Yoshihiko Maehara - My portal

Profile Information

Affiliation: Professor, Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers
: (Concurrent)名誉教授

Degree: (BLANK)(Kyushu University)

J-GLOBAL ID: 200901085030179289
researchmap Member ID: 1000201454

External link: http://www.congre.co.jp/kyushu-u/surg2/

Research Interests

Research Areas

Research History

Oct, 2015 - Present

Faculty of Medical Sciences, Kyushu University
Oct, 2014 - Present

第23期日本学術会議会員
Apr, 2012 - Present

センター長, 九州大学病院救命救急センター
Oct, 2002 - Present

教授, 九州大学大学院消化器・総合外科
1991 - 1997

九州大学医学部第二外科講師
1991 - 1997

Department of Surgery (]G0002[), Faculty of Medicine, Kyushu University, Assistant Professor
1997

- 九州大学大学院医学研究院消化器・総合外科(第二外科)
1997

- Department of Surgical Science, Graduate School of Medical Sciences, Kyushu University, Associate Professor
1989 - 1991

九州大学医学部第二外科助手
1989 - 1991

Department of Surgery (]G0002[), Faculty of Medicine, Kyushu University, Assistant Professor
1985 - 1989

九州大学医学部附属病院腫瘍センター助手・講師
1985 - 1989

Cancer Center, Faculty of Medicine, Kyushu University, Assistant Professor
1983 - 1985

九州大学生体防御医学研究助手
1983 - 1985

Medical Institute of Bioregulation, Kyushu University, Assistant Professor

Education

- 1983

Kyushu University
- 1983

Graduate School, Division of Medicine, Kyushu University
- 1977

School of Medicine, Kyushu University
- 1977

Faculty of Medicine, Kyushu University

Committee Memberships

Awards

1998

福岡県大学勤務医福岡県医師会長賞
1988

工藤学術財団褒賞

Papers

Indoleamine 2,3-dioxygenase 1 and programmed cell death-ligand 1 co-expression correlates with aggressive features in lung adenocarcinoma.

Yuka Kozuma, Kazuki Takada, Gouji Toyokawa, Kenichi Kohashi, Mototsugu Shimokawa, Fumihiko Hirai, Tetsuzo Tagawa, Tatsuro Okamoto, Yoshinao Oda, Yoshihiko Maehara

European journal of cancer (Oxford, England : 1990), 101 20-29, Sep, 2018
The state of cholesterol metabolism in the liver of patients with primary biliary cirrhosis: the role of MDR3 expression

Munechika Enjoji, Ryoko Yada, Tatsuya Fujino, Tsuyoshi Yoshimoto, Masayoshi Yada, Naohiko Harada, Nobito Higuchi, Masaki Kato, Motoyuki Kohjima, Akinobu Taketomi …

HEPATOLOGY INTERNATIONAL, 3(3) 490-496, Sep, 2009 Peer-reviewed
Prognostic significance of angiogenesis in gastrointestinal stromal tumor.

Masakazu Imamura, Hidetaka Yamamoto, Norimoto Nakamura, Yoshinao Oda, Takashi Yao, Yoshihiro Kakeji, Hideo Baba, Yoshihiko Maehara, Masazumi Tsuneyoshi

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 20(5) 529-37, May, 2007
Phase I study of S-1 and biweekly docetaxel combination chemotherapy for advanced and recurrent gastric cancer.

Ikuo Takahashi, Yasunori Emi, Yoshihiro Kakeji, Eriko Tokunaga, Shin Ushiro, Eiji Oki, Masayuki Watanabe, Hideo Baba, Yoshihiko Maehara

Oncology reports, 15(4) 849-54, Apr, 2006 Peer-reviewed

Misc.

ウロキナーゼ選択性腫瘍融解型センダイウイルスベクターを用いた悪性胸膜中皮腫に対する遺伝子治療(Development of gene therapy for malignant mesothelioma using BioKnife, an urokinase-targeted oncolytic Sendai virus)

諸富洋介, 米満吉和, 矢野篤次郎, 喜納宏昭, 吉田月久, 庄司文裕, 吉田久美, 上田泰次, 井上誠, 長谷川護 …

日本癌学会総会記事, 68回 89-89, Aug, 2009
DNA repair dysfunction in gastrointestinal tract cancers

Yoshihiko Maehara, Akinori Egashira, Eiji Oki, Yoshihiro Kakeji, Teruhisa Tsuzuki

CANCER SCIENCE, 99(3) 451-458, Mar, 2008
Hypermethylation of FHIT as a prognostic marker in nonsmall cell lung carcinoma

R Maruyama, K Sugio, L Yoshino, Y Maehara, AF Gazdar

CANCER, 100(7) 1472-1477, Apr, 2004
A variant from of hMTH1, a human homologue of E. coil mutT gene, correlates with somatic mutation in p53 tumour suppressor gene in gastric cancer patients

J Med Genetics, 41(5):e57, 2004
Abnormal PTEN expression in portal hypertensive gastric mucosa: A key to impaired PI 3-kinase/Akt activation and delayed injury healing?

