2006年8月
Differentiation-inducing factor-1 alters canonical Wnt signaling and suppresses alkaline phosphatase expression in osteoblast-like cell lines
JOURNAL OF BONE AND MINERAL RESEARCH
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- 巻
- 21
- 号
- 8
- 開始ページ
- 1307
- 終了ページ
- 1316
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1359/JBMR.060512
- 出版者・発行元
- AMER SOC BONE & MINERAL RES
Because DIF-1 has been shown to affect Wnt/beta-catenin signaling pathway, the effects of DIF-1 on osteoblast-like cell lines, SaOS-2 and MC3T3-E1, were examined. We found that DIF-1 inhibited this pathway, resulting in the suppression of ALP promoter activity through the TCF/LEF binding site.
- リンク情報
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- DOI
- https://doi.org/10.1359/JBMR.060512
- CiNii Articles
- http://ci.nii.ac.jp/naid/10024315060
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/16869729
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000239299400015&DestApp=WOS_CPL
- ID情報
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- DOI : 10.1359/JBMR.060512
- ISSN : 0884-0431
- CiNii Articles ID : 10024315060
- PubMed ID : 16869729
- Web of Science ID : WOS:000239299400015