Nobuki, YAMAMOTO Katsuyuki
IEICE technical report. ME and bio cybernetics   102(137) 13-16   Jun 2002
Recently, there has been further progress of the performance of diagnostic ultrasound equipment due to improvement of focusing techniques of ultrasound. This means that ultrasound intensity increases at a focal point, and therefore adverse effect ...
Nakamura Kazuaki, Kitama Masataka, Misawa Kenji, Arisawa Junji, Shao Jun, Kudo Nobuki, Yamamoto Katsuyuki
Memoirs of the Hokkaido Institute of Technology   30 261-266   Mar 2002
KUDO Nobuki, KURIBAYASHI Kaori, NATORI Michiya, MORIYASU Fuminori, YAMAMOTO Katsuyuki
The Transactions of the Institute of Electronics, Information and Communication Engineers. A   84(12) 1492-1499   Dec 2001
NAKAMURA Kazuaki, SHAO Jun, KUDO Nobuki, KITAMA Masataka, MISAWA Kenji, ARISAWA Junju, YAMAMOTO Katsuyuki
The Transactions of the Institute of Electronics, Information and Communication Engineers. A   84(12) 1525-1532   Dec 2001
NAKAMURA Kazuaki, SHAO Jun, KUDO Nobuki, KITAMA Masataka, MISAWA Kenji, ARISAWA Junji, YAMAMOTO Katsuyuki
IEICE technical report. ME and bio cybernetics   101(478) 87-92   Nov 2001
Ultrasound-modulated light has recently been utilized to improve a spatial resolution of optical imaging of biological tissues. This paper describes a method for detecting the ultrasound-modulated light by using variations in speckle patterns. A p...
Hirai Kousuke, Niwayama Masatsugu, Kohata Daisuke, Maekawa Kazuya, Kudo Nobuki, Hamaoka Takafumi, Katsumura Toshihito, Yamamoto Katsuyuki
IEICE technical report. ME and bio cybernetics   101(130) 1-8   Jun 2001
In recent years, continuous wave near-infrared spectroscopy (CW-NIRS) has been applied to in vivo reflectance imaging of muscle oxygenation. We previously developed a 200-channel imaging system that enables measurement of change in oxygenation and...
MIYAOKA Takehiro, FURUYA Junji, KUOD Nobuki, NIWA Kouichi, YAMAMOTO Katsuyuki
IEICE technical report. ME and bio cybernetics   101(130) 83-89   Jun 2001
Recently, it has been reported that activation of contrast agent gas bodies by ultrasound exposure can damage the cell membrane. To elucidate mechanisms of such cell damage, we improved an high-speed and high-magnification observation system using...
KUDO Nobuki, MIYAOKA Takehiro, OGIHARA Makoto, NATORI Michiya, YAMAMOTO Katsuyuki
28(3)    Apr 2001
Nakamura Kazuaki, Kitama Masataka, Misawa Kenji, Arisawa Junji, Sibayama Kaichiro, Shao Jun, Kudo Nobuki, Yamamoto Katsuyuki
Memoirs of the Hokkaido Institute of Technology   29 217-223   Mar 2001
KUDO Nobuki, ARITA Naoki, YAMAMOTO Katsuyuki
Symposium on ultrasonic electronics   (21) 347-348   Nov 2000
Yamamoto Katsuyuki, Niwayama Masatsugu, Kudo Nobuki
IEICE technical report.   100(287) 19-23   Sep 2000
In this talk, several new techniques for biomedical functional imaging using ultrasound and light will be presented. High-resolution imaging of tissues and blood flow in micro-vessels using a miniaturized ultrasound probe could be used for in vivo...
Kohata D., Niwayama M., Shao J., Kudo N., Hamaoka T., Katsumura T., Yamamoto K.
IEICE technical report. ME and bio cybernetics   100(163) 33-38   Jun 2000
In recent years, continuous wave near-infrared spectroscopy(CW-NIRS)has been applied to in vivo reflectance imaging of muscle oxygenation. However, conventional mapping systems do not have a sufficient measurement area at present. In this study, w...
Maegawa K., Niwayama M., Shao J., Kudo N., Yamamoto K.
IEICE technical report. ME and bio cybernetics   100(163) 39-44   Jun 2000
Spatially resolved spectroscopy(SRS)is a method for measuring the optical properties of a medium using spatial profiles of reflectance. This method is useful for quantitative measurement of tissue oxygenation with continuous wave light in real tim...
KUDO Nobuki, KURIBAYASHI Kaori, NATORI Michiya, MORIYASU Fuminori, YAMAMOTO Katsuyuki
27(4)    Apr 2000
KUDO Nobuki, KURIBAYASHI Kaori, YAMAMOTO Katsuyuki, NATORI Michiya, MORIYASU Fuminori
2000(1) 1057-1058   Mar 2000
KUDO Nobuki, SHIBAYAMA Kaichiro, SHAO Jun, YAMAMOTO Katsuyuki
1999(21) 37-42   Jun 1999
KURIBAYASHI Kaori, KUDO Nobuki, NATORI Michiya, YAMAMOTO Katsuyuki
26(4)    Apr 1999
YOSHIDA Makoto, KUDO Nobuki, YAMAMOTO Katsuyuki, MIKAMI Taisei, KITABATAKE Akira
1998(5) 75-80   Jun 1998
NIWAYAMA Masatsugu, SHIGA Toshikazu, LIN Ling, KUDO Nobuki, TAKAHASHI Makoto, YAMAMOTO Katsuyuki
1998(5) 81-88   Jun 1998
YOSHIDA Makoto, KUDO Nobuki, YAMAMOTO Katsuyuki, MIKAMI Taisei, KITABATAKE Akira
IEICE technical report. ME and bio cybernetics   98(135) 75-80   Jun 1998
In order to verify the contribution of a fibrous structure of biological tissue to ultrasound attenuation, we measured ultrasound attenuation coefficients of bovine muscular tissue in the frequency range of 10-40 MHz. Measurements were performed o...
NIWAYAMA Masatsugu, SHIGA Toshikazu, LIN Ling, KUDO Nobuki, TAKAHASHI Makoto, YAMAMOTO Katsuyuki
IEICE technical report. ME and bio cybernetics   98(135) 81-88   Jun 1998
The inhomogeneity of tissue structure greatly affects the sensitivity of tissue oxygenation measurement by reflectance NIRS. We have proposed a method for correcting the influence of a subcutaneous fat layer on muscle oxygenation measurement. In t...
KUDO N., YOSHIDA M., YAMAMOTO K., MIKAMI T., KITABATAKE A., ITO Y., KANDA H.
25(4)    Apr 1998
KUDO Nobuki, ZHANG Xu, YAMAMOTO Katsuyuki
25(3) 1-12   Mar 1998