K Tsugawa, MK Jones, T Akahoshi, WS Moon, Y Maehara, M Hashizume, IJ Sarfeh, AS Tarnawski

FASEB JOURNAL, 17(13) 2316-+, Oct, 2003
肝内胆管癌における新規Wntシグナル誘導遺伝子WISP1vの同定と機能解析

田中真二, 杉町圭史, 前原伸一郎, 調憲, 島田光生, 前原喜彦

日本癌学会総会記事, 62回 182-182, Aug, 2003
Gastrointestinal cancer and herpes zoster in adults

M Yamamoto, H Mine, K Akazawa, Y Maehara, K Sugimachi

HEPATO-GASTROENTEROLOGY, 50(52) 1043-1046, Jul, 2003
Gastrointestinal cancer and herpes zoster in adults

M Yamamoto, H Mine, K Akazawa, Y Maehara, K Sugimachi

HEPATO-GASTROENTEROLOGY, 50(52) 1043-1046, Jul, 2003
Human WISP1v, a member of the CCN family, is associated with invasive cholangiocarcinoma

S Tanaka, K Sugimachi, T Kameyama, S Maehara, K Shirabe, M Shimada, Wands, JR, Y Maehara

HEPATOLOGY, 37(5) 1122-1129, May, 2003
抗癌剤gemcitabine感受性規定遺伝子の網羅的解析による治療指標の同定

前原伸一郎, 島田光生, 調憲, 田中真二, 斎藤芳郎, 高橋和彦, 前原喜彦

日本外科学会雑誌, 104(臨増) 286-286, Apr, 2003
Higher expression of rhoC is related to invasiveness in non-small cell lung carcinoma.

Clin Cancer Res, 9(14):5282-5286, 2003
WISP3 derived from microsatellite unstable gastric carcinoma.

Gastroenterology, 125(5):1563-1564, 2003
Role of Surgery in the patients with stage Ⅰ and Ⅱ primary gastric lymphoma

Hepato-Gastroenterol, (50) 877-882, 2003
Role of Surgery in the patients with stage Ⅰ and Ⅱ primary gastric lymphoma

Hepato-Gastroenterol, (50) 877-882, 2003
Increased expression of multidrug resistance-associated proteins in bladder cancer during clinical course and drug resistance to doxorubicin

Y Tada, M Wada, T Migita, J Nagayama, E Hinoshita, Y Mochida, Y Maehara, M Tsuneyoshi, M Kuwano, S Naito

INTERNATIONAL JOURNAL OF CANCER, 98(4) 630-635, Apr, 2002
Increased expression of multidrug resistance-associated proteins in bladder cancer during clinical course and drug resistance to doxorubicin

Y Tada, M Wada, T Migita, J Nagayama, E Hinoshita, Y Mochida, Y Maehara, M Tsuneyoshi, M Kuwano, S Naito

INTERNATIONAL JOURNAL OF CANCER, 98(4) 630-635, Apr, 2002
Combined evaluation of expressions of p53 and p21 proteins as prognostic factors for patients with gastric carcinoma

T Okuyama, Y Maehara, A Kabashima, Takahashi, I, Y Kakeji, K Sugimachi

ONCOLOGY, 63(4) 353-361, 2002
Variant WISPs as targets for gastrointestinal carcinomas

Gastroenterology, 12, 392-393, 2002
Combined evaluation of expressions of p53 and p21 proteins as prognostic factors for patients with gastric carcinoma

T Okuyama, Y Maehara, A Kabashima, Takahashi, I, Y Kakeji, K Sugimachi

ONCOLOGY, 63(4) 353-361, 2002
Variant WISPs as targets for gastrointestinal carcinomas

Gastroenterology, 12, 392-393, 2002

Professional Memberships

Research Projects

機能獲得型変異ｐ53が制御する癌幹細胞化の解明と治療戦略の確立

科学研究費助成事業, 挑戦的研究(萌芽), 日本学術振興会, Jun, 2022 - Mar, 2024

前原喜彦, 北尾洋之, 飯森真人, 沖英次
Identification for dysbiosis in oral bacterial flora of patients with oral squamous cell carcinoma and development of innovative combination oncoimmune therapy

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2020 - Mar, 2023
Potential novel angiogenic therapy through BubR1 gene transfer for Critical Limb Ischemia

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2020

Matsumoto Takuya
Development of Innovative Treatment Targeting the Sphere Formation Mechanism Involving Cancer Stem Cells

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (S), Japan Society for the Promotion of Science, May, 2015 - Mar, 2020

Maehara Yoshihiko
Development of the the innovative treatment and the proposal of the Self-niche hypothesis in refractory cancer

