2014年7月
Handling tRNA introns, archaeal way and eukaryotic way
FRONTIERS IN GENETICS
- 巻
- 5
- 号
- 開始ページ
- 213
- 終了ページ
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.3389/fgene.2014.00213
- 出版者・発行元
- FRONTIERS MEDIA SA
lntrons are found in various tRNA genes in all the three kingdoms of life. Especially, archaeal and eukaryotic genomes are good sources of tRNA introns that are removed by proteinaceous splicing machinery. Most intron-containing tRNA genes both in archaea and eukaryotes possess an intron at a so-called canonical position, one nucleotide 3' to their anticodon, while recent bioinformatics have revealed unusual types of tRNA introns and their derivatives especially in archaeal genomes. Gain and loss of tRNA introns during various stages of evolution are obvious both in archaea and eukaryotes from analyses of comparative genomics. The splicing of tRNA molecules has been studied extensively from biochemical and cell biological points of view, and such analyses of eukaryotic systems provided interesting findings in the past years. Here, I summarize recent progresses in the analyses of tRNA introns and the splicing process, and try to clarify new and old questions to be solved in the next stages.
- リンク情報
- ID情報
-
- DOI : 10.3389/fgene.2014.00213
- ISSN : 1664-8021
- Web of Science ID : WOS:000347218800001