Conference Activities & Talks

 
Obara Hiroki, Kudo Nobuki, Shimizu Koichi
Proceedings of Symposium on Ultrasonic Electronics   13 Nov 2012   
YAGI Satoshi, OKADA Kengo, KUDO Nobuki, SUZUKI Ryo, MARUYAMA Kazuo, YAMAMOTO Katsuyuki
15 Apr 2008   
SAKAGUCHI Katsuji, KUDO Nobuki, SUZUKI Ryo, MARUYAMA Kazuo, YAMAMOTO Katsuyuki
15 Apr 2008   
KUDO Nobuki, WATANABE Hiroshi, GOTO Shingo, OKADA Kengo, YAMAMOTO Katsuyuki
15 Apr 2008   
SUZUKI Ryosuke, KUDO Nobuki, YAMAMOTO Katsuyuki
15 Apr 2008   

Association Memberships

 
 

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(A))
Project Year: 2008 - 2010    Investigator(s): Nobuki KUDO
The final goal of this study was to develop a safe and efficient method for in vivo sonoporation that uses short-pulsed ultrasound in the presence of microbubbles adjacent to cells. A light microscopy system was developed for time-lapse observatio...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2007 - 2008    Investigator(s): Yamamoto KATSUYUKI
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2004 - 2006    Investigator(s): Katsuyuki YAMAMOTO
In this study, a small and lightweight instrument based on spatially resolved near-infrared spectroscopy (SR-NIRS) was developed for real-time imaging of muscle oxygenation. From the results of temporal and spatial analyses of muscle oxygenation d...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2004 - 2006    Investigator(s): Nobuki KUDO
Improvement of a high-speed observation systemTo improve spatial and temporal resolutions of high-speed observation, the use of an image intensifier with a high-speed camera and the use of an improved optical condenser for a short-arc flash lamp w...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2001 - 2003    Investigator(s): Katsuyuki YAMAMOTO
The purpose of this research project was to experimentally verify the causal relationships between measurements of near-infrared spectroscopy and the mechanisms of oxygen transport to the skeletal muscles. These relationships are essential for und...

Patents

 
第2645038号
1867287
第2937344号
EP-A1-000367116
EP-A1-000548048
EP-A1-000397056
第2968561号
US-A1-005095907
EP-A1-000404121
特許公開平5−31119
特許公開平5−192343
US-A1-00521310
特許公開平5−72071
EP-A2-000509800
US-A1-005357805
特許公開平5−306961
US-A1-005174294
特許公開平6−241885
特許公開平6−327691
US-A1-005465625
特許公開平8−191835
特許公開平8−252259
特許公開平8−294490
特許公開平8−299350
特許公開平8−308849
特許公開平9−522