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2018

MAEHARA Yoshihiko
Multidisciplinary treatment focusing on impaired intrahepatic microcirculation and splenic dysfunction in liver cirrhosis and portal hypertension

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Kawanaka Hirofumi
The biological analysis of sugar chain signal between hepatic stelate cells and macrophages in the progression of liver fibrosis.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Shirabe Ken
Research and development of measuring systems of breast cancer by mimicking olfactory systems of nematode C. elegans

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Toko Kiyoshi, OKI Eiji, OKAMOTO Tatsuro, SHIMIZU Kuniyoshi, NAKANO Keiko, SANEMATSU Keisuke, HAYASHI Kenshi, ONODERA Takeshi, TAHARA Yusuke, YATABE Rui
General study on the 2016 Kumamoto earthquake and related activities

Grants-in-Aid for Scientific Research, Grant-in-Aid for Special Purposes, Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2017

SHIMIZU Hiroshi, UTSUGI Mitsuru, UYESHIMA Makoto, WANG Gonghui, HAZARIKA Hemanta, YADA Toshihumi, TAKAHASHI Kazuo
Mechanism of sarcopnia in outer space

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

YOSHIZUMI Tomoharu
Tumor suppression mechanism through anti-inflammation and anit-fibrosis in non-small cell lung cancer

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

SHOJI Fumihiro
Development of artificial bile duct which has transplantationable strength and biocompatibility by knitting of biocompatible material

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

Shirakigawa Nana, IDA Ryo, TOKUYAMA Keitaro, HIRAYAMA Takaaki, IMAI Daisuke, MORIYASU Hiroki, GAU Hiroaki, MIYATA Tatsunori, YAMAO Takanobu
Biomarker research for PD-1 inhibitor and new combination therapy anti-PD-1 and chemotherapeutic agents

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2016

Maehara Yoshihiko, IKEDA Tetsuo, KAWANAKA Hirofumi, OKI Eiji, OKANO Shinji
Role of age-associated BubR1 gene in atherogenesis and its molecular mechanism

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

Matsumoto Takuya, MAEHARA Yoshihiko, FURUYAMA Tadashi, FUKUNAGA Ryota
Molecular mechanism of autophagy during differentiation and induction of hepatic stem cells in liver injury and regeneration

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

Soejima Yuji, SHIRABE Ken, YOSHIZUMI Tomoharu, IKEGAMI Toru, IKEDA Tetsuo, MAEHARA Yoshihiko
Development of the innovative hybrid artificial liver with establishment of the hepatocyte strain from human iPS cells

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

YAMASHITA YOICHI, Yonemitsu Yoshikazu, Ikeda Tetsuo, Shirabe Ken, Maehara Yoshihiko
DNA mismatch repair gene analysis predicts the response to anticancer drug sensitivity in gastrointestinal cancers for tailored therapy.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2016

Kakeji Yoshihiro, KITAO Hiroyuki, IIMORI Makoto, SAEKI Hiroshi, TOKUNAGA Eriko, OKI Eiji, MAEHARA Yoshihiko, MORITA Masaru
ヒト癌免疫編成機構の分子機序解明と免疫合成致死を誘導する革新的免疫療法の研究開発

科学研究費助成事業, 基盤研究(C), 日本学術振興会, Apr, 2014 - Mar, 2015

岡野慎士, 前原喜彦, 池田哲夫, 調憲, 沖英次, 佐伯浩司, 森田勝
A phase II study of induction cisplatin plus TS-1 with concurrent radiotherapy (66Gy) followed by surgical resection in patients with superior sulcus tumor

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2015

TSUSHIMA Yukio, SUZUKI Kenji, TAKAMOCHI Kazuya, OH Shiaki, OKADA Morihito, IKEDA Norihiko, TANAKA Fumihiro, OKUMURA Sakae, NAKAMURA Haruhiko, SUZUKI Hiroyuki, NAKAMURA Hiroshige, IWATA Hisashi, TSUBOI Masahiro, SUGIO Kenji, MANIWA Yoshimasa, UEDA Kazuhiro, DOKI Yoshinori, MAEHARA Yoshihiko, UENO Tsuyoshi, TAKENOYAMA Mitsuhiro, URAMOTO Hidetaka, YOSHINO Ichiro, NAGASIMA Takuya, SHIONO Satoshi, MATSUURA Motoki, OKUMURA Norihito, HORIO Hirotoshi, INASAWA Keitaro, FUNAI Kazuhito, ITOU Hiroyuki
The development of the high precision navigation system of sentinel node in gastrointestinal cancer in an open MRI operating theater

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2015

KAKEJI Yoshihiro, TOMIKAWA Morimasa, IKEDA Tetsuo, NAGAO Yoshihiro, MAEHARA Yoshihiko, HASHIZUME Makoto, KUMASHIRO Ryuichi, OKI Eiji